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Hire Bryan M.
United States
USD 40 /hr
Data analyst, writer, and editor with 10+ years' experience and over 50 publications in multiple life science and medical fields. Extensive grant-writing experience.
Profile Summary
Subject Matter Expertise
Services
Writing
Clinical Trial Documentation,
Technical Writing,
General Proofreading & Editing
Research
Fact Checking,
Scientific and Technical Research,
Systematic Literature Review,
Secondary Data Collection
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis,
Image Analysis,
Data Visualization,
Data Processing,
Data Insights
Product Development
Recipe Development
Work Experience
Data Scientist I
University of Kentucky
June 2022 - Present 
Research Analyst
Indiana University School of Medicine
April 2015 - Present
Owner, Writer, Data Analyst
Maloney Consulting
April 2010 - March 2015
Laboratory Coordinator
Texas A&M University Corpus Christi College of Science and Engineering
January 2013 - October 2014
Research Technician
Indiana University School of Medicine
October 2002 - April 2010
Education
Bachelors
Earlham College
September 1984 - December 1995
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Crossing the “Birth Border” for Epigenetic Effects <head>
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</head> . Biological Psychiatry.
Bryan Maloney, Ruizhi Wang, Nipun Chopra, Kwangsik Nho, Alexander G. Obukhov, Peter T. Nelson, Scott E. Counts, Debomoy K. Lahiri(2022). Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers . Molecular Psychiatry. Springer Science and Business Media {LLC}
Lahiri, D.K., Maloney, B., Song, W., Sokol, D.K.(2022). Crossing the “Birth Border” for Epigenetic Effects . Biological Psychiatry. 92. (4). p. e21-e23.
Wang, R., Chopra, N., Nho, K., Maloney, B., Obukhov, A.G., Nelson, P.T., Counts, S.E., Lahiri, D.K.(2022). Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers . Molecular Psychiatry. 27. (2). p. 1256-1273.
Bryan Maloney, Nipun Chopra, Ruizhi Wang, Kwangsik Nho, John S. Beck, Naemeh Pourshafie, Alexander Niculescu, Andrew J. Saykin, Carlo Rinaldi, Scott E. Counts, et al.(2021). MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties . Molecular Psychiatry. Springer Science and Business Media {LLC}
Bryan Maloney, Debomoy K. Lahiri, Ruizhi Wang, Deborah K. Sokol, Jack T. Rogers, Cara J. Westmark (2021). How autism and Alzheimer’s disease are TrAPPed . Molecular Psychiatry.
Lahiri, D.K., Maloney, B., Wang, R., Sokol, D.K., Rogers, J.T., Westmark, C.J.(2021). How autism and Alzheimer’s disease are TrAPPed . Molecular Psychiatry. 26. (1). p. 26-29.
Chopra, N., Wang, R., Maloney, B., Nho, K., Beck, J.S., Pourshafie, N., Niculescu, A., Saykin, A.J., Rinaldi, C., Counts, S.E., et al.(2021). MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties . Molecular Psychiatry. 26. (10). p. 5636-5657.
Lahiri, D.K., Maloney, B., Greig, N.H.(2021). Preface . Current Aging Science. 14. (1). p. 1-2.
Perez, F.P., Maloney, B., Chopra, N., Morisaki, J.J., Lahiri, D.K.(2021). Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures . Scientific Reports. 11. (1).
Correction: Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer’s disease <head>
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</head> . Translational Psychiatry.
Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer’s disease <head>
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</head> . Translational Psychiatry.
Ray, B., Maloney, B., Sambamurti, K., Karnati, H.K., Nelson, P.T., Greig, N.H., Lahiri, D.K.(2020). Correction: Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer’s disease (Translational Psychiatry, (2020), 10, 1, (47), 10.1038/s41398-020-0709-x) . Translational Psychiatry. 10. (1).
Westmark, C.J., Maloney, B., Alisch, R.S., Sokol, D.K., Lahiri, D.K.(2020). FMRP Regulates the Nuclear Export of Adam9 and Psen1 mRNAs: Secondary Analysis of an N <sup>6</sup>-Methyladenosine Dataset . Scientific Reports. 10. (1).
Ray, B., Maloney, B., Sambamurti, K., Karnati, H.K., Nelson, P.T., Greig, N.H., Lahiri, D.K.(2020). Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer’s disease . Translational Psychiatry. 10. (1).
Bryan Maloney, Yokesh Balaraman, Yunlong Liu, Nipun Chopra, Howard J. Edenberg, John Kelsoe, John I. Nurnberger, Debomoy K. Lahiri (2019). Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer’s disease . Scientific Reports.
Bryan Maloney, Arpita Konar, Richa Gupta, Rajendra K. Shukla, Vinay K. Khanna, Renu Wadhwa, Debomoy K. Lahiri, Mahendra K. Thakur (2019). M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera . Scientific Reports.
Bryan Maloney, Justin M. Long, Jack T. Rogers, Debomoy K. Lahiri (2019). Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease . Molecular Psychiatry.
Konar, A., Gupta, R., Shukla, R.K., Maloney, B., Khanna, V.K., Wadhwa, R., Lahiri, D.K., Thakur, M.K.(2019). M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera . Scientific Reports. 9. (1).
