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Hire Dr. Chinedu A.

United Kingdom

USD 100 /hr

Computational Biology | Bioinformatics | Genomics | Biostatistics | Molecular Biology

Profile Summary

Data analysis, bioinformatics and molecular biology skills

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Omics
• ☆ Cell Biology
• ☆ Data Analysis
• ☆ Machine Learning
• ☆ Neural Networks
• ☆ Deep Learning
• ☆ Statistics
• ☆ Bioinformatics
• ☆ R
• ☆ Medical Sciences
• ☆ Cancer Research
• ☆ Course Content Writing

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Digital Strategy Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Algorithm Design-Non ML, Data Visualization, Big Data Analytics, Data Processing, Data Insights

Product Development Formulation, Product Evaluation, Material Sourcing, Product Validation, Manufacturing, Concept Development, Prototyping

Work Experience

Senior Lecturer

Leeds Beckett University

- Present

Honorary lecturer in Bioinformatics

Queen Mary University of London

November 2022 - Present

Lecturer in Biomedical Science

London South Bank University

November 2021 - February 2023

BIoinformatician

Queen Mary University of London

January 2019 - November 2021

Postdoctoral Researcher

Queen Mary University of London

November 2017 - November 2021

Education

PhD Molecular and Cell Biology (School of Pharmacy and Medical Sciences,)

University of Bradford

January 2014 - December 2017

Masters in Biomedical Sciences (Biomedical Sciences)

University of Bradford

August 2012 - December 2013

Certifications

• Neural Networks and Deep Learning

  coursera

  https://www.coursera.org/account/accomplishments/verify/N3VB5F7BDEUC

  March 2019 - Present

Publications

JOURNAL ARTICLE

Molly R. Patterson, Joseph A. Cogan, Rosa Cassidy, Daisy A. Theobald, Miao Wang, James A. Scarth, Chinedu A. Anene, Adrian Whitehouse, Ethan L. Morgan, Andrew Macdonald (2024). The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer . Nature Communications.

Platelet-derived microvesicles isolated from type-2 diabetes mellitus patients harbour an altered miRNA signature and drive MDA-MB-231 triple-negative breast cancer cell invasion @article{Tutuianu_2024, title={Platelet-derived microvesicles isolated from type-2 diabetes mellitus patients harbour an altered miRNA signature and drive MDA-MB-231 triple-negative breast cancer cell invasion}, volume={19}, ISSN={1932-6203}, url={http://dx.doi.org/10.1371/journal.pone.0304870}, DOI={10.1371/journal.pone.0304870}, number={6}, journal={PLOS ONE}, publisher={Public Library of Science (PLoS)}, author={Tutuianu, Anca and Anene, Chinedu A. and Shelton, Mikayla and Speirs, Valerie and Whitelaw, Donald C. and Thorpe, Joanne and Roberts, Wayne and Boyne, James R.}, editor={Chen, Suzie}, year={2024}, month=jun, pages={e0304870} } . PLOS ONE.

Cumulative incidence and risk factors for cutaneous squamous cell carcinoma metastases in organ transplant recipients: The Skin Care in Organ Transplant Patients in Europe-International Transplant Skin Cancer Collaborative metastases study, a prospective multicenter study @article{de_Jong_2024, title={Cumulative incidence and risk factors for cutaneous squamous cell carcinoma metastases in organ transplant recipients: The Skin Care in Organ Transplant Patients in Europe-International Transplant Skin Cancer Collaborative metastases study, a prospective multicenter study}, volume={90}, ISSN={0190-9622}, url={http://dx.doi.org/10.1016/j.jaad.2024.01.040}, DOI={10.1016/j.jaad.2024.01.040}, number={6}, journal={Journal of the American Academy of Dermatology}, publisher={Elsevier BV}, author={de Jong, Estella and Genders, Roel and Harwood, Catherine A. and Green, Adèle C. and Plasmeijer, Elsemieke I. and Proby, Charlotte and Geissler, Edward and Ferrándiz-Pulido, Carla and Ducroux, Emilie and Euvrard, Sylvie and Geusau, Alexandra and Jahn-Bassler, Karin and Borik-Heil, Liliane and Rácz, Emõke and Nägeli, Mirjam and Hofbauer, Günther F.L. and Piaserico, Stefano and Russo, Irene and Mackintosh, Lorna and Borges-Costa, João and Angeliki-Gkini, Maria and Zavattaro, Elisa and Savoia, Paola and Imko-Walszuk, Beata and Dębska-Slizień, Alicja and Garmyn, Marjan and van Kelst, Sofie and Ricar, Jan and Cetkovska, Petra and Matin, Rubeta and Güleç, Ayşe Tülin and Seçkin, Deniz and Anene, Chinedu Anthony and Oliveira, Walmar R.P. and Rademaker, Marius and Goeman, Jelle and van Geloven, Nan and Ruiz, Emily and Murad, Fadi and Karn, Emily and Schmults, Chrysalyne D. and Bouwes Bavinck, Jan Nico}, year={2024}, month=jun, pages={1200–1209} } . Journal of the American Academy of Dermatology.

