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USD 20 /hr
Hire Dr. Umasankar K.
India
USD 20 /hr

Medicinal Chemistry, Drug Design of molecules, Content writter, Pharmaceutical Sciences, Synthetic Organic Chemistry

Profile Summary
Subject Matter Expertise
Services
Writing Technical Writing
Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection
Consulting Scientific and Technical Consulting
Data & AI Statistical Analysis, Data Visualization
Product Development Formulation
Work Experience

Professor

KL College of Pharmacy, Koneru Lakshmaiah Education Foundation

May 2018 - Present

Professor

Vaagdevi College of Pharmacy

March 2008 - May 2018

Associate Professor

KLR Pharmacy College

November 2004 - March 2008

Assistant Professor

Sanjivani College of Pharmaceutical Sciences

July 2003 - October 2004

Assistant Professor

JKK Munirajah Medical Research Foundation College of Pharmacy

June 1998 - June 2003

Education

PhD (Pharmacy)

Jawaharlal Nehru Technological University, Hyderabad

July 2008 - December 2015

Master of Pharmacy

University College of Pharmaceutical Sciences, Kakatiya University, Warangal, Andhra Pradesh.

June 2000 - June 2002

Bachelor of Pharmacy

J. K. K. Munirajah Medical Research Foundation, College of Pharmacy, Komarapalayam- 638 183, The Tamil Nadu Dr. M. G. R. Medical University, Chennai, Tamil Nadu.

