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Hire Dr. Sedigheh T.

United States

USD 80 /hr

PhD Microbiologist, Scientific Writer, Manuscript Editor & Research Consultant

Profile Summary

I am a PhD-trained microbiologist with extensive research experience in microbiology, immunology, and host–microbe interactions. I have more than five years of postdoctoral research experience at internationally recognized institutions including the University of Texas MD Anderson Cancer Center, the University of Pittsburgh School of Medicine, and Henry Ford Health. My research focuses on microbiota–immune system interactions, cancer immunology, probiotics, and molecular microbiology. I have authored and co-authored numerous peer-reviewed scientific publications in international journals and have contributed to multiple research projects investigating microbial pathogenesis, immune regulation, and microbiome-based therapeutic strategies. My work integrates molecular biology, immunology, and microbiome research to understand disease mechanisms and develop innovative therapeutic approaches. My technical expertise includes molecular biology techniques (PCR, RT-qPCR, cloning, primer design), protein analysis (Western blotting, ELISA), cell culture, immunological assays (flow cytometry, CyTOF), and in vivo experimental models and surgical procedures. I also have strong experience in scientific writing, manuscript preparation, literature reviews, and grant-related research documentation. I provide professional services including scientific writing, manuscript editing for journal submission, literature review preparation, research analysis, and consultation on experimental design. I am committed to delivering accurate, high-quality scientific work and clear communication tailored to the needs of research, academic, and biotechnology clients.

Subject Matter Expertise

• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Virology
• ☆ Molecular Biology
• ☆ PCR
• ☆ Cell Biology
• ☆ Cell Culture
• ☆ Clinical Trials
• ☆ Clinical Trial Design
• ☆ Women's Health
• ☆ Breast Cancer
• ☆ Pulmonology/Respiratory Disease
• ☆ Lung Cancer
• ☆ Cancer Research

Services

• Writing
• Research
• Consulting

Writing Technical Writing, General Proofreading & Editing, Translation

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

Work Experience

Research Scientist/Instructor

Henry Ford Health

March 2025 - Present

Postdoctoral Fellow

The University of Texas MD Anderson Cancer Center

July 2023 - January 2025

Postdoctoral Associate (Immunology)

University of Pittsburgh School of Medicine

December 2021 - July 2023

Postdoctoral Researcher

Tongji University

May 2021 - October 2021

Research Assistant

Keyvan Virology Laboratory

September 2012 - July 2019

Education

Doctor of Philosophy (Ph.D.) (Department of Microbiology)

Islamic Azad University Science and Research Branch

September 2015 - October 2018

Master of Science (M.Sc.) (Department of Microbiology)

Qom Branch of the Islamic Azad University

January 2009 - February 2012

Bachelor of Science (B.S) (Department of Microbiology)

Islamic Azad University Farahan Branch

September 2004 - February 2008

Certifications

• PhD

  Islamic Azad university

  December 2018 - Present

Publications

CONFERENCE POSTER

Sedigheh Taghinezhadsaroukalaei, Amirhossein Mohseni, Pamela Beatty, Olivera J Finn (2023). Evidence of immune suppression in PBMC of patients newly diagnosed with ductal carcinoma in situ (DCIS) . Regular and Young Investigator Award Abstracts.

Amir Hossein Mohseni, Sedigheh Taghinezhadsaroukalaei, Pamela Beatty, Olivera J Finn (2023). Gut microbiota and its metabolites are important determinants of the immune response to the MUC1 vaccine in the setting of colon cancer prevention . Regular and Young Investigator Award Abstracts.

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Pamela L. Beatty, Olivera J. Finn (2023). Gut microbiota-derived metabolites as regulators of immunity in pre-cancer . Cancer Research.

JOURNAL ARTICLE

Sedigheh Taghinezhad-S, Amir Hossein Mohseni, Pamela L. Beatty, Leisha A. Emens, Olivera J. Finn (2023). Evidence of immunosuppression in patients with breast ductal carcinoma in situ . Cancer Research.

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Vincenzo Casolaro, Zhongwei Lv, Dan Li (2023). Potential links between the microbiota and T cell immunity determine the tumor cell fate . Cell Death & Disease.

Sedigheh Taghinezhad‐S, Amir Hossein Mohseni, Xiangsheng Fu (2021). Intervention on gut microbiota may change the strategy for management of colorectal cancer . Journal of Gastroenterology and Hepatology.

Edgar Torres-Maravilla, Anne-Sophie Boucard, Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Naima G. Cortes-Perez, Luis G. Bermúdez-Humarán (2021). Role of Gut Microbiota and Probiotics in Colorectal Cancer: Onset and Progression . Microorganisms.