Wang J, Harwood CA, Bailey E, Bewicke-Copley F, Anene CA, Thomson J, Qamar MJ, Laban R, Nourse C, Schoenherr C, et al. (2023). Transcriptomic analysis of cutaneous squamous cell carcinoma reveals a multi-gene prognostic signature associated with metastasis . Journal of the American Academy of Dermatology.

Wang J, Harwood CA, Bailey E, Bewicke-Copley F, Chinedu Anthony Anene, Thomson J, Qamar MJ, Laban R, Nourse C, Schoenherr C, et al. (2023). Transcriptomic analysis of cutaneous squamous cell carcinoma reveals a multi-gene prognostic signature associated with metastasis . Journal of the American Academy of Dermatology.

Katherine L Harper, Timothy J Mottram, Chinedu A Anene, Becky Foster, Molly R Patterson, Euan McDonnell, Andrew Macdonald, David Westhead, Adrian Whitehouse(2022). Dysregulation of the miR‐30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication . EMBO reports. {EMBO}

Harper, K.L., Mottram, T.J., Chinedu Anthony Anene, Foster, B., Patterson, M.R., McDonnell, E., Macdonald, A., Westhead, D., Whitehouse, A. (2022). Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication . EMBO Reports.

Chinedu Anthony Anene, Taggart, E., Harwood, C., Pennington, D.J., Wang, J. (2022). Decosus: An R Framework for Universal Integration of Cell Proportion Estimation Methods . Frontiers in genetics.

Bi, O., Chinedu Anthony Anene, Nsengimana, J., Roberts, W., Newton-Bishop, J., Boyne, J.R. (2021). SFPQ promotes an oncogenic transcriptomic state in melanoma . Oncogene.

Jason Thomson, Findlay Bewicke-Copley, Chinedu Anthony Anene, Abha Gulati, Ai Nagano, Karin Purdie, Gareth J. Inman, Charlotte M. Proby, Irene M. Leigh, Catherine A. Harwood, et al.(2021). The Genomic Landscape of Actinic Keratosis . Journal of Investigative Dermatology. 141. (7). p. 1664--1674.e7. Elsevier {BV}

Chinedu Anthony Anene, Khan F., Bewicke-Copley, F., Maniati, E., Wang, J. (2021). ACSNI: An unsupervised machine-learning tool for prediction of tissue-specific pathway components using gene expression profiles . Patterns.

Chinedu Anthony Anene, Faraz Khan, Findlay Bewicke-Copley, Eleni Maniati, Jun Wang (2021). ACSNI: An unsupervised machine-learning tool for prediction of tissue-specific pathway components using gene expression profiles . Patterns.

Thomson, J., Bewicke-Copley, F., Chinedu Anthony Anene, Gulati, A., Nagano, A., Purdie, K., Inman, G.J., Proby, C.M., Leigh, I.M., Harwood, C.A., et al. (2021). The Genomic Landscape of Actinic Keratosis . The Journal of Investigative Dermatology.

Shelton, M., Chinedu Anthony Anene, Nsengimana, J., Roberts, W., Newton-Bishop, J., Boyne, J.R. (2021). The role of CAF derived exosomal microRNAs in the tumour microenvironment of melanoma . Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.

