Profile Details

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Hire Amine B.

United Kingdom

USD 70 /hr

Genome editing scientist with 9+ years experience in CRISPR system. Expertise in mESC, hiPS cells; organoids and animals

Profile Summary

I jumped into the world of genome editing and CRISPR/Cas9 during my PhD when I was working on the role of MICRORNA in fish reproduction, to investiagte the role of some interesting candidates, I generated my first Knock-Out fish model using CRISPR and then I decided to focus my career on gene editing. I joined the University of Oxford as a postdoctoral researcher in gene editing technologies. I gained an extensive expertise in gene editing on mouse model, mouse embryonic stem cells, human induced pluripotent cells and organoids. Today, my main interest is to help to drive the gene editing into the clinics and develop innovative therapies.

Subject Matter Expertise

• ★ Stem Cell Research
• ★ Genetic Engineering
• ★ Gene Editing/CRISPR
• ☆ Molecular Biology
• ☆ Next Generation Sequencing (NGS)
• ☆ Cell Culture
• ☆ Gene Therapy
• ☆ Project Management

Services

• Research
• Consulting
• Data & AI
• Product Development

Research Market Research, Feasibility Study

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Product Development Formulation, Product Evaluation, Concept Development

Work Experience

University of Oxford

- Present

Education

PhD (Biology)

University of Rennes 1

October 2013 - October 2016

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Chris Preece and Samy Alghadban and Amine Bouchareb and Daniela Moralli and Daniel Biggs and Benjamin Davies(2021). Replacement of surgical vasectomy through the use of wild-type sterile hybrids . Lab Animal. 50. (2). p. 49--52. Springer Science and Business Media {LLC}

Samy Alghadban and Amine Bouchareb and Robert Hinch and Polinka Hernandez-Pliego and Daniel Biggs and Chris Preece and Benjamin Davies(2020). Electroporation and genetic supply of Cas9 increase the generation efficiency of CRISPR/Cas9 knock-in alleles in C57BL/6J mouse zygotes . Scientific Reports. 10. (1). Springer Science and Business Media {LLC}

St{\'{e}}phanie Gay and J{\'{e}}r{\^{o}}me Bugeon and Amine Bouchareb and Laure Henry and Clara Delahaye and Fabrice Legeai and J{\'{e}}r{\^{o}}me Montfort and Aur{\'{e}}lie Le Cam and Anne Siegel and Julien Bobe and Violette Thermes(2018). MiR-202 controls female fecundity by regulating medaka oogenesis . PLOS Genetics. 14. (9). p. e1007593. Public Library of Science ({PLoS})

B. Sadoul, S. Alfonso, E. Bessa, A. Bouchareb, E. Blondeau-Bidet, P. Clair, B. Chatain, M.L. Bégout, B. Geffroy(2018). Enhanced brain expression of genes related to cell proliferation and neural differentiation is associated with cortisol receptor expression in fishes . General and Comparative Endocrinology. Elsevier {BV}

Geffroy, B., Sadoul, B., Bouchareb, A., Prigent, S., Bourdineaud, J.-P., Gonzalez-Rey, M., Morais, R.N., Mela, M., Carvalho, L.N., Bessa, E.(2018). Nature-based tourism elicits a phenotypic shift in the coping abilities of fish . Frontiers in Physiology. 9. (FEB).

Bouchareb, A., Le Cam, A., Montfort, J., Gay, S., Nguyen, T., Bobe, J., Thermes, V.(2017). Genome-wide identification of novel ovarian-predominant miRNAs: New insights from the medaka (Oryzias latipes) . Scientific Reports. 7.