Lahiri, D.K., Maloney, B., Wang, R.(2019). APPealing for a role in cellular iron efflux . Journal of Biological Chemistry. 294. (24). p. 9365.
Sokol, D.K., Maloney, B., Westmark, C.J., Lahiri, D.K.(2019). Novel contribution of secreted amyloid-β precursor protein to white matter brain enlargement in autism spectrum disorder . Frontiers in Psychiatry. 10. (APR).
Maloney, B., Balaraman, Y., Liu, Y., Chopra, N., Edenberg, H.J., Kelsoe, J., Nurnberger, J.I., Lahiri, D.K.(2019). Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer’s disease . Scientific Reports. 9. (1).
Long, J.M., Maloney, B., Rogers, J.T., Lahiri, D.K.(2019). Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease . Molecular Psychiatry. 24. (3). p. 345-363.
Bryan Maloney, Baindu L. Bayon, Nasser H. Zawia, Debomoy K. Lahiri(2018). Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis . NeuroToxicology. 68. p. 126--132. Elsevier {BV}
Bryan Maloney, Arpita Konar, Ashish Kumar, Debomoy K. Lahiri, Mahendra K. Thakur (2018). A serine protease KLK8 emerges as a regulator of regulators in memory: Microtubule protein dependent neuronal morphology and PKA-CREB signaling . Scientific Reports.
Maloney, B., Bayon, B.L., Zawia, N.H., Lahiri, D.K.(2018). Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis . NeuroToxicology. 68. p. 126-132.
Konar, A., Kumar, A., Maloney, B., Lahiri, D.K., Thakur, M.K.(2018). A serine protease KLK8 emerges as a regulator of regulators in memory: Microtubule protein dependent neuronal morphology and PKA-CREB signaling . Scientific Reports. 8. (1).
Lahiri, D.K., Maloney, B., Greig, N.H.(2017). Are pulmonary fibrosis and Alzheimer’s disease linked? Shared dysregulation of two miRNA species and downstream pathways accompany both disorders . Journal of Biological Chemistry. 292. (49). p. 20353.
Lahiri, D.K., Maloney, B., Sambamurti, K.(2017). When figures and data contradict text: MiR346 is apparently reduced in breast cancer tissue, contrary to claims by a paper's author . Gene. 635. p. 46-47.
Lahiri, D.K., Konar, A., Thakur, M.K., Maloney, B.(2017). A cardinal sin when researching neuropsin/KLK8: Thou shalt validate antibodies . Alzheimer's and Dementia. 13. (9). p. 1068-1069.
C J Westmark, D K Sokol, B Maloney, D K Lahiri(2016). Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism . Molecular Psychiatry. 21. (10). p. 1333--1341. Springer Science and Business Media {LLC}
(2016). Epigenetics of dementia: understanding the disease as a transformation rather than a state . Lancet Neurology.
Maloney, B., Lahiri, D.K.(2016). Epigenetics of dementia: understanding the disease as a transformation rather than a state . The Lancet Neurology. 15. (7). p. 760-774.
Lahiri, D.K., Maloney, B., Bayon, B.L., Chopra, N., White, F.A., Greig, N.H., Nurnberger, J.I.(2016). Transgenerational latent early-life associated regulation unites environment and genetics across generations . Epigenomics. 8. (3). p. 373-387.
Ray, B., Sokol, D.K., Maloney, B., Lahiri, D.K.(2016). Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue . Scientific Reports. 6.
Westmark, C.J., Sokol, D.K., Maloney, B., Lahiri, D.K.(2016). Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism . Molecular Psychiatry. 21. (10). p. 1333-1341.
Bryan Maloney, Debomoy K. Lahiri, Justin Long, Nipun Chopra, Baindu L. Bayon, Nigel H. Greig, Kumar Sambamurti, John Spence, Balmiki Ray(2015). Does the mini-mental state examination (MMSE) measure a deeper biological process? modeling mmse score versus three selected mirna levels may reveal pathological roles in Alzheimer's disease progression . Alzheimer's & Dementia. 11. (7). p. P499--P500. Elsevier {BV}
(2014). Lessons from a BACE1 inhibitor trial: Off-site but not off base . Alzheimer's & Dementia.
Bryan Maloney, Craig A. Erickson, Balmiki Ray, Logan K. Wink, Katherine Bowers, Tori L. Schaefer, Christopher J. McDougle, Deborah K. Sokol, Debomoy K. Lahiri(2014). Impact of acamprosate on plasma amyloid-β precursor protein in youth: A pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker . Journal of Psychiatric Research. 59. p. 220--228. Elsevier {BV}
Erickson, C.A., Ray, B., Maloney, B., Wink, L.K., Bowers, K., Schaefer, T.L., McDougle, C.J., Sokol, D.K., Lahiri, D.K.(2014). Impact of acamprosate on plasma amyloid-β precursor protein in youth: A pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker . Journal of Psychiatric Research. 59. p. 220-228.
