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Hire Dr. Vedangana S.

United States

USD 25 /hr

Freelance Science writer with academic research experience (PhD) with specialization in Cellular/Molecular Neuroscience

Profile Summary

I have been trained as a bench researcher in Neuroscience since 2012. For my Ph.D. studies in India, I evaluated beneficial effects of polysialic acid and its synthetic mimetics on axonal growth and neural repair following spinal cord injury in mice. During this time, I learned to perform thoracic spinal cord laminectomies and compression injuries. Also during this period, I gained extensive experience in tissue culture techniques and became proficient in culturing different primary neural cells (astrocytic, cortical, hippocampal, and microglial cells) and neural cell lines (C6 glioma, IMR-32 Neuroblastoma, U-87 MG astroglioma). I developed expertise cellular and molecular biology techniques such as immunohistochemistry, western blotting and co-immunoprecipitation and became proficient in microscopy and imaging techniques; in particular, confocal microscopy, scanning electron microscopy, and live cell imaging during Ph.D. Further, I became interested in the cell-cell interactions that regulate function of the nervous system. Therefore, for my first postdoctoral training in USA (2017), my work focused in examining the role of astrocytic Ca+2 signaling in the structural and synaptic plasticity associated with behavioral alterations in neurodevelopmental disorders such as fragile-X-syndrome. During that time, I learned cranial window implantation and two-photon imaging of astrocytes. I also learned single-cell RNA-seq and plasmid construction, which furthered my repertoire of molecular biology techniques. Having experience in cell-cell interactions, I returned to spinal cord injury research in 2018 in New York, where I studied the role of transcription factors in enhancing transplanted cell survival following spinal cord injury in rats.

Subject Matter Expertise

• ★ Molecular Biology
• ★ Neuroscience
• ★ Spinal Cord Injury
• ☆ Animal Behavior/Ethology
• ☆ Genetics
• ☆ Basic Immunology
• ☆ Histology
• ☆ Cell Culture
• ☆ Protein/Enzyme Engineering

Services

• Writing
• Research
• Data & AI

Writing Clinical Trial Documentation, Technical Writing, Newswriting

Research Fact Checking, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis

Work Experience

Postdoctoral Fellow

Weill Cornell Medicine

June 2018 - October 2018

Postdoctoral Research Associate

University of Nebraska Medical Center

June 2017 - 2018

Education

PhD (Department of Biotechnology)

Guru Nanak Dev University

August 2012 - December 2016

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2019). 5-Nonyloxytryptamine oxalate-embedded collagen-laminin scaffolds augment functional recovery after spinal cord injury in mice . Annals of the New York Academy of Sciences.

(2019). Synthesis, Characterization, and Evaluation of Surface and Thermal Properties and Cytotoxicity of 2-Hydroxy-3-Phenoxypropyl Imidazolium Bola-Type Gemini Amphiphiles . Journal of Surfactants and Detergents.

Vedangana Saini, Gabriele Loers, Steven Astafiev, Yuliya Hapiak, Bibhudatta Mishra, Sheraz Gul, Gurcharan Kaur, Melitta Schachner, Thomas Theis(2017). The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C . Journal of Neurochemistry. Wiley-Blackwell

Vedangana Saini, Natascha Schaefer, Carola Rotermund, Eva-Maria Blumrich, Mychael V. Lourenco, Pooja Joshi, Regina U. Hegemann, Sumit Jamwal, Nilufar Ali, Ezra Michelet García Romero, et al.(2017). The malleable brain: plasticity of neural circuits and behavior - A review from students to students . Journal of Neurochemistry. Wiley-Blackwell

Kaur, T., Singh, H., Mishra, R., Manchanda, S., Gupta, M., Saini, V., Sharma, A., Kaur, G.(2017). Withania somnifera as a potential anxiolytic and immunomodulatory agent in acute sleep deprived female Wistar rats . Molecular and Cellular Biochemistry. 427. (1-2). p. 91-101.

Saini, V., Lutz, D., Kataria, H., Kaur, G., Schachner, M., Loers, G.(2016). The polysialic acid mimetics 5-nonyloxytryptamine and vinorelbine facilitate nervous system repair . Scientific Reports. 6.

Mishra, R., Manchanda, S., Gupta, M., Kaur, T., Saini, V., Sharma, A., Kaur, G.(2016). Tinospora cordifolia ameliorates anxiety-like behavior and improves cognitive functions in acute sleep deprived rats . Scientific Reports. 6.

Saini, V., Loers, G., Kaur, G., Schachner, M., Jakovcevski, I.(2016). Impact of neural cell adhesion molecule deletion on regeneration after mouse spinal cord injury . European Journal of Neuroscience. 44. (1). p. 1734-1746.

Kaur, T., Manchanda, S., Saini, V., Lakhman, S.S., Kaur, G.(2016). Efficacy of anti-epileptic drugs in the treatment of tumor and its associated epilepsy: An in vitro perspective . Annals of Neurosciences. 23. (1). p. 33-43.

Loers, G., Saini, V., Mishra, B., Gul, S., Chaudhury, S., Wallqvist, A., Kaur, G., Schachner, M.(2016). Vinorelbine and epirubicin share common features with polysialic acid and modulate neuronal and glial functions . Journal of Neurochemistry. 136. (1). p. 48-62.

Loers, G., Saini, V., Mishra, B., Papastefanaki, F., Lutz, D., Chaudhury, S., Ripoll, D.R., Wallqvist, A., Gul, S., Schachner, M., et al.(2014). Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture . Journal of Neurochemistry. 128. (1). p. 88-100.