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Hire Nicholas P.

United Kingdom

USD 80 /hr

Experienced statistician, with over 8 years experience in clincial research.

Profile Summary

8+ years experience of clinical trial design, analysis and dissemination. Experienced in R, including Shiny apps for data visulisation. Experience across phase I, II, III, IV studies, in many different therapeutic areas. Authored SAPs, protocols, CSRs, and sample size calculations. Coded ADAMs and STDMs in R. Knowledge across all statistical methods.

Subject Matter Expertise

• ☆ Biostatistics
• ☆ Statistics
• ☆ Statistical Theory
• ☆ Applied Statistics
• ☆ Comparative Analysis
• ☆ Social Statistics
• ☆ Meta-Analysis
• ☆ Regression Analysis
• ☆ Multivariate Analysis
• ☆ Nonlinear Regression
• ☆ Bayesian Statistics
• ☆ Correlation Analysis
• ☆ Statistical Computing
• ☆ Mathematical Statistics
• ☆ Survey Design
• ☆ Study Design
• ☆ Statistical Review
• ☆ Spatial Statistics
• ☆ Medical Statistics
• ☆ Health Data Analysis
• ☆ Trend Analysis
• ☆ R
• ☆ Research Methodology
• ☆ Survey Design & Methodology

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Non-Medical Regulatory Writing, Technical Writing

Research Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Healthcare Consulting, Scientific and Technical Consulting, Regulatory Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Analysis, Data Visualization, Big Data Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

Product Development Quality Assurance & Control (QA/QC)

Work Experience

University of Oxford

- Present

Biostatistician

Lindus Health

November 2024 - Present

Education

MSc in Statistics (SMSAS)

University of Kent

September 2017 - August 2018

BSc. Physics

University of Leicester

September 2012 - August 2015

Certifications

• MSc. Statistics

  University of Kent

  September 2018 - Present

Publications

JOURNAL ARTICLE

Nicholas Peckham, Jonathan A Cook, Piers Patten, Paul Moss, Abhishek Abhishek, Vicki S Barber, Anne Francis, Lelia Duley, Robbert Hoogeboom, Brian J Willett, et al. (2025). The impact of pausing Bruton Tyrosine Kinase inhibitor (BTKi) therapy versus continued therapy on vaccination immune response in patients with chronic lymphocytic leukaemia: the IMPROVE RCT . Efficacy and Mechanism Evaluation.

Nicholas Peckham, Abhishek Abhishek, Corinna Pade, Joseph M Gibbons, Lucy Cureton, Catherine J Reynolds, Anne Francis, Vicki Barber, Jennifer Williams, Duncan Appelbe, et al. (2025). Temporary 2-week suspension of methotrexate treatment to enhance COVID-19 vaccine response in people with immune-mediated inflammatory diseases: the VROOM RCT . Efficacy and Mechanism Evaluation.

Nicholas Peckham, Abhishek Abhishek, Corinna Pade, Joseph M Gibbons, Lucy Cureton, Catherine J Reynolds, Anne Francis, Vicki Barber, Jennifer Williams, Duncan Appelbe, et al. (2025). Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial . Efficacy and Mechanism Evaluation.

Nicholas Peckham, Abhishek Abhishek, Corinna Pade, Joseph M Gibbons, Lucy Cureton, Catherine J Reynolds, Anne Francis, Vicki Barber, Jennifer Williams, Duncan Appelbe, et al. (2025). Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial . Efficacy and Mechanism Evaluation.

Nicholas Peckham, Abhishek Abhishek, Corinna Pade, Joseph M Gibbons, Lucy Cureton, Catherine J Reynolds, Anne Francis, Vicki Barber, Jennifer Williams, Duncan Appelbe, et al. (2025). Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study) . Efficacy and Mechanism Evaluation.

Achten J, Appelbe D, Spoors L, Peckham N, Kandiyali R, Mason J, Ferguson D, Wright J, Wilson N, Preston J, et al.(2024). Protocol for Surgery or Cast of the EpicoNdyle in Children's Elbows (SCIENCE) . Bone & joint open.

