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USD 55 /hr
Hire Dr. Sneha K.
Australia
USD 55 /hr
Freelance Bioinformatician, Data analyst and academic editor | PhD in Immunology with experience in cancer research
Profile Summary
Subject Matter Expertise
Services
Writing
Technical Writing,
General Proofreading & Editing
Research
Fact Checking,
Scientific and Technical Research,
Secondary Data Collection
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis,
Data Visualization,
Big Data Analytics,
Data Cleaning,
Data Insights
Work Experience
Freelancing
Freelancing
January 2021 - Present
Education
PhD - Immunology
University of Melbourne
February 2014 - June 2018
Master of Science (Biotechnology)
University of Pune
July 2006 - June 2008
Bachelor of Science Honours (Biotechnology)
University of Pune
July 2003 - June 2006
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Teo, Z.L., O’Connor, M.J., Versaci, S., Clarke, K.A., Brown, E.R., Percy, L.W., Kuykhoven, K., Mintoff, C.P., Savas, P., Virassamy, B., et al.(2023). Combined PARP and WEE1 inhibition triggers anti-tumor immune response in BRCA1/2 wildtype triple-negative breast cancer . npj Breast Cancer. 9. (1).
Virassamy, B., Caramia, F., Savas, P., Sant, S., Wang, J., Christo, S.N., Byrne, A., Clarke, K., Brown, E., Teo, Z.L., et al.(2023). Intratumoral CD8<sup>+</sup> T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer . Cancer Cell. 41. (3). p. 585-601.e8.
van de Sandt, C.E., Nguyen, T.H.O., Gherardin, N.A., Crawford, J.C., Samir, J., Minervina, A.A., Pogorelyy, M.V., Rizzetto, S., Szeto, C., Kaur, J., et al.(2023). Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan . Nature Immunology. 24. (11). p. 1890-1907.
Li, R., Sant, S., Brown, E., Caramia, F., Nikolic, B., Clarke, K., Byrne, A., Lara Gonzalez, L.E., Savas, P., Luen, S.J., et al.(2023). Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer . Journal of the National Cancer Institute. 115. (7). p. 805-814.
Winship, A.L., Alesi, L.R., Sant, S., Stringer, J.M., Cantavenera, A., Hegarty, T., Requesens, C.L., Liew, S.H., Sarma, U., Griffiths, M.J., et al.(2022). Checkpoint inhibitor immunotherapy diminishes oocyte number and quality in mice . Nature Cancer. 3. (8). p. 1-13.
Winship, A.L., Alesi, L.R., Sant, S., Stringer, J.M., Cantavenera, A., Hegarty, T.(2022). IMMUNE CHECKPOINT INHIBITORS INDUCE APOPTOSIS IN OVARIAN FOLLICLES . Cancer Discovery. 12. (11). p. 2493.
Nguyen, T.H.O., Koutsakos, M., van de Sandt, C.E., Crawford, J.C., Loh, L., Sant, S., Grzelak, L., Allen, E.K., Brahm, T., Clemens, E.B., et al.(2021). Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients . Nature Communications. 12. (1).
El Bairi, K., Haynes, H.R., Blackley, E., Fineberg, S., Shear, J., Turner, S., de Freitas, J.R., Sur, D., Amendola, L.C., Gharib, M., et al.(2021). The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group . npj Breast Cancer. 7. (1).
Sant, S., Quiñones-Parra, S.M., Koutsakos, M., Grant, E.J., Loudovaris, T., Mannering, S.I., Crowe, J., van de Sandt, C.E., Rimmelzwaan, G.F., Rossjohn, J., et al.(2020). HLA-B<sub>*</sub>27:05 alters immunodominance hierarchy of universal influenza-specific CD8<sup>+</sup> T cells . PLoS Pathogens. 16. (8).
Byrne, A., Savas, P., Sant, S., Li, R., Virassamy, B., Luen, S.J., Beavis, P.A., Mackay, L.K., Neeson, P.J., Loi, S.(2020). Tissue-resident memory T cells in breast cancer control and immunotherapy responses . Nature Reviews Clinical Oncology. 17. (6). p. 341-348.
Loh, L., Gherardin, N.A., Sant, S., Grzelak, L., Crawford, J.C., Bird, N.L., Koay, H.-F., Van De Sandt, C.E., Moreira, M.L., Lappas, M., et al.(2020). Human mucosal-associated invariant t cells in older individuals display expanded tcrαβ clonotypes with potent antimicrobial responses . Journal of Immunology. 204. (5). p. 1119-1133.
Nüssing, S., Koay, H.-F., Sant, S., Loudovaris, T., Mannering, S.I., Lappas, M., d′Udekem, Y., Konstantinov, I.E., Berzins, S.P., Rimmelzwaan, G.F., et al.(2019). Divergent SATB1 expression across human life span and tissue compartments . Immunology and Cell Biology. 97. (5). p. 498-511.
van de Sandt, C.E., Clemens, E.B., Grant, E.J., Rowntree, L.C., Sant, S., Halim, H., Crowe, J., Cheng, A.C., Kotsimbos, T.C., Richards, M., et al.(2019). Challenging immunodominance of influenza-specific CD8<sup>+</sup> T cell responses restricted by the risk-associated HLA-A*68:01 allomorph . Nature Communications. 10. (1).
