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USD 150 /hr
Hire Dr. Rosa D.
Portugal
USD 150 /hr
Scientific Consultant with 25+ years of laboratory and research experience
Profile Summary
Subject Matter Expertise
Services
Writing
Clinical Trial Documentation,
Medical Writing,
Non-Medical Regulatory Writing,
Technical Writing
Research
Scientific and Technical Research,
Systematic Literature Review
Consulting
Healthcare Consulting,
Operations Consulting,
Scientific and Technical Consulting,
Regulatory Consulting
Work Experience
Visiting Lecturer
Instituto Politécnico da Lusofonia
2023 - Present 
Scientific Director
Prime Matter Consulting Lda
July 2020 - Present
Researcher
Universidade de Lisboa Faculdade de Farmácia
June 2012 - Present
Post-Doctoral Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical
July 2021 - July 2022
Masters' Thesis Researcher
Universidade de Coimbra Faculdade de Medicina
September 2007 - September 2009
Academic Internship in Biochemistry
Instituto Portugues de Oncologia Fransisco Gentil
September 2004 - July 2005
Education
Post-graduate Degree on Higher Education Pedagogy (Instituto de Educação (Education Institute))
Universidade de Lisboa
July 2021 - July 2022
PhD in Pharmacy (specialty in Food Science) (Faculty of Pharmacy)
University of Lisbon
September 2012 - July 2019
M.S. Biochemistry (Faculty of Sciences and Technology)
University of Coimbra
September 2007 - September 2009
B.S. Biochemistry (Faculty of Sciences and Technology)
University of Coimbra
2000 - 2005
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Rosa Direito, Mônica Duarte da Silva, Christina Ramires Ferreira, Hianka Jasmyne Costa de Carvalho, Sandra Maria Barbalho, Rodrigo da Silva Nunes Barreto, Maria Angélica Miglino (2026). Exploratory Spatial Lipidomic Profiling Reveals Regional Metabolic Heterogeneity in a Canine Mixed Mammary Carcinoma . Veterinary Sciences.
Rosa Direito, João Paulo Ruiz Lucio de Lima Parra, Rodrigo Paolo Flores Abuna, Maria Angélica Miglino, Letícia Bandiera Arantes, Lucas Fornari Laurindo, Luciana Lamarão Damous, Matheus Henrique Hermínio Garcia, Sandra Maria Barbalho, Flávio Vieira Meirelles, et al. (2026). Artificial ovaries and the future of women's health: Shaping novel functions . Translational Research.
Rosa Direito, Irina Fernandes, Ana Iglesias-Mejuto, João M. P. Coelho, Catarina P. Reis (2026). Development and Characterization of Mesembryanthemum crystallinum L. Extract-Loaded Phytosomes for Enhanced Delivery of Antioxidant Compounds . Life.
Rosa Direito, Mônica Duarte da Silva, Thamires Santos da Silva, Claudemir Gregório Mendes, Maria Carolina Miglino Valbão, Abraham Kwame Badu-Tawiah, Lucas Fornari Laurindo, Sandra Maria Barbalho, Maria Angélica Miglino (2025). Advances in Understanding Long COVID: Pathophysiological Mechanisms and the Role of Omics Technologies in Biomarker Identification . Molecular Diagnosis & Therapy.
Rosa Direito, Lucas Fornari Laurindo, Victória Dogani Rodrigues, Rodrigo Haber Mellen, Rafael Santos de Argollo Haber, Vitor Engrácia Valenti, Lívia Fornari Laurindo, Eduardo Federighi Baisi Chagas, Camila Marcondes de Oliveira, Maria Angélica Miglino, et al. (2025). AdipoRon as a Novel Therapeutic Agent for Depression: A Comprehensive Review of Preclinical Evidence . Biomedicines.
Marina Ribas Losasso, Maria Luiza Cesto Parussolo, Antony Oliveira Silva, Karina Quesada, Claudia Rucco Penteado Detregiachi, Marcelo Dib Bechara, Nahum Méndez-Sánchez, Ludovico Abenavoli, Adriano Cressoni Araújo, et al., Rosa Direito (2025). Unraveling the Metabolic Pathways Between Metabolic-Associated Fatty Liver Disease (MAFLD) and Sarcopenia . International Journal of Molecular Sciences.
