Profile Details

Contact

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Hire Dr. Brian W.

Profile Summary

I am an experienced PhD. (Biochemistry/Molecular Biology) researcher with 10+ years postdoctoral experience in academic cancer research, and 5+ years in stem cell research. I am currently a faculty member of Harvard Medical School at the Boston Children's Hospital, USA. I have published over 20 peer-reviewed manuscripts (11 as first author) in journals including Nature, Cancer Research, Oncogene, Cell Metabolism, Molecular Endocrinology, Genes and Development, EMBO, amongst others. These total 1000+ citations overall. The primary focus of my career has been elucidating gene deregulation that leads to carcinogenesis (e.g. breast, colorectal, melanoma). From initial focus on particular transcription factors, and understanding of how they are controlled via signal transduction networks, to broader genomics-network bioinformatic analyses, I have gained a lot of insight through having the opportunity of working with some of the best people in science. My current focus is on cancer stem cells, within the group of Markus Frank (the discoverer of melanoma stem cells) and defining exactly what makes them carcinogenic relative to the non-carcinogenic "bulk" population of cells in a tumor. This also allows me to work on chemotherapy-resistance in cancer, and utilize patient-derived samples. Furthermore, we also work on normal physiologic stem cells from various sources with an eye to developing stem cell therapies. I believe my work will yield something clinically-relevant, and is not just "science for the sake of science". For example, refer to either following link (or the Cell Stem Cell pdf below) to an article highlighting our recent collaboration with Pharma (of which I was actively involved) to develop a therapeutic for Phase I clinical trials: http://dx.doi.org/10.1016/j.stem.2012.11.020 http://www.sciencedirect.com/science/article/pii/S1934590912006546 Thanks for taking the time to browse my profile. I appreciate we are all pretty busy. Cheers, Brian.

Subject Matter Expertise

• ☆ Genetics
• ☆ Cell Signaling Pathways
• ☆ Stem Cell Research
• ☆ Pharmaceutical Sciences
• ☆ Skin Cancer
• ☆ Oncology
• ☆ Colorectal Cancer
• ☆ Cancer Research
• ☆ Carcinogenesis
• ☆ Audio Transcription

Services

• Writing
• Consulting
• Data & AI
• Product Development

Work Experience

Instructor of Pediatrics (Staff Scientist)

Harvard Medical School

February 2013 - February 2015

Research Fellow

Harvard Medical School

February 2009 - February 2013

Postdoctoral Fellow

McGill University Cancer Centre

February 2003 - February 2009

Education

PhD.

University of Dundee

January 2003 - January 2003

Certifications

• Certification details not provided.