Perez, F.P., Bose, D., Maloney, B., Nho, K., Shah, K., Lahiri, D.K.(2014). Late-onset Alzheimer's disease, heating up and foxed by several proteins: Pathomolecular effects of the aging process . Journal of Alzheimer's Disease. 40. (1). p. 1-17.
Lahiri, Debomoy K. and Maloney, Bryan and Long, Justin M. and Greig, Nigel H.(2014). Lessons from a BACE1 inhibitor trial: Off-site but not off base . Alzheimerâs & Dementia. Elsevier BV
Lahiri, D.K., Maloney, B., Long, J.M., Greig, N.H.(2014). Lessons from a BACE1 inhibitor trial: Off-site but not off base . Alzheimer's and Dementia. 10. (5). p. S411-S419.
Maloney, Bryan, Ge, Yuan-Wen, Lahiri, Debomoy K., Rogers, Jack T.(2013). PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-beta precursor protein via a tissue-specific proximal regulatory element (PRE) . Bmc Genomics. 14.
Lahiri, D.K., Maloney, B., Rogers, J.T., Ge, Y.-W.(2013). PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE) . BMC Genomics. 14. (1).
Lahiri, Debomoy K. and Sokol, Deborah K. and Erickson, Craig and Ray, Balmiki and Ho, Chang Y. and Maloney, Bryan(2013). Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway . Frontiers in Cellular Neuroscience. 7. Frontiers Media SA
Lahiri, D.K., Sokol, D.K., Erickson, C., Ray, B., Ho, C.Y., Maloney, B.(2013). Autism as early neurodevelopmental disorder: Evidence for an sAPPamediated anabolic pathway . Frontiers in Cellular Neuroscience. (MAY).
Bryan Maloney, Syed Waseem Bihaqi, Axel Schumacher, Debomoy K. Lahiri, Nasser H. Zawia(2012). Do Epigenetic Pathways Initiate Late Onset Alzheimer Disease (LOAD): Towards a New Paradigm . CAR. 9. (5). p. 574--588. Bentham Science Publishers Ltd.
Bryan Maloney, Syed Waseem Bihaqi, Axel Schumacher, Debomoy K. Lahiri, Nasser H. Zawia(2012). Do Epigenetic Pathways Initiate Late Onset Alzheimer Disease (LOAD): Towards a New Paradigm . CAR. 9. (5). p. 574--588. Bentham Science Publishers Ltd.
Bihaqi, S.W., Schumacher, A., Maloney, B., Lahiri, D.K., Zawia, N.H.(2012). Do epigenetic pathways initiate late onset alzheimer disease (LOAD): Towards a new paradigm . Current Alzheimer Research. 9. (5). p. 574-588.
Maloney, B., Sambamurti, K., Zawia, N., Lahiri, D.K.(2012). Applying epigenetics to alzheimer's disease via the latent early-life associated regulation (LEARn) model . Current Alzheimer Research. 9. (5). p. 589-599.
Maloney, Bryan, Lahiri, Debomoy K.(2012). Gene x environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS) . Epigenomics. 4. (6). p. 685-699.
Lahiri, Debomoy K and Maloney, Bryan(2012). Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS) . Epigenomics. 4. (6). p. 685â??699. Future Medicine Ltd
Maloney, Bryan, Lahiri, Debomoy K.(2012). Structural and functional characterization of H2 haplotype MAPT promoter: Unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease . Gene. 501. (1). p. 63-78.
Maloney, B., Lahiri, D.K.(2012). Structural and functional characterization of H2 haplotype MAPT promoter: Unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease . Gene. 501. (1). p. 63-78.
Maloney, Bryan, Lahiri, Debomoy K.(2012). The "LEARn" (Latent Early-Life Associated Regulation) Model: An Epigenetic Pathway Linking Metabolic and Cognitive Disorders . Journal of Alzheimers Disease. 30. p. S15-S30.
Lahiri, D.K., Maloney, B.(2012). Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS) . Epigenomics. 4. (6). p. 685-699.
Lahiri, D.K., Maloney, B.(2012). The "lEARn" (latent early-life associated regulation) model: An epigenetic pathway linking metabolic and cognitive disorders . Journal of Alzheimer's Disease. 30. (SUPPL.2).
Mathew, L.G., Maloney, B., Takeda, N., Mason, H.S.(2011). Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants . Plant Molecular Biology. 75. (3). p. 263-275.
Sokol, D.K., Maloney, B., Long, J.M., Ray, B., Lahiri, D.K.(2011). Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links . Neurology. 76. (15). p. 1344-1352.
Bailey, J.A., Maloney, B., Ge, Y.-W., Lahiri, D.K.(2011). Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis . Gene. 488. (1-2). p. 13-22.
Maloney, Bryan, Mason, Hugh S., Mathew, Lolita G., Takeda, Naokazu(2011). Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants . Plant Molecular Biology. 75. (3). p. 263-275.
Maloney, Bryan, Bailey, Jason A., Ge, Yuan-Wen, Lahiri, Debomoy K.(2011). Functional activity of the novel Alzheimer's amyloid beta-peptide interacting domain (A beta ID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis . Gene. 488. (1-2). p. 13-22.
