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Kazakhstan

USD 52 /hr

Kazakhstan-based Pharmaceutical and Biotech Scientist

Profile Summary

Software and IT: Python (data curation, plotting, curve fitting, statistics, ML), non-NGC bioinformatics, reference managers, assorted equipment soft, project management software; Science and tech writing: manuscript writing, grant application and reporting, lab-scale process documentation and SOP writing Biotech: DNA/plasmid manipulation (PCR, simple cloning); bacterial cells transformation, selection, cultivation, harvest, and lysis; PAGE, ELISA, FPLC, TFF, and other wet lab methods Analytical: HPLC(MS), UV, fluorometry, TLC, AAS, titration, sample handling, extraction, derivatization, method development and validation Project management and leadership: decision making and planning, the ability to focus on MVP

Subject Matter Expertise

• ☆ Materials Science & Engineering
• ☆ Microencapsulation
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ PCR
• ☆ Plasmid DNA
• ☆ Data Analysis
• ☆ Data Management
• ☆ Data Manipulation
• ☆ Blotting
• ☆ Python
• ☆ Pharmacy
• ☆ Drug Development
• ☆ Oncology
• ☆ Project Management

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting

Research Technology Scouting, Fact Checking, Gap Analysis

Consulting Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

Product Development Formulation, Recipe Development, Deformulation, Product Evaluation, Product Validation, Quality Assurance & Control (QA/QC)

Work Experience

Junior Researcher

Research Center of Biotechnology RAS, Moscow

July 2015 - September 2022

Junior Researcher

Research Center of Molecular Diagnostics and Therapy LLC, Moscow

July 2014 - July 2015

Pharmaceutical QC specialist

Roszdravnadzor Moscow lab

February 2013 - July 2014

Education

PhD, Biochemistry

Research Center of Biotechnology RAS

September 2016 - Present

Master in Pharmacy

I.M. Sechenov Moscow Medical Academy - Russian Federation

September 2008 - July 2013

Certifications

• Yandex courses Machine Learning and Data Analysis specialization

  Stepik.com

  January 2020 - Present

Publications

JOURNAL ARTICLE

Vladimir Zenin, Maria Yurkova, Andrey Tsedilin, Alexey Fedorov(2022). Enfuvirtide biosynthesis in thermostable chaperone-based fusion . Biotechnology Reports. 35. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e00734. Elsevier {BV}

Sokol, M., Zenin, V., Yabbarov, N., Mollaev, M., Zabolotsky, A., Mollaeva, M., Fomicheva, M., Kuznetsov, S., Popenko, V., Seregina, I., et al.(2021). Validated HPLC method for paclitaxel determination in PLGA submicron particles conjugated with α-fetoprotein third domain: Sample preparation case study,Méthode HPLC validée pour la détermination du paclitaxel dans des submicroniques PLGA conjuguées au troisième domaine de l’α-foetoprotéine: étude de cas sur la préparation des échantillons . Annales Pharmaceutiques Francaises.

Yurkova, M.S., Zenin, V.A., Sadykhov, E.G., Fedorov, A.N.(2020). Dimerization of Antimicrobial Peptide Polyphemusin I into One Polypeptide Chain: Theoretical and Practical Consequences . Applied Biochemistry and Microbiology. 56. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 893-897.

Zenin, V.A., Novikova, L.A., Yurkova, M.S., Savvin, I.O., Kurov, K.A., Fedorov, A.N.(2019). Chemical Modification of Fusion Protein Based on the Thermus thermophilus GroEL Chaperon with AEBSF Protease Inhibitor . Applied Biochemistry and Microbiology. 55. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 649-653.

Yurkova, M.S., Savvin, O.I., Zenin, V.A., Fedorov, A.N.(2019). Design and Characterization of a Methionineless Variant of Thermostable Chaperon GroEL from Thermus thermophilus . Applied Biochemistry and Microbiology. 55. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 112-116.

