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Hire Andriy A.

United States

USD 70 /hr

PhD Biophysicist expert in mechanosensation, MD simulations, structural biology, and data-driven model validation.

Profile Summary

Professional Overview I am doctoral-level Associate Research Scientist specializing in mechanosensitive ion channels, computational biophysics, structural biology, biochemical kinetics, and data integrity validation. With nearly three decades of experience operating within top-tier United States academic institutions, my career has been dedicated to modeling, simulating, and validating the behavior of complex biological systems. I provide expert scientific consulting, mathematical modeling, and pre-submission peer-review auditing for biotechnology startups, R&D labs, and academic research groups. Research Specialization & Projects My primary research focus lies at the intersection of membrane biophysics, structural biology, and cellular kinetics. I specialize in the structural and kinetic mechanisms of membrane proteins, with specific, long-term expertise in mechanosensitive ion channels (including MscS and MscL) and protein-lipid interactions. My ongoing and recent research initiatives include: * Bacterial Osmotic Fitness: Developing mathematical and computational frameworks to analyze global and local forces governing bacterial hypoosmotic responses. * Channel Kinetics & Inactivation: Investigating the voltage-dependent processes, lipid-mediated mechanisms, and phosphorylation behaviors that regulate channel activation and inactivation. * Precision Nutrition Modeling: Utilizing advanced computational methods to unravel complex protein-metabolite interactions. Technical Expertise & Methodologies I bring a highly analytical, data-driven mindset to complex troubleshooting and system configuration. My core technical capabilities include: * Biomolecular Simulations: Advanced molecular dynamics (MD) simulations, structural refinement, and protein-lipid system setup. * Computational Toolkit: Expert-level proficiency in NAMD, VMD, Tcl scripting, MATLAB, CHARMM-GUI, COPASI, and Slurm for high-performance computing (HPC) workflows. * Data Analytics & Modeling: Mathematical modeling of biological systems, chemical physics analysis, biological thermodynamics, and kinetic data evaluation. Academic Track Record & Consulting Capabilities I have a deep commitment to scientific rigor and data integrity, backed by more than 80 co-authored papers in high-impact, peer-reviewed journals (including PNAS, Journal of Biological Chemistry, Biophysical Journal, and iScience). On Kolabtree, I offer specialized consulting services in: * Experimental & Simulation Design: Auditing and troubleshooting molecular dynamics workflows, simulation parameters, and computational modeling strategies. * Grant & Manuscript Peer Review: Conducting rigorous pre-submission scientific reviews of manuscripts and grant proposals to ensure methodological soundness, logical flow, and data integrity. * Kinetic Data Evaluation: Helping research teams translate raw biophysical and kinetic data into predictive, structurally sound mathematical models. * Molecular data visualization

Subject Matter Expertise

• ☆ Biostatistics
• ☆ Mathematical Biology
• ☆ Biochemistry
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Molecular Evolution
• ☆ Cell Biology
• ☆ Membrane Biology
• ☆ Biophysics
• ☆ Biotechnology & Bioengineering
• ☆ Biomechanics
• ☆ Data Collection
• ☆ Statistical Mechanics
• ☆ Thermodynamics
• ☆ Cell Surface Receptors
• ☆ Biosensors
• ☆ Cytometry
• ☆ Information & Knowledge Management
• ☆ Matlab
• ☆ Excel
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Language Translation
• ☆ Speechwriting
• ☆ Course Content Writing
• ☆ Grant Writing

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Medical Writing, Technical Writing, Copywriting

Research Fact Checking, Scientific and Technical Research

Consulting Digital Strategy Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics

Work Experience

Associate Research Scientist

University of Maryland Medical Center

August 2021 - Present

Associate Research Scientist

University of Maryland, College Park

July 2021 - Present

Education

Ph. D. (Candidate of Sciences) (Molecular and Applied Biophysics)

Kharkiv National University

June 1994 - June 1999

M.Sc. in Biophysics

Kharkiv National University, Kharkiv, Ukraine

September 1989 - June 1994

High school

School 51, Kharkiv, Ukraine

September 1979 - May 1989

Certifications

• PhD in Biophysics

  Biology Research Institute of Kharkiv National University, Kharkiv, Ukraine

  July 1999 - Present

• M.Sc. in Biophysics, 1st Class Honors Degree

  Kharkiv National University, Kharkiv, Ukraine

  June 1994 - Present

Publications

JOURNAL ARTICLE

Anishkin, Andriy, Parthasarathy, Aravind, Xie, Yangjing, Drachuk, Kostiantyn, Nishijma, Yoshinori, Fang, Juan, Koukouritaki, Sevasti B, Wilcox, David A, Zhang, David X(2025). Phosphorylation of distal C-terminal residues promotes TRPV4 channel activation in response to arachidonic acid. Journal of Biological Chemistry. 301. (3). Elsevier

Anishkin, Andriy, Chintapalli, Sree, Adepu, Kiran Kumar, Adams, Sean(2025). Abstract 1547 Innovative Insights into Myoglobin-Metabolite Interactions and Muscle Cell Bioenergetics. Journal of Biological Chemistry. 301. (5). Elsevier

Andriy Anishkin, Kiran Kumar Adepu, Sean H. Adams, Sree V. Chintapalli (2024). A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin . Physiological Reviews.

Anishkin, Andriy, Adepu, Kiran Kumar, Adams, Sean H, Chintapalli, Sree V(2024). A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin . Physiological Reviews. 104. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1611--1642. American Physiological Society Rockville, MD

Anishkin, Andriy, Britt, Madolyn, Moller, Elissa, Maramba, Joseph, Sukharev, Sergei(2024). Asymmetric interfacial anchors reveal principles of gating and metabolic control of the bacterial mechanosensitive channel MscS. Biophysical Journal. 123. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 469a. Elsevier

Anishkin, Andriy, Moller, Elissa, Britt, Madolyn, Yoshimura, Kenjiro, Zhou, Fei, Matthies, Doreen, Sukharev, Sergei(2024). In search of a compact closed conformation of bacterial mechanosensitive channel MscS. Biophysical Journal. 123. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 211a--212a. Elsevier

