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Hire Dr. Syed ibad H.

Pakistan

USD 25 /hr

Freelance researcher & meta-analysis expert in Revman and metaXL Medical writer with 2 years of experience in research

Profile Summary

I'm a medical researcher, currently a MBBS candidate, at Jinnah Sindh Medical University, Karachi, specializing in evidence synthesis — systematic reviews, meta-analyses, and observational database studies. I've contributed to 22 publications spanning cardiology, gastroenterology, nephrology, oncology, and neurology, including work published in Annals of Pharmacotherapy, BMC Cardiovascular Disorders, Journal of Cardiovascular Pharmacology, and presented at AHA, ASH, and ACG annual meetings. What I do: I run the full evidence-synthesis pipeline end-to-end — from formulating the research question and search strategy through data extraction, statistical pooling, and reporting. I'm comfortable both leading a project from topic selection to submission and slotting into an existing team to handle the analysis/methodology piece. Technical skills: RevMan, MetaXL, SPSS, and Excel for data analysis; GRADEpro GDT for certainty-of-evidence assessment; Cochrane RoB 1/RoB 2 for risk-of-bias evaluation; and Trial Sequential Analysis (TSA) for assessing the robustness of cumulative meta-analytic evidence. Certified in SPSS (RCOP, Level 1) and in Systematic Review & Meta-Analysis methodology (Research Nexus, June 2024), including dedicated RevMan and GRADE training. Project experience: My work includes RCT meta-analyses (e.g., oral PCSK9 inhibitors for hypercholesterolemia, pioglitazone add-on therapy in type 2 diabetes, pitolisant for narcolepsy/OSA — first-authored), diagnostic accuracy reviews with GRADE assessment (transperineal vs. transrectal prostate biopsy), and large-scale U.S. mortality-trend analyses using CDC WONDER data (chronic kidney disease/VTE, renal failure/pulmonary hypertension). I've also written letters to the editor, cross-sectional studies, and narrative reviews, and co-registered projects with PROSPERO. What I can help with: protocol design and PROSPERO registration, literature search and screening, data extraction, statistical analysis in RevMan/MetaXL/SPSS, RoB and GRADE assessments, Trial Sequential Analysis, and manuscript preparation through to journal submission.

Subject Matter Expertise

• ☆ Biostatistics
• ☆ Data Analysis
• ☆ Big Data Analytics
• ☆ Text Mining & Analytics
• ☆ SPSS
• ☆ Clinical Trials
• ☆ IRB Applications
• ☆ Clinical Trial Design
• ☆ Clinical Data Management
• ☆ Clinical Trials Data Analysis
• ☆ Cardiovascular Disease
• ☆ Vascular Medicine
• ☆ Pacemakers
• ☆ Clinical Cardiac Electrophysiology
• ☆ Interventional Cardiology
• ☆ Cardiovascular Disease Management

Services

• Writing
• Research
• Data & AI

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Business & Legal Writing, Copywriting, Creative Writing

Research Meta-Research, Feasibility Study, Systematic Literature Review

Data & AI Statistical Analysis

Work Experience

student

Jinnah Sindh Medical University

February 2023 - Present

Education

MBBS

Jinnah Sindh Medical University

February 2023 - Present

Certifications

• RCOP level 1

  Research Council of Pakistan

  January 2024 - Present

Publications

JOURNAL ARTICLE

Syed Ibad Hussain, Rabia Nizam, Amna Amir Jalal, Zahabia Adnan, Zainab Mehmood, Fatima Sohail, Muhammad Hanif Khan (2026). Sequential 5-fluorouracil–photodynamic therapy: A mechanism-based approach to actinic keratosis . Photodiagnosis and Photodynamic Therapy.

Syed Ibad Hussain, Allahdad Khan, Zahid Ullah, Maheen Sheraz, Huzaifa Noor, Umama Alam, Eaman Fatima, Mohammed Saifuddin, Farzana Kousar, Mohamed Antar, et al. (2026). Disparity trends in coexisting renal failure- and pulmonary hypertension-related mortality in the United States (1999–2020): CDC WONDER database study . Annals of Medicine & Surgery.

