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Hire Arindam S.

India

USD 30 /hr

PhD Cancer Biologist | Expert in Tumor Microenvironment & Cell Signaling | Scientific Consulting & Editing

Profile Summary

As a dedicated Cancer Biologist with a Ph.D. in Biotechnology and recent postdoctoral experience at the Sylvester Comprehensive Cancer Center (University of Miami), I specialize in advanced oncology research, molecular signaling, and the tumor microenvironment. My research career has been intensely focused on unravelling complex oncogenic mechanisms, particularly in the contexts of colorectal cancer and breast cancer brain metastasis. I possess deep, hands-on technical expertise in analyzing critical molecular signaling pathways, including PTP1B, PI3K/Akt/mTOR, and Wnt/β-catenin. Having navigated rigorous, high-impact academic research environments, I now leverage this analytical and laboratory background to provide specialized consulting for biotech startups, independent researchers, and pharmaceutical teams. Core Services I Offer: Scientific Writing & Proofreading: Drafting, editing, and refining high-impact manuscripts, review articles, and scientific abstracts for clarity and journal compliance. Comprehensive Literature Reviews: Conducting systematic deep-dives into targeted oncology, genetics, or molecular biology topics. Grant & Proposal Consulting: Assisting with the scientific narrative and structural formulation of research proposals to maximize funding success. Experimental Design & Data Analysis: Advising on robust methodologies and interpreting complex biological data related to cell signaling and tumor microenvironment assays. I am highly detail-oriented, committed to scientific precision, and dedicated to delivering publication-ready results. Let's collaborate to accelerate your next research or commercial biotech project.

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Cell Biology
• ☆ Cell Signaling Pathways
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ 3D Cell Culture
• ☆ Breast Cancer
• ☆ Oncology
• ☆ Cancer Research
• ☆ Cancer Biology

Services

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Medical Writing, Copywriting

Research User Research, Feasibility Study, Technology Scouting, Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Work Experience

Postdoctoral Associate

University of Miami

March 2025 - November 2025

Junior Research Fellow

Tata Medical Center

2017 - 2018

Education

PhD/CSIR SRF (Department of Biotechnology)

Maulana Abul Kalam Azad University of Technology, West Bengal

June 2019 - August 2029

M.Sc. (Department of Physiology)

University of Calcutta

2014 - 2016

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Arindam Sain, Mahesh D. Vaghasiya, Jigarkumar V. Mendapara, Dipshikha Khamrai, Debdut Naskar, Premlata Kumari (2025). Thiazepine‐Based Hybrids as Promising Anti‐Colon Cancer Agents: Design, Synthesis, Computational and In Vitro Screening . Chemistry & Biodiversity.

Vaghasiya, M.D., Sain, A., Mendapara, J.V., Khamrai, D., Naskar, D., Kumari, P.(2024). Thiazepine-Based Hybrids as Promising Anti-Colon Cancer Agents: Design, Synthesis, Computational and In Vitro Screening . Chemistry and Biodiversity.

Sain, Arindam, Vaghasiya, Mahesh D., Mendapara, Jigarkumar V., Khamrai, Dipshikha, Naskar, Debdut, Kumari, Premlata (2024). Thiazepine-Based Hybrids as Promising Anti-Colon Cancer Agents: Design, Synthesis, Computational and <i>In Vitro</i> Screening . Chemistry and Biodiversity.

Arindam Sain, Dipshikha Khamrai, Thirukumaran Kandasamy, Debdut Naskar (2023). Apigenin exerts anti-cancer effects in colon cancer by targeting HSP90AA1 . Journal of Biomolecular Structure and Dynamics.

Sain, A., Kandasamy, T., Naskar, D.(2023). Targeting UNC-51-like kinase 1 and 2 by lignans to modulate autophagy: possible implications in metastatic colorectal cancer . Molecular Diversity. 27. (1). p. 27-43.