Anishkin, Andriy, Chintapalli, Sree V, Adepu, KiranKumar, Bhandari, Dipendra, Adams, Sean H(2024). Molecular insights into myoglobin binding patterns with the outer mitochondrial membrane: A comparison of oxygenated and deoxygenated states. Biophysical Journal. 123. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 68a. Elsevier

Anishkin, Andriy, Britt, Madolyn, Moller, Elissa, Maramba, Joseph, Sukharev, Sergei(2024). MscS inactivation and recovery are slow voltage-dependent processes sensitive to interactions with lipids. Biophysical Journal. 123. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 195--209. Elsevier

Anishkin, Andriy, Chintapalli, Sree Vamsee, Adepu, Kiran Kumar, Baumbauer, Kyle, Bhandari, Dipendra, Gosh, Anuradha, Kay, Colin, Young, Erin(2024). Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery. Current Developments in Nutrition. 8. Elsevier

Anishkin, Andriy, Ramsey, Kristen, Britt, Madolyn, Maramba, Joseph, Ushijima, Blake, Moller, Elissa, Häse, Claudia, Sukharev, Sergei(2024). The dynamic hypoosmotic response of Vibrio cholerae relies on the mechanosensitive channel MscS. Iscience. 27. (6). Elsevier

Anishkin, Andriy, Bhandari, Dipendra, Adepu, Kiran Kumar, Kay, Colin D, Young, Erin E, Baumbauer, Kyle M, Ghosh, Anuradha, Chintapalli, Sree V(2024). Unraveling protein-metabolite interactions in precision nutrition: a case study of blueberry-derived metabolites using advanced computational methods. Metabolites. 14. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 430. MDPI

Andriy Anishkin, Elissa Moller, Madolyn Britt, Anthony Schams, Hannah Cetuk, Sergei Sukharev (2023). Mechanosensitive channel MscS is critical for termination of the bacterial hypoosmotic permeability response . Journal of General Physiology.

Anishkin, Andriy, Moller, Elissa, Britt, Madolyn, Matthies, Doreen, Sukharev, Sergei(2023). A search for the resting conformation of the bacterial mechanosensitive channel MSCs. Biophysical Journal. 122. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 160a--161a. Elsevier

Anishkin, Andriy, Adepu, Kiran Kumar, Bhandari, Dipendra, Adams, Sean H, Chintapalli, Sree V(2023). Computational analysis reveals unique binding patterns of oxygenated and deoxygenated myoglobin to the outer mitochondrial membrane. Biomolecules. 13. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1138. MDPI

Sukharev, S, Anishkin, A(2023). Mechanosensitive Channels: History, Diversity, and Emerging Mechanisms. Biologičeskie membrany. 40. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 19--42.

Anishkin, Andriy, Britt, Madolyn, Moller, Elissa, Sukharev, Sergei I(2023). The role of protein-membrane electrostatic interactions in the adaptive gating cycle of MscS. Biophysical Journal. 122. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 89a. Elsevier

Anishkin, Andriy, Sharma, Arjun, Sukharev, Sergei, Vanegas, Juan M(2023). Tight hydrophobic core and flexible helices yield MscL with a high tension gating threshold and a membrane area mechanical strain buffer. Frontiers in Chemistry. 11. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1159032. Frontiers Media SA

Anishkin, Andriy, Moller, Elissa, Britt, Madolyn, Schams, Anthony, Cetuk, Hannah, Sukharev, Sergei(2023). Mechanosensitive channel MscS is critical for termination of the bacterial hypoosmotic permeability response . Journal of General Physiology. 155. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e202213168. Rockefeller University Press

Anishkin, Andriy, Adepu, Kiran Kumar, Kachhap, Sangita, Bhandari, Dipendra, Chintapalli, Sree V(2022). Computational insights on molecular interactions of acifran with GPR109A and GPR109B. Journal of Molecular Modeling. 28. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 237. Springer Berlin Heidelberg Berlin/Heidelberg

Anishkin, Andriy, Bhandari, Dipendra, Kachhap, Sangita, Madhukar, Geet, Adepu, Kiran Kumar, Chen, Jin-Ran, Chintapalli, Sree V(2022). Exploring GPR109A receptor interaction with hippuric acid using MD simulations and CD spectroscopy. International Journal of Molecular Sciences. 23. (23). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 14778. MDPI

Sukharev, S, Anishkin, A(2022). Mechanosensitive channels: History, diversity, and mechanisms. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 16. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 291--310. Pleiades Publishing Moscow

Anishkin, Andriy, Adepu, Kiran Kumar, Bhandari, Dipendra, Adams, Sean H, Chintapalli, Sree V(2022). Myoglobin interaction with lactate rapidly releases oxygen: studies on binding thermodynamics, spectroscopy, and oxygen kinetics. International Journal of Molecular Sciences. 23. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4747. MDPI

Anishkin, Andriy, Adepu, Kiran Kumar, Bhandari, Dipendra, Adams, Sean H, Chintapalli, Sree V(2022). Myoglobin--Pyruvate Interactions: Binding Thermodynamics, Structure--Function Relationships, and Impact on Oxygen Release Kinetics. International journal of molecular sciences. 23. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8766. MDPI

Anishkin, Andriy, Britt, Madolyn, Yoshimura, Kenjiro, Moller, Elissa, Sukharev, Sergei I(2022). The role of electrostatic interactions in the stabilization of main functional states of the bacterial mechanosensitive channel MscS. Biophysical Journal. 121. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 461a. Elsevier

Anishkin, Andriy, Moller, Elissa, Britt, Madolyn, Kumar, Praveen, Kane, Maureen A, Sukharev, Sergei I(2022). The selectivity of the bacterial mechanosensitive channel MscS is tuned to support fast electroneutral osmolyte transport. Biophysical Journal. 121. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 491a. Elsevier

Anishkin, Andriy, Dave, Noopur, Cetiner, Ugur, Arroyo, Daniel, Fonbuena, Joshua, Tiwari, Megna, Barrera, Patricia, Lander, Noelia, Sukharev, Sergei, Jimenez, Veronica(2021). A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi. elife. 10. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e67449. eLife Sciences Publications, Ltd

