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United States
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Vaccine, Virology & Infectious Disease expert with biotech, academia and pharma experience
Profile Summary
Subject Matter Expertise
Services
Consulting
Scientific and Technical Consulting
Work Experience
AVP - Global Project Head
Sanofi
June 2023 - Present
Assistant Professor
Boston University Medical Campus
August 2017 - Present ![]()
Director, Viral Vaccines - Infectious Diseases
Moderna
May 2020 - June 2023
Assistant Professor
University of South Carolina School of Medicine
May 2015 - July 2017 ![]()
Assistant Professor
Tulane University School of Public Health
September 2013 - April 2015 ![]()
Postdoctoral Fellow
Yale University School of Medicine
November 2008 - August 2013 ![]()
Education
PhD (Microbiology & Immunology)
University of Texas Medical Branch at Galveston
June 2001 - November 2007 ![]()
Certifications
Publications
JOURNAL ARTICLE
Gloria I. Giraldo-Calderón, Arley Calle-Tobón, Paula Rozo-López, Tonya M. Colpitts, Yoonseong Park, Guillermo L. Rua-Uribe, Berlin Londono-Renteria(2020). Transcriptome of the Aedes aegypti Mosquito in Response to Human Complement Proteins . International Journal of Molecular Sciences. 21. (18). p. 6584. {MDPI} {AG}
Gloria I. Giraldo-Calderón, Arley Calle-Tobón, Paula Rozo-López, Tonya M. Colpitts, Yoonseong Park, Guillermo L. Rua-Uribe, Berlin Londono-Renteria (2020). Transcriptome of the <i>Aedes aegypti</i> Mosquito in Response to Human Complement Proteins . International Journal of Molecular Sciences.
Alexander S. Gold, Fabiana Feitosa-Suntheimer, Sultan Asad, Bukola Adeoye, John H. Connor, Tonya M. Colpitts(2020). Examining the Role of Niemann–Pick C1 Protein in the Permissiveness of Aedes Mosquitoes to Filoviruses . ACS Infectious Diseases. 6. (8). p. 2023--2028. American Chemical Society ({ACS})
Asad S, Feitosa-Suntheimer F, Gold A, Londono-Renteria B, Colpitts TM. Quantification of Antibody-dependent Enhancement of the Zika Virus in Primary Human Cells. J Vis Exp. 2019 Jan 18; (143).
Berlin L. Londono-Renteria, Heman Shakeri, Paula Rozo-Lopez, Michael J. Conway, Natasha Duggan, Majid Jaberi-Douraki, Tonya M. Colpitts(2018). Serosurvey of Human Antibodies Recognizing Aedes aegypti D7 Salivary Proteins in Colombia . Frontiers in Public Health. 6. Frontiers Media {SA}
Berlin Londono-Renteria, Andrea Troupin, Jenny C. Cardenas, Alex Hall, Omar G. Perez, Lucio Cardenas, Adam Hartstone-Rose, Scott B. Halstead, Tonya M. Colpitts(2017). A relevant in vitro human model for the study of Zika virus antibody-dependent enhancement . Journal of General Virology. 98. (7). p. 1702--1712. Microbiology Society
Andrea Troupin, Crystal Grippin, Tonya M. Colpitts(2017). Flavivirus Pathogenesis in the Mosquito Transmission Vector . Current Clinical Microbiology Reports. 4. (3). p. 115--123. Springer Nature
Hall A, Troupin A, Londono-Renteria B, Colpitts TM. Garlic Organosulfur Compounds Reduce Inflammation and Oxidative Stress during Dengue Virus Infection. Viruses. 2017 Jun 22; 9(6).
Tonya Colpitts, Alex Hall, Andrea Troupin, Berlin Londono-Renteria(2017). Garlic Organosulfur Compounds Reduce Inflammation and Oxidative Stress during Dengue Virus Infection . Viruses. 9. (7). p. 159. {MDPI} {AG}
Berlin Londono-Renteria, Julio C. Marinez-Angarita, Andrea Troupin, Tonya M. Colpitts(2017). Role of Mast Cells in Dengue Virus Pathogenesis . DNA and Cell Biology. 36. (6). p. 423--427. Mary Ann Liebert Inc
Troupin A, Shirley D, Londono-Renteria B, Watson AM, McHale C, Hall A, Hartstone-Rose A, Klimstra WB, Gomez G, Colpitts TM. A Role for Human Skin Mast Cells in Dengue Virus Infection and Systemic Spread. J Immunol. 2016 Dec 01; 197(11):4382-4391.
