Profile Details

Create Project

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Hire Bethany A. K.

United States

Academic Writer and Researcher with 15+ Years of Experience

Profile Summary

Dr. Bethany Kerr works to understand how cancers metastasize or spread to the bone. She utilizes cancer cell biology, live imaging, animal models, and tissue-engineered models to uncover the mechanisms controlling metastasis to develop new treatments to prevent the spread of cancer. She is an Assistant Professor at the Wake Forest School of Medicine in the Departments of Cancer Biology, Orthopaedic Surgery, Biomedical Engineering, and Urology and is a member of the Wake Forest Baptist Comprehensive Cancer Center. She has received several awards for her academic work and has been funded by an NIH F32 Individual NRSA, an NIH K99/R00 Pathway to Independence Award, a Pardee Foundation Award, and a Metavivor Research Award. Dr. Kerr has a B.E. double majoring in Biomedical Engineering and Chemical Engineering from Vanderbilt University and a Ph.D. in Regenerative Medicine from Thomas Jefferson University.

Subject Matter Expertise

• ★ Cancer Research
• ★ Research Methodology
• ★ Technical & Scientific Writing
• ☆ Biomarkers
• ☆ Histology
• ☆ Biological Engineering

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting

Research Market Research, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Product Development Formulation

Work Experience

Wake Forest University School of Medicine

December 2015 - Present

Project Staff

Cleveland Clinic

June 2008 - November 2015

Education

Ph.D. (Tissue Engineering and Regenerative Medicine)

Thomas Jefferson University

2002 - 2008

B.E. (Biomedical Engineering and Chemical Engineering)

Vanderbilt University

1998 - 2002

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Bethany A. Kerr, Koran S. Harris, Lihong Shi, Brittni M. Foster, Mary E. Mobley, Phyllis L. Elliott, Conner J. Song, Kounosuke Watabe, Carl D. Langefeld (2021). CD117/c-kit defines a prostate CSC-like subpopulation driving progression and TKI resistance . Scientific Reports.

Bethany A. Kerr, Lihong Shi, Alexander H. Jinnah, Koran S. Harris, Jeffrey S. Willey, Donald P. Lennon, Arnold I. Caplan, Tatiana V. Byzova(2021). Kindlin-3 mutation in mesenchymal stem cells results in enhanced chondrogenesis . Experimental Cell Research. 399. (2). p. 112456. Elsevier {BV}

Bethany A. Kerr, Lihong Shi, Alexander H. Jinnah, Koran S. Harris, Jeffrey S. Willey, Donald P. Lennon, Arnold I. Caplan, Tatiana V. Byzova(2021). Kindlin-3 mutation in mesenchymal stem cells results in enhanced chondrogenesis . Experimental Cell Research. p. 112456. Elsevier {BV}

(2019). Aging is just a state of marrow . Science Translational Medicine.

(2019). A workout plan to prevent metastasis . Science Translational Medicine.

(2019). An aspirin a day keeps metastasis at bay . Science Translational Medicine.

(2019). Knee and Hip Joint Cartilage Damage from Combined Spaceflight Hazards of Low-Dose Radiation Less than 1 Gy and Prolonged Hindlimb Unloading . Radiation Research.

(2018). Emerging and Established Models of Bone Metastasis . Cancers.

Brittni Foster, Danish Zaidi, Tyler Young, Mary Mobley, Bethany Kerr(2018). CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance . Biomedicines. 6. (1). p. 31. {MDPI} {AG}

(2018). CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance . Biomedicines.

(2018). CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance . Biomedicines.

Jinnah, A.H., Zacks, B.C., Gwam, C.U., Kerr, B.A.(2018). Emerging and established models of bone metastasis . Cancers. 10. (6).

Ren, Xiang and Foster, Brittni M. and Ghassemi, Parham and Strobl, Jeannine S. and Kerr, Bethany A. and Agah, Masoud(2018). Entrapment of Prostate Cancer Circulating Tumor Cells with a Sequential Size-Based Microfluidic Chip . Analytical Chemistry. 90. (12). p. 7526-7534.

