Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 250 /hr

★★★★★

☆☆☆☆☆

Hire Dr. William D.

United States

USD 250 /hr

Biomedical Health Scientist | Expertise in Infectious & Inflammatory Diseases, Human Microbiome and Nutrition

Profile Summary

I have spent my scientific career straddling both the academic and public arenas. Not only making sure that my research was solid, reproducible and clinically relevant but that scientifically accurate information reached the public. I have leveraged my scientific expertise, passion for science with my outgoing and extroverted personality to collaborate with news and media agencies to educate the public about different aspects of biomedical research and its impact on human health. Whether it is working with Buzzfeed to produce a series of videos illustrating that microbes are all around us (especially your cell phone), lending scientific expertise to viral outbreaks in Yosemite on the Today show, participating in podcasts, or speaking at large town hall-style forums or small private functions about probiotics and the human microbiome, I am able to deliver complex scientific material in a way that is understandable and fun but doesn't lose its accuracy or importance. Areas of expertise: human microbiome, infectious and inflammatory diseases, nutrition and mucosal immunology 20 years of continuous NIH funding, and several high profile publications and discoveries Please check out my LinkedIn profile for further details: http://www.linkedin.com/in/williamdepaolo/

Subject Matter Expertise

• ★ Microbiome Research
• ☆ Data Analysis
• ☆ Bioinformatics
• ☆ Food Science
• ☆ Nutrition Science
• ☆ Infectious Disease
• ☆ Cancer Research
• ☆ Metabolism & Metabolic Disease

Services

• Writing
• Product Development

Writing Clinical Trial Documentation, Technical Writing, Newswriting

Product Development Formulation

Work Experience

Associate Professor of Medicine and Endowed Chair in Gastroenterology

University of Washington

October 2016 - Present

Assistant Professor

Keck Hospital of USC

April 2011 - October 2016

Research Assistant Professor

University of Chicago

June 2007 - March 2011

Postdoctoral Fellow

University of Chicago

June 2004 - May 2007

Education

PhD (Immunology & Microbial Pathogenesis)

Northwestern University Feinberg School of Medicine

August 1999 - April 2004

Bachelor Science (Neuroscience)

Bates College

August 1995 - May 1999

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Okazaki S, Loupakis F, Stintzing S, Cao S, Zhang W, Yang D, Ning Y, Sunakawa Y, Stremitzer S, Matsusaka S, Berger MD. Clinical significance of TLR1 I602S polymorphism for patients with metastatic colorectal cancer treated with FOLFIRI plus bevacizumab. Molecular cancer therapeutics. 2016 Jul 1;15(7):1740-5.

Kamdar, K., Khakpour, S., Chen, J., Leone, V., Brulc, J., Mangatu, T., Antonopoulos, D.A., Chang, E.B., Kahn, S.A., Kirschner, B.S., et al.(2016). Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory Disease . Cell Host and Microbe. 19. (1). p. 21-31.

Nguyen, V., Pearson, K., Kim, J.-H., Kamdar, K., DePaolo, R.W.(2015). Retinoic acid can exacerbate T cell intrinsic TLR2 activation to promote tolerance . PLoS ONE. 10. (3).

Michail, S., Bultron, G., Depaolo, R.W.(2013). Genetic variants associated with Crohn's disease . Application of Clinical Genetics. 6. p. 25-32.

Kamdar, K., Nguyen, V., DePaolo, R.W.(2013). Toll-like receptor signaling and regulation of intestinal immunity . Virulence. 4. (3). p. 207-212.

Sugiura, Y., Kamdar, K., Khakpour, S., Young, G., Karpus, W.J., DePaolo, R.W.(2013). TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica . Mucosal Immunology. 6. (6). p. 1101-1109.

Depaolo, R.W., Abadie, V., Tang, F., Fehlner-Peach, H., Hall, J.A., Wang, W., Marietta, E.V., Kasarda, D.D., Waldmann, T.A., Murray, J.A., et al.(2011). Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens . Nature. 471. (7337). p. 220-225.

Elhofy, A., DePaolo, R.W., Lira, S.A., Lukacs, N.W., Karpus, W.J.(2009). Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis . Journal of Neuroimmunology. 213. (1-2). p. 91-99.

DePaolo, R.W., Tang, F., Kim, I., Han, M., Levin, N., Ciletti, N., Lin, A., Anderson, D., Schneewind, O., Jabri, B.(2008). Toll-Like Receptor 6 Drives Differentiation of Tolerogenic Dendritic Cells and Contributes to LcrV-Mediated Plague Pathogenesis . Cell Host and Microbe. 4. (4). p. 350-361.

DeBord, K.L., Anderson, D.M., Marketon, M.M., Overheim, K.A., DePaolo, R.W., Ciletti, N.A., Jabri, B., Schneewind, O.(2006). Immunogenicity and protective immunity against bubonic plague and pneumonic plague by immunization of mice with the recombinant V10 antigen, a variant of LcrV . Infection and Immunity. 74. (8). p. 4910-4914.

Overheim, K.A., DePaolo, R.W., Debord, K.L., Morrin, E.M., Anderson, D.M., Green, N.M., Brubaker, R.R., Jabri, B., Schneewind, O.(2005). LcrV plague vaccine with altered immunomodulatory properties . Infection and Immunity. 73. (8). p. 5152-5159.

DePaolo, R.W., Lathan, R., Rollins, B.J., Karpus, W.J.(2005). The chemokine CCL2 is required for control of murine gastric Salmonella enterica infection . Infection and Immunity. 73. (10). p. 6514-6522.

Marketon, M.M., DePaolo, R.W., DeBord, K.L., Jabri, B., Schneewind, O.(2005). Microbiology: Plague bacteria target immune cells during infection . Science. 309. (5741). p. 1739-1741.

DePaolo, R.W., Lathan, R., Karpus, W.J.(2004). CCR5 regulates high dose oral tolerance by modulating CC chemokine ligand 2 levels in the GALT . Journal of Immunology. 173. (1). p. 314-320.

DePaolo, R.W., Rollins, B.J., Kuziel, W., Karpus, W.J.(2003). CC chemokine ligand 2 and its receptor regulate mucosal production of IL-12 and TGF-β in high dose oral tolerance . Journal of Immunology. 171. (7). p. 3560-3567.