Sain, Arindam, Khamrai, Dipshikha, Kandasamy, Thirukumaran, Naskar, Debdut (2023). Apigenin exerts anti-cancer effects in colon cancer possibly by regulating Heat shock protein 90 alpha family class A member 1 (HSP90AA1) . BioRxiv.

Sain, A., Khamrai, D., Kandasamy, T., Naskar, D.(2023). Apigenin exerts anti-cancer effects in colon cancer by targeting HSP90AA1 . Journal of Biomolecular Structure and Dynamics.

Arindam Sain, Dipshikha Khamrai, Thirukumaran Kandasamy, Debdut Naskar (2022). Targeting protein tyrosine phosphatase 1B in obesity‐associated colon cancer: Possible role of sweet potato (Ipomoea batatas) . Proteins: Structure, Function, and Bioinformatics.

Arindam Sain and Dipshikha Khamrai and Thirukumaran Kandasamy and Debdut Naskar(2022). Targeting Protein Tyrosine Phosphatase 1B in Obesity‐associated Colon Cancer: Possible Role of Sweet Potato ( Ipomoea batatas ) . Proteins: Structure, Function, and Bioinformatics. Wiley

Sain, A., Sahu, S., Naskar, D.(2022). Potential of olive oil and its phenolic compounds as therapeutic intervention against colorectal cancer: A comprehensive review . British Journal of Nutrition. 128. (7). p. 1257-1273.

Sain, Arindam, Sahu, Sakshi, Naskar, Debdut (2022). Potential of olive oil and its phenolic compounds as therapeutic intervention against colorectal cancer: a comprehensive review . British Journal of Nutrition.

Sain, A., Kandasamy, T., Naskar, D.(2022). In silico approach to target PI3K/Akt/mTOR axis by selected Olea europaea phenols in PIK3CA mutant colorectal cancer . Journal of Biomolecular Structure and Dynamics. 40. (21). p. 10962-10977.

Sain, Arindam, Kandasamy, Thirukumaran, Naskar, Debdut (2022). In silico approach to target PI3K/Akt/mTOR axis by selected Olea europaea phenols in PIK3CA mutant colorectal cancer . Journal of Biomolecular Structure and Dynamics.

Sain, A., Khamrai, D., Kandasamy, T., Naskar, D.(2022). Targeting protein tyrosine phosphatase 1B in obesity-associated colon cancer: Possible role of sweet potato (Ipomoea batatas) . Proteins: Structure, Function and Bioinformatics. 90. (6). p. 1346-1362.

Sain, Arindam, Khamrai, Dipshikha, Kandasamy, Thirukumaran, Naskar, Debdut (2022). Targeting protein tyrosine phosphatase 1B in obesity-associated colon cancer: Possible role of sweet potato (Ipomoea batatas) . Proteins: Structure, Function, and Bioinformatics.

Sain, Arindam, Kandasamy, Thirukumaran, Naskar, Debdut (2022). Targeting UNC-51-like kinase 1 and 2 by lignans to modulate autophagy: possible implications in metastatic colorectal cancer . Molecular Diversity.

Arindam Sain and Sakshi Sahu and Debdut Naskar(2021). Potential of olive oil and its phenolic compounds as therapeutic intervention against colorectal cancer: a comprehensive review . British Journal of Nutrition. p. 1--17. Cambridge University Press ({CUP})

Arindam Sain and Thirukumaran Kandasamy and Debdut Naskar(2021). In silico approach to target PI3K/Akt/mTOR axis by selected Olea europaea phenols in PIK3CA mutant colorectal cancer . Journal of Biomolecular Structure and Dynamics. p. 1--16. Informa {UK} Limited

Sayan Ghosh and Sreetama Choudhury and Olivia Chowdhury and Sudeshna Mukherjee and Ankur Das and Arindam Sain and Payal Gupta and Arghya Adhikary and Sreya Chattopadhyay(2020). Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine . Cellular Signalling. 68. p. 109521. Elsevier {BV}

Ghosh, S., Choudhury, S., Chowdhury, O., Mukherjee, S., Das, A., Sain, A., Gupta, P., Adhikary, A., Chattopadhyay, S.(2020). Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine . Cellular Signalling. 68.