Foster, B.M., Zaidi, D., Young, T.R., Mobley, M.E., Kerr, B.A.(2018). CD117/c-kit in cancer stem cell-mediated progression and therapeutic resistance . Biomedicines. 6. (1).

Ren, X., Foster, B.M., Ghassemi, P., Strobl, J.S., Kerr, B.A., Agah, M.(2018). Entrapment of Prostate Cancer Circulating Tumor Cells with a Sequential Size-Based Microfluidic Chip . Analytical Chemistry. 90. (12). p. 7526-7534.

Bethany A. Kerr, Koran S. Harris (2017). Prostate Cancer Stem Cell Markers Drive Progression, Therapeutic Resistance, and Bone Metastasis . Stem Cells International.

Harris, K.S., Kerr, B.A.(2017). Prostate Cancer Stem Cell Markers Drive Progression, Therapeutic Resistance, and Bone Metastasis . Stem Cells International. 2017.

Bethany A. Kerr, Xiaoxia Z. West, Young-Woong Kim, Yongzhong Zhao, Miroslava Tischenko, Rebecca M. Cull, Timothy W. Phares, Xiao-Ding Peng, Jeremiah Bernier-Latmani, Tatiana V. Petrova, et al.(2016). Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium . Nature Communications. 7. (1). Springer Science and Business Media {LLC}

Kerr, B.A., West, X.Z., Kim, Y.-W., Zhao, Y., Tischenko, M., Cull, R.M., Phares, T.W., Peng, X.-D., Bernier-Latmani, J., Petrova, T.V., et al.(2016). Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium . Nature Communications. 7.

Bethany Kerr(2015). Abstract 2229: CD117 expression and activation in prostate cancer progression . Cancer Research. 75. (15 Supplement). p. 2229--2229. American Association for Cancer Research ({AACR})

Kerr, Bethany A., Miocinovic, Ranko, Smith, Armine K., West, Xiaoxia Z., Watts, Katherine E., Alzayed, Amanda W., Klink, Joseph C., Mir, Maria C., Sturey, Tiffany, Hansel, Donna E., et al.(2015). CD117(+) cells in the circulation are predictive of advanced prostate cancer . Oncotarget. 6. (3). p. 1889-1897.

Kerr, Bethany A., Miocinovic, Ranko, Smith, Armine K., West, Xiaoxia Z., Watts, Katherine E., Alzayed, Amanda W., Klink, Joseph C., Mir, Maria C., Sturey, Tiffany, Hansel, Donna E., et al.(2015). CD117(+) cells in the circulation are predictive of advanced prostate cancer . Oncotarget. 6. (3). p. 1889-1897.

Kerr, B.A., Miocinovic, R., Smith, A.K., West, X.Z., Watts, K.E., Alzayed, A.W., Klink, J.C., Mir, M.C., Sturey, T., Hansel, D.E., et al.(2015). CD117⁺ cells in the circulation are predictive of advanced prostate cancer . Oncotarget. 6. (3). p. 1889-1897.

Ma, L., Kerr, B.A., Prasad, S.V.N., Byzova, T.V., Somanath, P.R.(2014). Differential effects of Akt1 signaling on short-versus long-term consequences of myocardial infarction and reperfusion injury . Laboratory Investigation. 94. (10). p. 1083-1091.

Kerr, Bethany A., Ma, Lining, Prasad, Sathyamangla V. Naga, Byzova, Tatiana V., Somanath, Payaningal R.(2014). Differential effects of Akt1 signaling on short- versus long-term consequences of myocardial infarction and reperfusion injury . Laboratory Investigation. 94. (10). p. 1083-1091.

Kerr, B.A., Ma, L., West, X.Z., Ding, L., Malinin, N.L., Weber, M.E., Tischenko, M., Goc, A., Somanath, P.R., Penn, M.S., et al.(2013). Interference with akt signaling protects against myocardial infarction and death by limiting the consequences of oxidative stress . Science Signaling. 6. (287).

Kerr, Bethany A., Ma, Lining, West, Xiaoxia Z., Ding, Liang, Malinin, Nikolay L., Weber, Malory E., Tischenko, Mira, Goc, Anna, Somanath, Payaningal R., Penn, Marc S., et al.(2013). Interference with Akt Signaling Protects Against Myocardial Infarction and Death by Limiting the Consequences of Oxidative Stress . Science Signaling. 6. (287).