Andrea Troupin, Devon Shirley, Berlin Londono-Renteria, Alan M. Watson, Cody McHale, Alex Hall, Adam Hartstone-Rose, William B. Klimstra, Gregorio Gomez, Tonya M. Colpitts(2016). A Role for Human Skin Mast Cells in Dengue Virus Infection and Systemic Spread . The Journal of Immunology. 197. (11). p. 4382--4391. The American Association of Immunologists
Andrea Troupin, Berlin Londono-Renteria, Michael J. Conway, Erin Cloherty, Samuel Jameson, Stephen Higgs, Dana L. Vanlandingham, Erol Fikrig, Tonya M. Colpitts(2016). A novel mosquito ubiquitin targets viral envelope protein for degradation and reduces virion production during dengue virus infection . Biochimica et Biophysica Acta (BBA) - General Subjects. 1860. (9). p. 1898--1909. Elsevier {BV}
Berlin Londono-Renteria, Jenny C. Cardenas, Andrea Troupin, Tonya M. Colpitts(2016). Natural Mosquito-Pathogen Hybrid IgG4 Antibodies in Vector-Borne Diseases: A Hypothesis . Frontiers in Immunology. 7. Frontiers Media {SA}
Berlin Londono-Renteria, Andrea Troupin, Tonya M. Colpitts(2016). Arbovirosis and potential transmission blocking vaccines . Parasites & Vectors. 9. (1). Springer Nature
Berlin Londono-Renteria, Crystal Grippin, Jenny C. Cardenas, Andrea Troupin, Tonya M. Colpitts(2016). Human C5a Protein Participates in the Mosquito Immune Response Against Dengue Virus . J Med Entomol. 53. (3). p. 505--512. Oxford University Press ({OUP})
Londono-Renteria B, Colpitts TM. A Brief Review of West Nile Virus Biology. Methods Mol Biol. 2016; 1435:1-13.
Troupin A, Colpitts TM. Overview of West Nile Virus Transmission and Epidemiology. Methods Mol Biol. 2016; 1435:15-8.
Berlin Londono-Renteria, Andrea Troupin, Michael J Conway, Diana Vesely, Michael Ledizet, Christopher M. Roundy, Erin Cloherty, Samuel Jameson, Dana Vanlandingham, Stephen Higgs, et al.(2015). Dengue Virus Infection of Aedes aegypti Requires a Putative Cysteine Rich Venom Protein . PLoS Pathog. 11. (10). p. e1005202. Public Library of Science ({PLoS})
Berlin Londono-Renteria, Papa M. Drame, Thomas Weitzel, Reinaldo Rosas, Crystal Gripping, Jenny C. Cardenas, Marcela Alvares, Dawn M Wesson, Anne Poinsignon, Franck Remoue, et al.(2015). An. gambiae gSG6-P1 evaluation as a proxy for human-vector contact in the Americas: a pilot study . Parasites Vectors. 8. (1). Springer Science $\mathplus$ Business Media
Michael J. Conway, Tonya M. Colpitts, Erol Fikrig(2014). Role of the Vector in Arbovirus Transmission . Annual Review of Virology. 1. (1). p. 71--88. Annual Reviews
Conway MJ, Colpitts TM, Fikrig E. Role of the Vector in Arbovirus Transmission. Annu Rev Virol. 2014 Nov; 1(1):71-88.
