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Life sciences strategist | 30+ years in stem cells & biomaterials, higher education leadership, R&D commercialisation

Profile Summary

I am a life sciences consultant with over 30 years’ experience in stem cells, biomaterials, regenerative medicine, and tertiary education leadership. I have founded and led biotech ventures, developing expertise in intellectual property, investment, and commercialisation strategies for advanced biomaterials. My consulting experience spans wet lab design, experimental strategy, medical approval processes, and specialised fields including stem cell biology, fertility, and materials science. I work with universities, start-ups, and investors to bridge research and industry, helping to secure funding, streamline R&D pathways, and translate innovation into real-world products and impact.

Subject Matter Expertise

• ☆ Developmental Biology
• ☆ Embryology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Microarrays
• ☆ Recombinant DNA
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Comparative Physiology
• ☆ Histology
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Nanobiotechnology
• ☆ Biomedical Engineering
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Plasma Physics
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Surface Receptors
• ☆ Chemical Biology
• ☆ Immunohistochemistry
• ☆ Tissue Engineering
• ☆ Cytometry
• ☆ In vitro Diagnostics
• ☆ In vitro Diagnostic Design
• ☆ Point-of-Care Devices
• ☆ Medical Sciences
• ☆ Product Evaluation
• ☆ Material Sourcing
• ☆ Product Validation
• ☆ Concept Development
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Feasibility Studies
• ☆ Technology Scouting
• ☆ Fact Checking
• ☆ Literature Search
• ☆ Gap Analysis
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Case Studies
• ☆ Textbook Content Writing
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review

Services

• Writing
• Research
• Consulting
• Product Development

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, General Proofreading & Editing

Research Technology Scouting, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Business Strategy Consulting, Go-to-Market Strategy Consulting, Scientific and Technical Consulting

Product Development Product Validation, Manufacturing, Concept Development, Product Launch Support, Prototyping

Work Experience

Scientific Director

Quoll Biosciences

March 2025 - Present

CEO, Founder

Culturon Pty Ltd

March 2022 - Present

Founder/ Principal consultant

Stuart Fraser Consulting

January 2021 - Present

Associate Professor

The University of Sydney,Australia

March 2010 - February 2021

ASSISTANT PROFESSOR

Mount Sinai School of Medicine, NYC

February 2004 - March 2010

Postdoctoral Fellow

Johannes Gutenberg University Mainz

April 2002 - February 2004

Postdoctoral Fellow

Kyoto University

March 1998 - March 2002

Education

PhD

The University of Hong Kong

February 1993 - January 1998

B.Sc (Honours)

Monash University

February 1988 - December 1992

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Laura Libnan Haidar, Yuheng Wang, Aaron D. Gilmour, Elmer Austria, Badwi B. Boumelhem, Naveed Aziz Khan, Arifah Anwar Fadzil, Stuart T. Fraser, Marcela M. M. Bilek, Behnam Akhavan (2025). Direct covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications . Journal of Materials Chemistry B.

Badwi B. Boumelhem, Stuart T. Fraser, Syamak Farajikhah, Rachel A. Shparberg, Michael B. Morris, Marcela M.M. Bilek, Anyu Zhang, Behnam Akhavan, Simon Fleming, Maryanne Large (2024). Modelling the development of biological structures displaying longitudinal geometries in vitro: culturing pluripotent stem cells on plasma-treated, growth factor-coupled polycaprolactone fibres . Engineered Regeneration.

Clara T. H. Tran, Aaron D. Gilmour, Badwi B. Boumelhem, Stuart T. Fraser, Marcela M. M. Bilek (2024). Plasma‐Activated Coated Glass: A Novel Platform for Optimal Optical Performance and Cell Culture Substrate Customization . Small Science.

