Biomedical Scientist & Toxicology Researcher | Psychedelic Science, Transpersonal Psychology & Scientific Writing.

Marcel Nogueira, Solimary García-Hernández, Gleicy Sotéro Roberto, Daniel Cardoso Rodrigues (2026). Regulatory ambiguity and governance challenges for psilocybin mushrooms in Brazil . International Journal of Drug Policy.

Marcel Nogueira, Solimary García-Hernández, Gleicy Sotéro Roberto, Leonardo Zanella Marques (2024). Psilocybin mushrooms and public health in Brazil: a low-risk adverse event profile calls for evidence-based regulatory discussions .

GLEICY ROBERTO, Nathalia de Oliveira Meireles da Costa, Nathalia de Oliveira Meireles da Costa, Luís Felipe Ribeiro Pinto (2022). Evaluation of the expression profile of the components of the PI3K/AKT pathway and the functional role of PIK3R3 in esophageal squamous cell carcinoma.

GLEICY ROBERTO(2021). EVALUATION OF THE ROLE OF AUTOPHAGIA IN THE PROGRESSION AND THERAPEUTIC RESPONSE OF ESOPHAGAL SPIDERMID CARCINOMA . Episteme Transversalis. 12. (1).

GLEICY ROBERTO, Luis Felipe Ribeiro Pinto, Nathalia de Oliveira Meireles da Costa (2021). Evaluation of the expression profile of the components of the PI3K/AKT pathway and the functional role of PIK3R3 in esophageal squamous cell carcinoma.

GLEICY ROBERTO, Pedro Nicolau Neto, Luis Felipe Ribeiro Pinto (2020). Analysis of EPCAM and PROM1 gene expression in Laryngeal Squamous Carcinoma.

GLEICY ROBERTO, Luis Felipe Ribeiro Pinto, Nathalia de Oliveira Meireles da Costa (2020). Evaluation of the Role of GABARAPL1 in Autophagy Rates and Esophageal Squamous Carcinoma (EEC) Progression.

Esophageal cancer (EC) represents the eighth most incident tumor and the sixth most deadly of all malignant tumors worldwide. Esophageal squamous cell carcinoma (ESCC) represents 90% of cases of EC. The high lethality of ESCC is a consequence, mainly, of the late diagnosis of these tumors. Understanding the mechanisms involved in the deregulation of the cellular and molecular processes involved in the development of this tumor can lead to the identification of altered pathways, revealing potential new therapeutic targets. In this context, autophagy appears as an interesting study target for ESCC, due to the stresses arising from the tumor microenvironment being fundamental for tumor progression and understanding the deprivation of nutrients, hypoxia, detachment of the extracellular matrix, among others, which are capable of trigger autophagy. Studies have observed an association between autophagy, response to treatment and, consequently, patients' prognosis. Thus, molecules involved in autophagy have been proposed as biomarkers of prognosis and / or therapeutic response, and this process has been raised as a promising therapeutic target. In this sense, due to the few studies on the role of autophagy in the treatment of ESCC, this has become the focus of this present work.