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Hire Alan C.

Spain

R&D Formulation Scientist and Project Manager

Profile Summary

Out of the box thinking PhD graduate with both academic and industrial experience. Innovative research and development background working in, leading, and managing internal and external projects in collaboration with Contract Research/Manufacturing Organisations, and academic partners to develop and upscale innovative products. Product driven scientist with extensive knowledge in the extraction, formulation, and characterisation of proteins and peptides, vitamins, polyphenols, antioxidants, and other active ingredients. Experienced in many formulation techniques including extrusion, tableting, granulation, powder catch technology and spray drying. Broad analytical background skilled in many characterisation techniques i.e., HPLC, DVS, XRD, DSC, NMR, and in vitro bioactivity assays. Strong publication background in peer reviewed academic journals as well as patent publications.

Subject Matter Expertise

• ☆ Materials Science & Engineering
• ☆ Separation & Purification
• ☆ Antioxidants
• ☆ Food Science
• ☆ Food Chemistry
• ☆ Protein/Enzyme Engineering
• ☆ Recipe Formulation
• ☆ Cooking
• ☆ Diabetes
• ☆ Cardiovascular Disease
• ☆ Technology Scouting
• ☆ Formulation

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Digital Strategy Consulting, Scientific and Technical Consulting, Regulatory Consulting

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Data Processing, Data Insights

Product Development Formulation, Stability/Shelf Life Testing, Product Evaluation, Material Sourcing, Manufacturing, Concept Development, Prototyping

Work Experience

Formulation Scientist and Project Manager

DSM Nutritional Products

January 2017 - June 2021

Postdoctroral Researcher

University of Limerick

September 2014 - December 2016

Postdoctroral Researcher

University of Limerick

November 2013 - March 2014

Chef De Partie

Early Career

June 2002 - November 2007

Education

Ph.D. in Food Biochemistry

University of Limerick

November 2009 - October 2013

BSc (Hons) Food Science and Health

University of Limerick

September 2005 - May 2009

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Miquel Martin, Matteo M. Pusceddu, Joan Teichenné, Teresa Negra, Alan Connolly, Xavier Escoté, Helena Torrell Galceran, Adrià Cereto Massagué, Iris Samarra Mestre, Antoni del Pino Rius, et al. (2023). Preventive Treatment with Astaxanthin Microencapsulated with Spirulina Powder, Administered in a Dose Range Equivalent to Human Consumption, Prevents LPS-Induced Cognitive Impairment in Rats . Nutrients.

Miquel Martin, Matteo M. Pusceddu, Joan Teichenné, Teresa Negra, Alan Connolly, Xavier Escoté, Helena Torrell Galceran, Adrià Cereto Massagué, Iris Samarra, Antoni del Pino Rius, et al. (2023). Preventive Treatment with Astaxanthin Microencapsulated with Spirulina Powder, Administered in a Dose Range Equivalent to Human Consumption, Prevents LPS-Induced Cognitive Impairment in Rats . Nutrients.

(2021). Generation of phenolic-rich extracts from brewers' spent grain and characterisation of their in vitro and in vivo activities. Innovative Food Science & Emerging Technologies.

Cermeño, M., Connolly, A., O'Keeffe, M.B., Flynn, C., Alashi, A.M., Aluko, R.E., FitzGerald, R.J.(2019). Identification of bioactive peptides from brewers’ spent grain and contribution of Leu/Ile to bioactive potency . Journal of Functional Foods. 60.

Connolly, A., Cermeño, M., Crowley, D., O'Callaghan, Y., O'Brien, N.M., FitzGerald, R.J.(2019). Characterisation of the in vitro bioactive properties of alkaline and enzyme extracted brewers' spent grain protein hydrolysates . Food Research International. 121. p. 524-532.

Cermeño, M., Felix, M., Connolly, A., Brennan, E., Coffey, B., Ryan, E., FitzGerald, R.J.(2019). Role of carbohydrate conjugation on the emulsification and antioxidant properties of intact and hydrolysed whey protein concentrate . Food Hydrocolloids. 88. p. 170-179.

Connolly, A., O'Keeffe, M.B., Nongonierma, A.B., Piggott, C.O., FitzGerald, R.J.(2017). Isolation of peptides from a novel brewers spent grain protein isolate with potential to modulate glycaemic response . International Journal of Food Science and Technology. 52. (1). p. 146-153.

Crowley, D., O'Callaghan, Y., McCarthy, A.L., Connolly, A., Fitzgerald, R.J., O'Brien, N.M.(2017). Aqueous and enzyme-extracted phenolic compounds from brewers' spent grain (BSG): Assessment of their antioxidant potential . Journal of Food Biochemistry. 41. (3).

(2016). Effect of enzyme-extracted brewers’ spent grain protein hydrolysates on inflammatory response in cells associated with atherosclerosis . Proceedings of the Nutrition Society.