Anishkin, Andriy, Cetuk, Hannah, Scott, Alison J, Rempe, Susan B, Ernst, Robert K, Sukharev, Sergei(2021). Partitioning of seven different classes of antibiotics into LPS monolayers supports three different permeation mechanisms through the outer bacterial membrane. Langmuir. 37. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1372--1385. American Chemical Society

Anishkin, Andriy, Adepu, Kiran Kumar, Kachhap, Sangita, Chintapalli, Sree V(2021). Structural and energetic insights into the interaction of niacin with the GPR109A receptor. Bioinformatics and biology insights. 15. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11779322211056122. SAGE Publications Sage UK: London, England

Anishkin, Andriy, Maramba, Joseph, Moller, Elissa, Britt, Madolyn, Sukharev, Sergei I(2021). The Interfacial Electrostatics Defines MscS Gating and Inactivation. Biophysical Journal. 120. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 234a. Elsevier

Anishkin, Andriy, Sukharev, Sergei, Vanegas, Juan M, others(2021). Mechanical activation of MscL revealed by a locally distributed tension molecular dynamics approach . Biophysical journal. 120. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 232--242. Elsevier

Tatikonda, RR, Anishkin, A, Sukharev, S, Vanegas, JM(2020). Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach . bioRxiv. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2020--08. Cold Spring Harbor Laboratory

Anishkin, Andriy, Amirshenava, Marzie, Mishra, Aditi, Sukharev, Sergei I, Milescu, Mirela, Milescu, Lorin S(2020). A Model-Driven Analysis of Thermosensation Mechanisms in the Family of Ionotropic Gustatory Receptors from Drosophila Genus. Biophysical Journal. 118. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 276a. Elsevier

Anishkin, Andriy, Jegla, Timothy J, Zhou, Yunqing, Pisupati, Aditya, Simonson, Benjamin T, King, Kathryn, van Rossum, Damian B(2020). Extracellular HEME Modulates Voltage-gating in CNBD Superfamily Cation Channels. Biophysical Journal. 118. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 111a. Elsevier

Anishkin, Andriy, Britt, Madolyn, Ramsey, Kristen, Maramba, Joseph, Ushijima, Blake, Moller, Elissa, Hase, Claudia, Sukharev, Sergei I(2020). MSCS is a Critical Component for Osmotic Survival of Vibrio Cholerae. Biophysical Journal. 118. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 251a. Elsevier

Anishkin, Andriy, Lubkowski, Jacek, Vanegas, Juan, Chan, Wai-Kin, Lorenzi, Philip L, Weinstein, John N, Sukharev, Sergei, Fushman, David, Rempe, Susan, Wlodawer, Alexander(2020). Mechanism of Catalysis by l-Asparaginase. Biochemistry. 59. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1927--1945. American Chemical Society

Anishkin, Andriy, Pudrovska, Tetyana(2020). Personal mastery and the medical, financial, and physical cancer burden: gender and race differences among older adults. Journal of Aging and Health. 32. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1233--1243. Sage Publications Sage CA: Los Angeles, CA

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2019). Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia . Molecular Cancer Therapeutics.

Anishkin, Andriy, Chan, Wai-Kin, Horvath, Thomas D, Tan, Lin, Link, Todd, Harutyunyan, Karine G, Pontikos, Michael A, Du, Di, Martin, Leona A, Yin, Eric, et al.(2019). Glutaminase activity of L-asparaginase contributes to durable preclinical activity against acute lymphoblastic leukemia . Molecular cancer therapeutics. 18. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1587--1592. American Association for Cancer Research

Anishkin, Andriy, Teng, Jinfeng, Kung, Ching, Blount, Paul(2019). Human mutations highlight an intersubunit cation--$π$ bond that stabilizes the closed but not open or inactivated states of TRPV channels. Proceedings of the National Academy of Sciences. 116. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9410--9416. National Academy of Sciences

Anishkin, Andriy, Najem, Joseph S, Rowe, Ian, Maramba, Joseph, Leo, Donald J, Sukharev, Sergei(2019). Voltage Dependence and Modulation of Bacterial Channel MscL. Biophysical Journal. 116. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 377a. Elsevier

Andriy Anishkin, Aditya Pisupati, Keith J. Mickolajczyk, William Horton, Damian B. van Rossum, Sree V. Chintapalli, Xiaofan Li, Jose Chu-Luo, Gregory Busey, William O. Hancock, et al.(2018). The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry . Journal of General Physiology. 150. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1702--1721. Rockefeller University Press

Anishkin, Andriy, Pisupati, Aditya, Mickolajczyk, Keith J, Horton, William, van Rossum, Damian B, Chintapalli, Sree V, Li, Xiaofan, Chu-Luo, Jose, Busey, Gregory, Hancock, William O, et al.(2018). The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry . Journal of General Physiology. 150. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1702--1721. Rockefeller University Press

Anishkin, Andriy, Dave, Noopur, Cetiner, Ugur, Daniel, Arroyo, Fonbuena, Joshua, Barrera, Patricia, Lander, Noelia, Sukharev, Sergei, Jimenez, Veronica(2018). A bacterial-like mechanosensitive channel controls osmoregulation and infectivity in Trypanosoma cruzi. bioRxiv. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 498469. Cold Spring Harbor Laboratory

Anishkin, Andriy, Chintapalli, Sree V, Adams, Sean H(2018). Binding energies and the entry route of palmitic acid and palmitoylcarnitine into myoglobin. Data in brief. 21. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1106--1110. Elsevier

Anishkin, Andriy, Lubkowski, Jacek, Sonmez, Cem, Smirnov, Sergey V, Kotenko, Sergei V, Wlodawer, Alexander(2018). Crystal structure of the labile complex of IL-24 with the extracellular domains of IL-22R1 and IL-20R2. The Journal of Immunology. 201. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2082--2093. Oxford University Press

Anishkin, Andriy, Schams, Anthony, Britt, Madolyn, Rowe, Ian, Cetiner, Ugur, Sukharev, Sergei(2018). Dissecting the Fast Hypoosmotic Permeability Response in E. coli. Biophysical Journal. 114. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 112a--113a. Elsevier

Anishkin, Andriy, Chintapalli, Sree V, Adams, Sean H(2018). Exploring the entry route of palmitic acid and palmitoylcarnitine into myoglobin. Archives of biochemistry and biophysics. 655. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 56--66. Academic Press

