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Profile Details
Hire Dr. Estela B.
Brazil
Medical and scientific writer with 10+ years of experience in research. PhD with 40 publications (12 as 1st author).
Profile Summary
Subject Matter Expertise
Services
Writing
Clinical Trial Documentation,
Technical Writing,
Copywriting
Research
Fact Checking,
Gray Literature Search,
Systematic Literature Review,
Secondary Data Collection
Consulting
Scientific and Technical Consulting
Work Experience
Clinical Trials Coordinator
Allergisa
September 2020 - Present
Postdoctoral Researcher
State University of Campinas (UNICAMP)
April 2014 - August 2020
Education
PhD in Biochemistry
Federal University of Rio Grande do Sul (UFRGS)
March 2011 - December 2012
Master in Biochemistry
Federal University of Rio Grande do Sul (UFRGS)
April 2009 - December 2012
Bachelor’s in Biomedical Science
Lutheran University of Brazil
March 2004 - August 2008
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
(2019). Leucine-rich diet induces a shift in tumour metabolism from glycolytic towards oxidative phosphorylation, reducing glucose consumption and metastasis in Walker-256 tumour-bearing rats . Scientific reports.
(2018). Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition . Free radical biology & medicine.
(2018). Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice . Frontiers in pharmacology.
(2018). Facilitation of Ca2+ -induced opening of the mitochondrial permeability transition pore either by nicotinamide nucleotide transhydrogenase deficiency or statins treatment . Cell biology international.
(2017). Pravastatin Chronic Treatment Sensitizes Hypercholesterolemic Mice Muscle to Mitochondrial Permeability Transition: Protection by Creatine or Coenzyme Q10 . Frontiers in Pharmacology.
(2014). Pristanic acid provokes lipid, protein, and DNA oxidative damage and reduces the antioxidant defenses in cerebellum of young rats . Cerebellum (London, England).
(2014). Disturbance of the glutamatergic system by glutaric acid in striatum and cerebral cortex of glutaryl-CoA dehydrogenase-deficient knockout mice: possible implications for the neuropathology of glutaric acidemia type I . Journal of the Neurological Sciences.
(2014). Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: a possible role of mPTP opening as a pathomechanism in these disorders? . Biochimica et biophysica acta.
(2013). Disruption of oxidative phosphorylation and synaptic Na(+), K(+)-ATPase activity by pristanic acid in cerebellum of young rats . Life sciences.
(2013). Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome . Life sciences.
(2013). Disruption of mitochondrial homeostasis by phytanic acid in cerebellum of young rats . Cerebellum (London, England).
(2013). In vivo experimental evidence that the major metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency induce oxidative stress in striatum of developing rats: a potential pathophysiological mechanism of striatal damage in this disorder . Molecular genetics and metabolism.
(2013). Neurotoxic effects of trans-glutaconic acid in rats . Oxidative medicine and cellular longevity.
(2012). Neurodevelopmental and cognitive behavior of glutaryl-CoA dehydrogenase deficient knockout mice . Life sciences.
(2012). Marked inhibition of Na+, K(+)- ATPase activity and the respiratory chain by phytanic acid in cerebellum from young rats: possible underlying mechanisms of cerebellar ataxia in Refsum disease . Journal of bioenergetics and biomembranes.
(2012). Long-chain 3-hydroxy fatty acids accumulating in long-chain 3-hydroxyacyl-CoA dehydrogenase and mitochondrial trifunctional protein deficiencies uncouple oxidative phosphorylation in heart mitochondria . Journal of bioenergetics and biomembranes.
(2012). Reduction of Na+, K+-ATPase activity and expression in cerebral cortex of glutaryl-CoA dehydrogenase deficient mice: a possible mechanism for brain injury in glutaric aciduria type I . Molecular genetics and metabolism.
(2012). Impairment of brain redox homeostasis caused by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome in vivo . Metabolic brain disease.
(2012). Chronic postnatal ornithine administration to rats provokes learning deficit in the open field task . Metabolic brain disease.
(2012). Marked reduction of Na(+), K(+)-ATPase and creatine kinase activities induced by acute lysine administration in glutaryl-CoA dehydrogenase deficient mice . Molecular genetics and metabolism.
(2011). Experimental evidence that pristanic acid disrupts mitochondrial homeostasis in brain of young rats . Journal of neuroscience research.
(2011). Toxicity of octanoate and decanoate in rat peripheral tissues: evidence of bioenergetic dysfunction and oxidative damage induction in liver and skeletal muscle . Molecular and cellular biochemistry.
(2011). Ethylmalonic acid impairs brain mitochondrial succinate and malate transport . Molecular genetics and metabolism.
(2011). 3-Methylcrotonylglycine disrupts mitochondrial energy homeostasis and inhibits synaptic Na(+),K (+)-ATPase activity in brain of young rats . Cellular and molecular neurobiology.
(2011). Neurochemical evidence that pristanic acid impairs energy production and inhibits synaptic Na(+), K(+)-ATPase activity in brain of young rats . Neurochemical research.
(2010). Dual mechanism of brain damage induced in vivo by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome . Brain research.
(2010). In vitro evidence that phytanic acid compromises Na(+),K(+)-ATPase activity and the electron flow through the respiratory chain in brain cortex from young rats . Brain research.
(2010). Disturbance of mitochondrial energy homeostasis caused by the metabolites accumulating in LCHAD and MTP deficiencies in rat brain . Life sciences.
(2010). Neurochemical evidence that glycine induces bioenergetical dysfunction . Neurochemistry international.
(2010). Long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies induce oxidative stress in rat brain . Neurochemistry international.
(2009). Promotion of lipid and protein oxidative damage in rat brain by ethylmalonic acid . Neurochemical research.
(2009). In vitro evidence that D-serine disturbs the citric acid cycle through inhibition of citrate synthase activity in rat cerebral cortex . Brain research.
(2009). Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain . Brain research.
(2009). Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson's disease . Metabolic brain disease.
(2009). Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain . Neurochemistry international.
(2008). Amino acids levels and lipid peroxidation in maple syrup urine disease patients . Clinical biochemistry.
(2008). Selective screening for organic acidemias by urine organic acid GC-MS analysis in Brazil: fifteen-year experience . Clinica chimica acta; international journal of clinical chemistry.
(2008). Chronic early postnatal administration of ethylmalonic acid to rats causes behavioral deficit . Behavioural brain research.
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