Júlia M. da Silva Voorham, Izabela A. Rodenhuis-Zybert, Nilda Vanesa Ayala Nuñez, Tonya M. Colpitts, Heidi van der Ende-Metselaar, Erol Fikrig, Michael S. Diamond, Jan Wilschut, Jolanda M. Smit, Xia Jin(2012). Antibodies against the Envelope Glycoprotein Promote Infectivity of Immature Dengue Virus Serotype 2 . PLoS ONE. 7. (3). p. e29957. Public Library of Science ({PLoS})
Tonya M. Colpitts, Jonathan Cox, Dana L. Vanlandingham, Fabiana M. Feitosa, Gong Cheng, Sebastian Kurscheid, Penghua Wang, Manoj N. Krishnan, Stephen Higgs, Erol Fikrig, et al.(2011). Alterations in the Aedes aegypti Transcriptome during Infection with West Nile, Dengue and Yellow Fever Viruses . PLoS Pathog. 7. (9). p. e1002189. Public Library of Science ({PLoS})
Tonya M. Colpitts, Sebastian Barthel, Penghua Wang, Erol Fikrig, Eng Eong Ooi(2011). Dengue Virus Capsid Protein Binds Core Histones and Inhibits Nucleosome Formation in Human Liver Cells . PLoS ONE. 6. (9). p. e24365. Public Library of Science ({PLoS})
Tonya M. Colpitts, Jonathan Cox, Annie Nguyen, Fabiana Feitosa, Manoj N. Krishnan, Erol Fikrig(2011). Use of a tandem affinity purification assay to detect interactions between West Nile and dengue viral proteins and proteins of the mosquito vector . Virology. 417. (1). p. 179--187. Elsevier {BV}
Gong Cheng, Lei Liu, Penghua Wang, Yue Zhang, Yang O. Zhao, Tonya M. Colpitts, Fabiana Feitosa, John F. Anderson, Erol Fikrig, Ali Amara(2011). An In Vivo Transfection Approach Elucidates a Role for Aedes aegypti Thioester-Containing Proteins in Flaviviral Infection . PLoS ONE. 6. (7). p. e22786. Public Library of Science ({PLoS})
Bindu Sukumaran, Juliana E. Mastronunzio, Sukanya Narasimhan, Sarah Fankhauser, Pradeep D. Uchil, Roie Levy, Morven Graham, Tonya Michelle Colpitts, Cammie F. Lesser, Erol Fikrig(2010). Anaplasma phagocytophilum AptA modulates Erk1/2 signalling . Cellular Microbiology. 13. (1). p. 47--61. Wiley-Blackwell
Eric M. Vela, Tonya M. Colpitts, Lihong Zhang, Robert A. Davey, Judith F. Aronson(2008). Pichindé virus is trafficked through a dynamin 2 endocytic pathway that is dependent on cellular Rab5- and Rab7-mediated endosomes . Arch Virol. 153. (7). p. 1391--1396. Springer Science $\mathplus$ Business Media
Vela EM, Colpitts TM, Zhang L, Davey RA, Aronson JF. Pichindé virus is trafficked through a dynamin 2 endocytic pathway that is dependent on cellular Rab5- and Rab7-mediated endosomes. Arch Virol. 2008; 153(7):1391-6.<a data-target="#related_profiles_18543061" data-toggle="collapse">View Related Profiles</a>.<div class="collapse" id="related_profiles_18543061"><a href="http://profiles.bu.edu/Robert.Davey" target="_blank">Davey, Robert</a><br /><a href="http://profiles.bu.edu/Tonya.Colpitts" target="_blank">Colpitts, Tonya</a><br /></div>.
Tonya M. Colpitts, Andrew C. Moore, Andrey A. Kolokoltsov, Robert A. Davey(2007). Venezuelan equine encephalitis virus infection of mosquito cells requires acidification as well as mosquito homologs of the endocytic proteins Rab5 and Rab7 . Virology. 369. (1). p. 78--91. Elsevier {BV}
Eric M. Vela, Lihong Zhang, Tonya M. Colpitts, Robert A. Davey, Judith F. Aronson(2007). Arenavirus entry occurs through a cholesterol-dependent, non-caveolar, clathrin-mediated endocytic mechanism . Virology. 369. (1). p. 1--11. Elsevier {BV}
Kolokoltsov AA, Wang E, Colpitts TM, Weaver SC, Davey RA. Pseudotyped viruses permit rapid detection of neutralizing antibodies in human and equine serum against Venezuelan equine encephalitis virus. Am J Trop Med Hyg. 2006 Oct; 75(4):702-9.<a data-target="#related_profiles_17038698" data-toggle="collapse">View Related Profiles</a>.<div class="collapse" id="related_profiles_17038698"><a href="http://profiles.bu.edu/Robert.Davey" target="_blank">Davey, Robert</a><br /><a href="http://profiles.bu.edu/Tonya.Colpitts" target="_blank">Colpitts, Tonya</a><br /></div>.
Weiner DM, Goodman MW, Colpitts TM, Feddock MA, Duggento KL, Nash NR, Levey AI, Brann MR. Functional screening of drug target genes: m1 muscarinic acetylcholine receptor phenotypes in degenerative dementias. Am J Pharmacogenomics. 2004; 4(2):119-28.
David M Weiner, Matilda W Goodman, Tonya M Colpitts, Michelle A Feddock, Kate L Duggento, Norman R Nash, Allan I Levey, Mark R Brann(2004). Functional Screening of Drug Target Genes . American Journal of PharmacoGenomics. 4. (2). p. 119--128. Springer Science $\mathplus$ Business Media
OTHER
Berlin Londono-Renteria, Tonya M. Colpitts(2016). A Brief Review of West Nile Virus Biology . West Nile Virus. p. 1--13. Springer Nature
Andrea Troupin, Tonya M. Colpitts(2016). Overview of West Nile Virus Transmission and Epidemiology . West Nile Virus. p. 15--18. Springer Nature