Maloney, Bryan, Lahiri, Debomoy K.(2011). The Alzheimer's amyloid beta-peptide (A beta) binds a specific DNA A beta-interacting domain (A beta ID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: Characterizing a new regulatory motif . Gene. 488. (1-2). p. 1-12.
Maloney, B., Lahiri, D.K.(2011). The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: Characterizing a new regulatory motif . Gene. 488. (1-2). p. 1-12.
Maloney, B., Ge, Y.-W., Petersen, R.C., Hardy, J., Rogers, J.T., Pérez-Tur, J., Lahiri, D.K.(2010). Functional characterization of three single-nucleotide polymorphisms present in the human APOε promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions . American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153. (1). p. 185-201.
Lahiri, D.K., Maloney, B.(2010). The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps . Experimental Gerontology. 45. (4). p. 291-296.
Maloney, Bryan, Ge, Yuan-Wen, Hardy, John, Lahiri, Debomoy K., Perez-Tur, Jordi, Petersen, Ronald C., Rogers, Jack T.(2010). Functional Characterization of Three Single-Nucleotide Polymorphisms Present in the Human APOE Promoter Sequence: Differential Effects in Neuronal Cells and on DNA-Protein Interactions . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 153B. (1). p. 185-201.
Maloney, Bryan, Lahiri, Debomoy K.(2010). Beyond the signaling effect role of amyloid-beta(42) on the processing of APP, and its clinical implications . Experimental Neurology. 225. (1). p. 51-54.
Lahiri, D.K., Maloney, B.(2010). Beyond the signaling effect role of amyloid-β<sub>42</sub> on the processing of APP, and its clinical implications . Experimental Neurology. 225. (1). p. 51-54.
Maloney, Bryan, Lahiri, Debomoy K.(2010). The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps . Experimental Gerontology. 45. (4). p. 291-296.
Jason A. Bailey, Bryan J. Maloney, Yuan-Wen Ge, Debomoy K. Lahiri(2009). Internalization of the amyloid beta (Aβ) peptide may result in binding to the regulatory region of the APP gene promoter . Alzheimer's & Dementia. 5. (4). p. P315--P316. Elsevier {BV}
Bryan Maloney, Balmiki Ray, Elizabeth P. Hayden, John I. Nurnberger, Debomoy K. Lahiri(2009). Development and validation of the high-quality ‘rapid method for swab’ to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism . Psychiatric Genetics. 19. (2). p. 72--82. Ovid Technologies (Wolters Kluwer Health)
Maloney, Bryan, Adwan, Lina, Basha, Md Riyaz, Dosunmu, Remi, Harry, G. Jean, Lahiri, Debomoy K., McPherson, Christopher A., Rice, Deborah C., Wu, Jinfang, Zawia, Nasser H.(2009). Lifespan Profiles of Alzheimer's Disease-Associated Genes and Products in Monkeys and Mice . Journal of Alzheimers Disease. 18. (1). p. 211-230.
Dosunmu, R., Wu, J., Adwan, L., Maloney, B., Basha, M.R., McPherson, C.A., Harry, G.J., Rice, D.C., Zawia, N.H., Lahiri, D.K.(2009). Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice . Journal of Alzheimer's Disease. 18. (1). p. 211-230.
Maloney, Bryan, Chen, DeMao, Lahiri, Debomoy K., Long, Justin, Sokol, Deborah K.(2009). Potential Alzheimer's Disease Markers for Autism? Beta-Amyloid Precursor Protein and Acetylcholinesterase Correlate with Aggression in Autism. Neurology. 72. (11). p. A53.
Bailey, J. A., Ge, Y. -W., Lahiri, D. K., Maloney, B.(2009). ROLE OF ALZHEIMER'S AMYLOID-BETA PEPTIDE AS A PUTATIVE TRANSCRIPTION FACTOR. Biopolymers. 92. (4). p. 354-355.
Lahiri, D. K., Maloney, B., Zawia, N. H.(2009). The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases . Molecular Psychiatry. 14. (11). p. 992-1003.
Lahiri, D.K., Maloney, B., Zawia, N.H.(2009). The LEARn model: An epigenetic explanation for idiopathic neurobiological diseases . Molecular Psychiatry. 14. (11). p. 992-1003.
Lahiri, Debomoy K. and Maloney, Bryan and Ray, Balmiki and Rogers, Jack T. and Zawia, Nasser(2009). The “LEARn” (Latent Early-life Associated Regulation) model may explain the etiology of sporadic cases of Alzheimer's disease . Alzheimerâs & Dementia. 5. (4). p. P146. Elsevier BV
Maloney, Bryan, Hayden, Elizabeth R., Lahiri, Debomoy K., Nurnberger, John I., Jr., Ray, Balmiki(2009). Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism . Psychiatric Genetics. 19. (2). p. 72-82.
Maloney, B., Ray, B., Hayden, E.R., Nurnberger Jr., J.I., Lahiri, D.K.(2009). Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter DOlvmorDhism . Psychiatric Genetics. 19. (2). p. 72-82.
