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Hire Dr. Sarah W.

United Kingdom

USD 80 /hr

Neuroscience and psychology background | Expertise in biomarkers of dementia, and drug development for rare CNS diseases

Profile Summary

Neuroscience, neuroimaging & psychology research background (BSc, MSc, PhD). Most recent industry experience includes drug development for rare CNS diseases. My most recent postdoctoral position was as a Biomarker Team Leader at the University of Oxford, in the Translational Neuroscience and Dementia Research Team. Here I was responsible for the day to day management of several projects, most of which were focused upon discovering, replicating and validating biomarkers for Alzheimer's disease. I was involved in dementia research for over 10 years. I am proficient in a number of laboratory skills (incl. ELISA, Meso Scale Discovery, Luminex xMAP, SOMAscan, blood processing, PBMC Prep, LC-MS/MS) and data analysis techniques and softwares (incl. R, SPSS, SigmaPlot, Excel). I am used to working with big data and analysing data from large multi-cohort datasets. I have experience in project management, meeting co-ordination, medical writing and presentations. I have a fairly varied scientific background, having degrees in Psychological Medicine (PhD), Cognitive Brain Imaging (MSc) and Psychology (BSc). I am a quick learner and enjoy learning new areas of science. I am also a good problem solver and have good attention to detail.

Subject Matter Expertise

• ★ Biomarkers
• ★ Drug Development
• ★ Alzheimer's Disease
• ☆ Proteomics
• ☆ Neuroscience
• ☆ Cognitive Neuroscience
• ☆ Neuropsychology
• ☆ Psychology
• ☆ SPSS
• ☆ Excel
• ☆ Small Molecule Drug Development
• ☆ Clinical Trials
• ☆ Medical Imaging/Radiology
• ☆ Non-Alzheimer's Dementia
• ☆ Neuropsychiatry
• ☆ Geriatric Psychiatry

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Medical Writing, Technical Writing, Business & Legal Writing, Copywriting, Creative Writing, Newswriting, Audio Transcription, General Proofreading & Editing

Research Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

Work Experience

Research Director

ConSynance Therapeutics

June 2020 - Present

Biomarker Team Leader

University of Oxford

October 2017 - October 2018

Postdoctoral Scientist

University of Oxford

September 2014 - October 2017

Tutor for the Final Honour School of Medical Sciences, Experimental Psychology and Medicine

University of Oxford

September 2015 - September 2017

Research Worker

King's College London

October 2010 - February 2011

Education

PhD Psychological Medicine

King's College London

February 2011 - April 2014

MSc Cognitive Brain Imaging

University of Manchester

September 2009 - September 2010

BSc Psychology

University of Manchester

September 2006 - September 2009

Certifications

• Clinical Development 101: General Principles

  Biotech Primer

  July 2023 - Present

Publications

JOURNAL ARTICLE

(2018). Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result . Frontiers in aging neuroscience.

(2017). The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology . Alzheimer's research & therapy.

(2015). Blood-Based Proteomic Biomarkers of Alzheimer's Disease Pathology . Frontiers in neurology.

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort . Journal of Alzheimer's disease : JAD.

A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort . Alzheimer's & dementia (New York, N. Y.).

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum . Alzheimer's & dementia : the journal of the Alzheimer's Association.

A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication . Journal of Alzheimer's disease : JAD.

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay . Alzheimer's & dementia : the journal of the Alzheimer's Association.

Blood protein predictors of brain amyloid for enrichment in clinical trials? . Alzheimer's & dementia (Amsterdam, Netherlands).

Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly . Journal of Alzheimer's disease : JAD.

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort . Alzheimer's & dementia : the journal of the Alzheimer's Association.

Inflammatory biomarkers in Alzheimer's disease plasma . Alzheimer's & dementia : the journal of the Alzheimer's Association.

Evaluation of a calibrated (18)F-FDG PET score as a biomarker for progression in Alzheimer disease and mild cognitive impairment . Journal of nuclear medicine : official publication, Society of Nuclear Medicine.