Kerr, Bethany A., Byzoya, Tatiana V.(2013). Platelet Sequestered Proteins Mediate Pre-Metastatic Communication Between Tumors and Bone . Blood. 122. (21).

Kerr, Bethany A., Byzova, Tatiana V., Feng, Weiyi, McCabe, Patrick(2013). Platelets and the Tumor Cell Microenvironment . Blood. 122. (21).

Kerr, B. A., McCabe, N. P., Feng, W., Byzova, T. V.(2013). Platelets govern pre-metastatic tumor communication to bone . Oncogene. 32. (36). p. 4319-4324.

Kerr, B.A., Mccabe, N.P., Feng, W., Byzova, T.V.(2013). Platelets govern pre-metastatic tumor communication to bone . Oncogene. 32. (36). p. 4319-4324.

Meller, J., Malinin, N. L., Panigrahi, S., Kerr, B. A., Patil, A., Ma, Y., Venkateswaran, L., Rogozin, I. B., Mohandas, N., Ehlayel, M. S., et al.(2012). Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III . Journal of Thrombosis and Haemostasis. 10. (7). p. 1397-1408.

Meller, J., Malinin, N.L., Panigrahi, S., Kerr, B.A., Patil, A., Ma, Y., Venkateswaran, L., Rogozin, I.B., Mohandas, N., Ehlayel, M.S., et al.(2012). Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III . Journal of Thrombosis and Haemostasis. 10. (7). p. 1397-1408.

Kerr, Bethany A., Ma, Lining, West, Xiaoxia Z., Malinin, Nikolay L., Weber, Malory E., Ding, Liang, Somanath, Payaningal R., Podrez, Eugene A., Byzova, Tatiana V.(2012). INTERFERENCE WITH AKT SIGNALLING IN DYSLIPIDEMIA DIMINISHES MYOCARDIAL INFARCTION AND PROMOTES SURVIVAL BY INHIBITING OXIDATIVE STRESS . Heart. 98. p. E7-E8.

Kerr, B.A., Byzova, T.V.(2012). The dark side of the oxidative force in angiogenesis . Nature Medicine. 18. (8). p. 1184-1185.

Kerr, Bethany A., Ma, Lining, West, Xiaoxia Z., Malinin, Nikolay L., Weber, Malory E., Ding, Liang, Somanath, Payaningal R., Podrez, Eugene A., Byzova, Tatiana V.(2012). INTERFERENCE WITH AKT SIGNALLING IN DYSLIPIDEMIA DIMINISHES MYOCARDIAL INFARCTION AND PROMOTES SURVIVAL BY INHIBITING OXIDATIVE STRESS . Heart. 98. p. E7-E8.

Kerr, Bethany A., West, Xiaoxia Z., Meller, Nahum, Malinin, Nikolay L., Deshmukh, Lalit, Meller, Julia, Mahabeleshwar, Ganapati H., Weber, Malory E., Vinogradova, Olga, Byzova, Tatiana V.(2012). Integrin beta(3) Crosstalk with VEGFR Accommodating Tyrosine Phosphorylation as a Regulatory Switch . Plos One. 7. (2).

Kerr, Bethany A., Ma, Lining, West, Xiaoxia Z., Malinin, Nikolay L., Weber, Malory E., Ding, Liang, Somanath, Payaningal R., Penn, Marc S., Podrez, Eugene A., Byzova, Tatiana V.(2012). INTERFERENCE WITH AKT SIGNALING IN DYSLIPIDEMIA DIMINISHES MYOCARDIAL INFARCTION AND PROMOTES SURVIVAL BY INHIBITING OXIDATIVE STRESS . Heart. 98. p. E62-E63.

West, X.Z., Meller, N., Malinin, N.L., Deshmukh, L., Meller, J., Mahabeleshwar, G.H., Weber, M.E., Kerr, B.A., Vinogradova, O., Byzova, T.V.(2012). Integrin β <inf>3</inf> crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch . PLoS ONE. 7. (2).