September 1992 - October 1997

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
U Praveen Kumar, GSN Koteswara Rao, A Rajasekhar Reddy, K Umasankar, Y Vangoori (2021). Protective effect of Acampe praemorsa (Roxb.) Blatt. & McCann against oxidative stress . Plant Science Today.
S Abdelsattar, ZA Kasemy, M Elsayed, TA Elrahem, SK Zewain (2021). Targeted metabolomics as a tool for the early diagnosis of Diabetic Kidney Disease in Type II Diabetes Mellitus patients . British Journal of Biomedical Science.
Kulandaivelu Umasankar, Bikash Ranjan Jena, Siva Prasad Panda, Suryakanta Swain, Gudhanti Siva Naga Koteswara Rao, Dalu Damayanthi, Debashish Ghose, Debi Prasad Pradhan(2021). Applications of QbD-based Software’s in Analytical Research and Development . Current Pharmaceutical Analysis. 16. Bentham Science Publishers Ltd.
Umasankar Kulandaivelu, Sahibzada Tasleem Rasool, Rajasekhar Reddy Alavala, Nagaraja Sreeharsha (2020). Non-Invasive Delivery of Nano-Emulsified Sesame Oil-Extract of Turmeric Attenuates Lung Inflammation . Pharmaceutics.
Umasankar Kulandaivelu, Sahibzada Tasleem Rasool, Rajasekhar Reddy Alavala, Nagaraja Sreeharsha (2020). Non-Invasive Delivery of Nano-Emulsified Sesame Oil-Extract of Turmeric Attenuates Lung Inflammation . Pharmaceutics.
(2020). Studies on Antidiabetic Activity of Atylosia Albicans in Streptozotocin-Induced Diabetic Rats . International Journal of Research in Pharmaceutical Sciences.
(2020). Applications of QbD-based software’s in Analytical Research and Development . Current Pharmaceutical Analysis.
Sharvana Bhava, B.S., Umasankar, K., Kottai Muthu, A.(2020). Studies on antidiabetic activity of Atylosia Albicans in Streptozotocin-Induced diabetic rats . International Journal of Research in Pharmaceutical Sciences. 11. (1). p. 416-424.
Bhava, B.S.S., Umasankar, K., Muthu, A.K.(2020). Screening of antidiabetic activity of delonix elata whole plant extracts in diabetic Wistar rats . International Journal of Pharmaceutical Research. 12. (3). p. 159-167.
(2019). Antidiabetic Activity of Chrozophorarottlerileaves extracts in streptozotocin induced diabetic rats . International Journal of Pharmaceutical Research.
(2019). Evaluation of Antiulcer Activity of Lawsonia inermis and Murraya koenigii Seed Extract in Ethanol-induced Gastric Mucosal Damage in Rats . Asian Journal of Biological Sciences.
(2019). Risk Assessment, Screening and Control of Elemental Impurities in Pharmaceutical Drug Products: A Review . Current Pharmaceutical Analysis.
Nallapati, S., Kulandaivelu, U., Rao, G.K., Panda, S.P., Alavala, R.R.(2019). Antidiabetic activity of Chrozophorarottlerileaves extracts in streptozotocin induced diabetic rats . International Journal of Pharmaceutical Research. 11. (4). p. 978-988.
Chawla, Rajesh Kumar and Panda, Subhranshu and Umasankar, Kulandaivelu and Panda, Siva Prasad and Damayanthi, Dalu(2019). Method Development and Validation for Quantitative Estimation of Calcium Acetate in Calcium Acetate Capsules by RP-HPLC using Indirect UV Method. INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH. 53. (3). p. S380--S386. ASSOC PHARMACEUTICAL TEACHERS INDIA AL-AMEEN COLL PHARMACY, OPP LALBACH MAIN~?
Chawla, R.K., Panda, S., Umasankar, K., Panda, S.P., Damayanthi, D.(2019). Method development and validation for quantitative estimation of calcium acetate in calcium acetate capsules by RP-HPLC using indirect UV method . Indian Journal of Pharmaceutical Education and Research. 53. (3). p. S380-S386.
(2018). Synthesis, Antimycobacterial Evaluation and Docking Studies of Some 7-Methyl-5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-ones . Chemical and Pharmaceutical Bulletin.
Alavala, R.R., Katahala, P., Thipparapu, G., Kulandaivelu, U., Boyapati, S., Mantripragada, B.R.(2018). Study of in vivo pharmacokinetic drug interactions of curcumin on tacrine . Asian Journal of Pharmaceutical and Clinical Research. 11. (9). p. 337-343.
Bandaru, Sharavanabhava and Kulandaivelu, Umasankar and others(2018). Neuroprotective and nootropic activity of Carica papaya seeds on Diabetes induced cognitive decline in rats. Iranian Journal of Pharmaceutical Sciences. 14. (3). p. 107--116. Iranian Association of Pharmaceutical Scientists
Malothu, N., Kulandaivelu, U., Jojula, M., Gunda, S.K., Akkinepally, R.R.(2018). Synthesis, antimycobacterial evaluation and docking studies of some 7-Methyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-ones . Chemical and Pharmaceutical Bulletin. 66. (10). p. 923-931.