Bryan Maloney, Debomoy K. Lahiri, Md. Riyaz Basha, DeMao Chen, Nasser Zawia(2008). P3-234: Early-life environment affects expression of genes invoved in Alzheimer's disease by an epigenetic mechanism . Alzheimer's & Dementia. 4. (4). p. T589. Elsevier BV
Maloney, Bryan, Greig, Nigel H., Lahiri, Debomoy K., Sambamurti, Kumar, Zawia, Nasser H.(2008). Early-life events may trigger biochemical pathways for Alzheimer's disease: the "LEARn" model . Biogerontology. 9. (6). p. 375-379.
Wu, J., Basha, Md.R., Brock, B., Cox, D.P., Cardozo-Pelaez, F., McPherson, C.A., Harry, J., Rice, D.C., Maloney, B., Chen, D., et al.(2008). Alzheimer's Disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): Evidence for a developmental origin and environmental link for AD . Journal of Neuroscience. 28. (1). p. 3-9.
Lahiri, D.K., Zawia, N.H., Greig, N.H., Sambamurti, K., Maloney, B.(2008). Early-life events may trigger biochemical pathways for Alzheimer's disease: The "LEARn" model . Biogerontology. 9. (6). p. 375-379.
Maloney, Bryan, Basha, Md. Riyaz, Brock, Brian, Cardozo-Pelaez, Fernando, Chen, Demao, Cox, David P., Harry, Jean, Lahiri, Debomoy K., McPherson, Christopher A., Rice, Deborah C., et al.(2008). Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (pb): Evidence for a developmental origin and environmental link for AD . Journal of Neuroscience. 28. (1). p. 3-9.
Maloney, Bryan, Anderson, Amy, Basha, Riyaz, Brock, Brian, DiPalma, Katie, Harry, G. Jean, Lahiri, Debomoy K., Rice, Deborah C., Zawia, Nasser H.(2008). Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis. Journal of Alzheimers Disease. 13. (1). p. 71-80.
Brock, B., Basha, R., DiPalma, K., Anderson, A., Harry, G.J., Rice, D.C., Maloney, B., Lahiri, D.K., Zawia, N.H.(2008). Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis . Journal of Alzheimer's Disease. 13. (1). p. 71-80.
Maloney, Bryan, Anderson, Amy, Basha, Riyaz, Brock, Brian, DiPalma, Katie, Harry, G. Jean, Lahiri, Debomoy K., Rice, Deborah C., Zawia, Nasser H.(2008). Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis. Journal of Alzheimers Disease. 13. (1). p. 71-80.
Maloney, Bryan, Dougherty, Lea R., Durbin, C. Emily, Hayden, Elizabeth P., Klein, Daniel N., Lahiri, Debomoy K., Nurnberger, John I., Jr., Olino, Thomas M., Sheikh, Haroon(2008). Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism . Journal of Affective Disorders. 107. (1-3). p. 227-230.
Hayden, E.P., Dougherty, L.R., Maloney, B., Olino, T.M., Sheikh, H., Durbin, C.E., Nurnberger Jr., J.I., Lahiri, D.K., Klein, D.N.(2008). Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism . Journal of Affective Disorders. 107. (1-3). p. 227-230.
Maloney, Bryan, Bailey, Jason, Duff, Karen, Figueroa, Helen, Herman, Mathieu, Krishnamurthy, Pavan, Lahiri, Debomoy K., Lau, Lit-Fui, Liu, Li, Ma, Junrong, et al.(2008). Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing . Neuron. 57. (5). p. 680-690.
Wen, Y., Yu, W.H., Maloney, B., Bailey, J., Ma, J., Marié, I., Maurin, T., Wang, L., Figueroa, H., Herman, M., et al.(2008). Transcriptional Regulation of β-Secretase by p25/cdk5 Leads to Enhanced Amyloidogenic Processing . Neuron. 57. (5). p. 680-690.
Bryan Maloney, Elizabeth P. Hayden, Lea R. Dougherty, C. Emily Durbin, Thomas M. Olino, John I. Nurnberger, Debomoy K. Lahiri, Daniel N. Klein(2007). Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: a multimethod association study . Psychiatric Genetics. 17. (3). p. 135--142. Ovid Technologies (Wolters Kluwer Health)
Maloney, B., Ge, Y.-W., Alley, G.M., Lahiri, D.K.(2007). Important differences between human and mouse APOE gene promoters: Limitation of mouse APOE model in studying Alzheimer's disease . Journal of Neurochemistry. 103. (3). p. 1237-1257.
Hayden, E.P., Dougherty, L.R., Maloney, B., Emily Durbin, C., Olino, T.M., Nurnberger Jr., J.I., Lahiri, D.K., Klein, D.N.(2007). Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: A multimethod association study . Psychiatric Genetics. 17. (3). p. 135-142.
Maloney, Bryan, Dougherty, Lea R., Durbin, C. Emily, Hayden, Elizabeth P., Klein, Daniel N., Lahiri, Debomoy K., Nurnberger, John I., Jr., Olino, Thomas M.(2007). Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: a multimethod association study . Psychiatric Genetics. 17. (3). p. 135-142.
