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USD 300 /hr

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☆☆☆☆☆

Hire Dr. Tal K.

United States

USD 300 /hr

Biotech & Gene Therapy Expert | AAV & Non-Viral Delivery | CRISPR | R&D Strategy | External Innovation & Partnerships

Profile Summary

I am a scientific leader with a Ph.D. in Molecular Biology & Neuroscience from Princeton and extensive experience in gene therapy, gene editing, and drug development. My expertise spans AAV and non-viral delivery platforms for CNS, muscle, liver, and ocular diseases, as well as R&D strategy, external innovation, and strategic partnerships. Expertise & Skills: ✔ Gene Therapy & Gene Editing – AAV, CRISPR/Cas9, RNA therapeutics, viral & non-viral vectors ✔ Delivery Platforms – AAV vector engineering, LNP, genome engineering for precision medicine ✔ R&D Strategy & Portfolio Management – Translating discovery-stage research into therapeutic programs ✔ External Innovation & Business Development – Landscape analysis, due diligence, technology scouting ✔ Cross-Functional Leadership – Managing multi-disciplinary teams, partnerships, and collaborations Professional Experience & Research: • Led the development of an all-in-one AAV platform for CRISPR/Cas9 delivery to CNS & muscle, securing and executing a strategic partnership with Regeneron. • Managed multiple gene therapy pipeline programs in neurological, neuromuscular, liver, and rare diseases, driving preclinical proof-of-concept studies. • Evaluated emerging delivery technologies and identified key external partnerships to expand gene therapy capabilities. • Led cross-functional teams in early-stage R&D, technology evaluation, and platform innovation to advance gene editing approaches. Educational Background: 🎓 Ph.D. in Molecular Biology & Neuroscience – Princeton University I am passionate about leveraging cutting-edge genetic medicine and delivery technologies to develop transformative therapies. Open to consulting, collaborations, and strategic advisory roles in biotech and life sciences.

Subject Matter Expertise

• ★ Gene Editing/CRISPR
• ★ Drug Discovery
• ★ Gene Therapy
• ☆ Developmental Biology
• ☆ Microbiology
• ☆ Mammalian Biology
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Omics
• ☆ Proteomics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ DNA/Gene Synthesis
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ Molecular Ecology
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Neuroscience
• ☆ Neurochemistry
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Line Engineering
• ☆ Industrial Biotechnology
• ☆ Biomolecular Engineering
• ☆ English Language
• ☆ Drug Development
• ☆ Neurology
• ☆ Rare Diseases
• ☆ Drug Delivery Technologies
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Technology Scouting
• ☆ Literature Search
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Spec Sheets
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Language Translation
• ☆ Grant Writing
• ☆ Business Intelligence
• ☆ Risk Management
• ☆ Management Consulting

Services

• Writing
• Research
• Consulting

Writing Technical Writing, General Proofreading & Editing

Research Technology Scouting, Scientific and Technical Research, Systematic Literature Review

Consulting Business Strategy Consulting, Scientific and Technical Consulting

Work Experience

Director, Gene Editing

Intellia Therapeutics (United States)

April 2021 - January 2025

Associate Director, Gene Therapy

UCB Biosciences

October 2019 - March 2021

Senior Scientist, Vector Engineering

Ultragenyx Gene Therapy

September 2018 - October 2019

Research Scientist II, Discovery Biology

Vertex Pharmaceuticals (United States)

April 2015 - September 2018

Postdoctoral Fellow, Neurobiology

Harvard Medical School and Boston Children's Hospital

November 2012 - March 2015

Education

PHD Molecular Biology and Neuroscience (Molecular Biology)

Princeton University

September 2007 - November 2012

BS Biology

Emory University

August 2003 - May 2007

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Shlevkov E, Kramer T, Schapansky J, Matthew LaVoie, Schwarz TL (2016). Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility . Proceedings of the National Academy of Sciences of the United States of America.

Radomir Kratchmarov, Kramer T, Todd Greco, Taylor MP, Toh Hean Ch'ng, Cristea IM, Enquist LW (2013). Glycoproteins gE and gI are required for efficient KIF1A-dependent anterograde axonal transport of alphaherpesvirus particles in neurons . Journal of virology.

Tal Kramer, Enquist LW (2013). Directional spread of alphaherpesviruses in the nervous system . Viruses.

Tal Kramer, Todd Greco, Taylor MP, Ambrosini AE, Cristea IM, Enquist LW (2012). Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons . Cell host & microbe.

Taylor MP, Kramer T, Lyman MG, Radomir Kratchmarov, Enquist LW (2012). Visualization of an alphaherpesvirus membrane protein that is essential for anterograde axonal spread of infection in neurons . mBio.

Tal Kramer, Enquist LW (2012). Alphaherpesvirus infection disrupts mitochondrial transport in neurons . Cell host & microbe.

Kramer T, Todd Greco, Enquist LW, Cristea IM (2011). Proteomic characterization of pseudorabies virus extracellular virions . Journal of virology.

Tal Kramer, Luo Y, Li T, Yu F, Cristea IM (2009). Resolving the composition of protein complexes using a MALDI LTQ Orbitrap . Journal of the American Society for Mass Spectrometry.

Tal Kramer, Erin E. Dymek, Daniel Goduti, Elizabeth F. Smith (2006). A kinesin-like calmodulin-binding protein in<i>Chlamydomonas</i>: evidence for a role in cell division and flagellar functions . Journal of Cell Science.