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Profile Details
Create Project
USD 125 /hr
Hire Dr. Tyler G.
United States
USD 125 /hr

Delivering the Impossible, Chemist, Formulations, Non-Viral Vectors, Gene Therapy Scientist and Engineer

Profile Summary
Subject Matter Expertise
Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection
Product Development Formulation
Work Experience


Precision Biosciences

May 2017 - Present


University of North Carolina at Chapel Hill

- Present

PhD, Molecular Pharmaceutics and Engineering

University of North Carolina Chapel Hill

August 2013 - May 2017

  • Certification details not provided.
Das, M., Shen, L., Liu, Q., Goodwin, T.J., Huang, L.(2019). Nanoparticle Delivery of RIG-I Agonist Enables Effective and Safe Adjuvant Therapy in Pancreatic Cancer . Molecular Therapy. 27. (3). p. 507-517.
Shen, L., Li, J., Liu, Q., Song, W., Zhang, X., Tiruthani, K., Hu, H., Das, M., Goodwin, T.J., Liu, R., et al.(2018). Local Blockade of Interleukin 10 and C-X-C Motif Chemokine Ligand 12 with Nano-Delivery Promotes Antitumor Response in Murine Cancers . ACS Nano.
Zhou, J., Liu, M., Sun, H., Feng, Y., Xu, L., Chan, A.W.H., Tong, J.H., Wong, J., Chong, C.C.N., Lai, P.B.S., et al.(2018). Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy . Gut. 67. (5). p. 931-944.
Song, W., Shen, L., Wang, Y., Liu, Q., Goodwin, T.J., Li, J., Dorosheva, O., Liu, T., Liu, R., Huang, L.(2018). Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap . Nature Communications. 9. (1).
Buchanan, M.K., Needham, C.N., Neill, N.E., White, M.C., Kelly, C.B., Mastro-Kishton, K., Chauvigne-Hines, L.M., Goodwin, T.J., McIver, A.L., Bartolotti, L.J., et al.(2017). Glycoconjugated site-selective DNA-methylating agent targeting glucose transporters on glioma cells . Biochemistry. 56. (2). p. 421-440.
Goodwin, T.J., Shen, L., Hu, M., Li, J., Feng, R., Dorosheva, O., Liu, R., Huang, L.(2017). Liver specific gene immunotherapies resolve immune suppressive ectopic lymphoid structures of liver metastases and prolong survival . Biomaterials. 141. p. 260-271.
Hu, K., Miao, L., Goodwin, T.J., Li, J., Liu, Q., Huang, L.(2017). Quercetin Remodels the Tumor Microenvironment to Improve the Permeation, Retention, and Antitumor Effects of Nanoparticles . ACS Nano. 11. (5). p. 4916-4925.
Miao, L., Li, J., Liu, Q., Feng, R., Das, M., Lin, C.M., Goodwin, T.J., Dorosheva, O., Liu, R., Huang, L.(2017). Transient and Local Expression of Chemokine and Immune Checkpoint Traps to Treat Pancreatic Cancer . ACS Nano. 11. (9). p. 8690-8706.
Luo, C., Sun, J., Sun, B., Liu, D., Miao, L., Goodwin, T.J., Huang, L., He, Z.(2016). Facile Fabrication of Tumor Redox-Sensitive Nanoassemblies of Small-Molecule Oleate Prodrug as Potent Chemotherapeutic Nanomedicine . Small. 12. (46). p. 6353-6362.
Goodwin, T.J., Zhou, Y., Musetti, S.N., Liu, R., Huang, L.(2016). Local and transient gene expression primes the liver to resist cancer metastasis . Science Translational Medicine. 8. (364).
Goodwin, T., Huang, L.(2014). Nonviral vectors. we have come a long way . Advances in Genetics. 88. p. 1-12.