Maloney, Bryan, Alley, George M., Ge, Yuan-Wen, Lahiri, Debomoy K.(2007). Important differences between human and mouse APOE gene promoters: limitation of mouse APOE model in studying Alzheimer's disease . Journal of Neurochemistry. 103. (3). p. 1237-1257.
Maloney, Bryan, Basha, Md Riyaz, Ge, Yuan Wen, Lahiri, Debomoy K., Zawia, Nasser H.(2007). How and when environmental agents and dietary factors affect the course of Alzheimer's disease: The "LEARn" model (Latent Early-Life Associated Regulation) may explain the triggering of AD . Current Alzheimer Research. 4. (2). p. 219-228.
Lahiri, D.K., Chen, D., Maloney, B., Holloway, H.W., Yu, Q.-S., Utsuki, T., Giordano, T., Sambamurti, K., Greig, N.H.(2007). The experimental Alzheimer's Disease drug posiphen [(+)-phenserine] lowers amyloid-β peptide levels in cell culture and mice . Journal of Pharmacology and Experimental Therapeutics. 320. (1). p. 386-396.
Lahiri, D.K., Maloney, B., Basha, Md.R., Yuan, W.G., Zawia, N.H.(2007). How and when environmental agents and dietary factors affect the course of Alzheimer's disease: The "LEARn" model (Latent Early-Life Associated Regulation) may explain the triggering of AD . Current Alzheimer Research. 4. (2). p. 219-228.
Maloney, Bryan, Chen, DeMao, Giordano, Tony, Greig, Nigel H., Holloway, Harold W., Lahiri, Debomoy K., Sambamurti, Kumar, Utsuki, Tada, Yu, Qian-sheng(2007). The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice . Journal of Pharmacology and Experimental Therapeutics. 320. (1). p. 386-396.
Sokol, D.K., Chen, D., Farlow, M.R., Dunn, D.W., Maloney, B., Zimmer, J.A., Lahiri, D.K.(2006). High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression . Journal of Child Neurology. 21. (6). p. 444-449.
Ge, YW, Lahiri, DK, Maloney, B(2006). Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells . Journal of Molecular Neuroscience. 29. (1). p. 65-80.
Maloney, Bryan, Chen, Demao, Dunn, David W., Farlow, Martin R., Lahiri, Debomoy K., Sokol, Deborah K., Zimmer, Jennifer A.(2006). High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression . Journal of Child Neurology. 21. (6). p. 444-449.
Maloney, Bryan, Ge, Yuan-Wen, Greig, Nigel H., Lahiri, Debomoy K., Rogers, Jack T., Sambamurti, Kumar(2006). Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: Shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors . Current Alzheimer Research. 3. (5). p. 475-483.
Lahiri, D.K., Ge, Y.-W., Rogers, J.T., Sambamurti, K., Greig, N.H., Maloney, B.(2006). Taking down the unindicted co-conspirators of amyloid β- peptide-mediated neuronal death: Shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors . Current Alzheimer Research. 3. (5). p. 475-483.
Chen, D., Kardatzke, D., Lahiri, D., Maloney, B., Sokol, D.(2006). Role of two Alzheimer's disease protein markers: Amyloid precursor protein and acetyleholinesterase with aggression in autism . International Journal of Developmental Neuroscience. 24. p. 551.
Ge, YW, Lahiri, DK, Maloney, B(2006). BACE1 gene promoter is differentially regulated - Detection of a novel promoter region for its cell type-specific regulation . Journal of Molecular Neuroscience. 28. (2). p. 193-210.
Lahiri, Debomoy K. and Maloney, Bryan and Ge, Yuan-Wen(2006). BACE1 Gene Promoter is Differentially Regulated: Detection of a Novel Promoter Region for Its Cell Type-Specific Regulation . Journal of Molecular Neuroscience. 28. (2). p. 193â??210. Springer Science + Business Media
Ge, YW, Greig, NH, Lahiri, DK, Maloney, B(2006). Characterization of the human beta-secretase 2 (BACE2) 5 '-flanking region - Identification of a 268-bp region as the basal BACE2 promoter . Journal of Molecular Neuroscience. 29. (1). p. 81-99.
Lahiri, D.K., Maloney, B., Ge, Y.-W.(2006). BACE1 gene promoter is differentially regulated: Detection of a novel promoter region for its cell type-specific regulation . Journal of Molecular Neuroscience. 28. (2). p. 193-210.
Lahiri, D.K., Maloney, B.(2006). Genes are not our destiny: The somatic epitype bridges between the genotype and the phenotype . Nature Reviews Neuroscience. 7. (12).
Maloney, B., Ge, Y.-W., Greig, N.H., Lahiri, D.K.(2006). Characterization of the human β-secretase 2 (BACE2) 5′-flanking region: Identification of a 268-bp region as the basal BACE2 promoter . Journal of Molecular Neuroscience. 29. (1). p. 81-99.
Maloney, Bryan, Basha, Riyaz, Bolin, Celeste M., Cardozo-Pelaez, Fernando, Cox, David, Lahiri, Debomoy K., Zawia, Nasser H.(2006). Exposure to lead (Pb) and the developmental origin of oxidative DNA damage in the aging brain . Faseb Journal. 20. (2). p. 788-+.
