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Hire Dr. Srividya V.

United States

Biomedical Scientist | Cancer Research | Molecular biology, Microbiology, MultiOmics, Pre-clinical assays | Science communication

Profile Summary

I am an enthusiastic and dedicated biomedical scientist experienced in project strategy/ management, scientific communication and preclinical assay development. I enjoy solving problems, am excited by the potential of cutting-edge technologies to redefine possibilities and passionate about advancing scientific discoveries to constructively impact human health. ✦ Multidisciplinary expert in Molecular biology, Microbiology, MultiOmics and Pre-clinical assays as demonstrated by 9 peer-reviewed publications across 3 cancer types including high impact journals like Gastroenterology. ✦ Outcome-driven innovator, identified a diagnostic biomarker (included in NCCN guidelines for colorectal cancer screening) and therapeutic intervention (investigator-initiated clinical trial with a pharmaceutical sponsor underway) for GI cancers. ✦ Skilled in delivering multiple initiatives and time critical projects; managed 15 research projects and contributed to securing $18M in federal and private research funding. ✦ Strong written and verbal communication skills with regulatory acumen led to mentorship of 23 junior colleagues, 21 conference presentations, successful completion of 3 collaborative projects and 1 patent filing. ✦ I love listening to different perspectives, am committed to building positive relationships and truly believe that we can find solutions to complex problems by working together. My hospital/metro park-based volunteer activities have led to engaging interactions with 150+ patients/ 500+ public citizens. Technical skills: ✦ Genetics / Molecular Biology: PCR, Mutagenesis, Cloning, Nucleic acid analysis, qPCR analysis, Fluorescence microscopy, in situ hybridization, Chromatin immunoprecipitation (ChIP), Chromatin immunoprecipitation by RNA purification (ChIRP), CRISPR-Cas9, Flow cytometry, High throughput sequencing, Copy number assays ✦ Protein biology: Recombinant protein expression, Subcellular fractionation, Protein-protein interaction assays, Western blotting, ELISA, Phospho-proteomics, Kinase and Glycotransferase enzyme assays ✦ In vitro / in vivo functional studies: Cell culture, Transient transfection, Lentiviral-based generation of stable lines, Cell-based phenotype assays, working knowledge of genetically engineered and tumor xenograft mouse models for interrogating function of genes and anti-cancer agents ✦ Informatics / Others: Mutation Surveyor, GraphPad Prism, Celleste, EndNote, GLP/GCP compliance, SOP development, Regulatory acumen

Subject Matter Expertise

• ★ Technical & Scientific Writing
• ☆ Microbiology
• ☆ Biochemical Assays
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Proteomics
• ☆ Cell Signaling Pathways
• ☆ Data Analysis
• ☆ Cancer Research
• ☆ Science Communication
• ☆ Project Management

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Feasibility Study, Fact Checking, Gap Analysis, Systematic Literature Review

Consulting Digital Strategy Consulting, Scientific and Technical Consulting, Regulatory Consulting

Data & AI Statistical Analysis, Data Insights

Product Development Product Evaluation, Product Validation

Work Experience

Case Comprehensive Cancer Center, Case Western Reserve University

- Present

Research Associate & Postdoctoral fellow

Case Western Reserve University

July 2012 - Present

Education

PhD Microbiology and Immunology

Rosalind Franklin University of Medicine and Science

October 2006 - June 2012

Certifications

• FDA Regulation in Entrepreneurship and Clinical Research Management

  Case western Reserve University

  November 2021 - Present

• GCP for Clinical Investigations of Drugs and Devices (FDA)

  CITI Program

  November 2021 - November 2021

Publications

JOURNAL ARTICLE

Andrew Blum, Vinay Varadan, Srividya Venkitachalam, Yan Guo, Ann Marie Kieber-Emmons, Lakshmeswari Ravi, Apoorva K. Chandar, Prasad Iyer, Marcia I. Canto, Jean Wang, et al.(2016). 758 Transcriptome Sequencing Identifies Potentially Functional Gene Fusions in Esophageal Adenocarcinomas . Gastroenterology. 150. (4). p. S153--S154. Elsevier {BV}

Srividya Venkitachalam, Leslie Revoredo, Vinay Varadan, Ryan E. Fecteau, Lakshmeswari Ravi, James Lutterbaugh, Sanford D. Markowitz, Joseph E. Willis, Thomas A. Gerken, Kishore Guda(2016). Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer . Sci. Rep. 6. p. 23642. Nature Publishing Group

Srividya Venkitachalam, Fu-Yu Chueh, Chao-Lan Yu(2012). Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene . Biochemical and Biophysical Research Communications. 417. (3). p. 1058--1062. Elsevier {BV}

Fu-Yu Chueh, King-Fu Leong, Robert J. Cronk, Srividya Venkitachalam, Samantha Pabich, Chao-Lan Yu(2011). Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription . Cellular Signalling. 23. (7). p. 1170--1178. Elsevier {BV}

Venkitachalam S, Chueh FY, Leong KF, Pabich S, Yu CL, Oncology reports, 2011, vol. 25, no. 3, pp. 677-683, 2011 .

Cooper JC, Shi M, Chueh FY, Venkitachalam S, Yu CL, International journal of oncology, 2010, vol. 36, no. 5, pp. 1201-1208, 2010 .