Syed Ibad Hussain, Amna Amir Jalal, Shaikh Muhammad Daniyal, Zainab Arif, Erum Siddiqui, Fatima Qazi, Muhammad Burhan (2026). Efficacy and Safety of Oral PCSK9 Inhibitors in Adults With Hypercholesterolemia: An Updated Systematic Review and Meta-Analysis of RCTs . Annals of Pharmacotherapy.

Syed Ibad Hussain, Amna Amir Jalal, Erum Siddiqui, Muhammad Saad Khan, Muhammad Burhan, Ali Jawwad Karim, Rabia Nizam, Mahrukh Amir (2026). Efficacy and Safety of Oral PCSK9 Inhibitors in Adults With Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials . Journal of Cardiovascular Pharmacology.

Syed Ibad Hussain, Amna Amir Jalal, Muhammad Saad Khan, Erum Siddiqui, Harshika Khaim Chandani, Ali Jawwad Karim, Shanza Shakir (2026). Efficacy and Safety of Pitolisant for Excessive Daytime Sleepiness in Narcolepsy and Obstructive Sleep Apnea: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials . Annals of Pharmacotherapy.

Syed Ibad Hussain, Shamikha Cheema, Arun Kumar Maloth, Momina Khaliq, Muhammad Qasim, Muhammad Faique Hassan, Muhammad Shaheer Bin Faheem, Hassan Ijaz, Vicky Kumar (2026). Who Bears the Brunt? Geographic, racial and ethnic disparities in mortality trends of inflammatory bowel disorders in the United States . Journal of Clinical and Translational Science.

Adnan, Z., Hussain, S. I., Jalal, A. A., Shaukat, A., Abid, E., Burhan, M., Ahmed, A., Saghir, E., Daniyal, S. M., Shakir, S., Samadi, A., & Raza, A. A. (2026). Rivaroxaban versus Low Molecular Weight Heparin for Cancer-Associated Venous Thromboembolism: A Systematic Review and Meta-Analysis. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 32, 10760296261459711. https://doi.org/10.1177/10760296261459711 .

Syed Ibad Hussain, Amna Amir Jalal, Erum Siddiqui, Muhammad Saad Khan, Muhammad Burhan, Ali Jawwad Karim, Rabia Nizam, Mahrukh Amir (2025). Efficacy and Safety of Oral PCSK9 Inhibitors in Adults with Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials . Journal of Cardiovascular Pharmacology.

Syed Ibad Hussain, Amna Amir Jalal, Zain Ul Abideen, Erum Siddiqui, Shaikh Muhammad Daniyal, Arsalan Ahmed, Abdullah Hameed, Shanza Shakir, Humna Minhas, Eisha Abid, et al. (2025). Diagnostic accuracy and safety of image-guided transperineal versus transrectal prostate biopsy for clinically significant prostate cancer: a GRADE-assessed systematic review and meta-analysis . Future Oncology.

Syed Ibad Hussain, Amna Amir Jalal, Muhammad Saad Khan, Erum Siddiqui, Harshika Khaim Chandani, Ali Jawwad Karim, Shanza Shakir (2025). Efficacy and Safety of Pitolisant for Excessive Daytime Sleepiness in Narcolepsy and Obstructive Sleep Apnea: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials . Annals of Pharmacotherapy.

Syed Ibad Hussain, Shamikha Cheema, Muhammad Shaheer Bin Faheem, Amna Amir Jalal, Mohamed Rifai, Areej Dar, Muhammad Burhan, Areeba Shahid, Muhammad Seerat Ali, Amna Anwar, et al. (2025). Toxic heavy metal exposure and heart health: a systematic review and meta-analysis of 324,331 patients . BMC Cardiovascular Disorders.

Syed ibad Hussain, Shamikha Cheema, FNU Naintara, Areej Dar, Esha Tanveer, Areeba Shahid, Mohamed Rifai, Amna Anwar, Amna Jalal, Muhammad Burhan, et al. (2025). Abstract 4365174: Toxic Heavy Metal Exposure and Heart Health: A Systematic Review and Meta-analysis of 324,331 Patients . Circulation.