Rosa Direito, Lucas Fornari Laurindo, Enzo Pereira de Lima, Adriano Cressoni Araújo, Victória Dogani Rodrigues, Jefferson Aparecido Dias, Marcos Barbosa Tavares Filho, Debora Aparecida Pires de Campos Zuccari, Lívia Fornari Laurindo, Maria Angélica Miglino, et al. (2025). Targeting Muscle Regeneration with Small Extracellular Vesicles from Adipose Tissue-Derived Stem Cells—A Review . Cells.
Rosa Direito, Nathália Mendes Machado, Maria Vitória Barroso Oliveira, Karina Quesada, Jesselina Francisco dos Santos Haber, Ricardo José Tofano, Claudio José Rubira, Tereza Lais Menegucci Zutin, Eliana de Souza Bastos Mazuqueli Pereira, Camila Marcondes de Oliveira, et al. (2025). Assessing Omega-3 Therapy and Its Cardiovascular Benefits: What About Icosapent Ethyl? A Systematic Review and Meta-Analysis . Pharmaceuticals.
Rosa Direito, Enzo Pereira de Lima, Lucas Fornari Laurindo, Vitor Cavallari Strozze Catharin, Masaru Tanaka, Iris Jasmin Santos German, Caroline Barbalho Lamas, Elen Landgraf Guiguer, Adriano Cressoni Araújo, Adriana Maria Ragassi Fiorini, et al. (2025). Polyphenols, Alkaloids, and Terpenoids Against Neurodegeneration: Evaluating the Neuroprotective Effects of Phytocompounds Through a Comprehensive Review of the Current Evidence . Metabolites.
Rosa Direito, Lucas Fornari Laurindo, Otávio Augusto Garcia Simili, Adriano Cressoni Araújo, Elen Landgraf Guiguer, Vitor Engrácia Valenti, Vitor de Oliveira, Juliana Santos de Oliveira, José Luiz Yanaguizawa Junior, Jefferson Aparecido Dias, et al. (2025). Melatonin from Plants: Going Beyond Traditional Central Nervous System Targeting—A Comprehensive Review of Its Unusual Health Benefits . Biology.
Lopes, M.R., Direito, R., Guiguer, E.L., Catharin, V.C.S., Zutin, T.L.M., Rubira, C.J., Catharin, V.M.C.S., Sloan, K.P., Sloan, L.A., Junior, J.L.Y., et al.(2025). Bridging the Gut Microbiota and the Brain, Kidney, and Cardiovascular Health: The Role of Probiotics . Probiotics and Antimicrobial Proteins.
Laurindo, L.F., Rodrigues, V.D., Guiguer, E.L., Laurindo, L.F., de Campos Zuccari, D.A.P., Detregiachi, C.R.P., Araújo, A.C., da Silva Camarinha Oliveira, J., Maria, D.A., Dias, J.A., et al.(2025). Catalpol: An Iridoid Glycoside With Potential in Combating Cancer Development and Progression—A Comprehensive Review . Phytotherapy Research. 39. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4950-4971.
Fornari Laurindo, L., Fornari Laurindo, L., Dogani Rodrigues, V., da Silva Camarinha Oliveira, J., Leme Boaro, B., Cressoni Araújo, A., Landgraf Guiguer, E., Rucco Penteado Detregiachi, C., Maria Cavallari Strozze Catharin, V., Federighi Baisi Chagas, E., et al.(2025). Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies . Frontiers in Nutrition. 12.
Laurindo, L.F., Pomini, K.T., de Lima, E.P., Laurindo, L.F., Rodrigues, V.D., da Silva Camarinha Oliveira, J., Araújo, A.C., Guiguer, E.L., Rici, R.E.G., Maria, D.A., et al.(2025). Isoorientin: Unveiling the hidden flavonoid's promise in combating cancer development and progression – A comprehensive review . Life Sciences. 360.
Direito, R., Sousa, I., Antunes, F., Barbalho, S.M., Simões, S., Bronze, M.R., Reis, C., Gaspar, M.M., Figueira, M.E.(2025). Phytosomal delivery enhances bioactivity of Hylocereus costaricensis phenolic extract . Frontiers in Nutrition. 12.
Direito, R., Rocha, J., de Melo, I.A., Gonçalves, M., Duarte, M.P., Fernandes, A., Sepodes, B., Figueira, M.-E.(2025). Oral Salvia officinalis phenolics abolish mortality and mitigate inflammation in acute TNBS murine colitis . Fitoterapia. 187.
Laurindo, L.F., Rodrigues, V.D., Laurindo, L.F., Cherain, L.M.A., de Lima, E.P., Boaro, B.L., da Silva Camarinha Oliveira, J., Chagas, E.F.B., Catharin, V.C.S., dos Santos Haber, J.F., et al.(2025). Targeting AMPK with Irisin: Implications for metabolic disorders, cardiovascular health, and inflammatory conditions — A systematic review . Life Sciences. 360.
