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Hire Dr. Pierre-François R.
France
USD 30 /hr
Ph.D in Genetics & Bioinformatics, studying the interplay between metabolism and the epigenome in senescence and aging.
Profile Summary
Subject Matter Expertise
Services
Writing
Technical Writing
Research
Market Research
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis,
Data Visualization,
Big Data Analytics,
Data Mining,
Data Processing,
Data Insights
Work Experience
Postdoctoral Scientist
Institut de Recherche en Cancérologie de Montpellier - Inserm U1194
February 2021 - Present
Institut de Recherche en Cancérologie de Montpellier
February 2021 - Present 
Postdoctoral Scientist
Johnson and Johnson
September 2019 - February 2022
Postdoctoral Scientist
Institut Pasteur - Inserm U993
March 2015 - September 2019
Education
PhD in Genetics & Bio-informatics
Institut Agro - Rennes
September 2011 - December 2014
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Takahiro Sato, Janet Nikolovski, Russell Gould, Imane Lboukili, Pierre‐Francois Roux, Gabriel Al‐Ghalith, Jeremy Orie, Richard Insel, Georgios Stamatas(2023). Skin surface biomarkers are associated with future development of atopic dermatitis in children with family history of allergic disease . Skin Research and Technology. 29. (10). Wiley
Georgios Stamatas, Pierre‐Francois Roux, Elise Boireau‐Adamezyk, Imane Lboukili, Thierry Oddos(2023). Skin maturation from birth to 10 years of age: Structure, function, composition and microbiome . Experimental Dermatology. 32. (9). p. 1420--1429. Wiley
Ricardo Iván Martínez-Zamudio, Alketa Stefa, José Américo Nabuco Leva Ferreira Freitas, Themistoklis Vasilopoulos, Mark Simpson, Gregory Doré, Pierre-François Roux, Mark A. Galan, Ravi J. Chokshi, Oliver Bischof, et al.(2023). Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars . Cell Genomics. p. 100293. Elsevier {BV}
Pierre-François Roux, Thierry Oddos, Georgios Stamatas(2022). Deciphering the Role of Skin Surface Microbiome in Skin Health: An Integrative Multiomics Approach Reveals Three Distinct Metabolite‒Microbe Clusters . Journal of Investigative Dermatology. Elsevier {BV}
Roux, P.-F., Oddos, T., Stamatas, G.(2022). Deciphering the Role of Skin Surface Microbiome in Skin Health: An Integrative Multiomics Approach Reveals Three Distinct Metabolite‒Microbe Clusters . Journal of Investigative Dermatology. 142. (2). p. 469-479.e5.
Thomas Ondet, Pierre-François Roux, Mario Monshouwer, Georgios N. Stamatas(2021). Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses . JID Innovations. 1. (2). p. 100009. Elsevier {BV}
Mangez, C., Roux, P.-F., Stamatas, G., Oddos, T., Brun, C.(2021). An integrative multi-omic analysis reveals a major metabolic rewiring between baby foreskin keratinocytes and adult female abdominal keratinocytes . Experimental Dermatology.
Ignacio López, Eleftheria Chalatsi, Saskia I. J. Ellenbroek, Alexandra Andrieux, Pierre-François Roux, Juan P. Cerapio, Grégory Jouvion, Jacco van Rheenen, Jacob-S. Seeler, Anne Dejean(2020). An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency . Oncogene. 39. (43). p. 6692--6703. Springer Science and Business Media {LLC}
Martínez-Zamudio, R.I., Roux, P.-F., de Freitas, J.A.N.L.F., Robinson, L., Doré, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C.A., et al.(2020). AP-1 imprints a reversible transcriptional programme of senescent cells . Nature Cell Biology. 22. (7). p. 842-855.
López, I., Chalatsi, E., Ellenbroek, S.I.J., Andrieux, A., Roux, P.-F., Cerapio, J.P., Jouvion, G., van Rheenen, J., Seeler, J.-S., Dejean, A.(2020). An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency . Oncogene. 39. (43). p. 6692-6703.
Martínez-Zamudio, R.I., Roux, P.-F., de Freitas, J.A.N.L.F., Robinson, L., Doré, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C.A., et al.(2020). Author Correction: AP-1 imprints a reversible transcriptional programme of senescent cells (Nature Cell Biology, (2020), 22, 7, (842-855), 10.1038/s41556-020-0529-5) . Nature Cell Biology. 22. (10). p. 1286-1288.
