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Hire Morteza S.

United States

USD 95 /hr

Sr. Scientist with +10 YOE in Pharmaceutics, AI/ML, and Medical Devices, with +40 publications and an MIT PhD

Profile Summary

Experienced Sr. Research Scientist with 10 years of combined experience in industry and academia. Experienced in formulation and process development for small and large molecules, scientific writing, analytical testing, drug delivery systems, AI/ML application, DOE, advanced analytics, optimization methods, CFD/FEA simulation. Have published over 40 research papers and 1 US patent. PhD in Mechanical Engineering from MIT

Subject Matter Expertise

• ☆ Materials Science & Engineering
• ☆ Analytical Chemistry
• ☆ Thermal Analysis
• ☆ Nanotechnology
• ☆ Data Analysis
• ☆ Artificial Intelligence
• ☆ Renewable Energy
• ☆ STATA
• ☆ R
• ☆ Drug Development
• ☆ Drug Formulation
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Drug Substance Characterization
• ☆ Solid Form Screening
• ☆ Bioanalytical Testing
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Drug-Drug Interactions
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Pharmaceutical Regulatory Affairs
• ☆ Medical Devices
• ☆ Medical Device Development
• ☆ Biocompatibility Testing
• ☆ Medical Device Design
• ☆ Medical Implants
• ☆ Wearable Technology
• ☆ Medical Device Prototyping
• ☆ Pharmaceutical Management
• ☆ Pharmaceutical Technology
• ☆ Regulatory Writing
• ☆ Medical Device Regulatory Writing
• ☆ Medical Device Literature Reviews
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Business & Legal Writing, Copywriting, Creative Writing, Newswriting, Audio Transcription, General Proofreading & Editing, Translation

Research Market Research, User Research, Meta-Research, Feasibility Study, Technology Scouting, Fact Checking, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Business Strategy Consulting, Go-to-Market Strategy Consulting, Digital Strategy Consulting, Healthcare Consulting, Legal Consulting, Operations Consulting, Scientific and Technical Consulting, Financial Consulting, Regulatory Consulting, Manufacturing Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

Product Development Formulation, Recipe Development, Deformulation, Stability/Shelf Life Testing, Product Evaluation, Material Sourcing, Product Validation, Manufacturing, Quality Assurance & Control (QA/QC), Product Compliance , Concept Development, Product Launch Support, Packaging Design, Prototyping, Reverse Engineering, Device Fabrication

Work Experience

Gilead Sciences (United States)

- Present

Sr. Scientist

Gilead Sciences

August 2023 - Present

Scientist III

SiO2 Medical Products

March 2023 - September 2023

Research Scientists

Syntis Bio

October 2022 - March 2023

Scientist III

SiO2 Medical Products

October 2021 - March 2023

Research Specialist

Massachusetts Institute of Technology

October 2021 - October 2022

Education

PhD

Massachusetts Institute of Technology

September 2017 - October 2021

Certifications

• Healthcare

  MIT Sloan School of Management

  May 2021 - Present

• Business Analytics

  MIT Sloan School of Management

  May 2021 - Present

• Graduate Education in Medical Sciences

  Harvard-MIT Division of Health Sciences and Technology

  May 2021 - Present

Publications

JOURNAL ARTICLE

(2025). Improving Glioblastoma Prognosis with MRI-Based Machine Learning . Preprints.

(2024). A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS₂-Based Microparticles in a Breast Cancer Model . ACS NANO.

(2024). A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines . NATURE BIOTECHNOLOGY.

(2024). A quantitative analysis of Alzheimers Disease and construction of an early Alzheimers detection deep learning system (EADDLS) using MRI data via machine learning along with ADmod: spatiotemporal-aware brain-amyloidβ growth model, using deep encoder-decoder networks about MRI . medRxiv.

(2024). Brain tumor MRI classification and identification using an image classification model via Convolutional Neural Networks . medRxiv.