Kerr, Bethany A., Byzova, Tatiana V.(2012). The dark side of the oxidative force in angiogenesis . Nature Medicine. 18. (8). p. 1184-+.

Feng, W., Madajka, M., Kerr, B.A., Mahabeleshwar, G.H., Whiteheart, S.W., Byzova, T.V.(2011). A novel role for platelet secretion in angiogenesis: Mediating bone marrow-derived cell mobilization and homing (Blood (2011) 117, 14, (3893-3902)) . Blood. 117. (26). p. 7187.

McCabe, N.P., Kerr, B.A., Madajka, M., Vasanji, A., Byzova, T.V.(2011). Augmented osteolysis in SPARC-deficient mice with bone residing prostate cancer . Neoplasia. 13. (1). p. 31-39.

Kerr, B. A., Feng, W., Madajka, M., McCabe, N. P., Byzova, T., V(2011). Platelets transport the tumor secretome during cancer progression and metastasis . Journal of Thrombosis and Haemostasis. 9. p. 242-243.

Feng, W., Madajka, M., Kerr, B.A., Mahabeleshwar, G.H., Whiteheart, S.W., Byzova, T.V.(2011). A novel role for platelet secretion in angiogenesis: Mediating bone marrow-derived cell mobilization and homing (Blood (2011) 117, 14, (3893-3902)) . Blood. 117. (26). p. 7187.

Kerr, Bethany A., McCabe, N. Patrick, Madajka, Maria, Vasanji, Amit, Byzova, Tatiana V.(2011). Augmented Osteolysis in SPARC-Deficient Mice with Bone-Residing Prostate Cancer . Neoplasia. 13. (1). p. 31-U46.

Kerr, Bethany A., Feng, Weiyi, Madajka, Maria, Mahabeleshwar, Ganapati H., Whiteheart, Sidney W., Byzova, Tatiana V.(2011). A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing . Blood. 117. (14). p. 3893-3902.

Feng, W., Madajka, M., Kerr, B.A., Mahabeleshwar, G.H., Whiteheart, S.W., Byzova, T.V.(2011). Anovel role for platelet secretion in angiogenesis: Mediating bone marrow-derived cell mobilization and homing . Blood. 117. (14). p. 3893-3902.

Bethany Kerr, Tatiana Byzova(2010). Integrin alpha V . AfCS-Nature Molecule Pages. Springer Nature

Armine Smith, Bethany Kerr, Eric Klein, Warren Heston, Tatiana Byzova(2010). 695 ROLE OF CIRCULATING NEOPLASTIC PROGENITOR CELLS IN DETECTION AND STAGING OF PROSTATE CANCER . The Journal of Urology. 183. (4). p. e271. Elsevier {BV}

Kerr, Bethany A., Miocinovic, Ranko, Smith, Armine K., Klein, Eric A., Byzova, Tatiana V.(2010). Comparison of Tumor and Microenvironment Secretomes in Plasma and in Platelets during Prostate Cancer Growth in a Xenograft Model . Neoplasia. 12. (5). p. 388-U4.

Kerr, B. A., Byzova, T. V.(2010). Prostate cancer-derived G-CSF primes the pre-metastatic niche . Bone. 47. p. S287-S288.

West, X.Z., Malinin, N.L., Merkulova, A.A., Tischenko, M., Kerr, B.A., Borden, E.C., Podrez, E.A., Salomon, R.G., Byzova, T.V.(2010). Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands . Nature. 467. (7318). p. 972-976.

Kerr, Bethany A., Byzova, Tatiana V.(2010). alpha B-crystallin: a novel VEGF chaperone . Blood. 115. (16). p. 3181-3183.

Kerr, B.A., Miocinovic, R., Smith, A.K., Klein, E.A., Byzova, T.V.(2010). Comparison of tumor and microenvironment secretomes in plasma and in platelets during prostate cancer growth in a xenograft model . Neoplasia. 12. (5). p. 388-396.

Kerr, B.A., Byzova, T.V.(2010). αB-crystallin: A novel VEGF chaperone . Blood. 115. (16). p. 3181-3183.

Kerr, B.A., Byzova, T.V.(2010). αB-crystallin: A novel VEGF chaperone . Blood. 115. (16). p. 3181-3183.