Stuart Fraser, Fathima Shihana, Pradeep Manuneedhi Cholan, Stefan&#160;H. Oehlers, Devanshi Seth (2023). Investigating the role of lipid genes in liver disease using fatty liver models of alcohol and high fat in zebrafish (<i>Danio rerio</i>) . Liver International.

Stuart Fraser, Serena Li, Ginell Ranpura, Seakcheng Lim, Emma S. Singer, Jeremy D.K. Parker, Joshua Crowe, Richard D. Bagnall, Zachary Laksman, Christopher Semsarian (2023). Generation of an induced pluripotent stem cell line from a patient with conduction disease and recurrent ventricular fibrillation with a sodium voltage-gated channel alpha subunit 5 (SCN5A) gene c.392 + 3A &gt; G splice-site variant . Stem Cell Research.

Laura L. Haidar, Mark Baldry, Stuart T. Fraser, Badwi Bob Boumelhem, Aaron D. Gilmour, Zongwen Liu, Zhong Zheng, Marcela M. M. Bilek, Behnam Akhavan (2022). Surface-Active Plasma-Polymerized Nanoparticles for Multifunctional Diagnostic, Targeting, and Therapeutic Probes . ACS Applied Nano Materials.

Badwi B. Boumelhem, Chelsea Pilgrim, Vincent E. Zwicker, Jacek L. Kolanowski, Jia Hao Yeo, Katrina A. Jolliffe, Elizabeth J. New, Margot L. Day, Stephen J. Assinder, Stuart T. Fraser(2022). Intracellular flow cytometric lipid analysis – a multiparametric system to assess distinct lipid classes in live cells . Journal of Cell Science. 135. (5). The Company of Biologists

Syamak Farajikhah, Antoine F. J. Runge, Badwi B. Boumelhem, Ivan D. Rukhlenko, Alessio Stefani, Sepidar Sayyar, Peter C. Innis, Stuart T. Fraser, Simon Fleming, Maryanne C. J. Large (2021). Thermally drawn biodegradable fibers with tailored topography for biomedical applications . Journal of Biomedical Materials Research Part B: Applied Biomaterials.

Stuart T. Fraser(2020). A new frontier: developing an undergraduate assessment task aimed at improving the representation of biomedical scientific information on Wikipedia . Studies in Higher Education. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--12. Informa {UK} Limited

Jia Hao Yeo, Yun Wah Lam, Stuart T. Fraser(2019). Cellular dynamics of mammalian red blood cell production in the erythroblastic island niche . Biophysical Reviews. 11. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 873--894. Springer Science and Business Media {LLC}

Zwicker VE, Oliveira BL, Yeo JH, Fraser ST, Bernardes GJL, New EJ, Jolliffe KA(2018). A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism . Angewandte Chemie (International ed. in English).

Yeo JH, Colonne CK, Tasneem N, Cosgriff MP, Fraser ST(2018). The iron islands: Erythroblastic islands and iron metabolism . Biochimica et biophysica acta. General subjects.

Yeo JH, Cosgriff MP, Fraser ST(2018). Analyzing the Formation, Morphology, and Integrity of Erythroblastic Islands . Methods in molecular biology (Clifton, N.J.).

McKenzie CV, Colonne CK, Yeo JH, Fraser ST(2017). Splenomegaly: Pathophysiological bases and therapeutic options . The international journal of biochemistry & cell biology.

(2017). Induced Pluripotent Stem Cell Technology and, Inherited Arrhythmia Syndromes . Heart rhythm.

(2017). A Carborane-Containing Fluorophore as a Stain of Cellular Lipid Droplets . Chemistry, an Asian journal.

(2017). Flow cytometric single cell analysis reveals heterogeneity between adipose depots . Adipocyte.

(2017). Generation of induced pluripotent stem cells (iPSCs) from a hypertrophic cardiomyopathy patient with the pathogenic variant p.Val698Ala in beta-myosin heavy chain (MYH7) gene . Stem cell research.

(2017). Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy . Stem cell research.

