Profile Details

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Hire Dr. Avinash P.

United Kingdom

USD 15 /hr

Protein Engineer | Structural & Molecular Biologist | Biochemist | Drug Discovery Scientist

Profile Summary

A cross-functional research scientist with over 10 years of experience in molecular and structural biology, biochemistry and bioinformatics. Proficient in recombinant protein expression and purification, macromolecular crystallisation and structure determination using X-ray crystallography.

Subject Matter Expertise

• ★ Structural Biology
• ★ Bioinformatics
• ★ Drug Design
• ☆ Molecular Modeling
• ☆ Separation & Purification
• ☆ X-Ray Crystallography
• ☆ Computational Chemistry
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ PCR
• ☆ Recombinant Protein Expression
• ☆ Image Processing
• ☆ Book Reviews
• ☆ LaTex
• ☆ Medicinal Chemistry
• ☆ Drug Development
• ☆ Antibiotic Development
• ☆ Research
• ☆ Peer Review
• ☆ Scientific Animation & Illustration
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Scientific Proofreading & Editing
• ☆ Grant Writing

Services

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing, Newswriting

Research Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Product Development Formulation

Work Experience

Research

University of Dundee

April 2018 - Present

Research Fellow

University of Warwick

March 2016 - March 2018

Postdoctoral Research Scientist

Research Complex at Harwell

January 2015 - February 2016

Researcher

Uppsala University

March 2014 - November 2014

Research and Teaching Assistant

Uppsala University

November 2008 - February 2014

Scientific Content Specialist

Eidogen-Sertanty Inc.

June 2005 - July 2006

Lecturer

Rai University

February 2004 - May 2005

Research Fellow

SIES-Indian Institute of Environment Management

January 2003 - January 2004

Education

Doctor of Philosophy - PhD, Structural Biology (Macromolecular Crystallography)

Uppsala University

November 2008 - February 2014

Master of Science - MSc, Molecular Biotechnology and Bioinformatics

Uppsala University

August 2006 - August 2008

Postgraduate Diploma - PGDip, Bioinformatics

SIES - Indian Institute of Environment Management

January 2002 - December 2002

Bachelor of Pharmacy - BPharm

Savitribai Phule Pune University

June 1997 - May 2001

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Avinash Punekar, Anita C Catherwood, Adrian J Lloyd, Julie A Tod, Smita Chauhan, Susan E Slade, Gregory Walkowiak, Nicola F Galley, Katie Smart, Dean Rea, et al.(2020). Substrate and stereochemical control of peptidoglycan crosslinking by transpeptidation by Escherichia coli PBP1B . Journal of the American Chemical Society. 142. (11). p. 5034--5048. American Chemical Society

Avinash Punekar, Ricky Cain, Ramya Salimraj, Dom Belini, Colin W. G. Fishwick, Lloyd Czaplewski, David J. Scott, Gemma Harris, Christopher G. Dowson, Adrian J. Lloyd, et al.(2019). Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase . Journal of Medicinal Chemistry. 62. (21). p. 9703--9717. American Chemical Society

(2019). Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase . Journal of medicinal chemistry.

Avinash Punekar, Firdaus Samsudin, Adrian J Lloyd, Christopher G Dowson, David J Scott, Syma Khalid, David I Roper(2018). The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization . Cell Surface. 2. p. 54--66. Elsevier

Avinash Punekar, Han Feng, Sheng Wang, Ling Guo, Rudolf Ladenstein, Da-Cheng Wang, Wei Liu(2016). MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction . Protein and Cell. 7. (12). p. 916--920. Springer-Verlag GmbH and Co. KG

Avinash Punekar, Jonathan Porter, Stephen B. Carr, Simon E. V. Phillips(2016). Structural basis for DNA recognition by the transcription regulator MetR . Acta Crystallographica Section F: Structural Biology Communications. F72. (6). p. 417--26. International Union of Crystallography

Avinash Punekar, Josefine Liljeruhm, Tyson R. Shepherd, Anthony C. Forster, Maria Selmer(2013). Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ . Nucleic Acids Research. 41. (20). p. 9537--9548. Oxford University Press

Avinash Punekar, Maria Selmer(2013). Purification . Acta Crystallographica F-Structural Biology and Crystallization Communications. 69. (Pt 9). p. 1001--1003. International Union of Crystallography

Avinash Punekar, Greta Hultqvist, S. Raza Haq, Celestine N. Chi, Åke Engström, Anders Bach, Kristian Strømgaard, Maria Selmer, Stefano Gianni, Per Jemth(2013). Energetic pathway sampling in a protein interaction domain . Structure. 21. (7). p. 1193--1202. Elsevier

Avinash Punekar, Tyson R. Shepherd, Josefine Liljeruhm, Anthony C. Forster, Maria Selmer(2012). Crystal structure of RlmM . Nucleic Acids Research. 40. (20). p. 10507--10520. Oxford University Press

Avinash Punekar, Greta Hultqvist, Angela Morrone, Celestine N. Chi, Ake Engström, Maria Selmer, Stefano Gianni, Per Jemth(2012). Tolerance of protein folding to a circular permutation in a PDZ domain . PLoS ONE. 7. (11). p. e50055. Public Library of Science

Avinash Punekar, M. Mohan, N. Kaul, R. Girnar, P. Junnare, L. Patil(2005). Nootropic activity of Moringa oleifera leaves . Journal of Natural Remedies. 5. (1). p. 59--62. Natural Remedies Private Ltd

OTHER

Avinash Punekar, Robert L. Summers, Manu Vanaerschot, James M. Murithi, Charisse F. Pasaje, Madeline R. Luth, Pamela Magistrado-Coxen, Emma F. Carpenter, Jade Bath, Joao P. Pisco, et al.(2019). IDENTIFICATION OF THE PLASMODIUM FALCIPARUM ACETYL-COA SYNTHETASE AS AN EMERGING ANTIPLASMODIAL DRUG TARGET . American Journal of Tropical Medicine and Hygiene. 101. (5 Suppl. 1). p. 476--477. American Society of Tropical Medicine and Hygiene