Anishkin, Andriy, Çetiner, Uğur, Sukharev, Sergei(2018). Spatiotemporal relationships defining the adaptive gating of the bacterial mechanosensitive channel MscS. European Biophysics Journal. 47. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 663--677. Springer International Publishing Cham

Anishkin, Andriy, Najem, Joseph S, Rowe, Ian, Leo, Donald J, Sukharev, Sergei(2018). The voltage-dependence of MscL has dipolar and dielectric contributions and is governed by local intramembrane electric field. Scientific reports. 8. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13607. Nature Publishing Group UK London

Anishkin, Andriy, Cao, Sheng, Zinkevich, Natalya S, Nishijima, Yoshinori, Korishettar, Ankush, Wang, Zhihao, Fang, Juan, Wilcox, David A, Zhang, David X(2018). Transient receptor potential vanilloid 4 (TRPV4) activation by arachidonic acid requires protein kinase A--mediated phosphorylation. Journal of Biological Chemistry. 293. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5307--5322. Elsevier

Tension-activated channels in the mechanism of osmotic fitness in Pseudomonas aeruginosa @article{_etiner_2017, doi = {10.1085/jgp.201611699}, url = {https://doi.org/10.1085%2Fjgp.201611699}, year = 2017, month = {apr}, publisher = {Rockefeller University Press}, volume = {149}, number = {5}, pages = {595--609}, author = {U{\u{g}}ur {\c{C}}etiner and Ian Rowe and Anthony Schams and Christina Mayhew and Deanna Rubin and Andriy Anishkin and Sergei Sukharev}, title = {Tension-activated channels in the mechanism of osmotic fitness in Pseudomonas aeruginosa}, journal = {The Journal of General Physiology} } . Journal of General Physiology.

Anishkin, Andriy, Ermakov, Yuri A, Kamaraju, Kishore, Dunina-Barkovskaya, Antonina, Vishnyakova, Khava S, Yegorov, Yegor E, Sukharev, Sergei(2017). High-affinity interactions of beryllium (2+) with phosphatidylserine result in a cross-linking effect reducing surface recognition of the lipid. Biochemistry. 56. (40). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5457--5470. American Chemical Society

Anishkin, Andriy, Çetiner, Uğur, Rowe, Ian, Schams, Anthony, Mayhew, Christina, Rubin, Deanna, Sukharev, Sergei(2017). Tension-activated channels in the mechanism of osmotic fitness in Pseudomonas aeruginosa . Journal of General Physiology. 149. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 595--609. The Rockefeller University Press

Anishkin, Andriy, Cetiner, Ugur, Rowe, Ian, Schams, Anthony, Mayhew, Christina, Rubin, Deanna, Sukharev, Sergei(2017). Cell Population and Electrophysiology Approaches to Osmotic Fitness of Pseudomonas Aeruginosa. Biophysical Journal. 112. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 567a. Elsevier

Anishkin, Andriy, Teng, Jinfeng, Loukin, Stephen H, Blount, Paul, Kung, Ching(2016). A Lipid-Exposed Residue at the Start of S4-S5 Linker Controls TRPV4 Gating. Biophysical Journal. 110. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 286a--287a. Elsevier

Anishkin, Andriy, Teng, Jinfeng, Loukin, Stephen H, Kung, Ching(2016). A competing hydrophobic tug on L596 to the membrane core unlatches S4--S5 linker elbow from TRP helix and allows TRPV4 channel to open. Proceedings of the National Academy of Sciences. 113. (42). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11847--11852. National Academy of Sciences

Anishkin, Andriy, Rowe, Ian, Cetiner, Ugur, Schams, Anthony, Sukharev, Sergei(2016). Fast Osmotic Permeability Responses in Bacteria. Biophysical Journal. 110. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 93a. Elsevier

Anishkin, Andriy, Chintapalli, Sree V, Jayanthi, Srinivas, Mallipeddi, Prema L, Gundampati, Ravikumar, Kumar, Thallapuranam Krishnaswamy Suresh, Van Rossum, Damian B, Adams, Sean H(2016). Novel molecular interactions of acylcarnitines and fatty acids with myoglobin. Journal of Biological Chemistry. 291. (48). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 25133--25143. Elsevier

Anishkin, Andriy, Czerny, Daniel D, Padmanaban, Senthilkumar, Venema, Kees, Riaz, Zoya, Sze, Heven(2016). Protein architecture and core residues in unwound $α$-helices provide insights to the transport function of plant AtCHX17. Biochimica et Biophysica Acta (BBA)-Biomembranes. 1858. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1983--1998. Elsevier

Anishkin, Andriy, Rempe, Susan, Vanegas, Juan, Rogers, David, Sukharev, Sergei(2015). Active Role of the Substrate During Catalysis by the Therapeutic Enzyme L-Asparaginase II. The FASEB Journal. 29. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 573--51. The Federation of American Societies for Experimental Biology

Anishkin, Andriy, Vanegas, Juan M, Rogers, David M, Sukharev, Sergei, Rempe, Susan B(2015). Active role of the substrate during catalysis by the therapeutic enzyme L-asparaginase II. Biophysical Journal. 108. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 223a. Elsevier

Anishkin, Andriy, Chang, Kai-Ti, Colombini, Marco(2015). Bcl-xL Destabilization of Ceramide Channels: Role of the Hydrophobic Groove. Biophysical Journal. 108. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 383a. Elsevier

Anishkin, Andriy, Li, Xiaofan, Liu, Hansi, van Rossum, Damian B, Chintapalli, Sree V, Sassic, Jessica K, Gallegos, David, Pivaroff-Ward, Kendra, Jegla, Timothy(2015). Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4, 5-bisphosphate. Journal of General Physiology. 146. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 357--374. The Rockefeller University Press

Anishkin, Andriy, Vanegas, Juan M, Rogers, David M, Lorenzi, Philip L, Chan, Wai Kin, Purwaha, Preeti, Weinstein, John N, Sukharev, Sergei, Rempe, Susan B(2015). Catalytic role of the substrate defines specificity of therapeutic L-asparaginase. Journal of molecular biology. 427. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2867--2885. Academic Press

