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Hire Dr. James H.

United Kingdom

USD 100 /hr

Scientist with extensive expertise in molecular biology, epigenetics and next generation sequencing

Profile Summary

I have extensive expertise in molecular biology and next generation sequencing (NGS), and am available for consulting on NGS based projects/technologies such as RNA-seq, ChIP-seq and DNA-based sequencing.

Subject Matter Expertise

• ★ Transcriptomics
• ★ Epigenetics
• ★ Cancer Research
• ☆ Gene Editing/CRISPR
• ☆ Phylogenetics
• ☆ Audio Transcription

Services

• Services details not provided.

Work Experience

Postdoctoral research associate

Barts Cancer Institute

December 2015 - Present

Biologist

Chroma Therapeutics Ltd

September 2009 - June 2011

Education

PhD (Pharmacy and Pharmacology)

University of Bath

July 2011 - July 2014

Molecular Medicine Bsc hons

University of Sussex

September 2006 - June 2009

Certifications

• Certification details not provided.

Publications

OTHER

James A Heward, Lola Konali, Annalisa D’Avola, Karina Close, Alison Yeomans, Martin Philpott, James Dunford, Tahrima Rahim, Ahad F Al Seraihi, Jun Wang, et al.(2020). {KDM}5 inhibition offers a novel therapeutic strategy for the treatment of {KMT}2D mutant lymphomas . Cold Spring Harbor Laboratory

JOURNAL ARTICLE

Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J, Clear A, Iqbal S, et al.(2019). Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma . Leukemia.

Heward JA, Kumar EA, Korfi K, Okosun J, Fitzgibbon J(2018). Precision medicine and lymphoma . Current opinion in hematology.

Al Seraihi AF, Rio-Machin A, Tawana K, Bödör C, Wang J, Nagano A, Heward JA, Iqbal S, Best S, Lea N, et al.(2018). GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML . Leukemia.

Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J, Clear A, Iqbal S, et al.(2018). Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma . Leukemia.

Hamann PD, Roux BT, Heward JA, Love S, McHugh NJ, Jones SW, Lindsay MA(2017). Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis . Scientific reports.

Roux BT, Heward JA, Donnelly LE, Jones SW, Lindsay MA(2017). Catalog of Differentially Expressed Long Non-Coding RNA following Activation of Human and Mouse Innate Immune Response . Frontiers in Immunology.

Roux BT, Lindsay MA, Heward JA(2017). Knockdown of Nuclear-Located Enhancer RNAs and Long ncRNAs Using Locked Nucleic Acid GapmeRs . Methods in molecular biology (Clifton, N.J.).

Korfi K, Ali S, Heward JA, Fitzgibbon J(2017). Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations . Epigenetics.

Dawkins JB, Wang J, Maniati E, Heward JA, Koniali L, Kocher HM, Martin SA, Chelala C, Balkwill FR, Fitzgibbon J, et al.(2016). Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma . Cancer research.

Pearson MJ, Philp AM, Heward JA, Roux BT, Walsh DA, Davis ET, Lindsay MA, Jones SW(2016). Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis Cartilage . Arthritis & rheumatology (Hoboken, N.J.).

Araf S, Okosun J, Koniali L, Fitzgibbon J, Heward J(2015). Epigenetic dysregulation in follicular lymphoma . Epigenomics.

Ilott NE, Heward JA, Roux B, Tsitsiou E, Fenwick PS, Lenzi L, Goodhead I, Hertz-Fowler C, Heger A, Hall N, et al.(2015). Corrigendum: Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes . Nature communications.

Heward JA, Roux BT, Lindsay MA(2014). Divergent signalling pathways regulate lipopolysaccharide-induced eRNA expression in human monocytic THP1 cells . FEBS letters.

Heward JA, Lindsay MA(2014). Long non-coding RNAs in the regulation of the immune response . Trends in immunology.

IIott NE, Heward JA, Roux B, Tsitsiou E, Fenwick PS, Lenzi L, Goodhead I, Hertz-Fowler C, Heger A, Hall N, et al.(2014). Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes . Nature communications.