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★★★★★

☆☆☆☆☆

USD 200 /hr

★★★★★

☆☆☆☆☆

Hire Michael M.

United States

USD 200 /hr

Yale, Stanford, and NYU-trained scientist with 13+ years of experience in RNA/DNA chemistry and biology

Profile Summary

Test summary

Subject Matter Expertise

• ☆ Biocatalysis
• ☆ Molecular Engineering
• ☆ Biopolymers
• ☆ Analytical Chemistry
• ☆ Spectroscopy
• ☆ UV Spectroscopy
• ☆ Fluorescence Spectroscopy
• ☆ Liquid Chromatography/HPLC
• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Omics
• ☆ Transcriptomics
• ☆ Genomics
• ☆ Molecular Evolution
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Recombinant DNA
• ☆ RNA Synthesis
• ☆ RNA Sequencing
• ☆ DNA/Gene Synthesis
• ☆ Oligonucleotide Synthesis
• ☆ Plasmid DNA
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Gene Regulation
• ☆ Biotechnology & Bioengineering
• ☆ Nanobiotechnology
• ☆ Applied Chemistry
• ☆ Cell Culture
• ☆ Cell Line Engineering
• ☆ Synthetic Biology
• ☆ Biosensors
• ☆ Chemical Biology
• ☆ Biomolecular Engineering
• ☆ Genetic Engineering
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Medicinal Chemistry
• ☆ Drug Design
• ☆ Combinatorial Chemistry
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ In vitro Diagnostics
• ☆ In vitro Diagnostic Validation
• ☆ In vitro Diagnostic Design
• ☆ Point-of-Care Devices
• ☆ Gene Therapy

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing

Research Market Research, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Data Visualization, Data Mining, Data Processing

Work Experience

Postdoctoral Fellow

Yale University

July 2020 - Present

Education

PhD (Chemistry)

Stanford University

June 2015 - June 2020

BS (Chemistry)

New York University

September 2011 - May 2015

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Kumari Kavita, Aya Narunsky, Jessica J. Mohsen, Isha Mahadeshwar, Michael G. Mohsen, Yu-Shin Chang, Ronald R. Breaker (2025). Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function . Nature Communications.

Michael G. Mohsen, Matthew K. Midy, Aparaajita Balaji, Ronald R. Breaker (2024). Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches . ACS Chemical Biology.

Linglan Fang, Willem A. Velema, Yujeong Lee, Lu Xiao, Michael G. Mohsen, Anna M. Kietrys, Eric T. Kool (2023). Pervasive transcriptome interactions of protein-targeted drugs . Nature Chemistry.

Michael G Mohsen, Matthew K Midy, Aparaajita Balaji, Ronald R Breaker (2023). Exploiting natural riboswitches for aptamer engineering and validation . Nucleic Acids Research.

Mohsen, M.G., Breaker, R.R.(2023). In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers . Bio-protocol. 13. (13).

Mohsen, M.G., Midy, M.K., Balaji, A., Breaker, R.R.(2023). Exploiting natural riboswitches for aptamer engineering and validation . Nucleic Acids Research. 51. (2). p. 966-981.

Lee, Y., Onishi, Y., McPherson, L., Kietrys, A.M., Hebenbrock, M., Jun, Y.W., Das, I., Adimoolam, S., Ji, D., Mohsen, M.G., et al.(2022). Enhancing Repair of Oxidative DNA Damage with Small-Molecule Activators of MTH1 . ACS Chemical Biology. 17. (8). p. 2074-2087.

Ohayon, Y.P., Hernandez, C., Chandrasekaran, A.R., Wang, X., Abdallah, H.O., Jong, M.A., Mohsen, M.G., Sha, R., Birktoft, J.J., Lukeman, P.S., et al.(2019). Designing Higher Resolution Self-Assembled 3D DNA Crystals via Strand Terminus Modifications . ACS Nano. 13. (7). p. 7957-7965.

McPherson, L.A., Troccoli, C.I., Ji, D., Bowles, A.E., Gardiner, M.L., Mohsen, M.G., Nagathihalli, N.S., Nguyen, D.M., Robbins, D.J., Merchant, N.B., et al.(2019). Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue . DNA Repair. 83.

Mohsen, M.G., Ji, D., Kool, E.T.(2019). Polymerase synthesis of four-base DNA from two stable dimeric nucleotides . Nucleic Acids Research. 47. (18). p. 9495-9501.

Mohsen, M.G., Ji, D., Kool, E.T.(2019). Polymerase-amplified release of ATP (POLARA) for detecting single nucleotide variants in RNA and DNA . Chemical Science. 10. (11). p. 3264-3270.

Ji, D., Mohsen, M.G., Harcourt, E.M., Kool, E.T.(2016). ATP-releasing nucleotides: Linking DNA synthesis to luciferase signaling . Angewandte Chemie - International Edition. 55. (6). p. 2087-2091.

Mohsen, M.G., Kool, E.T.(2016). The Discovery of Rolling Circle Amplification and Rolling Circle Transcription . Accounts of Chemical Research. 49. (11). p. 2540-2550.

Oertell, K., Harcourt, E.M., Mohsen, M.G., Petruska, J., Kool, E.T., Goodman, M.F.(2016). Kinetic selection vs.free energy of DNA base pairing in control of polymerase fidelity . Proceedings of the National Academy of Sciences of the United States of America. 113. (16). p. E2277-E2285.

OTHER

Fang, L., Velema, W.A., Lee, Y., Lu, X., Mohsen, M.G., Kietrys, A.M., Kool, E.T.(2022). Pervasive Transcriptome Interactions of Protein-Targeted Drugs . bioRxiv.