Marco Seehawer, Florian Heinzmann, Luana D’Artista, Jule Harbig, Pierre-François Roux, Lisa Hoenicke, Hien Dang, Sabrina Klotz, Lucas Robinson, Grégory Doré, et al.(2018). Necroptosis microenvironment directs lineage commitment in liver cancer . Nature. Springer Nature America, Inc
Desert C, Baéza E, Aite M, Boutin M, Le Cam A, Montfort J, Houee-Bigot M, Blum Y, Roux PF, Hennequet-Antier C, et al.(2018). Multi-tissue transcriptomic study reveals the main role of liver in the chicken adaptive response to a switch in dietary energy source through the transcriptional regulation of lipogenesis . BMC genomics.
Desert, C., Baéza, E., Aite, M., Boutin, M., Le Cam, A., Montfort, J., Houee-Bigot, M., Blum, Y., Roux, P.F., Hennequet-Antier, C., et al.(2018). Multi-tissue transcriptomic study reveals the main role of liver in the chicken adaptive response to a switch in dietary energy source through the transcriptional regulation of lipogenesis . BMC Genomics. 19. (1).
Seehawer, M., Heinzmann, F., D’Artista, L., Harbig, J., Roux, P.-F., Hoenicke, L., Dang, H., Klotz, S., Robinson, L., Doré, G., et al.(2018). Erratum to: Necroptosis microenvironment directs lineage commitment in liver cancer (Nature, (2018), 562, 7725, (69-75), 10.1038/s41586-018-0519-y) . Nature. 564. (7735). p. E9.
Seehawer, M., Heinzmann, F., D’Artista, L., Harbig, J., Roux, P.-F., Hoenicke, L., Dang, H., Klotz, S., Robinson, L., Doré, G., et al.(2018). Necroptosis microenvironment directs lineage commitment in liver cancer . Nature. 562. (7725). p. 69-75.
(2017). SnapShot: Cellular Senescence Pathways . Cell.
(2017). SnapShot: Cellular Senescence in Pathophysiology . Cell.
Eduardo Fernandez-Rebollo, Birgit Mentrup, Regina Ebert, Julia Franzen, Giulio Abagnale, Torsten Sieben, Alina Ostrowska, Per Hoffmann, Pierre-François Roux, Björn Rath, et al. (2017). Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells . Scientific Reports.
Contrepois, K., Coudereau, C., Benayoun, B.A., Schuler, N., Roux, P.-F., Bischof, O., Courbeyrette, R., Carvalho, C., Thuret, J.-Y., Ma, Z., et al.(2017). Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression . Nature Communications. 8.
Fernandez-Rebollo, E., Mentrup, B., Ebert, R., Franzen, J., Abagnale, G., Sieben, T., Ostrowska, A., Hoffmann, P., Roux, P.-F., Rath, B., et al.(2017). Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells . Scientific Reports. 7. (1).
Martínez-Zamudio, R.I., Robinson, L., Roux, P.-F., Bischof, O.(2017). SnapShot: Cellular Senescence in Pathophysiology . Cell. 170. (5). p. 1044-1044.e1.
Martínez-Zamudio, R.I., Robinson, L., Roux, P.-F., Bischof, O.(2017). SnapShot: Cellular Senescence Pathways . Cell. 170. (4). p. 816-816.e1.
Pierre-François Roux, Laure Frésard, Morgane Boutin, Sophie Leroux, Christophe Klopp, Anis Djari, Diane Esquerré, Pascal GP Martin, Tatiana Zerjal, David Gourichon, et al.(2016). The Extent of mRNA Editing Is Limited in Chicken Liver and Adipose, but Impacted by Tissular Context, Genotype, Age, and Feeding as Exemplified with a Conserved Edited Site in COG3 . G3: Genes|Genomes|Genetics. 6. (2). p. 321--335. Genetics Society of America
Roux, P.-F., Frésard, L., Boutin, M., Leroux, S., Klopp, C., Djari, A., Esquerré, D., Martin, P.G.P., Zerjal, T., Gourichon, D., et al.(2016). The extent of mRNA editing is limited in chicken liver and adipose, but impacted by tissular context, genotype, age, and feeding as exemplified with a conserved edited site in COG3 . G3: Genes, Genomes, Genetics. 6. (2). p. 321-335.
Désert, C., Merlot, E., Zerjal, T., Bed'hom, B., Härtle, S., Le Cam, A., Roux, P.-F., Baeza, E., Gondret, F., Duclos, M.J., et al.(2016). Transcriptomes of whole blood and PBMC in chickens . Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 20. p. 1-9.