Rosa Direito, Lucas Fornari Laurindo, Larissa Naomi Takeda, Nathalia Mendes Machado, Alda Maria Machado Bueno Otoboni, Ricardo de Alvares Goulart, Vitor Cavallari Strozze Catharin, Luís R. Silva, Sandra Maria Barbalho (2024). Health benefits of acerola (Malpighia spp) and its by-products: A comprehensive review of nutrient-rich composition, pharmacological potential, and industrial applications . Food Bioscience.
Rosa Direito, Iris Jasmin Santos German, Sandra Maria Barbalho, Jesus Carlos Andreo, Tereza Lais Menegucci Zutin, Lucas Fornari Laurindo, Victória Dogani Rodrigues, Adriano Cressoni Araújo, Elen Landgraf Guiguer, Karina Torres Pomini, et al. (2024). Exploring the Impact of Catechins on Bone Metabolism: A Comprehensive Review of Current Research and Future Directions . Metabolites.
Rosa Direito, Raissa Bulaty Tauil, Paula Takano Golono, Enzo Pereira de Lima, Ricardo de Alvares Goulart, Elen Landgraf Guiguer, Marcelo Dib Bechara, Claudia C. T. Nicolau, José Luiz Yanaguizawa Junior, Adriana M. R. Fiorini, et al. (2024). Metabolic-Associated Fatty Liver Disease: The Influence of Oxidative Stress, Inflammation, Mitochondrial Dysfunctions, and the Role of Polyphenols . Pharmaceuticals.
Rosa Direito, Raquel Rodrigues, Maria Eduardo Figueira, Andreia Bento-Silva, Ricardo Boavida Ferreira, Ana Cristina Ribeiro (2024). Exploring Lectin Bioactivity and Total Phenolic Compounds in Kiwifruit (Actinidia deliciosa var. Hayward) . Nutrients.
Direito, Rosa, Barbalho, Sandra Maria, Sepodes, Bruno, Figueira, Maria Eduardo (2024). Plant-Derived Bioactive Compounds: Exploring Neuroprotective, Metabolic, and Hepatoprotective Effects for Health Promotion and Disease Prevention . Preprints.org.
Direito, Rosa, Barbalho, Sandra Maria, Sepodes, Bruno, Figueira, Maria Eduardo (2024). Plant-Derived Bioactive Compounds: Exploring Neuroprotective, Metabolic, and Hepatoprotective Effects for Health Promotion and Disease Prevention . Pharmaceutics.
Direito, Rosa, de Oliveira Pagotto, Guilherme Lopes, Oliveira dos Santos, Livia Maria, Osman, Najwa, Lamas, Caroline Barbalho, Laurindo, Lucas Fornari, Pomini, Karina Torres, Guissoni, Leila M., de Lima, Enzo Pereira, Goulart, Ricardo de Alvares, et al. (2024). <i>Ginkgo biloba</i>: A Leaf of Hope in the Fight against Alzheimer's Dementia: Clinical Trial Systematic Review . Antioxidants.
Direito, Rosa, Pagotto, Guilherme Lopes de Oliveira, dos Santos, Livia Maria Oliveira, Osman, Najwa, Lamas, Caroline Barbalho, Laurindo, Lucas Fornari, Pomini, Karina Torres, Guissoni, Leila M., de Lima, Enzo Pereira, Goulart, Ricardo de Alvares, et al. (2024). Ginkgo biloba: A Leaf of Hope in the Fight Against Alzheimer’s Dementia: Clinical Trial Systematic Review . Preprints.org.
Laurindo, L.F., Direito, R., Bueno Otoboni, A.M.M., Goulart, R.A., Quesada, K., Barbalho, S.M.(2024). Grape Processing Waste: Effects on Inflammatory Bowel Disease and Colorectal Cancer . Food Reviews International. 40. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 336-369.
Direito, Rosa, Valotto Neto, Luiz Jose, Reverete de Araujo, Matheus, Moretti Junior, Renato Cesar, Mendes Machado, Nathalia, Joshi, Rakesh Kumar, dos Santos Buglio, Daiane, Barbalho Lamas, Caroline, Fornari Laurindo, Lucas, Tanaka, Masaru, et al. (2024). Investigating the Neuroprotective and Cognitive-Enhancing Effects of <i>Bacopa monnieri</i>: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis . Antioxidants.