(2017). Regulation of the embryonic erythropoietic niche: a future perspective . Blood research.

(2016). Induced pluripotent stem cells in the inherited cardiomyopathies: From disease mechanisms to novel therapies . Trends in cardiovascular medicine.

(2016). Studies of Hematopoietic Cell Differentiation with a Ratiometric and Reversible Sensor of Mitochondrial Reactive Oxygen Species . Antioxidants & redox signaling.

(2016). Scanning Electron Microscopy Reveals Two Distinct Classes of Erythroblastic Island Isolated from Adult Mammalian Bone Marrow . Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada.

Jia Hao Yeo, Bronwyn M. McAllan, Stuart T. Fraser(2016). Scanning Electron Microscopy Reveals Two Distinct Classes of Erythroblastic Island Isolated from Adult Mammalian Bone Marrow . Microscopy and Microanalysis. 22. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 368--378. Cambridge University Press ({CUP})

(2015). Host origin determines pH tolerance of Tritrichomonas foetus isolates from the feline gastrointestinal and bovine urogenital tracts . Experimental parasitology.

(2015). Mitochondrially targeted redox probe reveals the variations in oxidative capacity of the haematopoietic cells . Organic & biomolecular chemistry.

et al.(2015). Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice . Haematologica.

(2015). Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro . Human reproduction (Oxford, England).

(2015). Making Blood: The Haematopoietic Niche throughout Ontogeny . Stem cells international.

(2014). Gastrokine-2 is transiently expressed in the endodermal and endothelial cells of the maturing mouse yolk sac . Gene expression patterns : GEP.

(2014). Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm . Stem cells (Dayton, Ohio).

et al.(2014). Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells . PloS one.

(2013). Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice . Genesis (New York, N.Y. : 2000).

(2013). The modern primitives: applying new technological approaches to explore the biology of the earliest red blood cells . ISRN hematology.

Antas, V.I.(2013). Hemogenic endothelium: A vessel for blood production . International Journal of Biochemistry and Cell Biology. 45. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 692-695.

Guiu, J.(2013). Hes repressors are essential regulators of hematopoietic stem cell development downstream of notch signaling . Journal of Experimental Medicine. 210. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 71-84.

(2013). Rapid detection of haemotropic mycoplasma infection of feline erythrocytes using a novel flow cytometric approach . Parasites & vectors.

Wee, N.K.Y.(2013). The mammalian copper transporters CTR1 and CTR2 and their roles in development and disease . International Journal of Biochemistry and Cell Biology. 45. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 960-963.

Mizuochi, C.(2012). Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis . PLoS ONE. 7. (4).

Isern, J.(2012). Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo (Blood (2011) 117, (18) (4924-4934)) . Blood. 120. (24).

Funnell, A.P.W.(2012). The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo . Molecular and Cellular Biology. 32. (16). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3281-3292.

Baron, M.H.(2012). The embryonic origins of erythropoiesis in mammals . Blood. 119. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4828-4837.

Sugiyama, D.(2011). Embryonic regulation of the mouse hematopoietic niche . TheScientificWorldJournal. 11. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1770-1780.

Fraser, S.T.(2011). Heme oxygenase-1: A critical link between iron metabolism, erythropoiesis, and development . Advances in Hematology. 2011.

Isern, J.(2011). Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo . Blood. 117. (18). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4924-4934.

Isern, J.(2010). Developmental niches for embryonic erythroid cells . Blood Cells, Molecules, and Diseases. 44. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 207-208.

Isern, J.(2010). Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf . Blood. 116. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3972-3980.

Fraser, S.T.(2010). Use of transgenic fluorescent reporter mouse lines to monitor hematopoietic and erythroid development during embryogenesis . Methods in Enzymology. 476. (C). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 403-427.

Zhang, H.(2009). Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells . Stem Cells. 27. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2884-2895.