Venkateshwarlu, E., Srilatha, K., Bhava, B.S.S., Umasankar, K.(2018). Neuroprotective and nootropic activity of carica papaya seeds on diabetes induced cognitive decline in rats . Iranian Journal of Pharmaceutical Sciences. 14. (3). p. 107-116.
(2016). Evaluation of Antioxidant, Antimicrobial and Anticancer activity of Thiazole Tagged Isatin Hydrazones . JOURNAL OF PHARMACEUTICAL CHEMISTRY.
(2016). Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3- d ]pyrimidin-4(3 H )-one schiff bases . Bioorganic & Medicinal Chemistry Letters.
Narender, M., Jaswanth, S.B., Umasankar, K., Malathi, J., Raghuram Reddy, A., Umadevi, K.R., Dusthackeer, A.V.N., Venkat Rao, K., Raghuram, R.A.(2016). Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases . Bioorganic and Medicinal Chemistry Letters. 26. (3). p. 836-840.
(2015). Synthesis and Antiviral Activity of Dihydropyrimidines - Ciprofloxacin Mannich bases Against Various Viral Strains . Anti-Infective Agents.
(2015). Synthesis, Antiglycating and Antioxidant activities of Triazolo hexahydroquinazolines . JOURNAL OF PHARMACEUTICAL CHEMISTRY.
(2015). Evaluation of diuretic activity of Syzygium cumini and its effect on prostaglandin system . Oriental Pharmacy and Experimental Medicine.
(2015). Evaluation of diuretic activity of Syzygium cumini and its effect on prostaglandin system . Oriental Pharmacy and Experimental Medicine.
Venkateshwarlu, E., Bhava, B.S.S., Kumar, R.S., Venkateshwar, R.J., Gouthami, E., Umasankar, K.(2015). Evaluation of diuretic activity of Syzygium cumini and its effect on prostaglandin system . Oriental Pharmacy and Experimental Medicine. 15. (1). p. 45-51.
Alavala, R.R., Kulandaivelu, U., Bonagiri, P., Boyapati, S., Jayaprakash, V., Subramaniam, A.T.(2015). Synthesis and antiviral activity of dihydropyrimidines – ciprofloxacin mannich bases against various viral strains . Anti-Infective Agents. 13. (2). p. 154-165.
Umasankar, K., Ramya, D.R., Nambikkairaj, B.(2015). Antioxidant potential of carvacrol studied in high-fat -fed and low-dose streptozotocin-induced experimental diabetic rats . Der Pharmacia Lettre. 7. (9). p. 124-131.
(2015). Synthesis and evaluation of neuropharmacological profile of isatin-3-[ N 2-(2-benzalaminothiazol-4-yl)] hydrazones . Egyptian Pharmaceutical Journal.
(2014). Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8 . Bioorganic Chemistry.
(2014). Synthesis Antimicrobial and Anticancer Activity of 1-[(arylalkylidene)amino]-3-(4H-1,2,4-triazol-4-yl)thiourea . JOURNAL OF PHARMACEUTICAL CHEMISTRY.
(2014). Anti-arthritic activity of ethanolic extract from the leaves of Commiphora caudata (Linn.) in complete Freund′s adjuvant-induced arthritic rats . Nigerian Journal of Experimental and Clinical Biosciences.
(2014). Effect of Atorvastatin on Pharmacology of Sitagliptin in Streptozotocin-Nicotinamide Induced Type-II Diabetes in Rats . Biology and Medicine.
Eggadi, V., Gundamedi, S., Sheshagiri, S.B.B., Revoori, S.K., Jupally, V.R., Kulandaivelu, U.(2014). Evaluation of anticancer activity of Annona muricata in 1, 2-dimethyl hydrazine induced Colon Cancer . World Applied Sciences Journal. 32. (3). p. 444-450.
Alagusundaram, M., Cherukupalli, C., Ramesh Reddy, K., Angala Parameswari, S., Umasankar, K., Jayachandrareddy, P.(2014). Design and characterization of mouth dissolving tablets of Metoprolol tartrate . International Journal of Research in Pharmaceutical Sciences. 5. (3). p. 159-170.
Alagusundaram, M., Raju, R., Ramesh Reddy, K., Angala Parameswari, S., Umasankar, K., Jayachandra Reddy, P.(2014). Formulation and in-vitro in-vivo characterization of buccoadhesive bilayer tablets of Carvedilol . International Journal of Research in Pharmaceutical Sciences. 5. (3). p. 178-187.
Kulandaivelu, U., Chilakamari, L.M., Jadav, S.S., Rao, T.R., Jayaveera, K.N., Shireesha, B., Hauser, A.-T., Senger, J., Marek, M., Romier, C., et al.(2014). Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8 . Bioorganic Chemistry. 57. p. 116-120.
(2013). A comprehensive review on SAR of curcumin . Mini reviews in medicinal chemistry.
(2013). Synthesis antimicrobial and anticancer activity of N′-arylmethylidene-piperazine-1-carbothiohydrazide . Medicinal Chemistry Research.
(2013). Screening of the Anticonvulsant Activity of Some Isatin Derivatives in Experimental Seizure Models and Its Effect on Brain GABA Levels in Mice . American Journal of Pharmacological Sciences.
