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Hire Dr. Hiren K.

United States

USD 125 /hr

Computational Biology & AI-driven Decision Support Systems in the Health Care Domain

Profile Summary

A recognized thought leader in Translational Computational Biology and Bioinformatics, bringing over 13 years of post-PhD experience in driving data-intensive translational insights from integrated multi-OMICS data. I spearhead the engineering and deployment of scalable data integration solutions on AWS & GCP Clouds, driving the adoption of state-of-the-art computational techniques, including AI/ML-powered feature extraction and LLM-based knowledge inference. This work directly contributes to enhanced patient stratification, predictive modeling, and the clinical development of precision therapies, aligning with the mission to power deeper understanding in healthcare.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Molecular Biology
• ☆ Omics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ Genomics
• ☆ Synthetic Genomics
• ☆ Data Analysis
• ☆ Machine Learning
• ☆ Artificial Intelligence
• ☆ Bioinformatics
• ☆ Systems Biology
• ☆ Python
• ☆ R
• ☆ Drug Development
• ☆ Pharmacogenomics
• ☆ Public Health
• ☆ Epidemiology
• ☆ Pandemic Preparedness
• ☆ Global Health
• ☆ Disease Control And Prevention
• ☆ Quality of Life Assessment
• ☆ Health Technology Assessment
• ☆ E-Health & Telemedicine
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Survey Design & Methodology
• ☆ Meta-Research
• ☆ Feasibility Studies
• ☆ Technology Scouting
• ☆ Literature Search
• ☆ Gap Analysis
• ☆ Gray Literature Search
• ☆ Skills Training

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Technical Writing

Research User Research, Meta-Research, Feasibility Study, Technology Scouting, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Business Strategy Consulting, Digital Strategy Consulting, Healthcare Consulting, Operations Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

Product Development Formulation, Stability/Shelf Life Testing, Quality Assurance & Control (QA/QC), Concept Development, Reverse Engineering

Work Experience

Postdoc -Research Associate

University of Maryland

February 2014 - Present

Bioinformatics manager

Frederick National Laboratory for Cancer Research

February 2024 - January 2026

Staff Scientists

NIH

January 2020 - August 2021

Scientist

CosmosID Inc.

March 2018 - December 2019

Senior Research Associate and Technical Lead

Genome Life Sciences

June 2013 - January 2014

PhD Research Scholar

Universitat de Lleida Facultat de Medicina

June 2008 - May 2013

Lecturer

Amity University Rajasthan

August 2006 - July 2008

Research Scientist

Institute of Bioinformatics

March 2005 - July 2006

Technical Consultant Bioinformatics

Applitech Solution

July 2004 - February 2005

Lecturer

Virani Science College

June 2001 - May 2002

Education

PhD - Integrated Molecular Systems Biology (Dept. of Basic Medical Sciences)

Ph.D - University of Lleida

2008 - 2012

MSc - Bioinformatics (Bioinformatics)

M.Sc Bioinformatics - Sikkim Manipal University Directorate of Distance Education

- 2004

MSc - Biomedical Technology (School of Sciences)

M.Sc Biomedical Technology - Gujarat University

- 2001

BSc (Hon). Biochemistry (Biochemistry)

B.Sc Biochemistry - Virani Science College

- 1999

Certifications

• Higher Diploma Software Engineering

  APTECH

  June 1996 - July 1998

Publications

JOURNAL ARTICLE

Noam Auslander, Daniel M Ramos, Ivette Zelaya, Hiren Karathia, Thomas O. Crawford, Alejandro A Schäffer, Charlotte J Sumner, Eytan Ruppin(2020). The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases . Molecular Systems Biology. 16. (12). {EMBO}

(2020). Multi-omics analysis reveals the influence of genetic and environmental risk factors on developing gut microbiota in infants at risk of celiac disease . Microbiome.

(2020). Multiple NDM-5-Expressing Escherichia Coli Isolates From an Immunocompromised Pediatric Host . Open forum infectious diseases.

Auslander, N., Ramos, D.M., Zelaya, I., Karathia, H., Crawford, T.O., Schäffer, A.A., Sumner, C.J., Ruppin, E.(2020). The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases . Molecular Systems Biology. 16. (12).

Leonard, M.M., Karathia, H., Pujolassos, M., Troisi, J., Valitutti, F., Subramanian, P., Camhi, S., Kenyon, V., Colucci, A., Serena, G., et al.(2020). Multi-omics analysis reveals the influence of genetic and environmental risk factors on developing gut microbiota in infants at risk of celiac disease . Microbiome. 8. (1).

Flerlage, T., Brazelton de Cardenas, J.N., Garner, C.D., Hasan, N.A., Karathia, H., Qudeimat, A., Maron, G., Hayden, R.(2020). Multiple NDM-5-expressing Escherichia coli isolates from an immunocompromised pediatric host . Open Forum Infectious Diseases. 7. (2).

Moye, Z.D., Das, C.R., Tokman, J.I., Fanelli, B., Karathia, H., Hasan, N.A., Marek, P.J., Senecal, A.G., Sulakvelidze, A.(2020). Treatment of fresh produce with a Salmonella-targeted bacteriophage cocktail is compatible with chlorine or peracetic acid and more consistently preserves the microbial community on produce . Journal of Food Safety. 40. (2).

(2019). Prosthetic joint infections present diverse and unique microbial communities using combined whole-genome shotgun sequencing and culturing methods . Journal of medical microbiology.

(2019). UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma . Cell.

Wolf, Y., Bartok, O., Patkar, S., Eli, G.B., Cohen, S., Litchfield, K., Levy, R., Jiménez-Sánchez, A., Trabish, S., Lee, J.S., et al.(2019). UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma . Cell. 179. (1). p. 219-235.e21.