Anishkin, Andriy, Chang, Kai-Ti, Patwardhan, Gauri A, Beverly, Levi J, Siskind, Leah J, Colombini, Marco(2015). Ceramide channels: destabilization by Bcl-xL and role in apoptosis. Biochimica et Biophysica Acta (BBA)-Biomembranes. 1848. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2374--2384. Elsevier

Anishkin, Andriy, Teng, Jinfeng, Loukin, Stephen H, Kung, Ching(2015). L596--W733 bond between the start of the S4--S5 linker and the TRP box stabilizes the closed state of TRPV4 channel. Proceedings of the National Academy of Sciences. 112. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3386--3391. National Academy of Sciences

Anishkin, Andriy, Pudrovska, Tetyana(2015). Clarifying the positive association between education and prostate cancer: a Monte Carlo simulation approach. Journal of Applied Gerontology. 34. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 293--316. SAGE Publications Sage CA: Los Angeles, CA

Anishkin, Andriy, Li, Xiaofan, Liu, Hansi, Chu Luo, Jose, Rhodes, Sarah A, Trigg, Liana M, Van Rossum, Damian B, Diatta, Fortunay H, Sassic, Jessica K, Simmons, David K, et al.(2015). Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans. Proceedings of the National Academy of Sciences. 112. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E1010--E1019. National Academy of Sciences

Anishkin, Andriy, Chintapalli, Sree V, Bhardwaj, Gaurav, Patel, Reema, Shah, Natasha, Patterson, Randen L, Van Rossum, Damian B, Adams, Sean H(2015). Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin. PloS one. 10. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e0128496. Public Library of Science San Francisco, CA USA

Anishkin, Andriy, Cetiner, Ugur, Sukharev, Sergei, Rowe, Ian Donald, Mayhew, Christina(2015). The Electrophysiology of Mechanosensitive Channels in Pseudomonas aeruginosa. Biophysical Journal. 108. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 565a. Elsevier

Anishkin, Andriy, Teng, Jinfeng, Loukin, Stephen, Kung, Ching(2015). The L596-W733 Bond between S4-S5 Linker and TRP Domain Maintains Basal Activity and Enables Inactivation of TRPV4. Biophysical Journal. 108. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 37a. Elsevier

Anishkin, Andriy, Teng, Jinfeng, Loukin, Stephen, Kung, Ching(2015). The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements. Pflügers Archiv-European Journal of Physiology. 467. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 27--37. Springer Berlin Heidelberg Berlin/Heidelberg

Anishkin, Andriy, Rowe, Ian, Belyy, Vladislav, Sintim, Herman, Huq, Anwar, Sukharev, Sergei(2014). Emerging Electrophysiology of Facultative Bacterial Pathogens. Biophysical Journal. 106. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 560a. Elsevier

Anishkin, Andriy, Loukin, Stephen H, Teng, Jinfeng, Kung, Ching(2014). Feeling the hidden mechanical forces in lipid bilayer is an original sense. Proceedings of the National Academy of Sciences. 111. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7898--7905. National Academy of Sciences

Anishkin, Andriy, Lindy, Amanda S, Parekh, Puja K, Zhu, Richard, Kanju, Patrick, Chintapalli, Sree V, Tsvilovskyy, Volodymyr, Patterson, Randen L, Van Rossum, Damian B, Liedtke, Wolfgang B(2014). TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour. Nature communications. 5. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4734. Nature Publishing Group UK London

Anishkin, Andriy, Rowe, Ian, Sukharev, Sergei(2014). The Coupling of Tension and Crowding Sensing in the Bacterial Channel MscS. Biophysical Journal. 106. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 560a. Elsevier

Anishkin, Andriy, Rowe, Ian, Kamaraju, Kishore, Yoshimura, Kenjiro, Sukharev, Sergei(2014). The cytoplasmic cage domain of the mechanosensitive channel MscS is a sensor of macromolecular crowding. Journal of General Physiology. 143. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 543--557. The Rockefeller University Press

Anishkin, Andriy, Chan, Wai Kin, Lorenzi, Philip L, Purwaha, Preeti, Rogers, David M, Sukharev, Sergei, Rempe, Susan B, Weinstein, John N(2014). The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells. Blood, The Journal of the American Society of Hematology. 123. (23). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3596--3606. American Society of Hematology Washington, DC

Anishkin, Andriy, Pudrovska, Tetyana(2013). Early-life socioeconomic status and physical activity in later life: evidence from structural equation models. Journal of Aging and Health. 25. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 383--404. SAGE Publications Sage CA: Los Angeles, CA

Anishkin, Andriy, Yoshimura, Kenjiro, Rowe, Ian, Cember, Abigail, Sukharev, Sergei(2013). Gate Coupling to the Mechanical Stimulus Depends on Electrostatic Interactions between the Transmembrane and Cytoplasmic Domains. Biophysical Journal. 104. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 468a. Elsevier

Chintapalli, Sree V, Bhardwaj, Gaurav, Babu, Jagadish, Hadjiyianni, Loukia, Hong, Yoojin, Todd, George K, Boosalis, Casey A, Zhang, Zhenhai, Zhou, Xiaofan, Ma, Hong, et al.(2013). Reevaluation of the evolutionary events within recA/RAD51 phylogeny. BMC genomics. 14. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 240. BioMed Central London

Anishkin, Andriy, Kung, Ching(2013). Stiffened lipid platforms at molecular force foci. Proceedings of the National Academy of Sciences. 110. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4886--4892. National Academy of Sciences

Anishkin, Andriy, Pudrovska, Tetyana, Shen, Yifang(2012). Early-life socioeconomic status and the prevalence of breast cancer in later life. Research on aging. 34. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 302--320. SAGE Publications Sage CA: Los Angeles, CA

Anishkin, Andriy, Chintapalli, Sree V, Bhardwaj, Gaurav, Babu, Jagadish, Hadjiyianni, Loukia, Hong, Yoojin, Zhang, Zhenhai, Zhou, Xiaofan, Ma, Hong, van Rossum, Damian B, et al.(2012). Extraction of Deep Phylogenetic Signal and Improved Resolution of Evolutionary Events within the recA/RAD51 Phylogeny. arXiv preprint arXiv:1206.3340.