Mccarthy, A.L., O'callaghan, Y.C., Connolly, A., Piggott, C.O., Fitzgerald, R.J., O'Brien, N.M.(2015). A study of the ability of bioactive extracts from brewers' spent grain to enhance the antioxidant and immunomodulatory potential of food formulations following in vitro digestion . International Journal of Food Sciences and Nutrition. 66. (2). p. 230-235.

(2015). Effect of Brewers' spent grain (BSG) phenolic extracts on cell viability and protective effect against oxidant-induced DNA single strand breaks in U937 cells . Proceedings of the Nutrition Society.

Connolly, A., O'Keeffe, M.B., Piggott, C.O., Nongonierma, A.B., Fitzgerald, R.J.(2015). Generation and identification of angiotensin converting enzyme (ACE) inhibitory peptides from a brewers' spent grain protein isolate . Food Chemistry. 176. p. 64-71.

Crowley, D., O'Callaghan, Y., McCarthy, A., Connolly, A., Piggott, C.O., FitzGerald, R.J., O'Brien, N.M.(2015). Immunomodulatory potential of a brewers' spent grain protein hydrolysate incorporated into low-fat milk following in vitro gastrointestinal digestion . International Journal of Food Sciences and Nutrition. 66. (6). p. 672-676.

Mccarthy, A.L., O'Callaghan, Y.C., Connolly, A., Piggott, C.O., Fitzgerald, R.J., O'Brien, N.M.(2014). Phenolic-enriched fractions from brewers' spent grain possess cellular antioxidant and immunomodulatory effects in cell culture model systems . Journal of the Science of Food and Agriculture. 94. (7). p. 1373-1379.

Piggott, C.O., Connolly, A., FitzGerald, R.J.(2014). Application of ultrafiltration in the study of phenolic isolates and melanoidins from pale and black brewers' spent grain . International Journal of Food Science and Technology. 49. (10). p. 2252-2259.

Connolly, A., Piggott, C.O., FitzGerald, R.J.(2014). Technofunctional properties of a brewers' spent grain protein-enriched isolate and its associated enzymatic hydrolysates . LWT - Food Science and Technology. 59. (2P1). p. 1061-1067.

Zhu, Y.-S., Connolly, A., Guyon, A., Fitzgerald, R.J.(2014). Solubilisation of calcium and magnesium from the marine red algae Lithothamnion calcareum . International Journal of Food Science and Technology. 49. (6). p. 1600-1606.

Connolly, A., Piggott, C.O., FitzGerald, R.J.(2014). In vitro α-glucosidase, angiotensin converting enzyme and dipeptidyl peptidase-IV inhibitory properties of brewers' spent grain protein hydrolysates . Food Research International. 56. p. 100-107.

McCarthy, A.L., O'Callaghan, Y.C., Neugart, S., Piggott, C.O., Connolly, A., Jansen, M.A.K., Krumbein, A., Schreiner, M., FitzGerald, R.J., O'Brien, N.M.(2013). The hydroxycinnamic acid content of barley and brewers' spent grain (BSG) and the potential to incorporate phenolic extracts of BSG as antioxidants into fruit beverages . Food Chemistry. 141. (3). p. 2567-2574.

(2013). Cellular in vitro bioactivity of protein hydrolysates from brewers' spent grain . Proceedings of the Nutrition Society.

Connolly, A., Piggott, C.O., Fitzgerald, R.J.(2013). Characterisation of protein-rich isolates and antioxidative phenolic extracts from pale and black brewers' spent grain . International Journal of Food Science and Technology. 48. (8). p. 1670-1681.

McCarthy, A.L., O'Callaghan, Y.C., Connolly, A., Piggott, C.O., FitzGerald, R.J., O'Brien, N.M.(2013). In vitro antioxidant and anti-inflammatory effects of brewers' spent grain protein rich isolate and its associated hydrolysates . Food Research International. 50. (1). p. 205-212.

McCarthy, A.L., O&#39;Callaghan, Y.C., Connolly, A., Piggott, C.O., Fitzgerald, R.J., O&#39;Brien, N.M.(2013). Brewers' spent grain (BSG) protein hydrolysates decrease hydrogen peroxide (H<inf>2</inf>O<inf>2</inf>)-induced oxidative stress and concanavalin-A (con-A) stimulated IFN-γ production in cell culture . Food and Function. 4. (11). p. 1709-1716.

McCarthy, A.L., O&#39;Callaghan, Y.C., Connolly, A., Piggott, C.O., Fitzgerald, R.J., O&#39;Brien, N.M.(2012). Phenolic extracts of brewers' spent grain (BSG) as functional ingredients - Assessment of their DNA protective effect against oxidant-induced DNA single strand breaks in U937 cells . Food Chemistry. 134. (2). p. 641-646.

BOOK CHAPTER

Alexandra Teleki and Christos Tsekou and Alan Connolly(2022). The Role of Bio‐based Excipients in the Formulation of Lipophilic Nutraceuticals . High‐Performance Materials from Bio‐based Feedstocks. p. 315--336. Wiley