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Hire Dr. Kevin W.

South Africa

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Profile Summary

I am a synthetic organic chemist with experience in drug design and synthesis, medicinal chemistry, medicinal plants, green chemistry, biocatalysis and bioinorganic chemistry. I have published my research in international journals in the above research areas. My publications can be viewed at: - www.researchgate.net/profile/Kevin_Wellington I also have valuable experience in management reporting, information flow and management, business processes and organizational planning. I am particularly interested in projects related to: - academic writing - scientific writing - medical writing - consulting on scientific research - proofreading and editing

Subject Matter Expertise

• ☆ Catalysis
• ☆ Inorganic Chemistry
• ☆ Green Chemistry
• ☆ Organic Chemistry
• ☆ Protein/Enzyme Engineering
• ☆ Medicinal Chemistry
• ☆ Cancer Research
• ☆ Research
• ☆ Technical & Scientific Writing
• ☆ Proofreading & Editing

Services

• Writing
• Research
• Consulting
• Product Development

Work Experience

Consultant & Science writer

Freelancer

July 2018 - Present

Senior Scientist

Council for Scientific and Industrial Research

January 2007 - March 2018

Education

PhD Chemistry (Chemistry)

Rhodes University

1995 - 1999

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2020). InCl3: A Versatile Catalyst for Synthesizing a Broad Spectrum of Heterocycles . ACS Omega.

(2020). Incl<inf>3</inf>: A versatile catalyst for synthesizing a broad spectrum of heterocycles . ACS Omega.

(2020). Anticancer activity, apoptosis and a structure–activity analysis of a series of 1,4-naphthoquinone-2,3-bis-sulfides . Investigational New Drugs. 38. (2). p. 274-286.

Wellington, K.W., Hlatshwayo, V., Kolesnikova, N.I., Saha, S.T., Kaur, M., Motadi, L.R.(2020). Anticancer activities of vitamin K3 analogues . Investigational New Drugs. 38. (2). p. 378-391.

(2019). Acaricidal activity of the aqueous and hydroethanolic extracts of 15 South African plants against Rhipicephalus turanicus and their toxicity on human liver and kidney cells . Onderstepoort Journal of Veterinary Research.

Wellington, K.W., Nyoka, N.B.P., McGaw, L.J.(2019). Investigation of the antibacterial and antifungal activity of thiolated naphthoquinones . Drug Development Research. 80. (3). p. 386-394.

(2019). Investigation of the antimicrobial and anticancer activity of aminonaphthoquinones . Drug Development Research. 80. (1). p. 138-146.

(2019). Acaricidal activity of the aqueous and hydroethanolic extracts of 15 South African plants against rhipicephalus turanicus and their toxicity on human liver and kidney cells . Onderstepoort Journal of Veterinary Research. 86. (1).

(2018). A laccase-catalysed synthesis of triaminated cyclohexa-2,4-dienones from catechol . Journal of Catalysis. 368. p. 306-314.

(2017). Evaluation Of South African Plants With Acaricide Activity Against Ticks . Zenodo.

(2017). A one-pot laccase-catalysed synthesis of coumestan derivatives and their anticancer activity . Bioorganic and Medicinal Chemistry. 25. (3). p. 1172-1182.

(2017). Investigation of the acaricidal activity of the acetone and ethanol extracts of 12 South African plants against the adult ticks of Rhipicephalus turanicus . Onderstepoort Journal of Veterinary Research. 84. (1).

(2017). Further studies on South African plants: Acaricidal activity of organic plant extracts against Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) . Veterinary Parasitology. 234. p. 10-12.

(2016). Anthelmintic activity of acetone extracts from South African plants used on egg hatching of haemonchus contortus . Onderstepoort Journal of Veterinary Research. 83. (1).

(2016). Acaricidal activity of the organic extracts of thirteen South African plants against Rhipicephalus (Boophilus) decoloratus (Acari: Ixodidae) . Veterinary Parasitology. 224. p. 39-43.

Wellington, K.W.(2015). Understanding cancer and the anticancer activities of naphthoquinones-a review . RSC Advances. 5. (26). p. 20309-20338.

Wellington, K.W., Qwebani-Ogunleye, T., Wellington, K.W., Qwebani-Ogunleye, T., Kolesnikova, N.I., Brady, D., De Koning, C.B.(2013). One-pot laccase-catalysed synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives, and their anticancer activity . Archiv der Pharmazie. 346. (4). p. 266-277.

Wellington, K.W., Gordon, G.E.R., Ndlovu, L.A., Steenkamp, P.(2013). Laccase-Catalyzed C-S and C-C Coupling for a One-Pot Synthesis of 1,4-Naphthoquinone Sulfides and 1,4-Naphthoquinone Sulfide Dimers . ChemCatChem. 5. (6). p. 1570-1577.

Wellington, K.W., Bokako, R., Raseroka, N., Wellington, K.W., Bokako, R., Raseroka, N., Steenkamp, P.(2012). A one-pot synthesis of 1,4-naphthoquinone-2,3-bis-sulfides catalysed by a commercial laccase . Green Chemistry. 14. (9). p. 2567-2576.

(2010). Designer ligands. part 15. synthesis and characterisation of novel Mn(lI), Ni(II) and Zn(II) complexes of 1,10-phenanthroline-derived ligands . Arkivoc.

(2010). Diamination by N-coupling using a commercial laccase . Bioorganic and Medicinal Chemistry. 18. (4). p. 1406-1414.

(2009). A convenient synthesis of N,N'-dibenzyl-2,4-diaminopyrimidine-2'- deoxyribonucleoside and 1-Methyl-2'-deoxypseudoisocytidine . Nucleosides, Nucleotides and Nucleic Acids. 28. (4). p. 275-291.

(2008). Designer ligands. Part 14. Novel Mn(lI), Ni(II) and Zn(II) complexes of benzamide-and biphenyl-derived ligands . Arkivoc. 2008. (17). p. 248-264.

Wellington, K.W., Benner, S.A., Wellington, K.W., Benner, S.A.(2006). A review: Synthesis of aryl C-glycosides via the Heck coupling reaction . Nucleosides, Nucleotides and Nucleic Acids. 25. (12). p. 1309-1333.

(2005). Designer ligands. Part 13. Synthesis and catalytic activity of transition metal complexes of a macrocyclic ligand . South African Journal of Chemistry. 58. p. 1-3.

Dauvergne, J., Dauvergne, J., Wellington, K., Chibale, K.(2004). Unprecedented observation of sulfonamides in the transesterification of N-unsubstituted carbamates with sulfonyl chlorides . Tetrahedron Letters. 45. (1). p. 43-47.

Kaye, P.T., Nyokong, T., Watkins, G.M., Wellington, K.W.(2002). Designer ligands. Part 9. Catalytic activity of biomimetic cobalt(II) andcopper(II) complexes of multidentate ligands . Arkivoc. 2002. (9). p. 9-18.

(2001). Designer ligands. VII. Synthesis of biomimetic Schiff-base ligands . Synthetic Communications. 31. (16). p. 2405-2411.

Kaye, P.T., Wellington, K.W., Kaye, P.T., Wellington, K.W.(2001). Designer ligands. VI. Synthesis of 1,10-phenanthroline-based polydentate ligands . Synthetic Communications. 31. (6). p. 799-804.

(2000). Designer ligands. Part 5. Synthesis of polydentate biphenyl ligands . Synthetic Communications. 30. (3). p. 511-522.

BOOK

(2012). Application of laccases in organic synthesis: A review . Green Chemistry. p. 167-212.