Sedigheh Taghinezhad-S, Amir Hossein Mohseni, Luis G. Bermúdez-Humarán, Vincenzo Casolaro, Naima G. Cortes-Perez, Hossein Keyvani, Jesus Simal-Gandara(2021). Probiotic-Based Vaccines May Provide Effective Protection against COVID-19 Acute Respiratory Disease . Vaccines. 9. (5). p. 466. {MDPI} {AG}

Edgar Torres-Maravilla, Anne-Sophie Boucard, Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Naima G. Cortes-Perez, Luis G. Bermúdez-Humarán (2021). Role of Gut Microbiota and Probiotics in Colorectal Cancer: Onset and Progression . Microorganisms.

Sedigheh Taghinezhad-S, Hossein Keyvani, Luis G. Bermúdez-Humarán, Gilbert G. G. Donders, Xiangsheng Fu, Amir Hossein Mohseni(2021). Twenty years of research on HPV vaccines based on genetically modified lactic acid bacteria: an overview on the gut-vagina axis . Cellular and Molecular Life Sciences. 78. (4). p. 1191--1206. Springer Science and Business Media {LLC}

(2021). Non Detection of HIV-1 Proviral DNA in PBMCs of the Neonates Born to Iranian HIV-infected Mothers in PMTCT Program . Arch Pediatr Infect Dis.

Amir Hossein Mohseni, Vincenzo Casolaro, Luis G. Bermúdez-Humarán, Hossein Keyvani, Sedigheh Taghinezhad-S (2021). Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response . Gut Microbes.

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Zhigang Xu, Xiangsheng Fu(2020). Body fluids may contribute to human-to-human transmission of severe acute respiratory syndrome coronavirus 2: evidence and practical experience . Chinese Medicine. 15. (1). Springer Science and Business Media {LLC}

Peng W, Li H, Xu Y, Yan L, Tang Z, Hossein Mohseni A, Taghinezhad-S S, Tang X, Fu X(2020). Association of <i>Helicobacter bilis</i> Infection with the Development of Colorectal Cancer . Nutrition and cancer.

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Xiangsheng Fu(2020). Gut microbiota-derived metabolites and colorectal cancer: New insights and updates . Microbial Pathogenesis. 149. p. 104569. Elsevier {BV}

(2020). Recombinant Glycoenzyme Production in Gram-Positive Bacteria—An Overview . Trends in Glycoscience and Glycotechnology.

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Hossein Keyvani, Vadood Razavilar(2019). Extracellular overproduction of E7 oncoprotein of Iranian human papillomavirus type 16 by genetically engineered Lactococcus lactis . BMC Biotechnology. 19. (1). Springer Science and Business Media {LLC}

Sedigheh Taghinezhad-S, Amir Hossein Mohseni, Hossein Keyvani, Mohammad Reza Razavi(2019). Phase 1 Safety and Immunogenicity Trial of Recombinant Lactococcus lactis Expressing Human Papillomavirus Type 16 E6 Oncoprotein Vaccine . Molecular Therapy - Methods & Clinical Development. 15. p. 40--51. Elsevier {BV}

Mohseni AH, Taghinezhad-S S, Keyvani H(2019). The First Clinical Use of a Recombinant <i>Lactococcus lactis</i> Expressing Human Papillomavirus Type 16 E7 Oncogene Oral Vaccine: A Phase I Safety and Immunogenicity Trial in Healthy Women Volunteers . Molecular cancer therapeutics.

Reza Aramideh Khouy, Sajad Karampoor, Hossein Keyvani, Farah Bokharaei-Salim, Seyed Hamidreza Monavari, Sedigheh Taghinezhad, Masoud Etemadifar, Maryam Esghaei(2019). The frequency of varicella-zoster virus infection in patients with multiple sclerosis receiving fingolimod . Journal of Neuroimmunology. 328. p. 94--97. Elsevier {BV}

Sedigheh Taghinezhad-S, Amir Hossein Mohseni, Hossein Keyvani, Vadood Razavilar(2019). Protection against human papillomavirus type 16-induced tumors in C57BL/6 mice by mucosal vaccination with Lactococcus lactis NZ9000 expressing E6 oncoprotein . Microbial Pathogenesis. 126. p. 149--156. Elsevier {BV}

Aramideh Khouy, R., Karampoor, S., Keyvani, H., Bokharaei-Salim, F., Monavari, S.H., Taghinezhad, S., Etemadifar, M., Esghaei, M.(2019). The frequency of varicella-zoster virus infection in patients with multiple sclerosis receiving fingolimod . Journal of Neuroimmunology. 328. p. 94-97.