Weaver, A.A., Hasan, N.A., Klaassen, M., Karathia, H., Colwell, R.R., Shrout, J.D.(2019). Prosthetic joint infections present diverse and unique microbial communities using combined whole-genome shotgun sequencing and culturing methods . Journal of medical microbiology. 68. (10). p. 1507-1516.

(2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures . Cell.

Lee, J.S., Adler, L., Karathia, H., Carmel, N., Rabinovich, S., Auslander, N., Keshet, R., Stettner, N., Silberman, A., Agemy, L., et al.(2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures . Cell. 174. (6). p. 1559-1570.e22.

(2016). A pathway-centric view of spatial proximity in the 3D nucleome across cell lines . Scientific reports.

Karathia, H., Kingsford, C., Girvan, M., Hannenhalli, S.(2016). A pathway-centric view of spatial proximity in the 3D nucleome across cell lines . Scientific Reports. 6.

Anabel Usie, Hiren Karathia, Ivan Teixidó, Rui Alves, Francesc Solsona(2014). Biblio-MetReS for user-friendly mining of genes and biological processes in scientific documents . PeerJ. 2. p. e276. {PeerJ}

Usie, A., Karathia, H., Teixidó, I., Alves, R., Solsona, F.(2014). Biblio-metReS for user-friendly mining of genes and biological processes in scientific documents . PeerJ. 2014. (1).

Jordi Vilaplana, Francesc Solsona, Ivan Teixido, Anabel Usié, Hiren Karathia, Rui Alves, Jordi Mateo(2014). Database Constraints Applied to Metabolic Pathway Reconstruction Tools . The Scientific World Journal. 2014. p. 1--12. Hindawi Limited

Vilaplana, J., Solsona, F., Teixido, I., Usié, A., Karathia, H., Alves, R., Mateo, J.(2014). Database constraints applied to metabolic pathway reconstruction tools . Scientific World Journal. 2014.

Baldiri Salvado, Ester Vilaprinyo, Hiren Karathia, Albert Sorribas, Rui Alves, Mark Isalan(2012). Two Component Systems: Physiological Effect of a Third Component . PLoS ONE. 7. (2). p. e31095. Public Library of Science ({PLoS})

(2012). Two component systems: physiological effect of a third component . PLoS One.

Salvado, B., Vilaprinyo, E., Karathia, H., Sorribas, A., Alves, R.(2012). Two component systems: Physiological effect of a third component . PLoS ONE. 7. (2).

(2011). Biblio-MetReS: A bibliometric network reconstruction application and server. BMC Bioinformatics.

Baldiri Salvado, Hiren Karathia, Anabel Usie Chimenos, Ester Vilaprinyo, Stig Omholt, Albert Sorribas, Rui Alves(2011). Methods for and results from the study of design principles in molecular systems . Mathematical Biosciences. 231. (1). p. 3--18. Elsevier {BV}

Salvado, B., Karathia, H., Chimenos, A.U., Vilaprinyo, E., Omholt, S., Sorribas, A., Alves, R.(2011). Methods for and results from the study of design principles in molecular systems . Mathematical Biosciences. 231. (1). p. 3-18.

Usié, A., Karathia, H., Teixidó, I., Valls, J., Faus, X., Alves, R., Solsona, F.(2011). Biblio-MetReS: A bibliometric network reconstruction application and server . BMC Bioinformatics. 12.

Salvado, B., Karathia, H., Chimenos, A. U., Vilaprinyo, E., Omholt, S., Sorribas, A., Alves, R.(2011). Methods for and results from the study of design principles in molecular systems . Math Biosci. 231. (1). p. 3-18.

Karathia, H., Vilaprinyo, E., Sorribas, A., Alves, R.(2011). Saccharomyces cerevisiae as a model organism: A comparative study . PLoS ONE. 6. (2).

Karathia, H., Vilaprinyo, E., Sorribas, A., Alves, R.(2011). Saccharomyces cerevisiae as a model organism: a comparative study . PLoS One. 6. (2). p. e16015.

MISHRA, GR, SURESH, M, KUMARAN, K, KANNABIRAN, N, SURESH, S, BALA, P, SHIVAKUMAR, K, ANURADHA, N, REDDY, R, RAGHAVAN, TM, et al.(2006). Human protein reference database - 2006 update . NUCLEIC ACIDS RESEARCH. 34. p. D411-D414.

Mishra, G.R., Suresh, M., Kumaran, K., Kannabiran, N., Suresh, S., Bala, P., Shivakumar, K., Anuradha, N., Reddy, R., Raghavan, T.M., et al.(2006). Human protein reference database--2006 update . Nucleic acids research. 34. (Database issue).

OTHER

Justin Malin, Daphne Ezer, Xiaoyan Ma, Steve Mount, Hiren Karathia, Seung Gu Park, Boris Adryan, Sridhar Hannenhalli(2015). Crowdsourcing: Spatial clustering of low-affinity binding sites amplifies in vivo transcription factor occupancy . Cold Spring Harbor Laboratory

CONFERENCE PAPER

Ivan Teixidó, Anabel Usié, Josep Ll. Lérida, Francesc Solsona, Jorge Comas, Nestor Torres, Hiren Karathia, Rui Alves(2013). P-Biblio-MetReS, a parallel data mining tool for the reconstruction of molecular networks . Proceedings of the 20th European MPI Users' Group Meeting on - EuroMPI '13. {ACM} Press

Teixidó, I., Usié, A., Lérida, J.L., Solsona, F., Comas, J., Torres, N., Karathia, H., Alves, R.(2013). P-Biblio-MetReS, a parallel data mining tool for the reconstruction of molecular networks . ACM International Conference Proceeding Series. p. 247-252.