Achten, J., Appelbe, D., Spoors, L., Peckham, N., Kandiyali, R., Mason, J., Ferguson, D., Wright, J., Wilson, N., Preston, J., et al.(2024). Protocol for Surgery or Cast of the EpicoNdyle in Children’s Elbows (SCIENCE) a multicentre prospective randomized superiority trial of operative fixation versus non-operative treatment for medial epicondyle fractures of the humerus in children . Bone and Joint Open. 5. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 69-77.

Cutteridge, J., Dixon, J., Garrido, P., Peckham, N., Smith, C., Woods, A., Gwilym, S.(2024). A systematic review and meta-analysis of operative versus non-operative management for first time traumatic anterior shoulder dislocation in young adults . Shoulder and Elbow.

Bretherton, C.P., Achten, J., Jogarah, V., Petrou, S., Peckham, N., Achana, F., Appelbe, D., Kearney, R., Claireux, H., Bell, P., et al.(2024). Early versus delayed weight-bearing following operatively treated ankle fracture (WAX): a non-inferiority, multicentre, randomised controlled trial . The Lancet. 403. (10446). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2787-2797.

Keene, D.J., Achten, J., Forde, C., Png, M.E., Grant, R., Draper, K., Appelbe, D., Tutton, E., Peckham, N., Dutton, S.J., et al.(2024). Effectiveness of supervised versus self-directed rehabilitation for adults aged 50 years and over with ankle fractures: protocol for the AFTER trial . Bone and Joint Open. 5. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 499-513.

Woods, A., Howard, A., Peckham, N., Rombach, I., Saleh, A., Achten, J., Appelbe, D., Thamattore, P., Gwilym, S.E.(2024). Randomized feasibility study of an autologous protein solution versus corticosteroids injection for treating subacromial pain in the primary care setting – the SPiRIT trial . Bone and Joint Open. 5. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 534-542.

Abhishek, A., Peckham, N., Pade, C., Gibbons, J.M., Cureton, L., Francis, A., Barber, V., Williams, J.A.E., Appelbe, D., Eldridge, L., et al.(2024). Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial . The Lancet Rheumatology. 6. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e92-e104.

Abhishek A, Peckham N, Pade C, Gibbons JM, Cureton L, Francis A, Barber V, Williams JAE, Appelbe D, Eldridge L, et al.(2023). Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial . The Lancet. Rheumatology.

Nicholas Peckham, May Ee Png, Matt Costa, Agni Nickil, Juul Achten, Mike R. Reed (2023). Cost-utility analysis of dual-antibiotic cement versus single-antibiotic cement for the treatment of displaced intracapsular hip fractures in older adults . The Bone & Joint Journal.

Barber VS, Peckham N, Duley L, Francis A, Abhishek A, Moss P, Cook JA, Parry HM(2023). Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia . BMJ open.

Nicholas Peckham, Nickil R Agni, Matthew L Costa, Juul Achten, Susan J Dutton, May Ee Png, Mike R Reed(2023). High-dose dual-antibiotic loaded cement for hip hemiarthroplasty in the UK (WHiTE 8): a randomised controlled trial . The Lancet. Elsevier {BV}

Barber, V.S., Peckham, N., Duley, L., Francis, A., Abhishek, A., Moss, P., Cook, J.A., Parry, H.M.(2023). Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia . BMJ Open. 13. (9).

Png, M.E., Costa, M., Nickil, A., Achten, J., Peckham, N., Reed, M.R.(2023). Cost-utility analysis of dual-antibiotic cement versus single-antibiotic cement for the treatment of displaced intracapsular hip fractures in older adults THE WHITE-8 TRIAL . Bone and Joint Journal. 105 B. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1070-1077.

