Profile Details

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USD 77 /hr

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Hire Dr. Marilyne L.

France

USD 77 /hr

Preclinical Strategist and Analyst, Molecular & Cell Biologist, Scientific Communication, Design Thinking

Profile Summary

I aim to create positive, enduring change in Healthcare and Life Sciences with a diverse- and gender-sensitive focus. Using a quantitative and qualitative analytical approach, by combining scientific rationality, ethics of care and design thinking, I aim to support global projects and inspire compelling strategies to add layers of care guidance into your business, innovation & health decisions. As an NGO board member and volunteer, I also advocate for diversity, equity, inclusion and belonging in the healthcare business and science at large. I have supported Go/No-Go decisions in biomedical discovery and preclinical studies while creating content and sharing insights for more than 10+ years with four research institutes, NGOs, a hospital, biotech, a European consortium & industry partners. I advanced projects related to infectious diseases, oncology, four neurological indications, focussing as following on: * Disease and physiology understanding * Signalling pathways and molecular interactions * Assays implementation and validation * Conventional & innovative therapeutic preclinical development * Drug mechanisms of action Excellent track record through scientific publications and communications, partnerships, funding proposals, coaching, root cause investigation & process optimization for a broad range of in-vitro and in-vivo assessments.

Subject Matter Expertise

• ★ Design Thinking
• ★ Preclinical Research
• ★ Science Communication
• ☆ Molecular Imaging
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Molecular Biology
• ☆ Cell Signaling Pathways
• ☆ Neuropharmacology
• ☆ Neurobiology
• ☆ Cell Culture
• ☆ Protein/Enzyme Engineering
• ☆ Antibody Engineering
• ☆ Inclusive Education
• ☆ Epilepsy & Seizures
• ☆ Depression
• ☆ Immunotherapy
• ☆ Gene Therapy
• ☆ Medical Sciences
• ☆ Project Management

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Algorithm Design-Non ML, Data Visualization, Data Processing, Data Insights

Product Development Product Validation, Concept Development

Work Experience

Director, Member Engagement and Board member

The Healthcare Businesswomen's Association

December 2019 - Present

Board Member and Director, member engagement

The Healthcare Businesswomen's Association (HBA)

December 2019 - Present

Independent Scientist & Consultant

Self-employed

April 2017 - Present

Molecular and Cellular Project Manager

Theranyx

January 2016 - December 2016

Senior Research Fellow- Marie Sklodowska-Curie Research Fellowship

European consortium Epixchange | University of Ferrara

June 2013 - May 2015

Senior Project Manager

THE CENTER FOR RESEARCH IN NEUROBIOLOGY AND NEUROPHYSIOLOGY OF MARSEILLE (CRN2M)

November 2008 - September 2012

Project Manager

THE FUNCTIONAL GENOMIC INSTITUTE (IGF)

October 2004 - October 2008

Research Assistant

INSTITUT COCHIN

October 2000 - June 2004

Education

PhD | Neuroscience

University of Montpellier

October 2004 - October 2008

MSc in Biochemistry and Molecular Biology, with a specialty in Immunology and Virology, with the highest honours

Université Paris Diderot

September 2002 - June 2004

Certifications

• Introduction to the Black Swan Method - Negotiation 9

  The Black Swan Group

  June 2021 - Present

• Certification in Philosophy, Ethics of Care and Design

  CNAM, Paris

  October 2020 - Present

• Prince2 Project Management certifications

  Axelos Global Best Practice

  November 2018 - Present

• Cambridge Advance Certificate

  Cambridge Assessment English

  June 2017 - Present

• Design and Interpretation of Clinical Trials

  coursera

  November 2016 - Present

• Guideline for ICH - Good Clinical Practice (E6(R1))

  Medical Trial Analysis

  November 2016 - Present

• Certificate of Knowledge of Italian as Foreign Language

  University of Siena for Foreigners

  June 2014 - Present

• Technical Certificate in Biomedical Research, specialty in Virology

  ESTBA, Paris

  June 2001 - Present

Publications

JOURNAL ARTICLE

Francesca Lovisari and Paolo Roncon and Marie Soukoupova and Giovanna Paolone and Marilyne Labasque and Selene Ingusci and Chiara Falcicchia and Pietro Marino and Michael Johnson and Tiziana Rossetti and Enrico Petretto and Karine Leclercq and Rafal M Kaminski and Ben Moyon and Zoe Webster and Michele Simonato and Silvia Zucchini(2021). Implication of sestrin3 in epilepsy and its comorbidities . Brain Communications. 3. (1). Oxford University Press ({OUP})

Hivert, B., Pinatel, D., Labasque, M., Tricaud, N., Goutebroze, L., Faivre-Sarrailh, C.(2016). Assembly of juxtaparanodes in myelinating DRG culture: Differential clustering of the Kv1/Caspr2 complex and scaffolding protein 4.1B . GLIA. 64. (5). p. 840-852.