Yurkova, M.S., Zenin, V.A., Sadykhov, E.G., Fedorov, A.N.(2019). Dimerization of the antimicrobial peptide polyphemusin I into one polypeptide chain: Theoretical and practical consequences . Biotekhnologiya. 35. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 36-41.

Yurkova, M.S., Zenin, V.A., Nagibina, G.S., Melnik, B.S., Fedorov, A.N.(2019). Physico-Chemical Characterization of Permutated Variants of Chaperone GroEL Apical Domain . Applied Biochemistry and Microbiology. 55. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 588-595.

Sokol, M.B., Nikolskaya, E.D., Yabbarov, N.G., Zenin, V.A., Faustova, M.R., Belov, A.V., Zhunina, O.A., Mollaev, M.D., Zabolotsky, A.I., Tereshchenko, O.G., et al.(2019). Development of novel PLGA nanoparticles with co-encapsulation of docetaxel and abiraterone acetate for a highly efficient delivery into tumor cells . Journal of Biomedical Materials Research - Part B Applied Biomaterials. 107. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1150-1158.

Yurkova, M.S., Sharapova, O.A., Zenin, V.A., Fedorov, A.N.(2019). Versatile format of minichaperone-based protein fusion system . Scientific Reports. 9. (1).

Kurov, K.A., Savvin, O.I., Yurkova, M.S., Zenin, V.A., Nagibina, G.S., Melnik, B.S., Fedorov, A.N.(2019). Physicochemical Characteristics of a Variant of Chaperon GroEL Apical Domain Designed to Enhance the Expression and Stability of Target Proteins . Applied Biochemistry and Microbiology. 55. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 765-770.

Kurov, K.A., Savvin, O.I., Yurkova, M.S., Zenin, V.A., Nagibina, G.S., Melnik, B.S., Fedorov, A.N.(2018). Physicochemical characteristics of modification of chaperon groel apical domain designed to enhance expression and stability of target proteins,Физико-химическая характеристика варианта апикального домена шаперона GroEL для повышения уровня биосинтеза и увеличения стабильности целевых белков . Biotekhnologiya. 34. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 43-50.

Nikitin, N.A., Zenin, V.A., Trifonova, E.A., Ryabchevskaya, E.M., Kondakova, O.A., Fedorov, A.N., Atabekov, J.G., Karpova, O.V.(2018). Assessment of structurally modified plant virus as a novel adjuvant in toxicity studies . Regulatory Toxicology and Pharmacology. 97. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 127-133.

Nikitin, N.A., Zenin, V.A., Trifonova, E.A., Ryabchevskaya, E.M., Yurkova, M.S., Kondakova, O.A., Fedorov, A.N., Atabekov, J.G., Karpova, O.V.(2018). Data in support of toxicity studies of structurally modified plant virus to safety assessment . Data in Brief. 21. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1504-1507.

Nikolskaya, E.D., Zhunina, O.A., Yabbarov, N.G., Zenin, V.A., Tereshchenko, O.G., Fomicheva, M.V., Sokol, M.B., Lobanov, A.V., Severin, E.S.(2017). Antitumor activity of carboplatin in the composition of a copolymer of lactic and glycolic acids . Russian Chemical Bulletin. 66. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1867-1872.

Nikolskaya, E.D., Zhunina, O.A., Yabbarov, N.G., Zenin, V.A., Tereshchenko, O.G., Fomicheva, M.V., Sokol, M.B., Lobanov, A.V., Severin, E.S.(2017). Erratum to: Antitumor activity of carboplatin in the composition of a copolymer of lactic and glycolic acids (Russian Chemical Bulletin, (2017), 66, 10, (1867-1872), 10.1007/s11172-017-1959-5) . Russian Chemical Bulletin. 66. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2348.

Trifonova, E.A., Zenin, V.A., Nikitin, N.A., Yurkova, M.S., Ryabchevskaya, E.M., Putlyaev, E.V., Donchenko, E.K., Kondakova, O.A., Fedorov, A.N., Atabekov, J.G., et al.(2017). Study of rubella candidate vaccine based on a structurally modified plant virus . Antiviral Research. 144. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 27-33.