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Hire Dr. Nicholas M.

Canada

USD 30 /hr

Profile Summary

Born and raised in Toronto (Canada), I have developed a passion for interdisciplinary biomedical sciences, with interests ranging from biostatistics, machine learning, computational biology and meta-analytics to experimental research, cellular mechanobiology and skeletal physiology. I completed my PhD in 2019 at McGill University (Montreal, Canada), where I was involved in the discovery of novel mechanotransductive signalling pathways in bone, as-well as the development of meta-analytic methods for translational research. During my doctoral training, I was also heavily involved in teaching statistics and meta-analytic methods, which culminated in my development of a meta-analytics course at McGill University. Since completing my doctorate, I have consulted on various projects which have demanded domain expertise in the biomedical sciences and statistics. My current interests involve addressing current translational failures in clinical research, development of computational tools for meta-analytics (i.e., application of machine learning in evidence consolidation and synthesis) and understanding skeletal mechanobiology and related signalling processes (e.g., purinergics). I am always looking to expand my horizons and welcome creative and demanding opportunities.

Subject Matter Expertise

• ★ Meta-Analysis
• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Cell Signaling Pathways
• ☆ Stem Cell Research
• ☆ Microscopy
• ☆ Signal Processing
• ☆ Data Analysis
• ☆ Computer Simulation/Computational Modeling
• ☆ Machine Learning
• ☆ Text Mining & Analytics
• ☆ Bioinformatics
• ☆ Python
• ☆ Matlab
• ☆ Clinical Trials
• ☆ Connective Tissue
• ☆ Research
• ☆ Peer Review
• ☆ Data-Driven Decision Making

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Work Experience

Postdoctoral Researcher

University of Toronto

September 2019 - Present

Postdoctoral Researcher

McGill University

January 2019 - Present

Meta-analysis Instructor

McGill Summer Institute in Innovate Methodologies

2018 - Present

Statistics Teaching Assistant

McGill University

September 2016 - December 2018

Anatomy Teaching Assistant

McGill University

September 2014 - December 2014

Education

PhD, Quantitative Biological Sciences

McGill University

May 2015 - February 2019

B.Sc. (Anatomy and Cell Biology)

McGill University

September 2012 - February 2016

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Nicholas Mikolajewicz, Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Catherine Ross, Kevin R. Brown, et al.(2020). Functional genomic landscape of cancer-intrinsic evasion of killing by T cells . Nature. Springer Science and Business Media {LLC}

Nicholas Mikolajewicz, Nick Bishop, Andrew J Burghardt, Lars Folkestad, Anthony Hall, Kenneth M Kozloff, Pauline T Lukey, Michael Molloy‐Bland, Suzanne N Morin, Amaka C Offiah, et al.(2019). {HR}-{pQCT} Measures of Bone Microarchitecture Predict Fracture: Systematic Review and Meta-Analysis . Journal of Bone and Mineral Research. Wiley

Mikolajewicz N, Komarova SV(2019). Meta-Analytic Methodology for Basic Research: A Practical Guide . Frontiers in physiology.

(2019). Simultaneous Fluorescent Recordings of Extracellular ATP and Intracellular Calcium in Mammalian Cells . BIO-PROTOCOL.

Tiedemann K, Sadvakassova G, Mikolajewicz N, Juhas M, Sabirova Z, Tabariès S, Gettemans J, Siegel PM, Komarova SV(2018). Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis . Translational oncology.

Nicholas Mikolajewicz, Ali Mohammed, Martin Morris, Svetlana V. Komarova(2018). Meta-analysis of mechanically-stimulated {ATP} release from mammalian cells . Journal of Cell Science. p. jcs.223354. The Company of Biologists

Mikolajewicz, N., Zimmermann, E.A., Willie, B.M., Komarova, S.V.(2018). Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair . eLife. 7.

Mackay L, Mikolajewicz N, Komarova SV, Khadra A(2016). Systematic Characterization of Dynamic Parameters of Intracellular Calcium Signals . Frontiers in physiology.

DISSERTATION THESIS

(2019). Purinergic mechanotransduction in bone . McGill University.

OTHER

N. Mikolajewicz, S. Sehayek, P. W. Wiseman, S. V. Komarova(2018). Transmission of mechanical information by purinergic signaling . Cold Spring Harbor Laboratory