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United States
USD 150 /hr

MD/PhD • Neuroscience • Scientific Communication

Profile Summary
Subject Matter Expertise
Services
Writing Medical Writing, Technical Writing, General Proofreading & Editing
Research Gap Analysis, Scientific and Technical Research, Systematic Literature Review
Consulting Scientific and Technical Consulting
Data & AI Data Visualization
Work Experience

Research Assistant Professor

University of Pittsburgh

January 2022 - Present

Research Instructor

University of Pittsburgh

January 2020 - December 2021

Postdoctoral Scholar

University of Pittsburgh

October 2015 - December 2019

Education

MD, PhD (Neurology)

Southern Medical University

September 2007 - June 2015

Certifications
Publications
PREPRINT
Shanshan Song, Misbah Mehrab, Zohaib Tahir, Kathleen A. Garrison, Stephen Ziskind (2025). Mechanisms and Clinical Applications of Cooling Interventions for Sleep .
Shanshan Song, Muhammad Irfan, Zohaib Tahir, Kathleen Garrison, Stephen Ziskind (2025). Sleep Onset Anxiety: Mechanisms and Evidence-Based Approaches in Clinical Practice .
Shanshan Song, Maham Muneer, Zohaib Tahir, Kathleen A. Garrison, Stephen Ziskind (2025). Circadian-Based Sleep Interventions in Clinical Applications: A Narrative Review .
Shanshan Song, Misbah Mehrab, Zohaib Tahir, Kathleen A Garrison, Stephen Ziskind (2025). Sensory-Based Sleep Interventions: Light, Sound, and Temperature as Therapeutic Tools .
John Paul Bielanin, Shamseldin Ayman Hassan Metwally, Helena C.M. Oft, Satya S. Paruchuri, Lin Lin, Okan Capuk, Nicholas D. Pennock, Shanshan Song, Dandan Sun (2024). NHE1 Protein in Repetitive Mild TBI-Mediated Neuroinflammation and Neurological Function Impairment .
Shamseldin Ayman Hassan Metwally, Satya Siri Paruchuri, Lauren Yu, Okan Capuk, Nicholas Pennock, Dandan Sun, Shanshan Song (2023). Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke .
JOURNAL ARTICLE
John P. Bielanin, Shamseldin A. H. Metwally, Helena C. M. Oft, Satya S. Paruchuri, Lin Lin, Okan Capuk, Nicholas D. Pennock, Shanshan Song, Dandan Sun (2024). NHE1 Protein in Repetitive Mild TBI-Mediated Neuroinflammation and Neurological Function Impairment . Antioxidants.
John P. Bielanin, Shamseldin A. H. Metwally, Helena C. M. Oft, Satya S. Paruchuri, Lin Lin, Okan Capuk, Nicholas D. Pennock, Shanshan Song, Dandan Sun (2024). NHE1 Protein in Repetitive Mild TBI-Mediated Neuroinflammation and Neurological Function Impairment . Antioxidants.
Song, S., Oft, H., Metwally, S., Paruchuri, S., Bielanin, J., Fiesler, V., Sneiderman, C., Kohanbash, G., Sun, D.(2024). Deletion of Slc9a1 in Cx3cr1<sup>+</sup> cells stimulated microglial subcluster CREB1 signaling and microglia-oligodendrocyte crosstalk . Journal of Neuroinflammation. 21. (1).
Shamseldin Ayman Hassan Metwally, Satya Siri Paruchuri, Lauren Yu, Okan Capuk, Nicholas Pennock, Dandan Sun, Shanshan Song (2023). Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke . International Journal of Molecular Sciences.
Shamseldin Ayman Hassan Metwally, Satya Siri Paruchuri, Lauren Yu, Okan Capuk, Nicholas Pennock, Dandan Sun, Shanshan Song (2023). Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke . International Journal of Molecular Sciences.
Metwally, S.A.H., Paruchuri, S.S., Yu, L., Capuk, O., Pennock, N., Sun, D., Song, S.(2023). Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke . International Journal of Molecular Sciences. 24. (17).
Chen, Y., Lin, L., Bhuiyan, M.I.H., He, K., Jha, R., Song, S., Fiesler, V.M., Begum, G., Yin, Y., Sun, D.(2023). Transient ischemic stroke triggers sustained damage of the choroid plexus blood-CSF barrier . Frontiers in Cellular Neuroscience. 17.
Shanshan Song, Lauren Yu, Md Nabiul Hasan, Satya S. Paruchuri, Steven J. Mullett, Mara L. G. Sullivan, Victoria M. Fiesler, Cullen B. Young, Donna B. Stolz, Stacy G. Wendell, et al. (2022). Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice . Communications Biology.