Agni, N.R., Costa, M.L., Achten, J., Peckham, N., Dutton, S.J., Png, M.E., Reed, M.R.(2023). High-dose dual-antibiotic loaded cement for hip hemiarthroplasty in the UK (WHiTE 8): a randomised controlled trial . The Lancet. 402. (10397). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 196-202.

Keene DJ, Costa ML, Peckham N, Tutton E, Barber VS, Dutton SJ, Hopewell S, Redmond AC, Willett K, Lamb SE, et al.(2022). Progressive exercise versus best practice advice for adults aged 50 years or over after ankle fracture: the AFTER pilot randomised controlled trial . BMJ open.

Abhishek Abhishek, Rosemary J Boyton, Áine McKnight, Laura C Coates, James Bluett, Vicki Barber, Lucy Cureton, Anne Francis, Duncan Appelbe, et al., Nicholas Peckham(2022). Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial . The Lancet Respiratory Medicine. 10. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 840--850. Elsevier {BV}

Speich B, Odutayo A, Peckham N, Ooms A, Stokes JR, Saccilotto R, Gryaznov D, von Niederhäusern B, Copsey B, Altman DG, et al.(2022). A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study . Trials.

Abhishek A, Boyton RJ, McKnight Á, Coates L, Bluett J, Barber VS, Cureton L, Francis A, Appelbe D, Eldridge L, et al.(2022). Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study) . BMJ open.

Pallikadavath S, Vali Z, Patel R, Mavilakandy A, Peckham N, Clegg M, Sandilands AJ, Ng GA(2022). The Influence of Environmental Air Pollution on Ventricular Arrhythmias: A Scoping Review . Current cardiology reviews.

Pallikadavath, S., Vali, Z., Patel, R., Mavilakandy, A., Peckham, N., Clegg, M., Sandilands, A.J., Ng, G.A.(2022). The Influence of Environmental Air Pollution on Ventricular Arrhythmias: A Scoping Review . Current Cardiology Reviews. 18. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 28-41.

Speich, B., Odutayo, A., Peckham, N., Ooms, A., Stokes, J.R., Saccilotto, R., Gryaznov, D., von Niederhäusern, B., Copsey, B., Altman, D.G., et al.(2022). A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study . Trials. 23. (1).

Abhishek, A., Boyton, R.J., Peckham, N., McKnight, Á., Coates, L.C., Bluett, J., Barber, V., Cureton, L., Francis, A., Appelbe, D., et al.(2022). Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial . The Lancet Respiratory Medicine. 10. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 840-850.

Abhishek, A., Boyton, R.J., McKnight, Á., Coates, L., Bluett, J., Barber, V.S., Cureton, L., Francis, A., Appelbe, D., Eldridge, L., et al.(2022). Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study) . BMJ Open. 12. (5).

Glyn-Jones, S., Javaid, M.K., Beard, D., Newton, J., Kerslake, R., McBryde, C., Board, T., Dutton, S.J., Dritsaki, M., Khanduja, V., et al.(2022). Assessing a 12-month course of oral alendronate for adults with avascular necrosis of the hip: MANTIS RCT with internal pilot . Health Technology Assessment. 26. (43).

Keene, D.J., Costa, M.L., Peckham, N., Tutton, E., Barber, V.S., Dutton, S.J., Hopewell, S., Redmond, A.C., Willett, K., Lamb, S.E.(2022). Progressive exercise versus best practice advice for adults aged 50 years or over after ankle fracture: the AFTER pilot randomised controlled trial . BMJ Open. 12. (11).

Nicholas Peckham, Alisdair R. MacLeod, Gil Serrancolí, Ines Rombach, Patrick Hourigan, Vipul I. Mandalia, Andrew D. Toms, Benjamin J. Fregly, Harinderjit S. Gill (2021). Personalised high tibial osteotomy has mechanical safety equivalent to generic device in a case–control in silico clinical trial . Communications Medicine.