Pierre-François Roux, Simon Boitard, Yuna Blum, Brian Parks, Alexandra Montagner, Etienne Mouisel, Anis Djari, Diane Esquerré, Colette Désert, Morgane Boutin, et al.(2015). Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation . G3: Genes|Genomes|Genetics. 5. (4). p. 517--529. Genetics Society of America
Roux, P.F., Marthey, S., Djari, A., Moroldo, M., Esquerré, D., Estellé, J., Klopp, C., Lagarrigue, S., Demeure, O.(2015). Comparison of whole-genome (13X) and capture (87X) resequencing methods for SNP and genotype callings . Animal Genetics. 46. (1). p. 82-86.
Frésard, L., Leroux, S., Roux, P.-F., Klopp, C., Fabre, S., Esquerré, D., Dehais, P., Djari, A., Gourichon, D., Lagarrigue, S., et al.(2015). Genome-wide characterization of RNA editing in chicken embryos reveals common features among vertebrates . PLoS ONE. 10. (5).
Schmid, M., Smith, J., Burt, D.W., Aken, B.L., Antin, P.B., Archibald, A.L., Ashwell, C., Blackshear, P.J., Boschiero, C., Brown, C.T., et al.(2015). Third Report on Chicken Genes and Chromosomes 2015: . Cytogenetic and Genome Research. 145. (2). p. 78-179.
Roux, P.-F., Boitard, S., Blum, Y., Parks, B., Montagner, A., Mouisel, E., Djari, A., Esquerré, D., Désert, C., Boutin, M., et al.(2015). Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation . G3: Genes, Genomes, Genetics. 5. (4). p. 517-529.
Roux, P.-F., Boutin, M., Désert, C., Djari, A., Esquerré, D., Klopp, C., Lagarrigue, S., Demeure, O.(2014). Re-sequencing data for refining candidate genes and polymorphisms in QTL regions affecting adiposity in chicken . PLoS ONE. 9. (10).
Lagarrigue, S., Martin, L., Hormozdiari, F., Roux, P., Pan, C., van Nas, A., Demeure, O., Cantor, R., Ghazalpour, A., Eskin, E., et al.(2013). Analysis of allele-specific expression in mouse liver by RNA-seq: A comparison with Cis-eQTL identified using genetic linkage . Genetics. 195. (3). p. 1157-1166.
Simonin-Le Jeune, K., Le Jeune, A., Jouneau, S., Belleguic, C., Roux, P.-F., Jaguin, M., Dimanche-Boitre, M.-T., Lecureur, V., Leclercq, C., Desrues, B., et al.(2013). Impaired Functions of Macrophage from Cystic Fibrosis Patients: CD11b, TLR-5 Decrease and sCD14, Inflammatory Cytokines Increase . PLoS ONE. 8. (9).
NEWSPAPER ARTICLE
Ricardo Iván Martínez-Zamudio, Alketa Stefa, José Américo Nabuco Leva Ferreira Freitas, Themistoklis Vasilopoulos, Mark Simpson, Gregory Doré, Pierre-François Roux, Mark A. Galan, Ravi J. Chokshi, Oliver Bischof, et al.(2023). Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars . Cell Genomics. 3. (4). p. 100293. Elsevier {BV}
Claire Mangez and Pierre-Fran{\c{c}}ois Roux and Georgios Stamatas and Thierry Oddos and C{\'{e}}cilia Brun(2021). An integrative multi‐omic analysis reveals a major metabolic rewiring between baby foreskin keratinocytes and adult female abdominal keratinocytes . Experimental Dermatology. Wiley
Pierre-Fran{\c{c}}ois Roux and Thierry Oddos and Georgios Stamatas(2021). Deciphering the role of skin surface microbiome in skin health: an integrative multi-omics approach reveals three distinct metabolite-microbe clusters . Journal of Investigative Dermatology. Elsevier {BV}
Thomas Ondet and Pierre-Fran{\c{c}}ois Roux and Mario Monshouwer and Georgios N. Stamatas(2021). Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses . JID Innovations. 1. (2). p. 100009. Elsevier {BV}
Ignacio L{\'{o}}pez and Eleftheria Chalatsi and Saskia I. J. Ellenbroek and Alexandra Andrieux and Pierre-Fran{\c{c}}ois Roux and Juan P. Cerapio and Gr{\'{e}}gory Jouvion and Jacco van Rheenen and Jacob-S. Seeler and Anne Dejean(2020). An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency . Oncogene. 39. (43). p. 6692--6703. Springer Science and Business Media {LLC}
(2020). AP-1 imprints a reversible transcriptional programme of senescent cells . Nature Cell Biology.
