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Scientific Writer with 10+ years experience in Glycosciences, Cancer Biology, Enzyme Kinetics

Profile Summary

• Cell and Molecular Biologist with a vast experience in Glycosciences, Cancer Biology, Enzyme Kinetics and Enzymatic Biochemical Characterization. • Postdoc from CSIR-CCMB, Nebraska Medical Center and doctorate from SUNY Buffalo, B.Tech from Indian Institute of Technology. • Research experience in the role of glycosylation on inflammation, cancer progression, cancer metastasis, cancer biomarker discovery, metabolomics, synthetic glycomics, etc. • Experience as a scientist in biopharma companies specializing on cell culture, extracellular monoclonal antibodies generation, analytical sciences, HPLC separation of Low Molecular Weight Heparins, etc. • Having completed engineering from one of the best institutes across the world, I am confident in using any latest technology with ease and can work around it with ease. What can I offer you? • Scientific, Medical and Blog Writing, Editing • Science Project Management • Deep Research Analysis, Grant Editing, Proposal Editing • Science Policy Making Science Story Samples: https://indiabioscience.org/news/2023/mosquitoes-on-the-hunt-the-role-of-olfaction-in-finding-human-hosts Blog Samples: https://www.rohiteshgupta.com/blog

Subject Matter Expertise

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Enzyme Activity Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Omics
• ☆ Metabolomics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Gene Expression Analysis
• ☆ Plasmid DNA
• ☆ Monoclonal Antibody Production
• ☆ Biomarker Discovery
• ☆ Immunohistochemistry
• ☆ Drug Development
• ☆ Preclinical Research
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Carcinogenesis

Services

• Writing
• Research
• Consulting
• Product Development

Writing Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing

Research Fact Checking, Gap Analysis, Gray Literature Search, Scientific and Technical Research

Consulting Scientific and Technical Consulting

Product Development Concept Development

Work Experience

Scientific Advisor

Freelancer

June 2023 - Present

Senior Research Associate

CSIR-Center for Cellular and Molecular Biology

September 2020 - June 2023

Postdoctrate

University of Nebraska Medical Center-Nebraska Medicine

February 2018 - January 2020

Scientist IV

Aurobindo Pharma Ltd

July 2016 - December 2017

Senior Scientist / Group Manager

Biological E. Limited

December 2015 - June 2016

Education

PhD

University at Buffalo

August 2010 - September 2015

Bachelor of Technology

Indian Institute of Technology Kanpur

July 2004 - April 2008

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Gupta R, Ponangi R, Indresh KG (2023). Role of glycosylation in breast cancer progression and metastasis: implications for miRNA, EMT and multi-drug resistance . Glycobiology.

Lakshmanan, I., Chaudhary, S., Vengoji, R., Seshacharyulu, P., Rachagani, S., Carmicheal, J., Jahan, R., Atri, P., Chirravuri-Venkata, R., Gupta, R., et al.(2021). ST6GalNAc-I promotes lung cancer metastasis by altering MUC5AC sialylation . Molecular Oncology. 15. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1866-1881.

Nimmakayala, R.K., Leon, F., Rachagani, S., Rauth, S., Nallasamy, P., Marimuthu, S., Shailendra, G.K., Chhonker, Y.S., Chugh, S., Chirravuri, R., et al.(2021). Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma . Oncogene. 40. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 215-231.

Gupta, R., Leon, F., Thompson, C.M., Nimmakayala, R., Karmakar, S., Nallasamy, P., Chugh, S., Prajapati, D.R., Rachagani, S., Kumar, S., et al.(2020). Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis . British Journal of Cancer. 122. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1661-1672.

Karmakar, S., Rauth, S., Nallasamy, P., Perumal, N., Nimmakayala, R.K., Leon, F., Gupta, R., Barkeer, S., Venkata, R.C., Raman, V., et al.(2020). RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3 . Gastroenterology. 159. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1898-1915.e6.

Gupta, R., Leon, F., Thompson, C.M., Nimmakayala, R., Karmakar, S., Nallasamy, P., Chugh, S., Prajapati, D.R., Rachagani, S., Kumar, S., et al.(2020). Correction: Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis (British Journal of Cancer, (2020), 122, 11, (1661-1672), 10.1038/s41416-020-0772-3) . British Journal of Cancer. 122. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1726.

Gupta, R., Leon, F., Rauth, S., Batra, S.K., Ponnusamy, M.P.(2020). A Systematic Review on the Implications of O-linked Glycan Branching and Truncating Enzymes on Cancer Progression and Metastasis . Cells. 9. (2).

Del Solar, V., Gupta, R., Zhou, Y., Pawlowski, G., Matta, K.L., Neelamegham, S.(2020). Robustness in glycosylation systems: Effect of modified monosaccharides, acceptor decoys and azido sugars on cellular nucleotide-sugar levels and pattern of N-linked glycosylation . Molecular Omics. 16. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 377-386.

Gupta, R., Ponnusamy, M.P.(2018). Analysis of sulfates on low molecular weight heparin using mass spectrometry: structural characterization of enoxaparin . Expert Review of Proteomics. 15. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 503-513.

Gupta, R., Matta, K.L., Neelamegham, S.(2016). A systematic analysis of acceptor specificity and reaction kinetics of five human α(2,3)sialyltransferases: Product inhibition studies illustrate reaction mechanism for ST3Gal-I . Biochemical and Biophysical Research Communications. 469. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 606-612.

Buffone Jr., A., Mondal, N., Gupta, R., McHugh, K.P., Lau, J.T.Y., Neelamegham, S.(2013). Silencing α1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during e-selectin-mediated cell adhesion . Journal of Biological Chemistry. 288. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1620-1633.

Lo, C.Y., Antonopoulos, A., Gupta, R., Qu, J., Dell, A., Haslam, S.M., Neelamegham, S.(2013). Competition between core-2 GlcNAc-transferase and ST6GalNAc-transferase regulates the synthesis of the leukocyte selectin ligand on human P-selectin glycoprotein ligand-1 . Journal of Biological Chemistry. 288. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13974-13987.