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Hire Dr. Mariana A.

Spain

USD 100 /hr

Medical Doctor | PhD Candidate in Molecular Biosciences | Genomic Research, Epidemiology, Oncology, and Bioinformatics.

Profile Summary

As a highly accomplished Medical Doctor and PhD Candidate in Molecular Biosciences, I offer a unique blend of clinical insight, advanced scientific research expertise, and robust analytical skills to the freelance market. My extensive academic background, including Master's degrees in Epidemiology and Bioinformatics, provides a multidisciplinary perspective essential for tackling complex challenges in health and life sciences, particularly through advanced multiomics analysis. With approximately 6 years of dedicated research experience at CIGGUR and CNIO, my professional focus lies in cutting-edge areas such as Molecular Oncology, genetics, genomic and transcriptomic analysis, and translational medicine, evidenced by a portfolio of high-impact publications. I possess deep subject matter expertise in Bioinformatics, Biostatistics, Data Science (including Machine Learning, Predictive Modeling, and various data analysis techniques), Molecular & Cell Biology (including Multiomics, NGS, RNA-Seq, scRNA-Seq), and Medical & Clinical Sciences (including Cancer Research, Clinical Trials, and comprehensive Epidemiology skills like Study Design and Scientific Protocol Development). Proficient in laboratory techniques and programming languages like Python and R, I combine strong technical capabilities with refined pedagogical and communication skills from four years as an academic tutor. I am a disciplined, committed, and responsible professional, driven by a passion for problem-solving and a proven track record of leadership, teamwork, and academic excellence, ready to deliver high-quality, impactful results.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Omics
• ☆ Transcriptomics
• ☆ Genomics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Damage & Repair
• ☆ Cell Biology
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Data Analysis
• ☆ Predictive Modeling & Analytics
• ☆ Data Processing
• ☆ Data Exploration
• ☆ Data Visualization
• ☆ Data Collection
• ☆ Data Management
• ☆ Data Manipulation
• ☆ Machine Learning
• ☆ Data Cleaning
• ☆ Neural Networks
• ☆ Bioinformatics
• ☆ Cell Culture
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Python
• ☆ Tensorflow
• ☆ R
• ☆ Scikit-learn
• ☆ Clinical Trials
• ☆ Clinical Data Management
• ☆ Clinical Trials Data Analysis
• ☆ Medical Genetics
• ☆ Immunogenetics
• ☆ Human Biology
• ☆ Precision Medicine
• ☆ Gastroenterology & Hepatology
• ☆ Colorectal Cancer
• ☆ Medical Education
• ☆ Continuing Medical Education (CME)
• ☆ Public Health
• ☆ Epidemiology
• ☆ Health Informatics
• ☆ Inflammation
• ☆ Cancer Research
• ☆ Cancer Biology

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Medical Writing, Technical Writing, Creative Writing

Research User Research, Feasibility Study, Gray Literature Search

Consulting Healthcare Consulting

Data & AI Predictive Modeling, Statistical Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization

Work Experience

PhD student

Centro Nacional de Investigaciones Oncológicas

October 2022 - Present

Research assistan

Colegio Mayor de Nuestra Señora del Rosario

August 2021 - August 2022

Education

Master's degree in bioinformatics and data science in personalized precision medicine and health

Escuela Nacional de Sanidad

October 2024 - March 2025

MSc in Epidemiology (School of Medicine and Health Sciences)

Universidad del Rosario

January 2021 - August 2023

Molecular biology and cytogenetics international master's degree (Molecular biology and cytogenetics )

Escuela ELBS

March 2021 - July 2021

Medical Doctor (School of Medicine and Health Sciences)

Universidad del Rosario

June 2015 - June 2021

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

María del Mar Rigual, Mariana Angulo-Aguado, Sladjana Zagorac, Ruth Álvarez-Díaz, Marta Benítez-Mondéjar, Fengming Yi, Carlos Martínez-Garay, Karla Santos-de-Frutos, Eunjeong Kim, Ramón Campos-Olivas, et al. (2025). Macrophages harness hepatocyte glutamate to boost liver regeneration . Nature.

Juliana Rodriguez-Salamanca, Mariana Angulo-Aguado, Sarah Orjuela-Amarillo, Catalina Duque, Diana Carolina Sierra-Díaz, Nora Contreras Bravo, Carlos Figueroa, Carlos M. Restrepo, Andrés López-Cortés, Rodrigo Cabrera, et al. (2025). Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer . Frontiers in Oncology.

Irene Herranz-Montoya, Mariana Angulo-Aguado, Cristian Perna, Sladjana Zagorac, Luis García-Jimeno, Solip Park, Nabil Djouder (2025). p53 protein degradation redefines the initiation mechanisms and drives transitional mutations in colorectal cancer . Nature Communications.

Omar Echeverría, Mariana Angulo-Aguado, Ricardo Vela, Carlos Calderón-Ospina, Katherine Parra, Nora Contreras, Adrien Morel, Rodrigo Cabrera, Carlos Restrepo, Carolina Ramírez-Santana, et al. (2024). The polygenic implication of clopidogrel responsiveness: Insights from platelet reactivity analysis and next-generation sequencing . PLOS ONE.