Anishkin, Andriy, Rowe, Ian, Kamaraju, Kishore, Boer, Miriam, Belyy, Vladislav, Sukharev, Sergei(2012). The hollow domain of the mechanosensitive channel MscS is a sensor of cytoplasmic crowding. Biophysical Journal. 102. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 121a. Elsevier

Anishkin, Andriy, Boer, Miriam, Sukharev, Sergei(2011). Adaptive MscS gating in the osmotic permeability response in E. coli: the question of time. Biochemistry. 50. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4087--4096. American Chemical Society

Anishkin, Andriy, Maksaev, Grigory, Milac, Adina, Guy, H Robert, Sukharev, Sergei(2011). Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1: comparisons with structural models. Channels. 5. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 34--42. Taylor \& Francis

Anishkin, Andriy, Yoshimura, Kenjiro, Kamaraju, Kishore, Belyy, Vladislav, Sukharev, Sergei(2011). Membrane tension and cytoplasmic crowding pressure: the multimodal mechanism of the mechanosensitive channel MscS. Biophysical Journal. 100. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 279a. Elsevier

Anishkin, Andriy, Milac, Adina, Fatakia, Sarosh N, Chow, Carson C, Sukharev, Sergei, Guy, H Robert(2011). Structural models of TREK channels and their gating mechanism. Channels. 5. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 23--33. Taylor \& Francis

Anishkin, Andriy, Su, Zhenwei, Kung, Ching, Saimi, Yoshiro(2011). The core domain as the force sensor of the yeast mechanosensitive TRP channel. Journal of General Physiology. 138. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 627--640. The Rockefeller University Press

Anishkin, Andriy, Kamaraju, Kishore, Belyy, Vladislav, Rowe, Ian, Sukharev, Sergei(2011). The pathway and spatial scale for MscS inactivation. Journal of General Physiology. 138. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 49--57. The Rockefeller University Press

Anishkin, Andriy, Belyy, Vladislav, Kamaraju, Kishore, Akitake, Bradley, Sukharev, Sergei(2010). Adaptive behavior of bacterial mechanosensitive channels is coupled to membrane mechanics. Journal of General Physiology. 135. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 641--652. The Rockefeller University Press

Anishkin, Andriy, Shafrir, Yinon, Durell, Stewart R, Guy, H Robert(2010). Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils. Proteins: Structure, Function, and Bioinformatics. 78. (16). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3458--3472. Wiley Subscription Services, Inc., A Wiley Company Hoboken

Anishkin, A, Kamaraju, K, Sukharev, S, Ermakov, Yu A(2010). Cross-linking of phosphatidylserine by lanthanide ions: macroscopic parameters of binding and atomic details of ion coordination.

Anishkin, Andriy, Yoshimura, Kenjiro, Kamaraju, Kishore, Belyy, Vladislav, Liu, Naili, Sukharev, Sergei(2010). Electrostatic Interactions Between the Transmembrane and Cytoplasmic Domains Critically Stabilize Tension-Sensitive States in MSCS. Biophysical Journal. 98. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 228a. Elsevier

Anishkin, A, Akitake, B, Kamaraju, K, Chiang, CS, Sukharev, S(2010). Hydration properties of mechanosensitive channel pores define the energetics of gating. Journal of Physics: Condensed Matter. 22. (45). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 454120.

Anishkin, Andriy, Kamaraju, Kishore, Liu, Naili, Sukharev, Sergei(2010). Inactivation of the Bacterial Mechanosensitive Channel MscL Involves Flexible Transmembrane Helices and a ‘Dry’Gate. Biophysical Journal. 98. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 324a. Elsevier

Anishkin, Andriy, Milac, Adina L, Fatakia, Sarosh N, Chow, Carson C, Sukharev, Sergei, Guy, Robert H(2010). Structural Models of Two-Pore-Domain Potassium Channels Focus on TREK. Biophysical Journal. 98. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 228a. Elsevier

Anishkin, Andriy, Milac, Adina L, Guy, H Robert(2010). Symmetry-restrained molecular dynamics simulations improve homology models of potassium channels. Proteins: Structure, Function, and Bioinformatics. 78. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 932--949. Wiley Subscription Services, Inc., A Wiley Company Hoboken

Anishkin, Andriy, Belyy, Vladislav, Kamaraju, Kishore, Liu, Naili, Sukharev, Sergei(2010). The tension-transmitting'clutch'in the mechanosensitive channel MscS. Nature structural & molecular biology. 17. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 451--458. Nature Publishing Group US New York

Anishkin, Andriy, Milac, Adina L, Guy, H Robert(2009). Accuracy of Ion Channels Homology Models is Significantly Improved by Symmetry-Restrained Molecular Dynamics Simulations. Biophysical Journal. 96. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 654a. Elsevier

Anishkin, Andriy, Belyy, Vladislav, Kamaraju, Kishore, Akitake, Bradley, Sukharev, Sergei(2009). Adaptive Behavior of Bacterial Mechanosensitive Channels in Excised Patches is Coupled to Membrane Mechanics. Biophysical Journal. 96. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 256a. Elsevier

Anishkin, Andriy, Sukharev, Sergei(2009). State-stabilizing interactions in bacterial mechanosensitive channel gating and adaptation. Journal of Biological Chemistry. 284. (29). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 19153--19157. Elsevier

Anishkin, Andriy, Sukharev, Sergei(2009). The Extrapolated Motion Protocol For Molecular Dynamics Simulations: Predicting Large-scale Conformational Transitions In Mechanosensitive Channels. Biophysical Journal. 96. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 406a. Elsevier

Anishkin, Andriy, Akitake, Bradley, Sukharev, Sergei(2008). Characterization of the resting MscS: modeling and analysis of the closed bacterial mechanosensitive channel of small conductance. Biophysical journal. 94. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1252--1266. Elsevier

Anishkin, Andriy, Kamaraju, Kishore, Sukharev, Sergei(2008). Mechanosensitive channel MscS in the open state: modeling of the transition, explicit simulations, and experimental measurements of conductance. The Journal of general physiology. 132. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 67--83. Rockefeller University Press

Anishkin, Andriy, Akitake, Bradley, Spelbrink, Robin EJ, Killian, J Antoinette, de Kruijff, Ben, Sukharev, Sergei(2007). 2, 2, 2-Trifluoroethanol changes the transition kinetics and subunit interactions in the small bacterial mechanosensitive channel MscS. Biophysical journal. 92. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2771--2784. Elsevier

Anishkin, Andriy, Akitake, Bradley, Spelbrink, Robin EJ, Killian, J Antoinette, Kruijff, Ben de, Sukharev, Sergei(2007). Channels, Receptors, and Electrical Signaling-2, 2, 2-Trifluoroethanol Changes the Transition Kinetics and Subunit Interactions in the Small Bacterial Mechanosensitive Channel MscS. Biophysical Journal. 92. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2771--2784. New York: Rockefeller University Press.

