Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 50 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Aliya S.

United Kingdom

USD 50 /hr

Post-doctoral researcher with clinical expertise

Profile Summary

Dr Aliya Sarmanova is a Research Associate in Musculoskeletal and Clinical Outcomes working on the Wellcome Trust funded AUGMENT project. Her current research is focused on deriving joint shape and osteoarthritis-related features (i.e. osteophytes, joint space narrowing, subchondral sclerosis) using statistical shape modelling (SSM) on knee DXA scans obtained in UK Biobank. Other current projects include investigating confounding by population structure in genetic studies and causal inference (UK Biobank), and the association between genetic predisposition to osteoarthritis and musculoskeletal pain in adolescents (ALSPAC, GO Consortium). Aliya’s previous research was on osteoarthritis phenotypes including “inflammatory” changes in knee synovium detected by ultrasound and contribution of central pain mechanisms to knee pain severity and progression (Arthritis Research UK Pain Cetre), the effect of statins on risk of joint replacement (collaboration with Central South University in China), gout treatment (randomised controlled trial comparing nurse-led optimal care to general practitioner led usual care for people with gout, the Lancet, 2018). Aliya’s research interests include musculoskeletal epidemiology (osteoarthritis, gout, rheumatoid arthritis and fibromyalgia), big data analysis (CPRD, UK Biobank), causal inference (e.g. risk factors, pain mechanisms, placebo response), application of imaging (i.e. ultrasound, radiographs, DXA), clinical trials and genetics (heritability, GWAS, mendelian randomization). Biography Aliya graduated with a first class diploma (hons) in Internal Medicine in 2009 from the Astana Medical University, Kazakhstan. She completed rheumatologist training and worked in hospital and outpatient centre for 4 years in Kazakhstan. Her research career started in 2014 when she was awarded a prestigious Bolashak PhD scholarship with the Kazakhstan Government (2014-2017). Aliya completed her PhD in synovial changes on knee ultrasound in people with knee pain and the general population in the University of Nottingham.

Subject Matter Expertise

• ★ Health Data Analysis
• ★ Medicine
• ☆ Data Science
• ☆ Big Data Analytics
• ☆ Applied Statistics
• ☆ Clinical Trials
• ☆ Epidemiology
• ☆ Ultrasound
• ☆ Rheumatology
• ☆ Research
• ☆ Research Methodology
• ☆ Systematic Literature Review

Services

• Writing
• Research
• Data & AI

Writing Clinical Trial Documentation, Technical Writing, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis, Algorithm Design-Non ML, Data Visualization

Work Experience

University of Bristol

- Present

Research Fellow in Big Data

University of Nottingham

December 2017 - September 2018

Education

PhD in Medicine (Academic Rheumatology)

University of Nottingham

October 2014 - November 2017

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Aliya Sarmanova, Hunar Abdulrahim, Qiang Jiao, Subhashisa Swain, Khosrow Sehat, Kenneth Muir, Weiya Zhang, Michael Doherty (2020). Constitutional morphological features and risk of hip osteoarthritis: a case–control study using standard radiographs . Annals of the Rheumatic Diseases.

Aliya Sarmanova, Michael Doherty, Changfu Kuo, Jie Wei, Abhishek Abhishek, Christian Mallen, Chao Zeng, Yilun Wang, Guanghua Lei, Weiya Zhang(2020). Corrigendum to: Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study . Rheumatology. Oxford University Press ({OUP})

Aliya Sarmanova, Michael Doherty, Changfu Kuo, Jie Wei, Abhishek Abhishek, Christian Mallen, Chao Zeng, Yilun Wang, Guanghua Lei, Weiya Zhang(2020). Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study . Rheumatology. 59. (10). p. 2898--2907. Oxford University Press ({OUP})

Aliya Sarmanova, Subhashisa Swain, Carol Coupland, Michael Doherty, Weiya Zhang(2020). Comorbidities in Osteoarthritis: A Systematic Review and Meta‐Analysis of Observational Studies . Arthritis Care & Research. Wiley

Aliya Sarmanova, S Swain, C Mallen, C F Kuo, C Coupland, M Doherty, W Zhang(2020). Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD) . Osteoarthritis and Cartilage. W.B. Saunders

Aliya Sarmanova, Michael Doherty, Changfu Kuo, et al.(2020). Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study . Rheumatology. Oxford University Press

Aliya Sarmanova, K. Akin-Akinyosoye, G. S. Fernandes, N. Frowd, L. Swaithes, J. Stocks, A. Valdes, D. F. McWilliams, W. Zhang, M. Doherty, et al.(2020). Baseline self-report 'central mechanisms' trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort . Osteoarthritis and Cartilage. 28. (2). p. 173--181. W.B. Saunders

(2019). Comorbidities in Osteoarthritis: A systematic review and meta-analysis of observational studies . Arthritis care & research.