Kerr, Bethany A., West, Xiaoxia Z., Malinin, Nikolay L., Merkulova, Alona A., Tischenko, Mira, Borden, Ernest C., Podrez, Eugene A., Salomon, Robert G., Byzova, Tatiana V.(2010). Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands . Nature. 467. (7318). p. 972-U150.

Kerr, Bethany A., Otani, Tomohiro, Koyama, Eiki, Freeman, Theresa A., Enomoto-Iwamoto, Motomi(2008). Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes . Experimental Cell Research. 314. (6). p. 1301-1312.

Kerr, B.A., Otani, T., Koyama, E., Freeman, T.A., Enomoto-Iwamoto, M.(2008). Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes . Experimental Cell Research. 314. (6). p. 1301-1312.

Szymczyk, K.H., Kerr, B.A.E., Freeman, T.A., Adams, C.S., Steinbeck, M.J.(2006). Involvement of hydrogen peroxide in the differentiation and apoptosis of preosteoclastic cells exposed to arsenite . Biochemical Pharmacology. 72. (6). p. 761-769.

Szymczyk, K. H., Kerr, B. A. E., Freeman, T. A., Adams, C. S., Steinbeck, M. J.(2006). Involvement of hydrogen peroxide in the differentiation and apoptosis of preosteoclastic cells exposed to arsenite . Biochemical Pharmacology. 72. (6). p. 761-769.

Szymczyk, KH, Kerr, BA, Adams, CS, Steinbeck, MJ(2003). Arsenite induces differentiation and apoptosis of pre-osteoclastic cells by a hydrogen peroxide-dependent mechanism . Journal of Bone and Mineral Research. 18. p. S348.

OTHER

Bethany A. Kerr, Kendall L. Langsten, Lihong Shi, Adam S. Wilson, Brian Westwood, Maria T. Xie, Victoria E. Surratt, JoLyn Turner, Ravi Singh, Katherine L. Cook(2021). A Novel Model of Estrogen Receptor-Positive Breast Cancer Bone Metastasis with Antiestrogen Responsiveness . Cold Spring Harbor Laboratory

Bethany A. Kerr, Koran S. Harris, Lihong Shi, Jeffrey S. Willey, David R. Soto-Pantoja, Tatiana V. Byzova(2020). Platelet TSP-1 Controls Prostate Cancer-Induced Osteoclast Differentiation and Bone Marrow-Derived Cell Mobilization through TGFβ-1 . Cold Spring Harbor Laboratory

Lihong Shi, Alexander H. Jinnah, Jeffrey S. Willey, Donald P. Lennon, Arnold I. Caplan, Tatiana V. Byzova, Bethany A. Kerr(2019). Kindlin-3 Mutation in Mesenchymal Stem Cells Results in Enhanced Chondrogenesis . Cold Spring Harbor Laboratory

Bethany A. Kerr, Daniel N. Bracey, Alexander H. Jinnah, Jeffrey S. Willey, Thorsten M. Seyler, Ian D. Hutchinson, Patrick W. Whitlock, Thomas L. Smith, Kerry A. Danelson, Cynthia L. Emory(2018). Investigating the Osteoinductive Potential of a Decellularized Xenograft Bone Substitute . Cold Spring Harbor Laboratory

Bethany A. Kerr, Alexander H. Jinnah, Benjamin C. Zacks, Chukwuweike Gwam(2018). Emerging and Established Models of Bone Metastasis . {MDPI} {AG}

Koran Harris, Brittni Foster, Lihong Shi, Mary Mobley, Phyllis Elliott, Bethany Kerr(2018). CTC Marker CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance . Cold Spring Harbor Laboratory

Bethany A. Kerr, Brittni M. Foster, Danish Zaidi, Tyler R. Young, Mary E. Mobley(2018). CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance . Cold Spring Harbor Laboratory

Bethany A. Kerr, Tatiana V. Byzova(2018). Integrin Alpha V (ITGAV) . Encyclopedia of Signaling Molecules. p. 2634--2645. Springer International Publishing

WORKING PAPER

Emerging and Established Models of Bone Metastasis .

Emerging and Established Models of Bone Metastasis .