Rosa Gallo, Ana Teijeiro, Mariana Angulo-Aguado, Nabil Djouder (2024). IL-17A produced by POMC neurons regulates diet-induced obesity . iScience.

Diana Sierra-Díaz, Rodrigo Cabrera, Laura Gonzalez-Vasquez, Mariana Angulo-Aguado, Kevin Llinás-Caballero, Dora Fonseca-Mendoza, Nora Constanza Contreras-Bravo, Carlos Restrepo, Oscar Ortega-Recalde, Adrien Morel (2024). Functional Analysis of BRCA1 3’UTR Variants Predisposing to Breast Cancer . The Application of Clinical Genetics.

Mariana Angulo-Aguado, Juan Camilo Carrillo-Martinez, Nora Constanza Contreras-Bravo, Adrien Morel, Katherine Parra-Abaunza, William Usaquén, Dora Janeth Fonseca-Mendoza, Oscar Ortega-Recalde (2024). Next-generation sequencing of host genetics risk factors associated with COVID-19 severity and long-COVID in Colombian population . Scientific Reports.

Mariana Angulo-Aguado, Sarah Orjuela-Amarillo, Julián Francisco Mora-Jácome, Lea Paloma Córdoba, Antonio Gallego-Ortiz, Cristian Camilo Gaviria-Sabogal, Nora Contreras, Carlos Figueroa, Oscar Ortega-Recalde, Adrien Morel, et al.(2023). Functional analysis of CTLA4 promoter variant and its possible implication in colorectal cancer immunotherapy . Frontiers in Medicine. 10. Frontiers Media {SA}

William Armando Mantilla Durán, Diana Carolina Sierra Díaz, Adrien Morel, Nora Contreras, Mariana Angulo Aguado, Valentina Balaguera, Kevin Llinás Caballero, Isabel Munévar, Mariana Borras Osorio, Mauricio Lema, et al. (2023). Frecuencia de alteraciones germinales en genes de riesgo alto/moderado para riesgo de cáncer de mama hereditario : estudio multicéntrico en población no seleccionada . Revista Colombiana de Hematología y Oncología.

Juan Fernando Parada-Márquez, Nicolás David Maldonado-Rodriguez, Paula Triana-Fonseca, Nora Constanza Contreras-Bravo, Carlos Alberto Calderón-Ospina, Carlos M. Restrepo, Adrien Morel, Oscar Javier Ortega-Recalde, Daniel Felipe Silgado-Guzmán, Mariana Angulo-Aguado, et al.(2023). Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations . Frontiers in Pharmacology. 14. Frontiers Media {SA}

Daniel Felipe Silgado-Guzmán, Mariana Angulo-Aguado, Adrien Morel, María José Niño-Orrego, Daniel-Armando Ruiz-Torres, Nora Constanza Contreras Bravo, Carlos Martin Restrepo, Oscar Ortega-Recalde, Dora Janeth Fonseca-Mendoza(2022). Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing . Frontiers in Pharmacology. 13. Frontiers Media {SA}

Mariana Angulo-Aguado, David Corredor-Orlandelli, Juan Camilo Carrillo-Martínez, Mónica Gonzalez-Cornejo, Eliana Pineda-Mateus, Carolina Rojas, Paula Triana-Fonseca, Nora Constanza Contreras Bravo, Adrien Morel, Katherine Parra Abaunza, et al.(2022). Association Between the LZTFL1 rs11385942 Polymorphism and COVID-19 Severity in Colombian Population . Frontiers in Medicine. 9. Frontiers Media {SA}

Mariana Angulo-Aguado, Karen Panche, Caroll Andrea Tamayo-Agudelo, Daniel-Armando Ruiz-Torres, Santiago Sambracos-Parrado, Maria Jose Niño-Orrego, Nathaly Páez, Laura B Piñeros-Hernandez, Luisa-Fernanda Castillo-León, Juan Mauricio Pardo-Oviedo, et al.(2021). A Pharmacogenetic Study of CYP2C19 in Acute Coronary Syndrome Patients of Colombian Origin Reveals New Polymorphisms Potentially Related to Clopidogrel Therapy . Journal of Personalized Medicine. 11. (5). p. 400. {MDPI} {AG}

Mariana Angulo-Aguado, Karen Panche, Caroll Andrea Tamayo-Agudelo, Daniel-Armando Ruiz-Torres, Santiago Sambracos-Parrado, Maria Jose Ni&#241;o-Orrego, Nathaly P&#225;ez, Laura B Pi&#241;eros-Hernandez, Luisa-Fernanda Castillo-Le&#243;n, Juan Mauricio Pardo-Oviedo, et al. (2021). A Pharmacogenetic Study of <i>CYP2C19</i> in Acute Coronary Syndrome Patients of Colombian Origin Reveals New Polymorphisms Potentially Related to Clopidogrel Therapy . Journal of Personalized Medicine.