Profile Details

Contact

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Hire Dr. ManTek Y.

Canada

Profile Summary

My expertise in molecular genetics, genomics, and oncology will allow me to provide valuable support and insight to emerging strategies in personalized medicine, targeted molecular therapy, and immunotherapies for cancer and complex genetic diseases. I earned my PhD at the University of Toronto studying cell signaling pathways and how they are abnormal in cancer cells. I have used my experience since to devise translational preclinical studies to advance and influence scientific and medical strategies to treat blood malignancies and also prostate cancer. I am committed to effective scientific exchange to ensure that people from all educational backgrounds can understand sophisticated biological concepts which enables informed decision making in science-driven enterprises such as the pharmaceutical industry.

Subject Matter Expertise

• ☆ Biology/Life Sciences
• ☆ Microbiology
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Cell Signaling Pathways
• ☆ Stem Cell Research
• ☆ Phylogenetics
• ☆ Clinical Trials
• ☆ Oncology
• ☆ Hematology
• ☆ Leukemia & Lymphoma
• ☆ Immunotherapy
• ☆ Cancer Research
• ☆ Technical & Scientific Writing

Services

• Writing
• Consulting
• Data & AI
• Product Development

Work Experience

Senior Postdoctoral Fellow

Princess Margaret Hospital Cancer Centre

2014 - Present

Senior Postdoctoral Fellow

Princess Margaret Cancer Centre

September 2014 - March 2015

Research Associate

Ontario Institute for Cancer Research

November 2013 - April 2014

Research Associate

Ontario Institute for Cancer Research

2013 - 2014

Postdoctoral Fellow

Princess Margaret Cancer Centre, Ontario Cancer Institute

October 2011 - November 2013

Postdoctoral Fellow

Princess Margaret Hospital Cancer Centre

2011 - 2013

Doctoral Candidate

Lunenfeld-Tanenbaum Research Institute

September 2004 - June 2012

Doctoral Candidate

Lunenfeld-Tanenbaum Research Institute

2004 - 2012

NSERC Undergraduate Research Student

National Centre for Excellence, University of British Columbia

September 2002 - August 2004

Education

PhD

University of Toronto

September 2004 - June 2012

PhD (Molecular Genetics, Faculty of Medicine)

University of Toronto

September 2004 - June 2012

BSc

University of British Columbia

September 2000 - June 2004

BSc (Genetics, Biology)

University of British Columbia

2000 - 2004

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2015). Mitochondrial DNA damage by bleomycin induces AML cell death (in press). Apoptosis.

(2011). Srs2 enables checkpoint recovery by promoting disassembly of DNA damage foci from chromatin. DNA repair.

(2010). Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat Struct Mol Biol.

(2008). Engineering a DNA damage response without DNA damage. Genome Biol.

(2008). Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell.

(2006). Condensin is required for chromosome arm cohesion during mitosis. Genes and Development.