Sant, S., Jenkins, M.R., Dash, P., Watson, K.A., Wang, Z., Pizzolla, A., Koutsakos, M., Nguyen, T.H.O., Lappas, M., Crowe, J., et al.(2019). Human γδ T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation . Clinical and Translational Immunology. 8. (9).
Koutsakos, M., Illing, P.T., Nguyen, T.H.O., Mifsud, N.A., Crawford, J.C., Rizzetto, S., Eltahla, A.A., Clemens, E.B., Sant, S., Chua, B.Y., et al.(2019). Human CD8 <sup>+</sup> T cell cross-reactivity across influenza A, B and C viruses . Nature Immunology. 20. (5). p. 613-625.
Grant, E.J., Josephs, T.M., Loh, L., Clemens, E.B., Sant, S., Bharadwaj, M., Chen, W., Rossjohn, J., Gras, S., Kedzierska, K.(2018). Broad CD8 <sup>+</sup> T cell cross-recognition of distinct influenza A strains in humans . Nature Communications. 9. (1).
Nüssing, S., Sant, S., Koutsakos, M., Subbarao, K., Nguyen, T.H.O., Kedzierska, K.(2018). Innate and adaptive T cells in influenza disease . Frontiers of Medicine. 12. (1). p. 34-47.
Koutsakos, M., Wheatley, A.K., Loh, L., Clemens, E.B., Sant, S., Nüssing, S., Fox, A., Chung, A.W., Laurie, K.L., Hurt, A.C., et al.(2018). Circulating T<sub>FH</sub> cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity . Science Translational Medicine. 10. (428).
Wilgenburg, B., Loh, L., Chen, Z., Pediongco, T.J., Wang, H., Shi, M., Zhao, Z., Koutsakos, M., Nüssing, S., Sant, S., et al.(2018). MAIT cells contribute to protection against lethal influenza infection in vivo . Nature Communications. 9. (1).
Wang, Z., Zhu, L., Nguyen, T.H.O., Wan, Y., Sant, S., Quiñones-Parra, S.M., Crawford, J.C., Eltahla, A.A., Rizzetto, S., Bull, R.A., et al.(2018). Clonally diverse CD38<sup>+</sup>HLA-DR<sup>+</sup>CD8<sup>+</sup> T cells persist during fatal H7N9 disease . Nature Communications. 9. (1).
Nguyen, T.H.O., Sant, S., Bird, N.L., Grant, E.J., Clemens, E.B., Koutsakos, M., Valkenburg, S.A., Gras, S., Lappas, M., Jaworowski, A., et al.(2018). Perturbed CD8<sup>+</sup> T cell immunity across universal influenza epitopes in the elderly . Journal of Leukocyte Biology. 103. (2). p. 321-339.
Pizzolla, A., Nguyen, T.H.O., Sant, S., Jaffar, J., Loudovaris, T., Mannering, S.I., Thomas, P.G., Westall, G.P., Kedzierska, K., Wakim, L.M.(2018). Influenza-specific lung-resident memory t cells are proliferative and polyfunctional and maintain diverse TCR profiles . Journal of Clinical Investigation. 128. (2). p. 721-733.
Sant, S., Grzelak, L., Wang, Z., Pizzolla, A., Koutsakos, M., Crowe, J., Loudovaris, T., Mannering, S.I., Westall, G.P., Wakim, L.M., et al.(2018). Single-cell approach to influenza-specific CD8<sup>+</sup> T cell receptor repertoires across different age groups, tissues, and following influenza virus infection . Frontiers in Immunology. 9. (JUN).
Grant, E.J., Nüssing, S., Sant, S., Clemens, E.B., Kedzierska, K.(2017). The role of CD27 in anti-viral T-cell immunity . Current Opinion in Virology. 22. p. 77-88.
Loh, L., Wang, Z., Sant, S., Koutsakos, M., Jegaskanda, S., Corbett, A.J., Liu, L., Fairlie, D.P., Crowe, J., Rossjohn, J., et al.(2016). Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation . Proceedings of the National Academy of Sciences of the United States of America. 113. (36). p. 10133-10138.
OTHER
Nguyen, T.H.O., Koutsakos, M., van de Sandt, C.E., Crawford, J.C., Loh, L., Sant, S., Grzelak, L., Allen, E.K., Brahm, T., Clemens, E.B., et al.(2020). In-concert immune dynamics during natural influenza virus infection and recovery in acute hospitalized patients . medRxiv.
van Wilgenburg, B., Loh, L., Chen, Z., Pediongco, T.J., Wang, H., Shi, M., Zhao, Z., Koutsakos, M., Nüssing, S., Sant, S., et al.(2018). MAIT cells contribute to protection against lethal influenza infection in vivo . bioRxiv.