Aliya Sarmanova, Michelle Hall, Gwen S Fernandes, Ana M Valdes, David A Walsh, Michael Doherty, Weiya Zhang(2018). Thresholds of ultrasound synovial abnormalities for knee osteoarthritis - a cross sectional study in the general population . Osteoarthritis and Cartilage. W.B. Saunders

Aliya Sarmanova, Gwen Sascha Fernandes, H Richardson, A M Valdes, David Andrew Walsh, Weiya Zhang, Michael Doherty(2018). Contribution of central and peripheral risk factors to prevalence . Osteoarthritis and Cartilage. 26. (11). p. 1461--1473. W.B. Saunders

Aliya Sarmanova, Monica S M Persson, Michael Doherty, Weiya Zhang(2018). Comment on: Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials: reply . Rheumatology. 57. (11). p. 2060--2061. Oxford University Press

Aliya Sarmanova, Monica S M Persson, Michael Doherty, Weiya Zhang(2018). Comment on: Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials: reply . Rheumatology. Oxford University Press ({OUP})

A. Sarmanova, G.S. Fernandes, H. Richardson, A.M. Valdes, D.A. Walsh, W. Zhang, M. Doherty(2018). Contribution of central and peripheral risk factors to prevalence, incidence and progression of knee pain: a community-based cohort study . Osteoarthritis and Cartilage. 26. (11). p. 1461--1473. Elsevier {BV}

Aliya Sarmanova, Michael Doherty, Wendy Jenkins, Helen Richardson, Abhishek Abhishek, Deborah Ashton, Christine Barclay, Sally Doherty, Lelia Duley, Rachael Hatton, et al.(2018). Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial . Lancet. 392. (10156). p. 1403--1412. Lancet Publishing Group

Aliya Sarmanova, Monica S M Persson, Michael Doherty, Weiya Zhang(2018). Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials . Rheumatology. 57. (10). p. 1830--1837. Oxford University Press

Aliya Sarmanova, Monica S M Persson, Michael Doherty, Weiya Zhang(2018). Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials . Rheumatology. 57. (10). p. 1830--1837. Oxford University Press ({OUP})

Aliya Sarmanova, Nicola Whiteside, Xi Chen, Kun Zou, Natasya Abdullah, Michael Doherty, Weiya Zhang(2018). Proportion of contextual effects in the treatment of fibromyalgia—a meta-analysis of randomised controlled trials . Clinical Rheumatology. 37. (5). p. 1375--1382. Springer London

Aliya Sarmanova, Chao Zeng, Jie Wei, Monica S M Persson, Michael Doherty, Dongxing Xie, YiLun Wang, Xiaoxiao Li, Jiatian Li, Huizhong Long, et al.(2018). Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies . British Journal of Sports Medicine. 52. (10). p. 642--650. BMJ Publishing Group

Zeng C, Wei J, Persson MSM, Sarmanova A, Doherty M, Xie D, Wang Y, Li X, Li J, Long H, et al.(2018). Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies . British journal of sports medicine.

Aliya Sarmanova, Michelle Hall, Gwen S. Fernandes, Archan Bhattacharya, Ana M. Valdes, David A. Walsh, Michael Doherty, Weiya Zhang(2017). Association between ultrasound-detected synovitis and knee pain: A population-based case-control study with both cross-sectional and follow-up data . Arthritis Research and Therapy. 19. (1). BioMed Central

Whiteside N, Sarmanova A, Chen X, Zou K, Abdullah N, Doherty M, Zhang W(2017). Proportion of contextual effects in the treatment of fibromyalgia-a meta-analysis of randomised controlled trials . Clinical rheumatology.

Sarmanova A, Hall M, Fernandes GS, Bhattacharya A, Valdes AM, Walsh DA, Doherty M, Zhang W(2017). Association between ultrasound-detected synovitis and knee pain: a population-based case-control study with both cross-sectional and follow-up data . Arthritis research & therapy.

Aliya Sarmanova, G S Fernandes, S Warner, H Harvey, K Akin-Akinyosoye, H Richardson, N Frowd, L Marshall, J Stocks, M Hall, et al.(2017). Knee pain and related health in the community study (KPIC): A cohort study protocol . BMC Musculoskeletal Disorders. 18. BioMed Central

Fernandes GS, Sarmanova A, Warner S, Harvey H, Akin-Akinyosoye K, Richardson H, Frowd N, Marshall L, Stocks J, Hall M, et al.(2017). Knee pain and related health in the community study (KPIC): a cohort study protocol . BMC musculoskeletal disorders.

Aliya Sarmanova, Xi Chen, Kun Zou, Natasya Abdullah, Nicola Whiteside, Michael Doherty, Weiya Zhang(2017). The placebo effect and its determinants in fibromyalgia: meta-analysis of randomised controlled trials . Clinical Rheumatology. 36. (7). p. 1623--1630. Springer London

Chen X, Zou K, Abdullah N, Whiteside N, Sarmanova A, Doherty M, Zhang W(2017). The placebo effect and its determinants in fibromyalgia: meta-analysis of randomised controlled trials . Clinical rheumatology.

A. Sarmanova, M. Hall, J. Moses, M. Doherty, W. Zhang(2016). Synovial changes detected by ultrasound in people with knee osteoarthritis – a meta-analysis of observational studies . Osteoarthritis and Cartilage. 24. (8). p. 1376--1383. Elsevier {BV}

Aliya Sarmanova, Michelle Hall, J Moses, Michael University of Nottingham, W Zhang(2016). Synovial changes detected by ultrasound in people with knee osteoarthritis - a meta-analysis of observational studies . Osteoarthritis and Cartilage. 24. (8). p. 1376--1383. W.B. Saunders