Bryan Maloney, Yuan-Wen Ge, Nigel H. Greig, Debomoy K. Lahiri(2006). Characterization of the Human β-Secretase 2 (BACE2) 5\'-Flanking Region: Identification of a 268-bp Region as the Basal BACE2 Promoter . JMN. 29. (1). p. 81--100. Springer Science $\mathplus$ Business Media
Bolin, C.M., Basha, R., Cox, D., Zawia, N.H., Maloney, B., Lahiri, D.K., Cardozo-Pelaez, F.(2006). Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain . FASEB Journal. 20. (6). p. 788-790.
Lahiri, Debomoy K. and Maloney, Bryan and Ge, Yuan-Wen(2006). Functional Domains of the BACE1and BACE2 Promoters and Mechanisms of Transcriptional Suppression of the BACE2 Promoter in Normal Neuronal Cells . Journal of Molecular Neuroscience. 29. (1). p. 65â??80. Springer Science + Business Media
Lahiri, D.K., Maloney, B., Ge, Y.-W.(2006). Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells . Journal of Molecular Neuroscience. 29. (1). p. 65-80.
Lahiri, Debomoy K. and Maloney, Bryan(2006). Genes are not our destiny: the somatic epitype bridges between the genotype and the phenotype . Nat Rev Neurosci. 7. (12). Nature Publishing Group
Ami, Y, Arntzen, CJ, Li, TC, Maloney, BJ, Mason, HS, Miyamura, T, Suzaki, Y, Takeda, N(2005). Challenges in creating a vaccine to prevent hepatitis E . Vaccine. 23. (15). p. 1870-1874.
Maloney, B.J., Takeda, N., Suzaki, Y., Ami, Y., Li, T.C., Miyamura, T., Arntzen, C.J., Mason, H.S.(2005). Challenges in creating a vaccine to prevent hepatitis E . Vaccine. 23. (15 SPEC. ISS.). p. 1870-1874.
Lahiri, D.K., Ge, Y.-W., Maloney, B., Wavrant-De Vrièze, F., Hardy, J.(2005). Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease . Neurobiology of Aging. 26. (10). p. 1329-1341.
Huang, Z., Elkin, G., Maloney, B.J., Beuhner, N., Arntzen, C.J., Thanavala, Y., Mason, H.S.(2005). Virus-like particle expression and assembly in plants: Hepatitis B and Norwalk viruses . Vaccine. 23. (15 SPEC. ISS.). p. 1851-1858.
Dougherty, LR, Durbin, CE, Hayden, EP, Klein, DN, Lahiri, DK, Maloney, B, Nurnberger, JI, Olino, TM(2005). Associations between a polymorphism in the serotonin transporter gene and multiple measures of child temperament. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 138B. (1). p. 113.
Ge, YW, Lahiri, DK, Maloney, B, Ge, YW, Lahiri, DK, Maloney, B(2005). Characterization of the APP proximal promoter and 5 '-untranslated regions: identification of cell-type specific domains and implications in APP gene expression and Alzheimer's disease . Faseb Journal. 19. (2). p. 653-+.
Ge, YW, Lahiri, D, Maloney, B, Ge, YW, Lahiri, D, Maloney, B(2005). Structural and functional characterization of the beta-secretase (BACE) gene promoter and its implication in Alzheimer's disease (AD). International Psychogeriatrics. 17. p. 293-294.
Ge, YW, Hardy, J, Lahiri, DK, Maloney, B, Wavrant-De Vrieze, F, Ge, YW, Hardy, J, Lahiri, DK, Maloney, B, Wavrant-De Vrieze, F(2005). Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease . Neurobiology of Aging. 26. (10). p. 1329-1341.
Bales, KR, Berg, DT, Chen, XM, Du, YS, Farlow, MR, Ge, YW, Lahiri, DK, Maloney, B, Paul, SM, Wei, X, et al.(2005). NF-kappa B mediates amyloid beta peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells . Molecular Brain Research. 136. (1-2). p. 177-188.
Lahiri, D.K., Ge, Y.-W., Maloney, B., Lahiri, D.K., Ge, Y.-W., Maloney, B.(2005). Characterization of the APP proximal promoter and 5′-untranslated regions: Identification or cell type-specific domains and implications in APP gene expression and Alzheimer's disease . FASEB Journal. 19. (6). p. 653-655.
Du, Y., Chen, X., Wei, X., Bales, K.R., Berg, D.T., Paul, S.M., Farlow, M.R., Maloney, B., Ge, Y.-W., Lahiri, D.K., et al.(2005). NF-κB mediates amyloid β peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells . Molecular Brain Research. 136. (1-2). p. 177-188.
Arntzen, CJ, Beuhner, N, Elkin, G, Huang, Z, Maloney, BJ, Mason, HS, Thanavala, Y, Arntzen, CJ, Beuhner, N, Elkin, G, et al.(2005). Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses . Vaccine. 23. (15). p. 1851-1858.