(2024). Comparative Analysis of Data Preprocessing Methods, Feature Selection Techniques and Machine Learning Models for Improved Classification and Regression Performance on Imbalanced Genetic Data. Arxiv.

(2024). On-Patient Temporary Medical Record for Accurate, Time-Sensitive Information at the Point of Care . ADVANCED FUNCTIONAL MATERIALS.

(2024). Predicting Loss-of-Function Impact of Genetic Mutations: A Machine Learning Approach. ADVANCES IN ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING.

(2024). Predicting loss-of-function impact of genetic mutations: a machine learning approach. Arxiv.

(2024). The Application of Convolutional Neural Networks in Organ-on-a-Chip Technology: A Review . Preprints.

(2024). Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer . SCIENCE ADVANCES.

(2023). A Machine Learning-optimized system for on demand, pulsatile, photo- and chemo-therapeutic treatment using near-infrared responsive MoS2-based microparticles in a breast cancer model . bioRxiv.

(2023). A comparative study of freeze-drying heat transfer in polymeric vials and glass vials . SCIENTIFIC REPORTS.

(2023). Photo-activatable ON-OFF microparticles for on-demand pulsatile drug delivery in a breast cancer model . CANCER RESEARCH.

(2023). Recent advances in nano- and micro-scale carrier systems for controlled delivery of vaccines . BIOMATERIALS.

(2022). Experimental and computational understanding of pulsatile release mechanism from biodegradable core-shell microparticles . SCIENCE ADVANCES.

(2022). Micromolding of Thermoplastic Polymers for Direct Fabrication of Discrete, Multilayered Microparticles . SMALL METHODS.

(2022). The road ahead for applications of mechanics in drug delivery br . MECHANICS RESEARCH COMMUNICATIONS.

(2021). Continuous Flow Synthesis of Persistent Luminescent Chromium-Doped Zinc Gallate Nanoparticles . JOURNAL OF PHYSICAL CHEMISTRY LETTERS.

(2020). Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy . SCIENCE TRANSLATIONAL MEDICINE.

(2020). Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations . SCIENCE ADVANCES.

(2019). Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination . SCIENCE TRANSLATIONAL MEDICINE.

(2018). Accelerated full-thickness wound healing via sustained bFGF delivery based on a PVA/chitosan/gelatin hydrogel incorporating PCL microspheres . INTERNATIONAL JOURNAL OF PHARMACEUTICS.

(2017). Investigation on the best process criteria for lap joint friction stir welding of AA1100 aluminium alloy via Taguchi technique and ANOVA (2016) . PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART E-JOURNAL OF PROCESS MECHANICAL ENGINEERING.

(2017). Investigation on the best process criteria for lap joint friction stir welding of AA1100 aluminum alloy via Taguchi technique and ANOVA . PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART E-JOURNAL OF PROCESS MECHANICAL ENGINEERING.

(2017). Reliability-based robust multi-objective optimization of a 5-DOF vehicle vibration model subjected to random road profiles . JOURNAL OF CENTRAL SOUTH UNIVERSITY.

(2017). Sensitivity analysis and optimization of hot-stamping process of automotive components using analysis of variance and Taguchi technique . PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART E-JOURNAL OF PROCESS MECHANICAL ENGINEERING.

(2017). Utilization of Molecular Dynamics Simulation Coupled with Experimental Assays to Optimize Biocompatibility of an Electrospun PCL/PVA Scaffold . PLOS ONE.

(2016). Investigation of the adhesive characteristics of polymer-protein systems through molecular dynamics simulation and their relation to cell adhesion and proliferation . Integrative Biology.

(2016). Probabilistic multi-objective optimization of a corrugated-core sandwich structure . GEOMECHANICS AND ENGINEERING.

(2015). Investigation on the optimal simplified model of BIW structure using FEM . LATIN AMERICAN JOURNAL OF SOLIDS AND STRUCTURES.