Direito, Rosa, Neto, Luiz José Valotto, Reverete, Matheus, Junior, Renato Cesar Moretti, Machado, Nathalia Mendes, Joshi, Rakesh Kumar, Buglio, Daiane dos Santos, Lamas, Caroline Barbalho, Laurindo, Lucas Fornari, Tanaka, Masaru, et al. (2024). The Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review . Preprints.org.
Laurindo, L.F., de Lima, E.P., Laurindo, L.F., Rodrigues, V.D., Chagas, E.F.B., de Alvares Goulart, R., Araújo, A.C., Guiguer, E.L., Pomini, K.T., Rici, R.E.G., et al.(2024). The therapeutic potential of bee venom-derived Apamin and Melittin conjugates in cancer treatment: A systematic review . Pharmacological Research. 209.
Rosa Direito, Lucas Fornari Laurindo, Gabriel Magno de Carvalho, Bárbara de Oliveira Zanuso, Maria Eduardo Figueira, Ricardo de Alvares Goulart, Daiene Santos Buglio, Sandra Maria Barbalho (2023). Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review . Pharmaceutics.
Rosa Direito, Daniela Franceschi Nishikito, Ana Claudia Abdalla Borges, Lucas Fornari Laurindo, Alda M. M. Bueno Otoboni, Ricardo de Alvares Goulart, Claudia C. T. Nicolau, Adriana M. R. Fiorini, Renata Vargas Sinatora, Sandra M. Barbalho (2023). Anti-Inflammatory, Antioxidant, and Other Health Effects of Dragon Fruit and Potential Delivery Systems for Its Bioactive Compounds . Pharmaceutics.
Rosa Direito, Lucas Fornari Laurindo, Gabriel Magno de Carvalho, Bárbara de Oliveira Zanuso, Maria Eduardo Figueira, Ricardo de Alvares Goulart, Daiene Santos Buglio, Sandra Maria Barbalho (2023). Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review . Pharmaceutics.
Rosa Direito, Daniela Franceschi Nishikito, Ana Claudia Abdalla Borges, Lucas Fornari Laurindo, Alda M. M. Bueno Otoboni, Ricardo de Alvares Goulart, Claudia C. T. Nicolau, Adriana M. R. Fiorini, Renata Vargas Sinatora, Sandra M. Barbalho (2023). Anti-inflammatory, Antioxidant, and Other Health Effects of Dragon Fruit and Potential Delivery Systems for Its Bioactive Compounds . Pharmaceutics.
Drafi, F., Bauerova, K., Chrastina, M., Taghdisiesfejír, M., Rocha, J., Direito, R., Figueira, M.E., Sepodes, B., Ponist, S.(2023). Rhodiola rosea L. Extract, a Known Adaptogen, Evaluated in Experimental Arthritis . Molecules. 28. (13).
Ayvaz, H., Cabaroglu, T., Akyildiz, A., Pala, C.U., Temizkan, R., Ağçam, E., Ayvaz, Z., Durazzo, A., Lucarini, M., Direito, R., et al.(2023). Anthocyanins: Metabolic Digestion, Bioavailability, Therapeutic Effects, Current Pharmaceutical/Industrial Use, and Innovation Potential . Antioxidants. 12. (1).
Direito, R., Barbalho, S.M., Figueira, M.E., Minniti, G., de Carvalho, G.M., de Oliveira Zanuso, B., de Oliveira dos Santos, A.R., de Góes Corrêa, N., Rodrigues, V.D., de Alvares Goulart, R., et al.(2023). Medicinal Plants, Phytochemicals and Regulation of the NLRP3 Inflammasome in Inflammatory Bowel Diseases: A Comprehensive Review . Metabolites. 13. (6).
Nishikito, D.F., Borges, A.C.A., Laurindo, L.F., Otoboni, A.M.M.B., Direito, R., Goulart, R.D.A., Nicolau, C.C.T., Fiorini, A.M.R., Sinatora, R.V., Barbalho, S.M.(2023). Anti-Inflammatory, Antioxidant, and Other Health Effects of Dragon Fruit and Potential Delivery Systems for Its Bioactive Compounds . Pharmaceutics. 15. (1).
Laurindo, L.F., de Carvalho, G.M., de Oliveira Zanuso, B., Figueira, M.E., Direito, R., de Alvares Goulart, R., Buglio, D.S., Barbalho, S.M.(2023). Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review . Pharmaceutics. 15. (1).