Song, S., Hasan, M.N., Yu, L., Paruchuri, S.S., Bielanin, J.P., Metwally, S., Oft, H.C.M., Fischer, S.G., Fiesler, V.M., Sen, T., et al.(2022). Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury . Journal of Neuroinflammation. 19. (1).
Song, S., Yu, L., Hasan, M.N., Paruchuri, S.S., Mullett, S.J., Sullivan, M.L.G., Fiesler, V.M., Young, C.B., Stolz, D.B., Wendell, S.G., et al.(2022). Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice . Communications Biology. 5. (1).
Lanxin Luo, Shanshan Song, Chibundum C. Ezenwukwa, Shayan Jalali, Baoshan Sun, Dandan Sun(2021). Ion channels and transporters in microglial function in physiology and brain diseases . Neurochemistry International. 142. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 104925. Elsevier {BV}
Lanxin Luo, Shanshan Song, Chibundum C. Ezenwukwa, Shayan Jalali, Baoshan Sun, Dandan Sun (2021). Ion channels and transporters in microglial function in physiology and brain diseases . Neurochemistry International.
Liu, Q., Bhuiyan, M.I.H., Liu, R., Song, S., Begum, G., Young, C.B., Foley, L.M., Chen, F., Hitchens, T.K., Cao, G., et al.(2021). Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function . Journal of Neuroinflammation. 18. (1).
Md Nabiul Hasan, Lanxin Luo, Dawei Ding, Shanshan Song, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Lesley M. Foley, Xiudong Guan, Gary Kohanbash, T. Kevin Hitchens, et al.(2021). Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells . Theranostics. 11. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1295--1309. Ivyspring International Publisher
Hasan, M.N., Luo, L., Ding, D., Song, S., Bhuiyan, M.I.H., Liu, R., Foley, L.M., Guan, X., Kohanbash, G., Kevin Hitchens, T., et al.(2021). Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells . Theranostics. 11. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1295-1309.
Dubaniewicz, M., Eles, J.R., Lam, S., Song, S., Cambi, F., Sun, D., Wellman, S.M., Kozai, T.D.Y.(2021). Inhibition of Na<sup>+</sup>/H<sup>+</sup>exchanger modulates microglial activation and scar formation following microelectrode implantation . Journal of Neural Engineering. 18. (4).
Luo, L., Song, S., Ezenwukwa, C.C., Jalali, S., Sun, B., Sun, D.(2021). Ion channels and transporters in microglial function in physiology and brain diseases . Neurochemistry International. 142.
Song, S., Huang, H., Guan, X., Fiesler, V., Bhuiyan, M.I.H., Liu, R., Jalali, S., Hasan, M.N., Tai, A.K., Chattopadhyay, A., et al.(2021). Activation of endothelial Wnt/β-catenin signaling by protective astrocytes repairs BBB damage in ischemic stroke . Progress in Neurobiology. 199.
Shanshan Song, Huachen Huang, Xiudong Guan, Victoria Fiesler, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Shayan Jalali, Md Nabiul Hasan, Albert K Tai, Ansuman Chattopadhyay, et al.(2020). Activation of endothelial Wnt/β-catenin signaling by protective astrocytes repairs BBB damage in ischemic stroke . Progress in Neurobiology. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 101963. Elsevier {BV}
Song, S., Luo, L., Sun, B., Sun, D.(2020). Roles of glial ion transporters in brain diseases . GLIA. 68. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 472-494.
Shanshan Song, Lanxin Luo, Baoshan Sun, Dandan Sun(2019). Roles of glial ion transporters in brain diseases . Glia. Wiley
Huachen Huang, Mohammad Iqbal H. Bhuiyan, Tong Jiang, Shanshan Song, Sandhya Shankar, Taraneh Taheri, Eric Li, Philipp Schreppel, Michael Hintersteininger, Sung-Sen Yang, et al.(2019). A Novel Na + -K + -Cl − Cotransporter 1 Inhibitor STS66* Reduces Brain Damage in Mice After Ischemic Stroke . Stroke. 50. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1021--1025. Ovid Technologies (Wolters Kluwer Health)