Labasque M, Hivert B, Nogales-Gadea G, Querol L, Illa I, Faivre-Sarrailh C, The Journal of biological chemistry, 2014, vol. 289, no. 11, pp. 7907-7918 .

Labasque, M., Hivert, B., Nogales-Gadea, G., Querol, L., Illa, I., Faivre-Sarrailh, C.(2014). Specific contactin N-glycans are implicated in neurofascin binding and autoimmune targeting in peripheral neuropathies . Journal of Biological Chemistry. 289. (11). p. 7907-7918.

Papouin T, Ladépêche L, Ruel J, Sacchi S, Labasque M, Hanini M, Groc L, Pollegioni L, Mothet JP, Oliet SH, Cell, 2012, vol. 150, no. 3, pp. 633-646 .

Papouin, T., Ladépêche, L., Ruel, J., Sacchi, S., Labasque, M., Hanini, M., Groc, L., Pollegioni, L., Mothet, J.-P., Oliet, S.H.R.(2012). Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists . Cell. 150. (3). p. 633-646.

Labasque M, Devaux JJ, Lévêque C, Faivre-Sarrailh C, The Journal of biological chemistry, 2011, vol. 286, no. 49, pp. 42426-42434 .

Millan MJ, Marin P, Kamal M, Jockers R, Chanrion B, Labasque M, Bockaert J, Mannoury la Cour C, The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 2011, vol. 14, no. 6, pp. 768-783 .

Labasque, M., Devaux, J.J., Lévêque, C., Faivre-Sarrailh, C.(2011). Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of ranvier . Journal of Biological Chemistry. 286. (49). p. 42426-42434.

Millan, M.J., Marin, P., Kamal, M., Jockers, R., Chanrion, B., Labasque, M., Bockaert, J., La Cour, C.M.(2011). The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT<inf>2C</inf>receptors . International Journal of Neuropsychopharmacology. 14. (6). p. 768-783.

Labasque M, Meffre J, Carrat G, Becamel C, Bockaert J, Marin P, Molecular pharmacology, 2010, vol. 78, no. 5, pp. 818-826 .

Labasque M, Faivre-Sarrailh C, FEBS letters, 2010, vol. 584, no. 9, pp. 1787-1792 .

Thaxton C, Pillai AM, Pribisko AL, Labasque M, Dupree JL, Faivre-Sarrailh C, Bhat MA, The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, vol. 30, no. 14, pp. 4868-4876 .

Thaxton, C., Pillai, A.M., Pribisko, A.L., Labasque, M., Dupree, J.L., Faivre-Sarrailh, C., Bhat, M.A.(2010). In vivo deletion of immunoglobulin domains 5 and 6 in Neurofascin (Nfasc) reveals domain-specific requirements in myelinated axons . Journal of Neuroscience. 30. (14). p. 4868-4876.

Labasque, M., Faivre-Sarrailh, C.(2010). GPI-anchored proteins at the node of Ranvier . FEBS Letters. 584. (9). p. 1787-1792.

Labasque, M., Meffre, J., Carrat, G., Becamel, C., Bockaert, J., Marin, P.(2010). Constitutive activity of serotonin<inf>2C</inf>receptors at G protein-independent signaling: Modulation by RNA editing and antidepressants . Molecular Pharmacology. 78. (5). p. 818-826.

Labasque M, Reiter E, Becamel C, Bockaert J, Marin P, Molecular biology of the cell, 2008, vol. 19, no. 11, pp. 4640-4650 .

Couty JP, Crain AM, Gerbaud S, Labasque M, Marchiol C, Fradelizi D, Boudaly S, Guettier C, Vignuzzi M, van der Werf S, Escriou N, Viguier M, Cancer immunology, immunotherapy : CII, 2008, vol. 57, no. 8, pp. 1161-1171 .

Couty, J.-P., Crain, A.-M., Gerbaud, S., Labasque, M., Marchiol, C., Fradelizi, D., Boudaly, S., Guettier, C., Vignuzzi, M., Van Der Werf, S., et al.(2008). Delivery of mengovirus-derived RNA replicons into tumoural liver enhances the anti-tumour efficacy of a peripheral peptide-based vaccine . Cancer Immunology, Immunotherapy. 57. (8). p. 1161-1171.

Labasque, M., Reiter, E., Becamel, C., Bockaert, J., Marin, P.(2008). Physical interaction of calmodulin with the 5-hydroxytryptamine<inf>2C</inf>receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling . Molecular Biology of the Cell. 19. (11). p. 4640-4650.