Rosa Direito, Huseyin Ayvaz, Turgut Cabaroglu, Asiye Akyildiz, Cigdem Uysal Pala, Riza Temizkan, Erdal Ağçam, Zayde Ayvaz, Alessandra Durazzo, Massimo Lucarini, et al. (2022). Anthocyanins: Metabolic Digestion, Bioavailability, Therapeutic Effects, Current Pharmaceutical/Industrial Use, and Innovation Potential . Antioxidants.
Rosa Direito, Huseyin Ayvaz, Turgut Cabaroglu, Asiye Akyildiz, Cigdem Uysal Pala, Riza Temizkan, Erdal Ağçam, Zayde Ayvaz, Alessandra Durazzo, Massimo Lucarini, et al. (2022). Anthocyanins: Metabolic Digestion, Bioavailability, Therapeutic Effects, Current Pharmaceutical/Industrial Use, and Innovation Potential . Antioxidants.
Rosa Direito, Sandra Maria Barbalho, Lucas Fornari Laurindo, Ledyane Taynara Marton, Elen Landgraf Guiguer, Ricardo de Alvares Goulart, Ricardo José Tofano, Antonely C. A. Carvalho, Uri Adrian Prync Flato, Viviane Alessandra Capelluppi Tofano, et al.(2022). Ginkgo biloba in the Aging Process: A Narrative Review . Antioxidants. 11. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 525. {MDPI} {AG}
Rosa Direito, Sandra Maria Barbalho, Lucas Fornari Laurindo, Ledyane Taynara Marton, Elen Landgraf Guiguer, Ricardo de Alvares Goulart, Ricardo José Tofano, Antonely C. A. Carvalho, Uri Adrian Prync Flato, Viviane Alessandra Capelluppi Tofano, et al. (2022). <i>Ginkgo biloba</i> in the Aging Process: A Narrative Review . Antioxidants.
Barbalho, S.M., Direito, R., Laurindo, L.F., Marton, L.T., Guiguer, E.L., Goulart, R.A., Tofano, R.J., Carvalho, A.C.A., Flato, U.A.P., Tofano, V.A.C., et al.(2022). Ginkgo biloba in the Aging Process: A Narrative Review . Antioxidants. 11. (3).
Rosa Direito, Joana Mota, João Rocha, João Fernandes, Bruno Sepodes, Maria Eduardo Figueira, Anabela Raymundo, Ana Lima, Ricardo Boavida Ferreira (2021). Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo . International Journal of Molecular Sciences.
Rosa Direito, Joana Mota, João Rocha, João Fernandes, Bruno Sepodes, Maria Eduardo Figueira, Anabela Raymundo, Ana Lima, Ricardo Boavida Ferreira (2021). <i>Lupinus albus</i> Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo . International Journal of Molecular Sciences.
Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo-Figueira (2021). From Diospyros kaki L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization . Nutrients.
Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo-Figueira (2021). From <i>Diospyros kaki</i> L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization . Nutrients.
Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo-Figueira(2021). Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation . Pharmaceutics. 13. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 145. {MDPI} {AG}
Rosa Direito, João Rocha, Bruno Sepodes, Maria Eduardo-Figueira (2021). Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation . Pharmaceutics.
Mota, J., Direito, R., Rocha, J., Fernandes, J., Sepodes, B., Figueira, M.E., Raymundo, A., Lima, A., Ferreira, R.B.(2021). Lupinus albus protein components inhibit MMP-2 and MMP-9 gelatinolytic activity in vitro and in vivo . International Journal of Molecular Sciences. 22. (24).
Rosa Direito, João Rocha, Raquel Leandro, Margarida Gonçalves, Maria Paula Duarte, Adelaide Fernandes, Bruno Sepodes, Maria-Eduardo Figueira(2020). Attenuation of Colonic Injury and Inflammation by Administration of a Phenolic Extract of Summer Savory (Satureja hortensis L.) in Experimental Inflammatory Bowel Disease in Mice . Applied Sciences. 10. (23). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8465. {MDPI} {AG}
Rosa Direito, João Rocha, Ana-Teresa Serra, Adelaide Fernandes, Marisa Freitas, Eduarda Fernandes, Rui Pinto, Rosário Bronze, Bruno Sepodes, Maria-Eduardo Figueira(2020). Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis . Journal of Dietary Supplements. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--21. Informa {UK} Limited
Rosa Direito, João Rocha, Raquel Leandro, Margarida Gonçalves, Maria Paula Duarte, Adelaide Fernandes, Bruno Sepodes, Maria-Eduardo Figueira (2020). Attenuation of Colonic Injury and Inflammation by Administration of a Phenolic Extract of Summer Savory (<i>Satureja hortensis</i> L.) in Experimental Inflammatory Bowel Disease in Mice . Applied Sciences.