Huang, H., Bhuiyan, M.I.H., Jiang, T., Song, S., Shankar, S., Taheri, T., Li, E., Schreppel, P., Hintersteininger, M., Yang, S.-S., et al.(2019). A Novel Na<sup>+</sup>-K<sup>+</sup>-Cl<sup>-</sup> Cotransporter 1 Inhibitor STS66∗ Reduces Brain Damage in Mice After Ischemic Stroke . Stroke. 50. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1021-1025.
Huachen Huang, Shanshan Song, Suneel Banerjee, Tong Jiang, Jinwei Zhang, Kristopher T. Kahle, Dandan Sun, Zhongling Zhang(2019). The WNK-SPAK/OSR1 Kinases and the Cation-Chloride Cotransporters as Therapeutic Targets for Neurological Diseases . Aging and disease. 10. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 626. Aging and Disease
Huang, H., Song, S., Banerjee, S., Jiang, T., Zhang, J., Kahle, K.T., Sun, D., Zhang, Z.(2019). The WNK-SPAK/OSR1 kinases and the cation-chloride cotransporters as therapeutic targets for neurological diseases . Aging and Disease. 10. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 626-636.
Shanshan Song, Shaoxia Wang, Victoria M. Pigott, Tong Jiang, Lesley M. Foley, Abhishek Mishra, Rachana Nayak, Wen Zhu, Gulnaz Begum, Yejie Shi, et al.(2018). Selective role of Na+/H+ exchanger in Cx3cr1+ microglial activation, white matter demyelination, and post-stroke function recovery . Glia. Wiley
Gulnaz Begum, Shanshan Song, Shaoxia Wang, Hanshu Zhao, Mohammad Iqbal H. Bhuiyan, Eric Li, Rachel Nepomuceno, Qing Ye, Ming Sun, Michael Joseph Calderon, et al. (2018). Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke . Glia.
Begum, G., Song, S., Wang, S., Zhao, H., Bhuiyan, M.I.H., Li, E., Nepomuceno, R., Ye, Q., Sun, M., Calderon, M.J., et al.(2018). Selective knockout of astrocytic Na<sup>+</sup>/H<sup>+</sup> exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke . GLIA. 66. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 126-144.
Song, S., Wang, S., Pigott, V.M., Jiang, T., Foley, L.M., Mishra, A., Nayak, R., Zhu, W., Begum, G., Shi, Y., et al.(2018). Selective role of Na <sup>+</sup> /H <sup>+</sup> exchanger in Cx3cr1 <sup>+</sup> microglial activation, white matter demyelination, and post-stroke function recovery . GLIA. 66. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2279-2298.
Gulnaz Begum, Shanshan Song, Shaoxia Wang, Hanshu Zhao, Mohammad Iqbal H. Bhuiyan, Eric Li, Rachel Nepomuceno, Qing Ye, Ming Sun, Michael Joseph Calderon, et al.(2017). Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke . Glia. 66. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 126--144. Wiley-Blackwell
Bhuiyan, M.I.H., Song, S., Yuan, H., Begum, G., Kofler, J., Kahle, K.T., Yang, S.-S., Lin, S.-H., Alper, S.L., Subramanya, A.R., et al.(2017). WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats . Journal of Cerebral Blood Flow and Metabolism. 37. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2780-2794.
Mohammad Iqbal H Bhuiyan, Shanshan Song, Hui Yuan, Gulnaz Begum, Julia Kofler, Kristopher T Kahle, Sung-Sen Yang, Shih-Hua Lin, Seth L Alper, Arohan R Subramanya, et al.(2016). WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats . Journal of Cerebral Blood Flow & Metabolism. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 0271678X1667536. {SAGE} Publications
Baozhe Jin, Xiaodan Jiang, Haigang Chang, Shanshan Song, Zhongcan Chen, Yaxiao Wang, Lujun Yang, Mouxuan Du, Yiquan Ke, Ruxiang Xu(2014). Transient axonal glycoprotein-1 induces apoptosis-related gene expression without triggering apoptosis in U251 glioma cells . Neural Regeneration Research. 9. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 519. Medknow
Chang, H.G., Song, S.S., Chen, Z.C., Wang, Y.X., Yang, L.J., Du, M.X., Ke, Y.Q., Xu, R.X., Jin, B.Z., Jiang, X.D.(2014). Transient axonal glycoprotein-1 induces apoptosisrelated gene expression without triggering apoptosis in U251 glioma cells . Neural Regeneration Research. 9. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 519-525.