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Hossein Keyvani, Narges Ghobadi(2018). Comparison of Acyclovir and Multistrain Lactobacillus brevis in Women with Recurrent Genital Herpes Infections: a Double-Blind, Randomized, Controlled Study . Probiotics and Antimicrobial Proteins. Springer Nature

Sedigheh Taghinezhad-S, Vadood Razavilar, Hossein Keyvani, Mohammad Reza Razavi, Taher Nejadsattari(2018). Extracellular overproduction of recombinant Iranian HPV-16 E6 oncoprotein in Lactococcus lactis using the NICE system . Future Virology. 13. (10). p. 697--710. Future Medicine Ltd

Taghinezhad-S, S., Razavilar, V., Keyvani, H., Razavi, M.R., Nejadsattari, T.(2018). Extracellular overproduction of recombinant Iranian HPV-16 E6 oncoprotein in Lactococcus lactis using the NICE system . Future Virology. 13. (10). p. 697-710.

Taghinezhad-S, S., Mohseni, A.H., Keyvani, H., Ghobadi, N.(2018). Molecular screening and single nucleotide polymorphism typing of molluscum contagiosum virus (MCV) from genital specimens, between 2012 and 2015 . Iranian Biomedical Journal. 22. (2). p. 129-133.

Sedigheh Taghinezhad-S, Vadood Razavilar, Hossein Keyvani, Mohammad Reza Razavi, Taher Nejadsattari(2017). Codon optimization of Iranian human papillomavirus Type 16 E6 oncogene for Lactococcus lactis subsp. cremoris MG1363 . Future Virology. 12. (9). p. 499--511. Future Medicine Ltd

Mohseni AH, Soleimani M, Majidzadeh-A K, Taghinezhad-S S, Keyvani H(2017). Active Expression of Human Tissue Plasminogen Activator (t-PA) c-DNA from Pulmonary Metastases in the Methylotrophic Yeast Pichia Pastoris KM71H Strain . Asian Pacific journal of cancer prevention : APJCP.

Taghinezhad-S S, Mohseni AH, Keyvani H, Ghobadi N(2017). Molecular Screening and Single Nucleotide Polymorphism Typing of Molluscum Contagiosum Virus (MCV) from Genital Specimens, between 2012 and 2015 . Iranian biomedical journal.

Mohseni, A.H., Soleimani, M., Majidzadeh-A, K., Taghinezhad-S, S., Keyvani, H.(2017). Active expression of human tissue plasminogen activator (t-PA) c-DNA from pulmonary metastases in the methylotrophic yeast Pichia pastoris KM71H strain . Asian Pacific Journal of Cancer Prevention. 18. (8). p. 2249-2254.

Taghinezhad-S, S., Razavilar, V., Keyvani, H., Razavi, M.R., Nejadsattari, T.(2017). Codon optimization of Iranian human papillomavirus Type 16 E6 oncogene for Lactococcus lactis subsp. cremoris MG1363 . Future Virology. 12. (9). p. 499-511.

Sedigheh Taghinezhad Saroukalaei, Hossein Keyvani, Amir Hossein Mohseni(2016). Assessment of the Human Cytomegalovirus UL97 Gene for Identification of Resistance to Ganciclovir in Iranian Immunosuppressed Patients . Jundishapur Journal of Microbiology. 9. (5). Kowsar Medical Institute

Sedigheh Taghinezhad Saroukalaei, Farzin Sadeghi, Mostafa Salehi-Vaziri, Seyed Mohammad Ghodsi, Ahad Alizadeh, Farah Bokharaei-Salim, Mohammadhossein Mirbolouk, Seyed Hamidreza Monavari, Hossein Keyvani(2014). Prevalence of JC polyomavirus large T antigen sequences among Iranian patients with central nervous system tumors . Archives of Virology. 160. (1). p. 61--68. Springer Nature

PREPRINT

Sedigheh Taghinezhad-S, Amir Hossein Mohseni, Wen Jiang, Vincenzo Casolaro, Luis G. Berm&#250;dez-Humar&#225;n, Florencia McAllister, Zhongwei Lv, Dan Li (2023). Host-microbe interactions mediate doramectin-promoted metabolic reprogramming of CD8+T-cells and amplify antitumor immunity .

Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Bing Su, Feng Wang (2020). Inferring MHC interacting SARS-CoV-2 epitopes recognized by TCRs towards designing T cell-based vaccines .