Agni NR, Costa ML, Achten J, O'Connor H, Png ME, Peckham N, Dutton SJ, Wallis S, Milca S, Reed M(2021). A randomized clinical trial of low dose single antibiotic-loaded cement versus high dose dual antibiotic-loaded cement in patients receiving a hip hemiarthroplasty after fracture: A protocol for the WHiTE 8 COPAL study . Bone & joint open.

Agni, N.R., Costa, M.L., Achten, J., O’connor, H., Png, M.E., Peckham, N., Dutton, S.J., Wallis, S., Milca, S., Reed, M.(2021). A randomized clinical trial of low dose single antibiotic-loaded cement versus high dose dual antibiotic-loaded cement in patients receiving a hip hemiarthroplasty after fracture: A protocol for the WHiTE 8 COPAL study . Bone and Joint Open. 2. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 72-78.

MacLeod, A.R., Peckham, N., Serrancolí, G., Rombach, I., Hourigan, P., Mandalia, V.I., Toms, A.D., Fregly, B.J., Gill, H.S.(2021). Personalised high tibial osteotomy has mechanical safety equivalent to generic device in a case–control in silico clinical trial . Communications Medicine. 1. (1).

Mellor, K., Eddy, S., Peckham, N., Bond, C.M., Campbell, M.J., Lancaster, G.A., Thabane, L., Eldridge, S.M., Dutton, S.J., Hopewell, S.(2021). Progression from external pilot to definitive randomised controlled trial: A methodological review of progression criteria reporting . BMJ Open. 11. (6).

Bretherton, C.P., Claireaux, H.A., Achten, J., Athwal, A., Dutton, S.J., Peckham, N., Petrou, S., Kearney, R.S., Appelbe, D., Griffin, X.L.(2021). Protocol for the Weight-bearing in Ankle Fractures (WAX) trial: a multicentre prospective non-inferiority trial of early versus delayed weight-bearing after operatively managed ankle fracture . BMC Musculoskeletal Disorders. 22. (1).

Patel, R., Kemp, C.L., Hafejee, M., Peckham, N., Jain, V., McCann, G.P., Pallikadavath, S.(2021). The Underrepresentation of Females in Studies Assessing the Impact of High-Dose Exercise on Cardiovascular Outcomes: a Scoping Review . Sports Medicine - Open. 7. (1).

Nicholas Peckham, Ines Rombach, Ruth Knight, Jamie R. Stokes, Jonathan A. Cook(2020). Current practice in analysing and reporting binary outcome data—a review of randomised controlled trial reports . BMC Medicine. 18. (1). Springer Science and Business Media {LLC}

Rombach, I., Rombach, I., Rombach, I., Knight, R., Knight, R., Knight, R., Peckham, N., Peckham, N., Peckham, N., Stokes, J.R., et al.(2020). Current practice in analysing and reporting binary outcome data - A review of randomised controlled trial reports . BMC Medicine. 18. (1).

Wade, D.T., Cooper, J., Peckham, N., Belci, M.(2020). Immunotherapy to reduce frequency of urinary tract infections in people with neurogenic bladder dysfunction; a pilot randomised, placebo-controlled trial . Clinical Rehabilitation. 34. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1458-1464.

BOOK

Glyn-Jones S, Javaid MK, Beard D, Newton J, Kerslake R, McBryde C, Board T, Dutton SJ, Dritsaki M, Khanduja V, et al.(2022). Assessing a 12-month course of oral alendronate for adults with avascular necrosis of the hip: MANTIS RCT with internal pilot . Health technology assessment (Winchester, England).

Bretherton, C. P., Claireaux, H. A., Achten, J., Athwal, A., Dutton, S. J., Peckham, N., Petrou, S., Kearney, R. S., Appelbe, D., Griffin, X. L.(2021). Protocol for the Weight-bearing in Ankle Fractures (WAX) trial: a multicentre prospective non-inferiority trial of early versus delayed weight-bearing after operatively managed ankle fracture . BMC musculoskeletal disorders. 22. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString Online-Ressource.