Anishkin, Andriy, Akitake, Bradley, Liu, Naili, Sukharev, Sergei(2007). Straightening and sequential buckling of the pore-lining helices define the gating cycle of MscS. Nature structural & molecular biology. 14. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1141--1149. Nature Publishing Group US New York

Anishkin, Andriy, Sukharev, Sergei, Akitake, Bradley(2007). The bacterial mechanosensitive channel MscS: Emerging principles of gating and modulation. Current topics in membranes. 58. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 235--267. Academic Press

Anishkin, Andriy, Su, Zhenwei, Zhou, Xinliang, Haynes, W John, Loukin, Stephen H, Saimi, Yoshiro, Kung, Ching(2007). Yeast gain-of-function mutations reveal structure--function relationships conserved among different subfamilies of transient receptor potential channels. Proceedings of the National Academy of Sciences. 104. (49). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 19607--19612. National Academy of Sciences

Anishkin, Andriy, Zhou, Xinliang, Su, Zhenwei, Haynes, W John, Friske, Eric M, Loukin, Stephen H, Kung, Ching, Saimi, Yoshiro(2007). Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate. Proceedings of the National Academy of Sciences. 104. (39). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 15555--15559. National Academy of Sciences

Anishkin, A, Sukharev, S, Colombini, M(2006). Searching for the molecular arrangement of transmembrane ceramide channels. Biophysical journal. 90. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2414--2426. Elsevier

Anishkin, Andriy, Sukharev, Sergei(2005). Explicit channel conductance: can it be computed?. Biophysical journal. 88. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3742--3743. Elsevier

Anishkin, Andriy, Chiang, Chien-Sung, Sukharev, Sergei(2005). Gain-of-function mutations reveal expanded intermediate states and a sequential action of two gates in MscL. The Journal of general physiology. 125. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 155--170. Rockefeller University Press

Anishkin, Andriy, Kung, Ching(2005). Microbial mechanosensation. Current opinion in neurobiology. 15. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 397--405. Elsevier Current Trends

Anishkin, Andriy, Sukharev, Sergei, Chiang, Chien-Sung, Betanzos, Monica, Robert Guy, H(2005). MscL, a bacterial mechanosensitive channel. Bacterial ion channels and their eukaryotic homologs. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 259--290. ASM Press Washington, DC, USA

Anishkin, Andriy, Akitake, Bradley, Sukharev, Sergei(2005). The “dashpot” mechanism of stretch-dependent gating in MscS. The Journal of general physiology. 125. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 143--154. Rockefeller University Press

Anishkin, Andriy, Chiang, Chien-Sung, Sukharev, Sergei(2004). Channels, Receptors, and Transporters-Gating of the Large Mechanosensitive Channel In Situ: Estimation of the Spatial Scale of the Transition from Channel Population Responses. Biophysical Journal. 86. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2846--2861. New York: Rockefeller University Press.

Anishkin, Andriy, Chiang, Chien-Sung, Sukharev, Sergei(2004). Gating of the large mechanosensitive channel in situ: estimation of the spatial scale of the transition from channel population responses. Biophysical journal. 86. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2846--2861. Elsevier

Anishkin, Andriy, Sukharev, Sergei(2004). Mechanosensitive channels: what can we learn from ‘simple’model systems?. Trends in neurosciences. 27. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 345--351. Elsevier

Anishkin, Andriy, Sukharev, Sergei(2004). Water dynamics and dewetting transitions in the small mechanosensitive channel MscS. Biophysical journal. 86. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2883--2895. Elsevier

Anishkin, Andriy, Gendel, Vyacheslav, Sharifi, Neda A, Chiang, Chien-Sung, Shirinian, Lena, Guy, H Robert, Sukharev, Sergei(2003). On the conformation of the COOH-terminal domain of the large mechanosensitive channel MscL. The Journal of general physiology. 121. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 227--244. Rockefeller University Press

Lemeshko, VV, Anishkin, AG(1998). Mathematical modeling of energy coupling in mitochondria in frames of proton-chemical hypothesis. Biofizika. 43. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 308--314.

Lemeshko, VV, Anishkin, AG(1998). Mathematical simulation of energy coupling in mitochondria within the framework of the proton-chemical hypothesis. Biophysics. 43. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 285--291. Pergamon Press

Anishkin, Andriy, Dave, Noopur, Cetiner, Ugur, Arroyo, Daniel, Fonbuena, Joshua, Tiwari, Megna, Barrera, Patricia, Lander, Noelia, Sukharev, Sergei, Jimenez, VeronicaA novel mechanosensitive channel controls osmoregulation, differentiation.

Anishkin, Andriy, Patro, Robert, Kim, Youngmin, Ip, Cheuk Yiu, Sukharev, Sergei, O’Leary, Dianne P, Varshney, AmitabhSalient Frame Detection for Molecular Dynamics Simulations.

Anishkin, Andriy, Chow, C, Milac, Adina, Sukharev, SergeiStructural models of TREK channels and their gating mechanism.

Anishkin, AG, Lemeshko, VVTHEORETICAL DEPENDENCE OF PHOSPHATE POTENTIAL ON MAGNITUDE OF PROTONMOTIVE FORCE FOR TWO-ELECTRON PROTON-CHEMICAL COUPLING POINT MODEL.

