Profile Details

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Hire Dr. Gene C C K.

United Kingdom

USD 45 /hr

Experienced PhD Research Associate in Cancer Genomics, DNA damage/repair, CRISPR/Cas9 Genome Editing; Freelance editor

Profile Summary

Gene worked as a licensed Biomedical Scientist before he obtained his MSc from Universität Heidelberg with a major in Systems Biology and trained in mass spectrometry-based proteomics under Prof Ruedi Aebersold at ETH Zürich. Bored of the snow in Switzerland, he then traded it for the rain in the UK to pursue his PhD at the Wellcome Trust Sanger Institute, University of Cambridge, UK. His PhD work focuses on DNA damage/repair, mutagenesis, and cancer. He uses experimental systems to delineate how mutational processes leave characteristic patterns in the genome. Particularly, he’s passionate about combining molecular biology techniques, such as CRISPR/Cas9, with ‘omic’ sequencing technologies to understand how DNA damage and repair processes jointly shape the mutational landscape in human cancers. When he’s not editing cells in the lab, he’s likely wrestling with a piece of R code in front of his computer. He's published articles in high-impact journals, and is currently working as a research associate at the University of Cambridge, UK.

Subject Matter Expertise

• ★ Genomics
• ★ DNA Sequencing
• ★ Gene Editing/CRISPR
• ☆ Genetics
• ☆ Proteomics
• ☆ Genome Sequencing
• ☆ Mutagenesis
• ☆ Genetic Engineering
• ☆ Cancer Research
• ☆ Scientific Proofreading & Editing

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing

Research Market Research, Gap Analysis, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

Work Experience

Post-doctoral Research Associate Fellow

Hutchison MRC Cancer Unit/University of Cambridge, UK

January 2019 - Present

Education

PhD in Biological Sciences (Genomics)

University of Cambridge, United Kingdom

January 2015 - January 2019

Certifications

• PhD

  University of Cambridge

  October 2015 - January 2020

Publications

JOURNAL ARTICLE

Gene Koh, Andrea Degasperi, Xueqing Zou, Sophie Momen, Serena Nik-Zainal(2021). Mutational signatures: emerging concepts, caveats and clinical applications . Nature Reviews Cancer. Springer Science and Business Media {LLC}

Gene Koh, Xueqing Zou, Serena Nik-Zainal(2020). Mutational signatures: experimental design and analytical framework . Genome Biology. 21. (1). Springer Science and Business Media {LLC}

Ilias Georgakopoulos-Soares, Gene Koh, Sophie E. Momen, Josef Jiricny, Martin Hemberg, Serena Nik-Zainal(2020). Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts . Nature Communications. 11. (1). Springer Science and Business Media {LLC}

Andrea Degasperi, Tauanne Dias Amarante, Jan Czarnecki, Scott Shooter, Xueqing Zou, Dominik Glodzik, Sandro Morganella, Arjun S. Nanda, Cherif Badja, Gene Koh, et al.(2020). Author Correction: A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies . Nature Cancer. 1. (7). p. 748--748. Springer Science and Business Media {LLC}

Andrea Degasperi, Tauanne Dias Amarante, Jan Czarnecki, Scott Shooter, Xueqing Zou, Dominik Glodzik, Sandro Morganella, Arjun S. Nanda, Cherif Badja, Gene Koh, et al.(2020). A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies . Nature Cancer. 1. (2). p. 249--263. Springer Science and Business Media {LLC}

Li Li, Ching Chiek Koh, Daniel Reker, J. B. Brown, Haishuai Wang, Nicholas Keone Lee, Hien-haw Liow, Hao Dai, Huai-Meng Fan, Luonan Chen, et al.(2019). Predicting protein-ligand interactions based on bow-pharmacological space and Bayesian additive regression trees . Scientific Reports. 9. (1). Springer Science and Business Media {LLC}