Shelton, M., Anene, C. A., Nsengimana, J., Roberts, W., Newton-Bishop, J., Boyne, J. R. (2021). The role of CAF derived exosomal microRNAs in the tumour microenvironment of melanoma . Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.

Thomson, Jason, Bewicke-Copley, Findlay, Anene, Chinedu Anthony, Gulati, Abha, Nagano, Ai, Purdie, Karin, Inman, Gareth J., Proby, Charlotte M., Leigh, Irene M., Harwood, Catherine A., et al. (2021). The Genomic Landscape of Actinic Keratosis . Journal of Investigative Dermatology.

Dobson, S.J., Chinedu Anthony Anene, Boyne, J.R., Mankouri, J., Macdonald, A., Whitehouse, A (2020). Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility . Biochemical Journal.

Uyulur, Firat, Bewicke-Copley, Findlay, Anene, Chinedu Anthony, Schlesner, Matthias, Siebert, Reiner, Okosun, Jessica, Fitzgibbon, Jude, Wang, Jun (2020). Systematic Evaluation of Somatic Cis-Regulatory Mutations in Follicular Lymphoma . Blood.

Dobson, Samuel J., Anene, Anthony, Boyne, James R., Mankouri, Jamel, Macdonald, Andrew, Whitehouse, Adrian (2020). Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility . Biochemical Journal.

(2019). BSCR Autumn Meeting Abstracts . Cardiovascular Drugs and Therapy.

Chinedu Anthony Anene, Graham, A.M., Boyne, J., Roberts, W. (2018). Platelet microparticle delivered microRNA-Let-7a promotes the angiogenic switch . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

Anene, C., Graham, A.M., Boyne, J. and Roberts, W., 2018. Platelet microparticle delivered microRNA-Let-7a promotes the angiogenic switch. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1864(8), pp.2633-2643 .

Chinedu Anene, John G. Foster, Rebecca Arkell, Marco Del Giudice, Andrea Lauria, John D. Kelly, Nicholas R. Lemoine, Salvatore Oliviero, Matteo Cereda, Prabhakar Rajan (2018). Dysregulation of splicing-related proteins in prostate cancer is controlled by FOXA1 . BioRxiv.

Anene, Chinedu, Graham, Anne M., Boyne, James, Roberts, Wayne (2018). Platelet microparticle delivered microRNA-Let-7a promotes the angiogenic switch . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

PREPRINT

Pseudouridine prevalence in Kaposi’s sarcoma-associated herpesvirus transcriptome reveals an essential mechanism for viral replication @article{PPR:PPR610318, title = {Pseudouridine prevalence in Kaposi’s sarcoma-associated herpesvirus transcriptome reveals an essential mechanism for viral replication}, author = {Mottram TJ and Harper KL and Vasconcelos EJR and Anene CA and Whitehouse A}, doi = {10.1101/2023.01.31.526461} } .

John G Foster, Esteban Gea, Mosammat A Labiba, Chinedu A Anene, Jacqui Stockley, Celine Philippe, Matteo Cereda, Kevin Rouault-Pierre, Hing Leung, Conrad Bessant, et al.(2022). HNRNPA2B1 controls an unfolded protein response-related prognostic gene signature in prostate cancer . Cold Spring Harbor Laboratory

Harper KL, Mottram TJ, Anene CA, Foster B, Patterson MR, McDonnell E, Macdonald A, Westhead D, Whitehouse A(2021). CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication .

SOFTWARE

(2022). ACSNI .

(2022). Decosus .

(2019). miRNAprimer .

CONFERENCE PAPER

Firat U., Bewicke-Copley, F., Chinedu Anthony Anene, Schlesner, M., Icgc MMML-Seq Project3, Siebert, R., Okosun, J., Fitzgibbon, J., Wang, J (2020). Systematic Evaluation of Somatic Cis-Regulatory Mutations in Follicular Lymphoma .

CONFERENCE POSTER

Rashed, Al-Hammad, Chinedu Anthony Anene, Graham, A.M., Roberts, W. (2015). Platelet induced hepatocellular carcinoma HEPG2 cell proliferation and angiogenic potential is integrin IIb3 dependent . Platelets.