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Profile Details
Hire Dr. Vikas J.
India
15+ years experience in Molecular Biology, Biochemistry, Recombinant DNA Technology
Profile Summary
Subject Matter Expertise
Services
Research
Gray Literature Search,
Systematic Literature Review,
Secondary Data Collection
Consulting
Scientific and Technical Consulting
Work Experience
Associate Professor
Indian Institute of Science Education and Research Bhopal
September 2015 - Present 
Assistant Professor
Indian Institute of Science Education and Research Bhopal
June 2009 - August 2015
Education
PhD (Molecular Biophysics Unit)
Indian Institute of Science
August 2001 - July 2006
M. Sc. (Biosciences)
Jamia Millia Islamia
August 1999 - July 2001
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Vikas Jain, Surya Pratap Seniya, Joyoti Basu, Priya Yadav (2020). Construction of E. coli—Mycobacterium shuttle vectors with a variety of expression systems and polypeptide tags for gene expression in mycobacteria . PLOS ONE.
(2019). Understanding the role of the lysozyme-like domain of D29 mycobacteriophage-encoded endolysin in host cell lysis and phage propagation . Microbiology. 165. (9). p. 1013--1023. Microbiology Society
Vikas Jain, Abhishek Anil Dubey(2019). Mycofactocin is essential for the establishment of methylotrophy in Mycobacterium smegmatis . Biochemical and Biophysical Research Communications. Elsevier {BV}
Vikas Jain, Varsha Patil, William W. Metcalf(2019). Insights into the Physiology and Metabolism of a Mycobacterial Cell in an Energy-Compromised State . Journal of Bacteriology. American Society for Microbiology
Vikas Jain, Abhishek Anil Dubey, Volker Müller(2019). MnoSR Is a Bona Fide Two-Component System Involved in Methylotrophic Metabolism in Mycobacterium smegmatis . Applied and Environmental Microbiology. American Society for Microbiology
(2018). Methylotrophy in Mycobacteria: Dissection of the Methanol Metabolism Pathway in Mycobacterium smegmatis . Journal of Bacteriology. p. JB.00288--18. American Society for Microbiology
Vikas Jain, Radhakrishnan Mahalakshmi, Svetlana Rajkumar Maurya, Bhawna Burdak, Parini Surti, Manoj S. Patel(2017). Structural plasticity of T4 transcription co-activator gp33 revealed by a protease-resistant unfolded state . Biochemical and Biophysical Research Communications. 492. (1). p. 61--66. Elsevier {BV}
(2017). Identification and Characterization of an Inside-Out Folding Intermediate of T4 Phage Sliding Clamp . Biophysical Journal. 113. (8). p. 1738--1749. Elsevier {BV}
(2017). Dissecting the structure-function relationship in lysozyme domain of mycobacteriophage D29-encoded peptidoglycan hydrolase . FEBS Letters. Wiley-Blackwell
Vikas Jain, Himanshu Joshi(2017). Novel method to rapidly and efficiently lyse Escherichia coli for the isolation of recombinant protein . Analytical Biochemistry. 528. p. 1--6. Elsevier {BV}
(2017). Robust high throughput real-time monitoring assay for the specific screening of bacterial cell envelope inhibitors. Proceedings of the Indian National Science Academy.
Vikas Jain, Manika Indrajit Singh, Bylapudi Ganesh(2017). On the domains of T4 phage sliding clamp gp45: An intermolecular crosstalk governs structural stability and biological activity . Biochimica et Biophysica Acta (BBA) - General Subjects. 1861. (1). p. 3300--3310. Elsevier {BV}
(2017). On the domains of T4 phage sliding clamp gp45: An intermolecular crosstalk governs structural stability and biological activity . Biochimica et Biophysica Acta - General Subjects. 1861. (1). p. 3300-3310.
(2016). Mycobacteriophage D29 holin C-terminal region functionally assists in holin aggregation and bacterial cell death . FEBS Journal. 283. (1). p. 173-190.