Direito, R., Rocha, J., Serra, A.-T., Fernandes, A., Freitas, M., Fernandes, E., Pinto, R., Bronze, R., Sepodes, B., Figueira, M.-E.(2020). Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis . Journal of Dietary Supplements. 17. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 663-683.
Rocha, J., Leandro, R., Direito, R., Gonçalves, M., Duarte, M.P., Fernandes, A., Sepodes, B., Figueira, M.-E.(2020). Attenuation of colonic injury and inflammation by administration of a phenolic extract of summer savory (Satureja hortensis l.) in experimental inflammatory bowel disease in mice . Applied Sciences (Switzerland). 10. (23). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1-19.
(2019). Anti-inflammatory activity of grapefruit juice in an in vivo model of ulcerative colitis: Comparability studies of unprocessed and bioprocessed juices . Journal of Functional Foods.
Rosa Direito, Catarina Reis, Luís Roque, Margarida Gonçalves, Ana Sanches-Silva, Maria Manuela Gaspar, Rui Pinto, João Rocha, Bruno Sepodes, Maria Rosário Bronze, et al. (2019). Phytosomes with Persimmon (Diospyros kaki L.) Extract: Preparation and Preliminary Demonstration of In Vivo Tolerability . Pharmaceutics.
Rosa Direito, João Rocha, Ana Lima, Maria Margarida Gonçalves, Maria Paula Duarte, Vanessa Mateus, Catarina Sousa, Adelaide Fernandes, Rui Pinto, Ricardo Boavida Ferreira, et al.(2019). Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice . Medicines. 6. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 65. {MDPI} {AG}
Rosa Direito, João Rocha, Ana Lima, Maria Margarida Gonçalves, Maria Paula Duarte, Vanessa Mateus, Catarina Sousa, Adelaide Fernandes, Rui Pinto, Ricardo Boavida Ferreira, et al. (2019). Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice . Medicines.
Rosa Direito, Catarina Reis, Luís Roque, Margarida Gonçalves, Ana Sanches-Silva, Maria Manuela Gaspar, Rui Pinto, João Rocha, Bruno Sepodes, Maria Rosário Bronze, et al. (2019). Phytosomes with Persimmon (<i>Diospyros kaki</i> L.) Extract: Preparation and Preliminary Demonstration of In Vivo Tolerability . Pharmaceutics.
Mota, A.H., Direito, R., Carrasco, M.P., Rijo, P., Ascensão, L., Viana, A.S., Rocha, J., Eduardo-Figueira, M., Rodrigues, M.J., Custódio, L., et al.(2019). Combination of hyaluronic acid and PLGA particles as hybrid systems for viscosupplementation in osteoarthritis . International Journal of Pharmaceutics. 559. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13-22.
Rocha, J., Direito, R., Lima, A., Mota, J., Gonçalves, M., Duarte, M.P., Solas, J., Peniche, B.F., Fernandes, A., Pinto, R., et al.(2019). Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice . Biomedicine and Pharmacotherapy. 118.
(2019). Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice . Medicines.
Mendes, C., Rocha, J., Direito, R., Fernandes, A., Sepodes, B., Figueira, M.-E., Ribeiro, M.H.(2019). Anti-inflammatory activity of grapefruit juice in an in vivo model of ulcerative colitis: Comparability studies of unprocessed and bioprocessed juices . Journal of Functional Foods. 63.
Direito, R., Reis, C., Roque, L., Gonçalves, M., Sanches-Silva, A., Gaspar, M.M., Pinto, R., Rocha, J., Sepodes, B., Bronze, M.R., et al.(2019). Phytosomes with persimmon (Diospyros kaki l.) extract: Preparation and preliminary demonstration of in vivo tolerability . Pharmaceutics. 11. (6).
Vieira da Silva, S.A., Clemente, A., Rocha, J., Direito, R., Marques, H.C., Sepodes, B., Figueira, M.-E., Ribeiro, M.H.(2018). Anti-inflammatory effect of limonin from cyclodextrin (un)processed orange juices in in vivo acute inflammation and chronic rheumatoid arthritis models . Journal of Functional Foods. 49. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 146-153.