Ghosh, Sayan, Choudhury, Sreetama, Chowdhury, Olivia, Mukherjee, Sudeshna, Das, Ankur, Gupta, Payal, Adhikary, Arghya, Chattopadhyay, Sreya, Sain, Arindam (2020). Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine . Cellular Signalling.

Payal Gupta and Sreetama Choudhury and Sayan Ghosh and Sudeshna Mukherjee and Olivia Chowdhury and Arindam Sain and Sreya Chattopadhyay(2019). Dietary pomegranate supplement alleviates murine pancreatitis by modulating Nrf2-p21 interaction and controlling apoptosis to survival switch . The Journal of Nutritional Biochemistry. 66. p. 17--28. Elsevier {BV}

Gupta, P., Choudhury, S., Ghosh, S., Mukherjee, S., Chowdhury, O., Sain, A., Chattopadhyay, S.(2019). Dietary pomegranate supplement alleviates murine pancreatitis by modulating Nrf2-p21 interaction and controlling apoptosis to survival switch . Journal of Nutritional Biochemistry. 66. p. 17-28.

Sain, Arindam, Gupta, Payal, Choudhury, Sreetama, Ghosh, Sayan, Mukherjee, Sudeshna, Chowdhury, Olivia, Chattopadhyay, Sreya (2019). Dietary pomegranate supplement alleviates murine pancreatitis by modulating Nrf2-p21 interaction and controlling apoptosis to survival switch . The Journal of Nutritional Biochemistry.

OTHER

Sain, A., Barman, S., Khamrai, D., Srinivas, M., Singh, P., Simpi, B., Varshney, M., Naskar, D.(2024). Olive phenolic compounds, potent tankyrase 1 inhibitor exhibit anti colon cancer effects by blocking Wnt/β-catenin pathway . bioRxiv.

Sain, A., Khamrai, D., Kandasamy, T., Naskar, D.(2023). Apigenin exerts anti-cancer effects in colon cancer possibly by regulating Heat shock protein 90 alpha family class A member 1 (HSP90AA1) . bioRxiv.

PREPRINT

Arindam Sain, Debdut Naskar, Dipsikha Khamrai, Thirukumaran Kandasamy(2023). Apigenin exerts anti-cancer effects in colon cancer possibly by regulating Heat shock protein 90 alpha family class A member 1 (HSP90AA1) . Cold Spring Harbor Laboratory

CONFERENCE POSTER

Sain, A., Khamrai, D., Srinivas, M., Varshney, M., & Naskar, D. (2023). Targeting Pro-tumorigenic actions of Tankyrase 1 in Colorectal Cancer: Possible Solution through Olive Phenols .

CONFERENCE ABSTRACT

Arindam Sain, Dipsikha Khamrai, Dipsikha Khamrai, Dipsikha Khamrai, Thirukumaran Kandasamy, Thirukumaran Kandasamy, Thirukumaran Kandasamy, Thirukumaran Kandasamy, Debdut Naskar, Debdut Naskar, et al.(2023). Heat shock protein 90 alpha family class A member 1 (HSP90AA1) Revealed as a Plausible Target of Apigenin in Colon Cancer . Fifth Regional Science and Technology Congress, 2023. Unpublished

(2021). Targeting Protein Tyrosine Phosphatase 1B with Sweet Potato (Ipomoea batatas) derived Compounds in Obesity-linked Colon Cancer. National Annual Biotechnology Symposium - SymBiot’21.

Sain A, Kandasamy T, Naskar D. Exploring the Potential of Apigenin as a Dual PI3K/mTOR Inhibitor to Target PIK3CA Mutant Colorectal Cancer: An In-Silico Analysis 2020.

CONFERENCE PAPER

(2022). Apigenin as phytomedicine in colon cancer: target identification and validation . National Bioengineering Conference 2022 (NBC -2022).