Marco Seehawer and Florian Heinzmann and Luana D'Artista and Jule Harbig and Pierre-Fran{\c{c}}ois Roux and Lisa Hoenicke and Hien Dang and Sabrina Klotz and Lucas Robinson and Gr{\'{e}}gory Dor{\'{e}} and Nir Rozenblum and Tae-Won Kang and Rishabh Chawla and Thorsten Buch and Mihael Vucur and Mareike Roth and Johannes Zuber and Tom Luedde and Bence Sipos and Thomas Longerich and Mathias Heikenwälder and Xin Wei Wang and Oliver Bischof and Lars Zender(2018). Necroptosis microenvironment directs lineage commitment in liver cancer . Nature. Springer Nature America, Inc
Pierre-Fran{\c{c}}ois Roux and Laure Fr{\'{e}}sard and Morgane Boutin and Sophie Leroux and Christophe Klopp and Anis Djari and Diane Esquerr{\'{e}} and Pascal GP Martin and Tatiana Zerjal and David Gourichon and Fr{\'{e}}d{\'{e}}rique Pitel and Sandrine Lagarrigue(2016). The Extent of mRNA Editing Is Limited in Chicken Liver and Adipose, but Impacted by Tissular Context, Genotype, Age, and Feeding as Exemplified with a Conserved Edited Site in COG3 . Genes|Genomes|Genetics. 6. (2). p. 321--335. Genetics Society of America
Frésard, L. and Leroux, S. and Roux, P.-F. and Klopp, C. and Fabre, S. and Esquerré, D. and Dehais, P. and Djari, A. and Gourichon, D. and Lagarrigue, S. and Pitel, F.(2015). Genome-wide characterization of RNA editing in chicken embryos reveals common features among vertebrates . PLoS ONE. 10. (5).
Roux, P.-F. and Boitard, S. and Blum, Y. and Parks, B. and Montagner, A. and Mouisel, E. and Djari, A. and Esquerré, D. and Désert, C. and Boutin, M. and Leroux, S. and Lecerf, F. and Bihan-Duval, E.L. and Klopp, C. and Servin, B. and Pitel, F. and Duclos, M.J. and Guillou, H. and Lusis, A.J. and Demeure, O. and Lagarrigue, S.(2015). Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation . Genes|Genomes|Genetics. 5. (4). p. 517-529.
Roux, P.F. and Marthey, S. and Djari, A. and Moroldo, M. and Esquerré, D. and Estellé, J. and Klopp, C. and Lagarrigue, S. and Demeure, O.(2015). Comparison of whole-genome (13X) and capture (87X) resequencing methods for SNP and genotype callings . Animal Genetics. 46. (1). p. 82-86.
Roux, P.-F. and Boutin, M. and Désert, C. and Djari, A. and Esquerré, D. and Klopp, C. and Lagarrigue, S. and Demeure, O.(2014). Re-sequencing data for refining candidate genes and polymorphisms in QTL regions affecting adiposity in chicken . PLoS ONE. 9. (10).
Lagarrigue, S. and Martin, L. and Hormozdiari, F. and Roux, P. and Pan, C. and van Nas, A. and Demeure, O. and Cantor, R. and Ghazalpour, A. and Eskin, E. and Lusis, A.J.(2013). Analysis of allele-specific expression in mouse liver by RNA-seq: A comparison with Cis-eQTL identified using genetic linkage . Genetics. 195. (3). p. 1157-1166.
Simonin-Le Jeune, K. and Le Jeune, A. and Jouneau, S. and Belleguic, C. and Roux, P.-F. and Jaguin, M. and Dimanche-Boitre, M.-T. and Lecureur, V. and Leclercq, C. and Desrues, B. and Brinchault, G. and Gangneux, J.-P. and Martin-Chouly, C.(2013). Impaired Functions of Macrophage from Cystic Fibrosis Patients: CD11b, TLR-5 Decrease and sCD14, Inflammatory Cytokines Increase . PLoS ONE. 8. (9).
OTHER
Martínez-Zamudio, R.I., Roux, P.-F., de Freitas, J.A.N.L.F., Robinson, L., Doré, G., Sun, B., Gil, J., Herbig, U., Bischof, O.(2019). AP-1 Imprints a Reversible Transcriptional Program of Senescent Cells . bioRxiv.
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