PREPRINT

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). COI Form_Karine from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). COI Form_Karine from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). COI Form_Karine from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). Data from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). Data from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). Data from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). Supplementary Data from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). Supplementary Data from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

Andriy Anishkin, Wai-Kin Chan, Thomas D. Horvath, Lin Tan, Todd Link, Karine G. Harutyunyan, Michael A. Pontikos, Di Du, Leona A. Martin, Eric Yin, et al. (2023). Supplementary Data from Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia .

R. R. Tatikonda, A. Anishkin, S. Sukharev, J. M. Vanegas (2020). Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach .

BOOK CHAPTER

Anishkin, Andriy, Sukharev, Sergei(2023). Mechanosensitive channels and their emerging gating mechanisms. Textbook of Ion Channels Volume I. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 61--86. CRC Press

CONFERENCE PAPER

Anishkin, Andriy, Elena Gomez, Gabriela, Maria Delfino, Jose, Wang, Yan, Sukharev, Sergei(2019). MAPPING ACCESSIBILITY IN THE BACTERIAL MECHANOSENSITIVE CHANNEL MSCS TO A SMALL PHOTOREACTIVE PROBE. PROTEIN SCIENCE. 28. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 90--90.

Lubkowski, J, Anishkin, A, Chan, WK, Fushman, D, Lorenzi, PL, Rempe, SB, Sukharev, S, Vanegas, JM, Wlodawer, A, Weinstein, JN(2019). New evidence supporting the ping-pong mechanism of catalysis by L-asparaginases. FEBS OPEN BIO. 9. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 258--258.

Lubkowski, J, Anishkin, A, Chan, WK, Fushman, D, Lorenzi, PL, Rempe, SB, Sukharev, S, Vanegas, JM, Weinstein, JN, Wlodawer, A(2018). Bacterial L-asparaginases: old friend and persistent foe. FEBS OPEN BIO. 8. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 282--283.

Anishkin, Andriy, Milac, Adina L, Fatakia, Sarosh N, Chow, Carson C, Sukharev, Sergei, Guy, H Robert(2011). Symmetry constraints improve accuracy of ion channels models. Application to two-pore-domain channels. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 40. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 113--113.

Anishkin, Andriy, Akitake, Bradley, Liu, Naili, Sukharev, Sergei(2007). Bend and buckle: The gating cycle of MscS depends on alternate kinking of the pore-lining TM3 helices. BIOPHYSICAL JOURNAL. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 113A--114A.

Anishkin, Andriy, Akitake, Bradley, Sukharev, Sergei(2007). Gating of MscS Explored by the ‘Extrapolated Motion’Technique and Symmetry-Driven Simulated Annealing. BIOPHYSICAL JOURNAL. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 114A--114A.

Anishkin, Andriy, Sukharev, Sergei, Akitake, Bradley(2007). PHYS 184-Gating mechanism of the bacterial mechanosensitive channel MscS. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 234.

Anishkin, Andriy, Colombini, Marco, Siskind, Leah J, Stiban, Johnny(2007). Permeabilization of the outer membrane by ceramide channels: role in apoptosis. BIOPHYSICAL JOURNAL. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1A--1A.

Anishkin, Andriy, Shafrir, Yinon, Durell, Stewart R, Guy, H Robert(2007). Structural models of soluble and membrane Abeta oligomers. BIOPHYSICAL JOURNAL. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 194A--194A.

Anishkin, A, Sukharev, S, Colombini, M(2004). Searching for the molecular arrangement of transmembrane ceramide channels. BIOPHYSICAL JOURNAL. 86. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 194A--194A.

Chiang, CS, Anishkin, A, Sukharev, S(2003). Gain-of-function mutations in the pore region reveal pre-expanded intermediate states and sequential action of two gates in MscL. BIOPHYSICAL JOURNAL. 84. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 21A--21A.

Anishkin, A, Chiang, CS, Sukharev, S(2003). Gating parameters of the large mechanosensitive channel in situ. BIOPHYSICAL JOURNAL. 84. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 232A--233A.

ANISHKIN, ANDRIY, MILAC, ADINA L, FATAKIA, SAROSH N, CHOW, CARSON C, SUKHAREV, SERGEI, GUY, H ROBERT, PETRESCU, ANDREI-JCOMPUTATIONAL MODELS OF MECHANOSENSITIVE TREK CHANNELS AND THEIR GATING MECHANISM ARE SUPPORTED BY EXPERIMENTAL DATA. 11 th National Conference of Biophysics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 69.

OTHER

Anishkin, Andriy, Sukharev, Sergei(2017). Channel disassembled: Pick, tweak, and soak parts to soften. Taylor \& Francis

ANISHKIN, Andriy, Rempe, Susan, Rogers, David M, SUKHAREV, Sergei, Lorenzi, Philip L, Chan, Wai Kin, Weinstein, John N(2016). Therapeutic asparaginases.

Anishkin, Andriy, Lorenzi, Philip L, Chan, Wai Kin, Purwaha, Preeti, Rogers, David M, Sukharev, Sergei, Rempe, Susan B, Weinstein, John N(2013). The Glutaminase Activity Of L-Asparaginase Is Not Required For Anticancer Activity Against Asns-Negative Cell Lines. American Society of Hematology Washington, DC

Anishkin, Andriy, Kim, Youngmin, Patro, Robert, Yiu Ip, Cheuk, O’Leary, Dianne P(2011). Salient Frame Detection for Molecular Dynamics Simulations. Schloss Dagstuhl--Leibniz-Zentrum f{\"u}r Informatik

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Anishkin, Andriy, Vanegas, Juan M, Rogers, David M, Lorenzi, Philip L, Chan, Wai Kin, Purwaha, Preeti, Weinstein, John, Sukharev, Sergei, Rempe, Susan(2015). Probing Small-Molecule Degradation to Counter Enzyme Promiscuity.

Anishkin, Andriy, Rempe, Susan, Vanegas, Juan M, Rogers, David, Chan, Wai Kin, Lorenzi, Phil, Purwaha, Preeti, Weinstein, John, Sukharev, Sergei(2015). Substrate recognition by therapeutic L-Asparaginase: Asn vs Gln.

Anishkin, Andriy, Rempe, Susan, Chan, Wai Kin, Link, Todd, Sukharev, Sergei, Weinstein, John, Lorenzi, Phil(2014). The glutaminase activity of L-asparaginase determines its anticancer activity against ASNS-positive cancer cells.