Syed ibad Hussain, Elangovan Krishnan, Ashna Habib, Umar Qureshi, Jansi Sethuraj, Kavin Elangovan, Ramya Elangovan, Mohamad Amro Alrouh, ALAN OSWALD FRANKLIN JOHNSON, Tirth Patel, et al. (2025). Abstract 4371736: Residual Learning Networks for Automated Detection of Hypertensive Retinopathy: A Multi-Institutional Validation Study . Circulation.

Amna Amjad, Abdullah Bin Usman, Nayanika Tummala, Shalin Rawal, Muhammad Ibrahim, Maryam Sial, Arooba Usman, Syed Hussain, Rabiah Aslam Ansari, Arun Kumar Maloth, et al. (2025). Mortality trends in patients with co-occurring chronic kidney disease and venous thromboembolism in the United States: A 25-year CDC wonder analysis (1999–2023) . Blood.

Amir Jalal, A., Ibad Hussain, S., Shahzad, M., Shariq Hasan, S., & Shahzad, F. (2025). Crohn’s disease in Pakistan, a low-income country perspective: difficulty in differential diagnosis and treatment availability. Journal of the Pakistan Medical Association, 75(10), 1679–1680. https://doi.org/10.47391/JPMA.30148 .

Syed Ibad Hussain, Shamikha Cheema, Aria Khan, Momina Khaliq, Arun Kumar Maloth, Muhammad Shaheer Bin Faheem, Muhammad Faique Hassan, Hassan Ijaz (2025). S1962 Who Bears the Brunt? Geographic, Racial, and Ethnic Disparities in Inflammatory Bowel Disease in the United States . American Journal of Gastroenterology.

Syed Ibad Hussain, Rabia Nizam, Amna Amir Jalal (2025). Letter to the editor: increased incidence of blood culture contaminations during and after the COVID-19 pandemic . Infection.

Dr. Sofia Daudpota,Dr. Nighat Shah,Dr. Syeda Aliza Aftab,Dr. Rashid Ali Daudpota,Syed Ibad Hussain,Dr. Jaazba Qamar(2025). PREGNANCY OUTCOME IN PATIENTS WITH CONNECTIVE TISSUE DISEASE (CTD) IN A TERTIARY CARE HOSPITAL . Zenodo. Zenodo

Eisha Abid, Areeba Abid, Hiba Abid, Syed Ibad Hussain, Amna Amir Jalal (2025). Strengthening Predictive Models and Risk Assessment in Autoimmune Gastritis: A Critical Appraisal . Journal of Gastroenterology and Hepatology.

Hala Najeeb, Muhammad Aamir, Syed I. Hussain, Amna A. Jalal, Azhar H. Qureshi, Amisha Kumari, Dheeraj K. Sailish, Tisha Motwani (2025). C-18 | Efficacy of Vitamin D Supplementation on Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting: An Updated Meta-Analysis of Randomized Controlled Trials . Journal of the Society for Cardiovascular Angiography & Interventions.

Syed Ibad Hussain, Matia Fawad Memon, Zauha Fawad Memon, Sibgha Fawad Memon (2025). Selective factor B inhibition with iptacopan: transforming C3 glomerulopathy management . International Urology and Nephrology.

PREPRINT

Amna Amir Jalal, Syed Ibad Hussain, Erum Siddiqui, et al. Efficacy and Safety of Oral PCSK9 Inhibitors in Adults with Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Authorea. October 09, 2025 .

CONFERENCE PRESENTATION

Tummala, Nayanika MD*; Wazir, Hakim MBBS; Nimmagadda, Rithish MBBS; Amir Jalal, Amna MBBS; Nasar, Muhammad Haleem MBBS; Muzzafar, Maryam MBBS; Hussain, Syed Ibad MBBS; Boppana, Kusalik MBBS; Chilakapati, Ashish MBBS; Sohi, Gurmanleen Singh MBBS; Rathi, Diya MBBS; Inam, Noora MBBS. S1932 Microbiota-Targeted Therapies in Biologic-Refractory Ulcerative Colitis: A Systematic Review and Meta-Analysis. The American Journal of Gastroenterology 120(10S2):p S415, October 2025. | DOI: 10.14309/01.ajg.0001135188.64264.51 .