Fraser, S.T.(2009). Embryonic fates for extraembryonic lineages: New perspectives . Journal of Cellular Biochemistry. 107. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 586-591.

Isern, J.(2008). The fetal liver is a niche for maturation of primitive erythroid cells . Proceedings of the National Academy of Sciences of the United States of America. 105. (18). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6662-6667.

Fraser, S.T.(2007). Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression . Blood. 109. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 343-352.

Roos, W.P.(2007). Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O6-methylguanine due to high E2F1 regulated mismatch repair . Cell Death and Differentiation. 14. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1422-1432.

Haremaki, T.(2007). Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation . Proceedings of the National Academy of Sciences of the United States of America. 104. (29). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 12029-12034.

Willey, S.(2006). Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor . Blood. 107. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3122-3130.

Kwon, G.S.(2006). Tg(Afp-GFP) expression marks primitive and definitive endoderm lineages during mouse development . Developmental Dynamics. 235. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2549-2558.

Baron, M.H.(2005). The specification of early hematopoiesis in the mammal . Current Opinion in Hematology. 12. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 217-221.

Fraser, S.T.(2005). Using a histone yellow fluorescent protein fusion for tagging and tracking endothelial cells in ES cells and mice . Genesis. 42. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 162-171.

Snyder, A.(2004). Bone morphogenetic proteins in vertebrate hematopoietic development . Journal of Cellular Biochemistry. 93. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 224-232.

Weston, J.A.(2004). Neural Crest and the Origin of Ectomesenchyme: Neural Fold Heterogeneity Suggests an Alternative Hypothesis . Developmental Dynamics. 229. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 118-130.

Fraser, S.T.(2003). In Vitro Differentiation of Mouse Embryonic Stem Cells: Hematopoietic and Vascular Cell Types . Methods in Enzymology. 365. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 59-72.

Bockamp, E.(2003). Of mice and models: Improved animal models for biomedical research . Physiological Genomics. 11. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 115-132.

Fraser, S.T.(2003). Putative intermediate precursor between hematogenic endothelial cells and blood cells in the developing embryo . Development Growth and Differentiation. 45. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 63-75.

Schroeder, T.(2003). Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis . Proceedings of the National Academy of Sciences of the United States of America. 100. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4018-4023.

Fraser, S.T.(2002). Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin+ population . Experimental Hematology. 30. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1070-1078.

Fraser, S.T.(2002). Embryonic stem cell differentiation as a model to study hematopoietic and endothelial cell development . Methods in molecular biology (Clifton, N.J.). 185. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 71-81.

Fraser, S.(2002). Realistic attitude takes postdocs a long way [2] . Nature. 419. (6910). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 877-878.

Hashi, H.(2001). Compartmentalization of Peyer's patch anlagen before lymphocyte entry . Journal of Immunology. 166. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3702-3709.

Ogawa, M.(2001). Origin of hematopoietic progenitors during embryogenesis . International Reviews of Immunology. 20. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 21-44.

Yokomizo, T.(2001). Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells . Genes to Cells. 6. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13-23.

Nishikawa, S.-I.(2000). All B cells are progeny of endothelial cells: A new perspective . Immunological Reviews. 175. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 112-119.

Nishikawa, S.-I.(2000). Inflammation, a prototype for organogenesis of the lymphopoietic/hematopoietic system . Current Opinion in Immunology. 12. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 342-345.

Berzins, S.P.(1999). Thymic shared antigen-2: A novel cell surface marker associated with T cell differentiation and activation . Journal of Immunology. 162. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5119-5126.

Stuart T. Fraser, Margaret H. Baron, 2009, 'Embryonic fates for extraembryonic lineages: New perspectives', <i>Journal of Cellular Biochemistry</i>, vol. 107, no. 4, pp. 586-591 .

Stuart Fraser, 2002, 'Realistic attitude takes postdocs a long way', <i>Nature</i>, vol. 419, no. 6910, pp. 877-878 .