(2013). Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity . Chemical Papers.
Kulandaivelu, U., Shireesha, B., Mahesh, C., Vidyasagar, J.V., Rao, T.R., Jayaveera, K.N., Saiko, P., Graser, G., Szekeres, T., Jayaprakash, V.(2013). Synthesis antimicrobial and anticancer activity of N′- arylmethylidene-piperazine-1-carbothiohydrazide . Medicinal Chemistry Research. 22. (6). p. 2802-2808.
Mahapatra, M., Kulandaivelu, U., Saiko, P., Graser, G., Szekeres, T., Andrei, G., Snoeck, R., Balzarini, J., Jayaprakash, V.(2013). Methyl-2-arylidene hydrazinecarbodithioates: Synthesis and biological activity . Chemical Papers. 67. (6). p. 650-656.
Bandaru, SS and Dileep, P and Vasudeva Murthy, S and Venkateshwarlu, E and Sharavana Bhava, BS and Umasankar, K and Venkateshwar Rao, J(2013). Efficacy of Oral Anti-Diabetic Agents for Glycaemic Control in Type-2 Diabetic Patients with Obesity. Journal of Pharmacy and Nutrition Sciences. 3. p. 141--8.
Venkateshwarlu, E and Sharavana Bhava, BS and Umasankar, K and Venkateshwar Rao, J(2013). Evaluation of diuretic activity of isatin derivatives in wistar rats. Journal of Pharmacy and Nutrition Sciences. 3. p. 141--8.
Venkateshwarlu, E., Sharvana Bhava, B.S., Umasankar, K., Venkateshwar Rao, J.(2013). Evaluation of diuretic activity of isatin derivatives in wistar rats . Journal of Pharmacy and Nutrition Sciences. 3. (2). p. 141-148.
Subrahmanyam, B.S., Bhava, B.S.S., Venkateshwarlu, E., Umasankar, K., Dileep, P., Murthy, S.V.(2013). Efficacy of oral anti-diabetic agents for glycaemic control in type-2 diabetic patients with obesity . Global Journal of Pharmacology. 7. (3). p. 311-315.
Umasankar, K., Nambikkairaj, B., Manley Backyavathy, D.(2013). Wound healing activity of topical Mentha piperita and Cymbopogan citratus essential oil on streptozotocin induced rats . Asian Journal of Pharmaceutical and Clinical Research. 6. (3). p. 180-183.
Venkatesh, E., Aparna, C., Umasankar, K., Jayachandra Reddy, P., Prabhakaran, V.(2013). Resealed erythrocytes: A novel approach to treat chronic diseases . International Journal of Pharmaceutical Sciences Review and Research. 23. (2). p. 298-306.
Rajasekhar Reddy, A., Dinesh, P., Prabhakar, A.S., Umasankar, K., Shireesha, B., Raju, M.B.(2013). A comprehensive review on SAR of curcumin . Mini-Reviews in Medicinal Chemistry. 13. (12). p. 1769-1777.
(2012). In silico evaluation of TERT inhibition by anticancer drugs . Journal of Molecular Modeling.
(2012). 2D-QSAR Studies of Tacrine Analogues for Acetylcholine Esterase (AChE) Inhibition using Multiple Linear Regression Analysis . Letters in Drug Design & Discovery.
Umasankar, K., Nambikkairaj, B., Manley Backyavathy, D.(2012). Effect of topical treatment of rosmarinus officinalis essential oil on wound healing in streptozotocin induced diabetic rats . Nature Environment and Pollution Technology. 11. (4). p. 607-611.
Venkateshwarlu, E., Venkateshwar Rao, J., Umasankar, K., Dheeraj, G.(2012). Study of anti-inflammatory, analgesic and antipyretic activity of novel Isatin derivatives . Asian Journal of Pharmaceutical and Clinical Research. 5. (4). p. 187-190.
Mahendar, P., Sirisha, K., Kulandaivelu, U., Shankar, P.L.J., Radhika, T., Sadanandam, A.(2012). In silico evaluation of TERT inhibition by anticancer drugs . Journal of Molecular Modeling. 18. (10). p. 4739-4744.
Achanta, P.S., Alavala, R.R., Kulandaivelu, U., Boyapati, S., Ingale, K.(2012). 2D-QSAR studies of tacrine analogues for acetylcholine esterase (AChE) inhibition using multiple linear regression analysis . Letters in Drug Design and Discovery. 9. (9). p. 858-866.
Pore, D., Alli, R., Prabhakar, A.S.C., Alavala, R.R., Kulandaivelu, U., Boyapati, S.(2012). Solid-phase microwave assisted synthesis of curcumin analogs . Letters in Organic Chemistry. 9. (6). p. 447-450.
(2011). Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors . Bioorganic & Medicinal Chemistry.
(2011). Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors . Bioorganic & Medicinal Chemistry.
(2011). Synthesis, Antimicrobial and Anticancer Activity of New Thiosemicarbazone Derivatives . Archiv der Pharmazie.
Sirisha, K., Shekhar, M.C., Umasankar, K., Mahendar, P., Sadanandam, A., Achaiah, G., Reddy, V.M.(2011). Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors . Bioorganic and Medicinal Chemistry. 19. (10). p. 3249-3254.
