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Hire Dr. Ravi D.

United States

Profile Summary

Biomedical Scientist with 20+ years of research experience 27 publications and 50+ abstracts (basic, clinical, translational research) in the context of biological mechanisms of cancer, response to therapy in hematological malignancies; lymphoma and solid tumors; head & neck, lung, breast and melanoma cancers, through the application of molecular biology and BigData/Systems Biology concepts. (for complete list of publication and profile https://www.linkedin.com/in/ravidashnamoorthy)

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Systems Biology
• ☆ Oncology
• ☆ Cancer Research

Services

• Writing
• Research
• Consulting
• Product Development

Writing Clinical Trial Documentation, Technical Writing

Research Feasibility Study

Consulting Scientific and Technical Consulting

Product Development Formulation

Work Experience

Adjunct Assistant Professor

Rutgers University

March 2018 - Present

Research Assistant Professor

Tufts University School of Medicine

January 2014 - December 2017

Research Associate

Tufts Medical Center

August 2013 - December 2017

Assistant Professor of Medicine, Research

UMass Memorial Medical Center University Campus

February 2012 - July 2013

Instructor

UMass Memorial Medical Center University Campus

July 2011 - January 2012

Education

PhD Biochemistry (Regional Cancer Center, Trivandrum)

Mahatma Gandhi University

January 1995 - October 2000

M.Sc Medical Biochemistry (Biochemistry)

Jawaharlal Institute of Post Graduate Medical Education

July 1991 - June 1994

B.Sc Biochemistry (Biochemistry)

University of Madras

August 1988 - June 1991

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2019). Interaction kinetics with transcriptomic and secretory responses of CD19-CAR natural killer-cell therapy in CD20 resistant non-hodgkin lymphoma . Leukemia.

(2019). Combinatorial ixazomib and belinostat therapy induces NFE2L2-dependent apoptosis in Hodgkin and T-cell lymphoma . British journal of haematology.

(2019). The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma . Oncotarget.

(2019). Microfluidic assembly of hydrogel-based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release. J Control Release.

(2018). Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel. Oncotarget.

(2018). Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel . Oncotarget.

(2017). Dynamic Analysis of Human Natural Killer Cell Response at Single-Cell Resolution in B-Cell Non-Hodgkin Lymphoma. Front Immunol.

(2016). Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma. Cancer Research.

(2016). Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human . PLoS One.

Ravi, D., Bhalla, S., Gartenhaus, R.B., Crombie, J., Kandela, I., Sharma, J., Mazar, A., Evens, A.M.(2014). The novel organic arsenical darinaparsin induces MAPK-mediated and SHP1-dependent cell death in T-cell lymphoma and hodgkin lymphoma cells and human xenograft models . Clinical Cancer Research. 20. (23). p. 6023-6033.

Doderer, M.S., Anguiano, Z., Suresh, U., Dashnamoorthy, R., Bishop, A.J., Chen, Y.(2012). Pathway Distiller - multisource biological pathway consolidation . BMC genomics. 13 Suppl 6.

Ravi, D., Chen, Y., Karia, B., Brown, A., Gu, T.T., Li, J., Carey, M.S., Hennessy, B.T., Bishop, A.J.R.(2011). 14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis . PLoS ONE. 6. (1).

Wiles, A.M., Doderer, M., Ruan, J., Gu, T.-T., Ravi, D., Blackman, B., Bishop, A.J.R.(2010). Building and analyzing protein interactome networks by cross-species comparisons . BMC Systems Biology. 4.

Ravi, D., Wiles, A.M., Bhavani, S., Ruan, J., Leder, P., Bishop, A.J.R.(2009). A network of conserved damage survival pathways revealed by a genomic RNAi screen . PLoS Genetics. 5. (6).

Ravi, D., Muniyappa, H., Das, K.C.(2008). Caffeine inhibits UV-mediated NF-κB activation in A2058 melanoma cells: An ATM-PKCδ-p38 MAPK-dependent mechanism . Molecular and Cellular Biochemistry. 308. (1-2). p. 193-200.

Wiles, A.M., Ravi, D., Bhavani, S., Bishop, A.J.R.(2008). An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme . Journal of Biomolecular Screening. 13. (8). p. 777-784.

Ravi, D., Muniyappa, H., Das, K.C.(2005). Endogenous thioredoxin is required for redox cycling of anthracyclines and p53-dependent apoptosis in cancer cells . Journal of Biological Chemistry. 280. (48). p. 40084-40096.

Das, K.C., Dashnamoorthy, R.(2004). Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites . American Journal of Physiology - Lung Cellular and Molecular Physiology. 286. (1 30-1).

Das, K.C., Ravi, D.(2004). Altered Expression of Cyclins and Cdks in Premature Infant Baboon Model of Bronchopulmonary Dysplasia . Antioxidants and Redox Signaling. 6. (1). p. 117-127.

Das, K.C., Ravi, D., Holland, W.(2004). Increased Apoptosis and Expression of p21 and p53 in Premature Infant Baboon Model of Bronchopulmonary Dysplasia . Antioxidants and Redox Signaling. 6. (1). p. 109-116.

Ravi, D., Das, K.C.(2004). Redox-cycling of anthracyclines by thioredoxin system: Increased superoxide generation and DNA damage . Cancer Chemotherapy and Pharmacology. 54. (5). p. 449-458.

Ravi, D., Ramadas, K., Mathew, B.S., Panikkar, K.R., Nair, M.K., Pillai, M.R.(2001). Apoptosis, angiogenesis and proliferation: Trifunctional measure of tumour response to radiotherapy for oral cancer . Oral Oncology. 37. (2). p. 164-171.

Ravi, D., Panikkar, K.R., Krishnan Nair, M., Radhakrishna Pillai, M.(2000). Apoptosis: Future directions in cancer therapy . National Medical Journal of India. 13. (2). p. 71-78.

Ravi, D., Ramadas, K., Mathew, B.S., Nalinakumarit, K.R., Nair, M.K., Pillai, M.R.(1999). De novo programmed cell death in oral cancer . Histopathology. 34. (3). p. 241-249.

Ravi, D., Ramadas, K., Mathew, B.S., Nalinakumari, K.R., Nair, M.K., Pillai, M.R.(1998). Angiogenesis during tumor progression in the oral cavity is related to reduced apoptosis and high tumor cell proliferation . Oral Oncology. 34. (6). p. 543-548.

Pillai, M.R., Ravi, D., Nair, M.K.(1997). Chemoprevention of oral cancer: the need for effective biological monitoring . Singapore dental journal. 22. (1). p. 6-12.

Ravi, D., Nalinakumari, K.R., Rajaram, R.S., Nair, M.K., Pillai, M.R.(1996). Expression of programmed cell death regulatory p53 and bcl-2 proteins in oral lesions . Cancer Letters. 105. (2). p. 139-146.

Lakshmi Kesari, A., Radhakrishnan, R., Bhanumathi, A., Ravi, D., Srinivas, G., Krishnan Nair, M., Radhakrishna Pillai, M.(1996). Expression of epidermal and transforming growth factors in pancreatic cancer . Oncology Reports. 3. (5). p. 963-966.

BOOK

Ravi, D., Bishop, A.J.R.(2012). Identification of genes required for damage survival using a cell-based RNAi screen against the drosophila genome . Methods in Molecular Biology. 920. p. 9-26.

CONFERENCE PAPER

Doderer, M.S., Anguiano, Z., Suresh, U., Dashnamoorthy, R., Bishop, A.J.R., Chen, Y.(2011). Multisource biological pathway consolidation . Proceedings - IEEE International Workshop on Genomic Signal Processing and Statistics. p. 74-77.