Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 250 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Isotta S.

Italy

USD 250 /hr

Oncology & Biotech Expert | Tumor Immunology | Cell-Based Assays & In Vitro Diagnostics with 8+ years of experience

Profile Summary

I am a biotech and oncology expert with a PhD in Molecular Medicine, specializing in tumor immunology, immuno-oncology and targeted cancer therapies. My research has focused on tumor-associated macrophages in breast cancer and the role of PARP inhibitors, monoclonal antibodies and NK-mediated ADCC in solid tumors, leading to high-impact scientific publications. With a background in cell-based assays, in vitro diagnostics and imaging techniques, I have hands-on experience in 3D tumor spheroids, cell characterization and immunotherapies. My expertise extends to biotech industry applications, including drug development, experimental planning and project management. I have worked as a project manager in biotech, assisting clients in research strategy, problem-solving and assay development. The projects I supported involved cutting-edge areas such as CAR-T cell therapy, antibody-drug conjugates (ADC), bi- and multi-specific antibodies, neuroscience, and gene therapy. Additionally, I have experience in mentoring students, presenting at international conferences and collaborating on innovative cancer research projects. I am available for consulting on oncology research, biotech solutions, in vitro diagnostics and scientific writing/editing.

Subject Matter Expertise

• ★ Drug Development
• ★ In vitro Diagnostics
• ★ Oncology
• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ Omics
• ☆ Metabolomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ PCR
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ RNA Sequencing
• ☆ Oligonucleotide Synthesis
• ☆ DNA Damage & Repair
• ☆ Monoclonal Antibody Production
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Histology
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Line Engineering
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Medicinal Chemistry
• ☆ Small Molecule Drug Development
• ☆ Bioanalytical Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Drug-Drug Interactions
• ☆ Preclinical Research
• ☆ Drug Efficacy Testing
• ☆ In vitro Diagnostic Design
• ☆ Immunotherapy
• ☆ Inflammation
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Project Management

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Medical Writing, General Proofreading & Editing

Research Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Analysis, Data Visualization

Product Development Product Evaluation, Quality Assurance & Control (QA/QC)

Work Experience

Project Manager

Creative Biolabs

September 2024 - January 2025

Research Associate

University of Debrecen

September 2023 - September 2024

Problem-based learning Tutor

University of Debrecen

February 2020 - July 2024

PhD Researcher

University of Debrecen

September 2019 - August 2023

Thesis Co-Supervisor

University of Debrecen

January 2021 - July 2022

Intern

Brunel University London

May 2018 - August 2018

Intern

Alma Mater Studiorum Università di Bologna

October 2016 - March 2017

Education

Ph.D.

University of Debrecen

September 2019 - September 2024

MSc

Brunel University London

September 2017 - December 2018

BSc

Alma Mater Studiorum, Università di Bologna

September 2013 - July 2017

High School Diploma

Liceo Classico Statale Marco Minghetti (Bologna)

September 2008 - July 2013

Certifications

• Certificate of Poster and Oral Presentation "PARP: Research on the family of poly(ADP-ribose)polymerases"

  FEBS

  June 2023 - Present

• Certificate of Recognition for work as Supervisor

  OTDK-The 36th National Scientific Student Conference, Medical and Health Sciences, Budapest

  April 2023 - Present

• FEBS Youth Travel Grant Award to attend the FEBS Advanced Course "PARP 2023" in Hvar, Croatia (June 4th-8th 2023)

  FEBS-Federation of European Biochemical Societies

  March 2023 - Present

• Certificate of Poster Presentation "Hungarian Molecular Life Sciences Conference"

  Diamond Congress Ltd

  March 2023 - Present

• Certificate of Oral and Poster Presentation "Redox Alteration and Cellular Responses: from Signalling to Interventions"

  SFRR-E

  September 2022 - Present

• Certificate of Poster Presentation "Annual Meeting of the Hungarian Biochemical Society"

  Diamond Congress Ltd

  August 2022 - Present

• SFRR-Europe Grant to attend the FEBS Advanced Course "Redox Alteration and Cellular Responses: from Signalling to Interventions" in Spetses Island, Greece (September 19th-25th 2022)

  SFRR-Europe

  June 2022 - Present

• Certificate of Poster Presentation "Hungarian Molecular Life Sciences Conference"

  Diamond Congress Ltd

  November 2021 - Present

• Certificate of Completion "CamBioScience: Discovering Organoids: Intestinal & Cerebral"

  Obrizum

  June 2020 - Present

• Certificate of Attendance "Basic Life Support and Defibrillation-Italian Resuscitation Council (IRC)"

  European Research Council (ERC)

  January 2015 - Present

• IELTS CERTIFICATE

  British Council

  July 2017 - July 2019

Publications

JOURNAL ARTICLE

Sturniolo I, Váróczy C, Bede ÁM, Hegedűs C, Demény MÁ, Virág L (2024). Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery . Journal of visualized experiments : JoVE.

Sturniolo I, Váróczy C, Regdon Z, Mázló A, Szabolcs Muzsai, Bácsi A, Intili G, Csaba Hegedűs, Mark Boothby, Holechek J, et al. (2024). PARP14 Contributes to the Development of the Tumor-Associated Macrophage Phenotype . International journal of molecular sciences.

Guti E, Regdon Z, Sturniolo I, Kiss A, Kovács K, Demény M, Arpad Szoor, Vereb G, Szöllősi J, Hegedűs C, et al. (2022). The multitargeted receptor tyrosine kinase inhibitor sunitinib induces resistance of HER2 positive breast cancer cells to trastuzumab-mediated ADCC . Cancer immunology, immunotherapy : CII.

Kiss A, Ráduly AP, Regdon Z, Zsuzsanna Polgar, Szabolcs Tarapcsak, PhD, Sturniolo I, Tarek El-Hamoly, László Virág, Csaba Hegedűs (2020). Targeting Nuclear NAD⁺ Synthesis Inhibits DNA Repair, Impairs Metabolic Adaptation and Increases Chemosensitivity of U-2OS Osteosarcoma Cells . Cancers.

Kumar J, Murugaiah V, Sotiriadis G, Kaur A, Jeyaneethi J, Sturniolo I, Fatimah S. Alhamlan, Chatterjee J, Hall M, Kishore U, et al. (2019). Surfactant Protein D as a Potential Biomarker and Therapeutic Target in Ovarian Cancer . Frontiers in oncology.