Direito R, Lima A, Rocha J, Ferreira RB, Mota J, Rebelo P, Fernandes A, Pinto R, Alves P, Bronze R, et al.(2017). Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities . The Journal of nutritional biochemistry.
Direito, R., Lima, A., Rocha, J., Ferreira, R.B., Mota, J., Rebelo, P., Fernandes, A., Pinto, R., Alves, P., Bronze, R., et al.(2017). Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities . Journal of Nutritional Biochemistry. 46. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 100-108.
Rosa Direito, Maria-Eduardo Figueira, Mónica Oliveira, João Rocha, Paula Alves, Ana-Teresa Serra, Catarina Duarte, Rosário Bronze, Adelaide Fernandes, Dora Brites, et al. (2016). Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat . Biomedicine & Pharmacotherapy.
Figueira, M.-E., Oliveira, M., Direito, R., Rocha, J., Alves, P., Serra, A.-T., Duarte, C., Bronze, R., Fernandes, A., Brites, D., et al.(2016). Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat . Biomedicine and Pharmacotherapy. 83. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1191-1202.
Silva, S., Sepodes, B., Rocha, J., Direito, R., Fernandes, A., Brites, D., Freitas, M., Fernandes, E., Bronze, M.R., Figueira, M.E.(2015). Protective effects of hydroxytyrosol-supplemented refined olive oil in animal models of acute inflammation and rheumatoid arthritis . Journal of Nutritional Biochemistry. 26. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 360-368.
Figueira, M.E., Câmara, M.B., Direito, R., Rocha, J., Serra, A.T., Duarte, C.M.M., Fernandes, A., Freitas, M., Fernandes, E., Marques, M.C., et al.(2014). Chemical characterization of a red raspberry fruit extract and evaluation of its pharmacological effects in experimental models of acute inflammation and collagen-induced arthritis . Food and Function. 5. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3241-3251.
Rocha, J., Barateiro, A., Fernandes, A., Raposo, J., Direito, R., Eduardo-Figueira, M., Pinto, R., Thiemermann, C., Mota-Filipe, H., Sepodes, B. (2013). GLYCOGEN SYNTHASE KINASE-3 INHIBITION REDUCES LIVER, NEUROMUSCULAR, AND LUNG INJURY CAUSED BY BURN INJURY IN THE RAT . Shock.
Alves, G., Fortuna, A., Sousa, J., Direito, R., Almeida, A., Rocha, M., Falcão, A., Soares-Da-Silva, P.(2010). Enantioselective assay for therapeutic drug monitoring of eslicarbazepine acetate: No interference with carbamazepine and its metabolites . Therapeutic Drug Monitoring. 32. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 512-516.
CONFERENCE ABSTRACT
IMMUNOMODULATION OF CANINE MONOCYTE-DERIVED DENDRITIC CELLS BY LEISHMANIA INFANTUM AND L. AMAZONENSIS @inproceedings {
author = {Ana Valério-Bolas and Meunier, Mafalda and Direito, Rosa and Joana Palma-Marques and Lobo, Lis and Armanda Viana Rodrigues and Marta Monteiro and et al.},
title = {IMMUNOMODULATION OF CANINE MONOCYTE-DERIVED DENDRITIC CELLS BY LEISHMANIA INFANTUM AND L. AMAZONENSIS },
address = {Cartagena},
pages = {771--772},
year = {2022},
month = {aug}
}. WolrdLeish7.
(2020). Reduction of inflammation and colon injury by a Satureja hortensis L. (Savory) phenolic extract in experimental inflammatory bowel disease in mice. Iberphenol International Conference.
(2020). Nanocarriers with Sambucus nigra L. extract for anti-inflammatory activity. 12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology.
(2020). Skin Delivery of Sambucus nigra L. extracts through nanocarriers. 5th World Congress & Expo on Pharmaceutics & Drug Delivery Systems.
(2019). Phytosomes with Persimmon (Diospyros kaki, L.) Extract: Preparation and Preliminary Demonstration of in vivo Tolerability. 13th World Congress on Polyphenols Applications.
(2019). Deflamin, a Non-Toxic Oglimer from Lupinus Albus Seeds, Resists Digestion and Inhibits Colitis by Targeting MMP-9 Activity in vitro and in vivo. World Congress of Gastroenterology.
(2019). Evaluation of the Anti-Inflammatory Activity of a Persimmon (Diospyros kaki, L.) Extract in Colitis and Rheumatoid Arthritis Rodent Models. Natural Products in Drug Discovery and Human Health conference organized by Portuguese Chemistry Society.