Singh, M.I., Jain, V.(2016). Molecular Dissection of the Homotrimeric Sliding Clamp of T4 Phage: Two Domains of a Subunit Display Asymmetric Characteristics . Biochemistry. 55. (3). p. 588-596.
(2016). Rapid and robust PCR-based all-recombinant cloning methodology . PLoS ONE. 11. (3).
Lella, M., Kamilla, S., Lella, M., Kamilla, S., Jain, V., Mahalakshmi, R.(2016). Molecular Mechanism of Holin Transmembrane Domain i in Pore Formation and Bacterial Cell Death . ACS Chemical Biology. 11. (4). p. 910-920.
(2015). Modulation of domain–domain interaction and protein function by a charged linker: A case study of mycobacteriophage D29 endolysin . FEBS Letters. 589. (6). p. 695--701. Elsevier {BV}
(2015). Cell Penetrating Synthetic Antimicrobial Peptides (SAMPs) Exhibiting Potent and Selective Killing of Mycobacterium by Targeting Its DNA . Chem. Eur. J. 21. (9). p. 3540--3545. Wiley-Blackwell
Pohane, A.A., Jain, V.(2015). Insights into the regulation of bacteriophage endolysin: Multiple means to the same end . Microbiology (United Kingdom). 161. (12). p. 2269-2276.
(2015). Novel pppGpp binding site at the C-terminal region of the Rel enzyme from Mycobacterium smegmatis . FEBS Journal. 282. (19). p. 3773-3785.
(2014). Evidence of a conserved intrinsically disordered region in the C-terminus of the stringent response protein Rel from mycobacteria . FEBS Letters. Elsevier BV
(2014). Molecular dissection of phage endolysin: An interdomain interaction confers host specificity in Lysin A of Mycobacterium phage D29 . Journal of Biological Chemistry. American Society for Biochemistry & Molecular Biology (ASBMB)
Pohane, A.A., Pohane, A.A., Pohane, A.A., Patidar, N.D., Jain, V.(2014). Modulation of domain-domain interaction and protein function by a charged linker: A case study of mycobacteriophage D29 endolysin . FEBS Letters.
(2014). Evidence of a conserved intrinsically disordered region in the C-terminus of the stringent response protein Rel from mycobacteria . FEBS Letters. 588. (9). p. 1839-1849.
(2013). Tagging the Expressed Protein with 6 Histidines: Rapid Cloning of an Amplicon with Three Options . Plos One. 8. (5).
(2013). Tagging the Expressed Protein with 6 Histidines: Rapid Cloning of an Amplicon with Three Options . PLoS ONE. 8. (5).
(2011). Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the beta-subunit flap domain of Escherichia coli RNA polymerase . Proceedings of the National Academy of Sciences of the United States of America. 108. (50). p. 19961-19966.
(2011). Crystal structure of the bacteriophage T4 latetranscription coactivator gp33 with the β-subunit flap domain of Escherichia coli RNA polymerase . Proceedings of the National Academy of Sciences of the United States of America. 108. (50). p. 19961-19966.
(2007). Synthesis and hydrolysis of pppGpp in mycobacteria: A ligand mediated conformational switch in Rel . Biophysical Chemistry. 127. (1-2). p. 41-50.
Jain, V., Kumar, M., Jain, V., Kumar, M., Jain, V., Kumar, M., Chatterji, D.(2006). ppGpp: Stringent response and survival . Journal of Microbiology. 44. (1). p. 1-10.
(2006). Molecular dissection of the mycobacterial stringent response protein Rel . Protein Science. 15. (6). p. 1449-1464.
(2006). Molecular dissection of the mycobacterial stringent response protein Rel . Protein Science. 15. (6). p. 1449-1464.
(2005). Identification and characterization of rel promoter element of Mycobacterium tuberculosis . Gene. 351. p. 149-157.
Jain, V., Sujatha, S., Ojha, A.K., Chatterji, D.(2005). Identification and characterization of rel promoter element of Mycobacterium tuberculosis . Gene. 351. p. 149-157.
(2002). Sugars have potential to curtail oxygenase activity of Rubisco . Biochemical and Biophysical Research Communications. 298. (2). p. 247â??250. Elsevier BV
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