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Profile Details
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Hire Dr. Michael J.
United States

Dr. James is a PhD scientist offering medical science and bioscience consulting, writing, editing and review services.

Profile Summary
Subject Matter Expertise
Writing Clinical Trial Documentation, Technical Writing, Newswriting
Research Market Research, Feasibility Study, Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection
Consulting Scientific and Technical Consulting
Data & AI Big Data Analytics
Product Development Product Evaluation, Product Validation, Concept Development
Work Experience

Scientific Consultant


January 2019 - Present

Scientific Peer Review and Talent Evaluation Consultant

Cactus Global

October 2015 - Present

Scientific Content Editor

Cactus Global

October 2015 - Present

President and Chief Scientific Officer

Essential Biotechnology LLC

January 2015 - Present

Senior Scientist

NanoRed Biotechnology LLC

January 2019 - January 2022


Medical College of Wisconsin

October 2014 - February 2019

Research Assistant Professor

Medical College of Wisconsin

July 2010 - October 2014

Postdoctoral Research Associate

Washington University School of Medicine, St. Louis

July 2006 - July 2010



University of Iowa, Carver College of Medicine

August 2000 - May 2006


Mercy School of Clinical Laboratory Science

July 1997 - June 1998

Bachelor of Science, Microbiology, Cum Laude

Iowa State University

August 1992 - December 1996

  • MT


    July 2000 - Present

  • CLS


    July 2000 - Present

Xiao, F., Zhang, P., Wang, Y., Tian, Y., James, M., Huang, C.-C., Wang, L., Wang, L.(2020). Single-nucleotide polymorphism rs13426236 contributes to an increased prostate cancer risk via regulating MLPH splicing variant 4 . Molecular Carcinogenesis. 59. (1). p. 45-55.
William R. Clarke, Laufey Amundadottir, Michael A. James(2019). {CLPTM}1L/{CRR}9 ectodomain interaction with {GRP}78 at the cell surface signals for survival and chemoresistance upon {ER} stress in pancreatic adenocarcinoma cells . International Journal of Cancer. 144. (6). p. 1367--1378. Wiley
Clarke, W.R., Amundadottir, L., James, M.A.(2019). CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells . International Journal of Cancer. 144. (6). p. 1367-1378.
Tsai, S., McOlash, L., Palen, K., Johnson, B., Duris, C., Yang, Q., Dwinell, M.B., Hunt, B., Evans, D.B., Gershan, J., et al.(2018). Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models . BMC Cancer. 18. (1).
Bodle, C.R., Mackie, D.I., Hayes, M.P., Schamp, J.H., Miller, M.R., Henry, M.D., Doorn, J.A., Houtman, J.C.D., James, M.A., Roman, D.L.(2017). Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines . Journal of Natural Products. 80. (7). p. 1992-2000.
Puskás, L.G., Mán, I., Szebeni, G., Tiszlavicz, L., Tsai, S., James, M.A.(2016). Novel Anti-CRR9/CLPTM1L antibodies with antitumorigenic activity inhibit cell surface accumulation, PI3K interaction, and survival signaling . Molecular Cancer Therapeutics. 15. (5). p. 985-997.
Lee, Y., Wang, Y., James, M., Jeong, J.H., You, M.(2016). Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells . Molecular Carcinogenesis. 55. (5). p. 991-1001.
Lieberman, R., Xiong, D., James, M., Han, Y., Amos, C.I., Wang, L., You, M.(2016). Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus . Molecular Carcinogenesis. 55. (5). p. 953-963.
James, M.A., Vikis, H.G., Tate, E., Rymaszewski, A.L., You, M.(2014). CRR9/CLPTM1L regulates cell survival signaling and is required for ras transformation and lung tumorigenesis . Cancer Research. 74. (4). p. 1116-1127.
James, M.A., Seibel, W.L., Kupert, E., Hu, X.X., Potharla, V.Y., Anderson, M.W.(2014). A novel, soluble compound, C25, sensitizes to TRAIL-induced apoptosis through upregulation of DR5 expression . Anti-Cancer Drugs. 26. (5). p. 518-530.
James, M.A., Wen, W., Wang, Y., Byers, L.A., Heymach, J.V., Coombes, K.R., Girard, L., Minna, J., You, M.(2012). Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus . PLoS ONE. 7. (6).
Lu, Y., Liu, P., Van Den Bergh, F., Zellmer, V., James, M., Wen, W., Grubbs, C.J., Lubet, R.A., You, M.(2012). Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer . Cancer Prevention Research. 5. (2). p. 248-259.
Liu, P., Morrison, C., Wang, L., Xiong, D., Vedell, P., Cui, P., Hua, X., Ding, F., Lu, Y., James, M., et al.(2012). Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing . Carcinogenesis. 33. (7). p. 1270-1276.
James, M.A., Fu, H., Liu, Y., Chen, D., You, M.(2011). Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis . Molecular Carcinogenesis. 50. (1). p. 1-7.
Freedman, M.L., Monteiro, A.N.A., Gayther, S.A., Coetzee, G.A., Risch, A., Plass, C., Casey, G., De Biasi, M., Carlson, C., Duggan, D., et al.(2011). Principles for the post-GWAS functional characterization of cancer risk loci . Nature Genetics. 43. (6). p. 513-518.
Wang, Y., James, M., Wen, W., Lu, Y., Szabo, E., Lubet, R.A., You, M.(2010). Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice . Molecular Cancer Therapeutics. 9. (11). p. 3074-3082.
Yan, L., Pengyuan, L., Weidong, W., James, M.A., Yian, W., Bailey-Wilson, J.E., Amos, C.I., Pinney, S.M., Ping, Y., De Andrade, M., et al.(2009). Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1 . Cancer Research. 69. (19). p. 7844-7850.
You, M., Wang, D., Liu, P., Vikis, H., James, M., Lu, Y., Wang, Y., Wang, M., Chen, Q., Jia, D., et al.(2009). Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene . Clinical Cancer Research. 15. (8). p. 2666-2674.
Lu, Y., Yi, Y., Liu, P., Wen, W., James, M., Wang, D., You, M.(2007). Common human cancer genes discovered by integrated gene-expression analysis . PLoS ONE. 2. (11).
Vikis, H., Sato, M., James, M., Wang, D., Wang, Y., Wang, M., Jia, D., Liu, Y., Bailey-Wilson, J.E., Amos, C.I., et al.(2007). EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity . Cancer Research. 67. (10). p. 4665-4670.
Boyle, K.A., James, M.A., Tsai, S., Evans, D.B., Dwinell, M.B.(2018). Stromal inflammation in pancreatic cancer: Mechanisms and translational applications . Pancreatic Cancer. p. 481-508.