(2019). Phytosomes with Persimmon (Diospyros kaki L.) Extract: Preparation, Characterization and In Vivo Preliminary Tolerability. 3rd Edition of the Master activity of the Lusophone Academy of Pharmaceutical Sciences.
(2018). Phytosomes with Diospyros kaki Phenolic Extract: Preparation and Characterization. 10th iMed.ULisboa and 3rd i3du Postgraduate Students Meeting.
(2017). Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities . Annual Reunion of the Portuguese Pharmacology Society.
(2014). Transient and Lasting Neurodegenerative Effects of Chronic Systemic Inflammation in Early Neonatal Mice. 6th iMed.UL Postgraduate Students Meeting.
(2013). Evaluation of the anti-inflammatory activity of a persimmon (Diospyros kaki, L.) extract in an animal (Wistar rats) model of rheumatoid arthritis. XLIII Annual Meeting of the Portuguese Pharmacological Society; XXXI Clinical Pharmacology Meeting; XII Toxicology Meeting, UMIB, ICBAS-University of Porto.
(2013). Glycogen synthase kinase-3 inhibition reduces liver, neuromuscular and lung injury caused by burn injury in the rat. The European Shock Society’s 15th biannual conference.
(2011). The effect of raspberry in the postprandial inflammation in healthy humans.
(2011). Phenolic compounds in raspberry samples – possible contribution to biological activity. Iberoamerican Conference from the Faculty of Pharmacy, Lisbon.
CONFERENCE POSTER
Immunomodulation of canine monocyte-derived dentritic cells by Leishmania infantum and L.amazonensis @misc {
author = {Ana Valério-Bolas and Meunier, Mafalda and Direito, Rosa and Joana Palma-Marques and Lobo, Lis and Armanda Rodrigues and Monteiro, Marta and et al.},
title = {Immunomodulation of canine monocyte-derived dentritic cells by Leishmania infantum and L.amazonensis},
year = {2022},
month = {aug}
}. 7th World Congress on Leishmaniasis.
Leishmania infantum e L. amazonensis induzem a maturação de células dendríticas e o recrutamento de linfócitos T ativados @misc {
author = {Ana Valério-Bolas and Meunier, Mafalda and Direito, Rosa and Joana Palma-Marques and Lobo, Lis and Rodrigues, Armanda and Rui Ferreira and et al. Corresponding author: Ana Valério-Bolas.},
title = {Leishmania infantum e L. amazonensis induzem a maturação de células dendríticas e o recrutamento de linfócitos T ativados},
year = {2021},
month = {dec}
}. XII Jornadas Científicas do IHMT.
(2019). Nanocarriers with Sambucus nigra L. Extracts for Skin Applications. 26th International Conference on Bioencapsulation.
(2016). Intestinal Anti-inflammatory Activity of Grapefruit Juice in a Model of Rat Colitis.
(2014). Inflammation associated events and neurovascular disruption in neonatal sepsis. Barriers of the CNS Gordon Research Conference Expanding the Understanding of CNS Barriers in Health and Disease.
(2013). Neonatal sepsis changes the pattern of microvascular coverage by astrocytes and microglia. 5th Post-Graduate iMed.UL Students Meeting, Lisbon, Portugal.
(2013). Neonatal Systemic Inflammation Differently Alters Regional Brain Microvasculature. Workshop Beating the blood-brain & other blood barriers.
(2011). Phenolic compounds in raspberry samples – possible contribution to biological activity. Iberoamerican Conference from the Faculty of Pharmacy, Lisbon.
(2010). Morphological evaluation of rat liver tissue after the subcutaneous injection of 1,2-dimethylhydrazine. 16th World Congress of Basic and Clinical Pharmacology”, Copenhagen.
BOOK CHAPTER
(2019). CARACTERIZAÇÃO QUÍMICA E AVALIAÇÃO DA ATIVIDADE BIOLÓGICA DA FRAMBOESA (RUBUS IDAEUS L.). CONTRIBUIÇÃO PARA O DESENVOLVIMENTO DE UMA ALEGAÇÃO DE SAÚDE . A produção do Conhecimento nas Ciências Agrárias e Ambientais 2.
CONFERENCE PAPER
(2013). Neonatal Exposure to LPS Alters Microvascular and Glial Patterns in Different Brain Regions. ESNI Course, Porto.
(2012). Systemic Inflammation in the Neonatal Period Causes Microvasculature Alterations that May Differ Between Brain Regions and Neonatal Age. 4th Postgraduate iMed.UL Students Meeting, Lisbon.
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