Kulandaivelu, U., Padmini, V.G., Suneetha, K., Shireesha, B., Vidyasagar, J.V., Rao, T.R., Jayaveera, K.N., Basu, A., Jayaprakash, V.(2011). Synthesis, antimicrobial and anticancer activity of new thiosemicarbazone derivatives . Archiv der Pharmazie. 344. (2). p. 84-90.
(2010). Synthesis, Antimicrobial Evaluation, and Docking Studies of Novel 4-Substituted Quinazoline Derivatives as DNA-Gyrase Inhibitors . Archiv der Pharmazie.
(2010). Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies . Bioorganic & Medicinal Chemistry.
Karuppasamy, M., Mahapatra, M., Yabanoglu, S., Ucar, G., Sinha, B.N., Basu, A., Mishra, N., Sharon, A., Kulandaivelu, U., Jayaprakash, V.(2010). Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies . Bioorganic and Medicinal Chemistry. 18. (5). p. 1875-1881.
Umasankar, K., Uma Maheswara Reddy, C.(2010). Nanoparticular drug delivery system of anticancer drug - Flutamide . International Journal of PharmTech Research. 2. (2). p. 1155-1159.
Boyapati, S., Kulandaivelu, U., Sangu, S., Vanga, M.R.(2010). Synthesis, antimicrobial evaluation, and docking studies of novel 4-substituted quinazoline derivatives as DNA-gyrase inhibitors . Archiv der Pharmazie. 343. (10). p. 570-576.
Muthukumar Karuppasamy, Manojkumar Mahapatra, Samiye Yabanoglu, Gulberk Ucar, Barij Nayan Sinha, Arijit Basu, Nibha Mishra, Ashoke Sharon, Umasankar Kulandaivelu, Venkatesan Jayaprakash, 2010, 'Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies', <i>Bioorganic &amp; Medicinal Chemistry</i>, vol. 18, no. 5, pp. 1875-1881 .
Shireesha Boyapati, Umasankar Kulandaivelu, Srinivas Sangu, Malla Reddy Vanga, 2010, 'Synthesis, Antimicrobial Evaluation, and Docking Studies of Novel 4-Substituted Quinazoline Derivatives as DNA-Gyrase Inhibitors', <i>Archiv der Pharmazie</i>, vol. 343, no. 10, pp. 570-576 .
Umasankar Kulandaivelu, Valisakka Gari Padmini, Kyatham Suneetha, Boyapati Shireesha, Jannu Vincent Vidyasagar, Tadikonda Rama Rao, Jayaveera K N, Arijit Basu, Venkatesan Jayaprakash, 2011, 'Synthesis, Antimicrobial and Anticancer Activity of New Thiosemicarbazone Derivatives', <i>Archiv der Pharmazie</i>, vol. 344, no. 2, pp. 84-90 .
Shireesha Boyapati, Umasankar Kulandaivelu, Srinivas Sangu, Malla Reddy Vanga, 2011, 'ChemInform Abstract: Synthesis, Antimicrobial Evaluation, and Docking Studies of Novel 4-Substituted Quinazoline Derivatives as DNA-Gyrase Inhibitors.', <i>ChemInform</i>, vol. 42, no. 9, pp. no-no .
Kalam Sirisha, Maddela Chandra Shekhar, Kulandaivelu Umasankar, Porika Mahendar, Abbagani Sadanandam, Garlapati Achaiah, Vanga Malla Reddy, 2011, 'Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors', <i>Bioorganic &amp; Medicinal Chemistry</i>, vol. 19, no. 10, pp. 3249-3254 .
Prabhakar S. Achanta, Rajasekhar Reddy Alavala, Umasankar Kulandaivelu, Shireesha Boyapati, Kundan Ingale, 2012, '2D-QSAR Studies of Tacrine Analogues for Acetylcholine Esterase (AChE) Inhibition using Multiple Linear Regression Analysis', <i>Letters in Drug Design &amp; Discovery</i>, vol. 9, no. 9 .
Manojkumar Mahapatra, Umasankar Kulandaivelu, Philipp Saiko, Geraldine Graser, Thomas Szekeres, Graciela Andrei, Robert Snoeck, Jan Balzarini, Venkatesan Jayaprakash, 2013, 'Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity', <i>Chemical Papers</i>, vol. 19 .
Umasankar Kulandaivelu, Boyapati Shireesha, Chidara Mahesh, Jannu Vincent Vidyasagar, Tadikonda Rama Rao, K. N. Jayaveera, Philipp Saiko, Geraldine Graser, Thomas Szekeres, Venkatesan Jayaprakash, 2012, 'Synthesis antimicrobial and anticancer activity of N′-arylmethylidene-piperazine-1-carbothiohydrazide', <i>Medicinal Chemistry Research</i>, vol. 13, no. 2 .
Porika Mahendar, Kalam Sirisha, Umasankar Kulandaivelu, Prakhya Laxmi Jaya Shankar, Tippani Radhika, Abbagani Sadanandam, 2012, 'In silico evaluation of TERT inhibition by anticancer drugs', <i>Journal of Molecular Modeling</i>, vol. 18, no. 10 .
Dinesh Pore, Ramesh Alli, Achanta S.C. Prabhakar, Rajashekar R. Alavala, Umasankar Kulandaivelu, Shireesha Boyapati, 2012, 'Solid-Phase Microwave Assisted Synthesis of Curcumin Analogs', <i>Letters in Organic Chemistry</i>, vol. 9, no. 6 .
JOURNAL ISSUE
(2019). IN-VITRO ANTIOXIDANT PROPERTIES OF DELONIX ELATA WHOLE PLANT EXTRACTS . INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH.
(2019). IN-VITRO ANTIOXIDANT PROPERTIES OF DELONIX ELATA WHOLE PLANT EXTRACTS . INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH.