Profile Details

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USD 60 /hr

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Hire Dr. Paromita R.

Canada

USD 60 /hr

Scientist, Scientific Reviewer and Editor with 6+ years of experience in drug discovery.

Profile Summary

My passion to find solutions to complex scientific problems has led to over 15 years of research experience in various fields including structural biology, protein purification, translational oncology, preclinical drug discovery and food technology. I have always taken a multidisciplinary approach to tackle scientific problems, with a focus on disease intervention therapy. Using protein biochemistry and molecular biology tools I have contributed to drug discovery research in cancer therapy, pertaining to in vitro assay development in preclinical models. I have worked with different biological systems ranging from bacteria to mammalian cell lines, and mouse tumor models. Currently, I lead the food science research in a food technological startup geared to provide healthy food solutions to consumers in the comfort of their own kitchen. Alongside my day job I love to freelance as a Scientific Reviewer and Editor.

Subject Matter Expertise

• ★ Oncology
• ☆ Separation & Purification
• ☆ Biochemistry
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Food Science
• ☆ Protein/Enzyme Engineering
• ☆ Clinical Trials

Services

• Writing

Writing Clinical Trial Documentation, Technical Writing

Work Experience

Freelance Scientific Editor

Wordvice

July 2019 - Present

Senior Scientist

Lecker Labs Canada Inc

July 2018 - Present

Freelance Expert Scientific Reviewer

Edanz Group Ltd

June 2016 - Present

Scientist

SignalChem

September 2016 - July 2018

Education

Postdoc

University of California, San Francisco

August 2010 - August 2014

Ph.D

University of Calcutta

August 2003 - April 2010

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2016). A phase I trial of panobinostat and epirubicin in solid tumors with a dose expansion in patients with sarcoma . Annals of Oncology.

(2016). Conformational selection underpins recognition of multiple DNA sequences by proteins and consequent functional actions . Physical Chemistry Chemical Physics.

(2015). Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression . Breast Cancer Research.

(2013). Histone Deacetylase Regulation of ATM-Mediated DNA Damage Signaling . Molecular Cancer Therapeutics.

(2013). Efficacy of Histone Deacetylase and Estrogen Receptor Inhibition in Breast Cancer Cells Due to Concerted down Regulation of Akt . PLoS ONE.

(2011). High-Affinity Quasi-Specific Sites in the Genome: How the DNA-Binding Proteins Cope with Them . Biophysical Journal.

(2011). Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance . Epigenomics.

(2011). A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer . British Journal of Cancer.

(2010). Alternative Sigma Factors in the Free State Are Equilibrium Mixtures of Open and Compact Conformations . Biochemistry.

BOOK CHAPTER

(2016). Outcome of Combining Epigenetic Drugs with Other Treatments in the Clinic . Medical Epigenetics.