Bryan Maloney, Shayne A. Bellingham, Debomoy K. Lahiri, Sharon La Fontaine, Gerd Multhaup, James Camakaris(2004). Copper Depletion Down-regulates Expression of the Alzheimer's Disease Amyloid-β Precursor Protein Gene . J. Biol. Chem. 279. (19). p. 20378--20386. American Society for Biochemistry {\&} Molecular Biology ({ASBMB})
Sambamurti, K., Kinsey, R., Maloney, B., Ge, Y.-W., Lahiri, D.K., Sambamurti, K., Kinsey, R., Maloney, B., Ge, Y.-W., Lahiri, D.K.(2004). Gene structure and organization of the human β-secretase (BACE) promoter . FASEB Journal. 18. (9). p. 1034-1036.
Maloney, B., Ge, Y.-W., Greig, N., Lahiri, D.K., Maloney, B., Ge, Y.-W., Greig, N., Lahiri, D.K.(2004). Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: Implications in Alzheimer's disease . FASEB Journal. 18. (11). p. 1288-1290.
Ge, YW, Kinsey, R, Lahiri, DK, Maloney, B, Sambamurti, K, Ge, YW, Kinsey, R, Lahiri, DK, Maloney, B, Sambamurti, K(2004). Gene structure and organization of the human beta-secretase (BACE) promoter . Faseb Journal. 18. (6). p. 1034-+.
Ge, YW, Ghosh, C, Lahiri, DK, Maloney, B, Song, W, Ge, YW, Ghosh, C, Lahiri, DK, Maloney, B, Song, W(2004). Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region . Journal of Neurochemistry. 90. (6). p. 1432-1444.
Ge, YW, Lahiri, DK, Maloney, B, Sambamurti, K, Ge, YW, Lahiri, DK, Maloney, B, Sambamurti, K(2004). Functional characterization of the 5 ' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression . Faseb Journal. 18. (6). p. 1037-+.
Bellingham, SA, Camakaris, J, La Fontaine, S, Lahiri, DK, Maloney, B, Multhaup, G(2004). Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene . Journal of Biological Chemistry. 279. (19). p. 20378-20386.
Bellingham, S.A., Lahiri, D.K., Maloney, B., La Fontaine, S., Multhaup, G., Camakaris, J.(2004). Copper Depletion Down-regulates Expression of the Alzheimer's Disease Amyloid-β Precursor Protein Gene . Journal of Biological Chemistry. 279. (19). p. 20378-20386.
Ge, Y.-W., Maloney, B., Sambamurti, K., Lahiri, D.K.(2004). Functional characterization of the 5′ flanking region of the BACE gene: Identification of a 91 bp fragment involved in basal level of BACE promoter expression . FASEB Journal. 18. (9). p. 1037-1039.
Ge, Y.-W., Ghosh, C., Song, W., Maloney, B., Lahiri, D.K.(2004). Mechanism of promoter activity of the β-amyloid precursor protein gene in different cell lines: Identification of a specific 30 bp fragment in the proximal promoter region . Journal of Neurochemistry. 90. (6). p. 1432-1444.
Ge, YW, Greig, N, Lahiri, DK, Maloney, B(2004). Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease . Faseb Journal. 18. (9). p. 1288-+.
Ge, YW, Hardy, J, Lahiri, DK, Maloney, B, Vrize, FWD, Ge, YW, Hardy, J, Lahiri, DK, Maloney, B, Vrize, FWD(2003). Characterization of polymorphisms in the APP gene promoter involved in Alzheimer's disease. Journal of Neurochemistry. 85. p. 45.
Adams, H., Maloney, B. J., Mason, H. S., Simkova, T., Adams, H., Maloney, B. J., Mason, H. S., Simkova, T.(1997). Expression and subcellular targeting of a synthetic E-coli enterotoxin B subunit gene in potato. Plant Physiology. 114. p. 1582.
Guo, P., Scholz, E., Maloney, B., Welniak, E., Guo, P., Scholz, E., Maloney, B., Welniak, E.(1994). Construction of recombinant avian infectious laryngotracheitis virus expressing the β-galactosidase gene and DNA sequencing of the insertion region . Virology. 202. (2). p. 771-781.
Guo, P., Scholz, E., Turek, J., Nodgreen, R., Maloney, B., Guo, P., Scholz, E., Turek, J., Nodgreen, R., Maloney, B.(1993). Assembly pathway of avian infectious laryngotracheitis virus . American Journal of Veterinary Research. 54. (12). p. 2031-2039.
OTHER
BOOK
Lahiri, D.K., Maloney, B., Zawia, N.H.(2009). How biochemical pathways for disease may be triggered by early-life events . Current Hypotheses and Research Milestones in Alzheimer's Disease. p. 205-214.
Lahiri, D.K., Maloney, B.(2009). Genomics of Brain Aging: Apolipoprotein E . Encyclopedia of Neuroscience. p. 685-693.
Maloney, Bryan, Lahiri, Debomoy K., Maccioni, RB, Perry, G, Zawia, Nasser H.(2009). How Biochemical Pathways for Disease May be Triggered by Early-Life Events . Current Hypotheses and Research Milestones in Alzheimer's Disease. p. 205-214.
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