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Hire Dr. Stephanie J.

Profile Summary

I have had for many years, a deep interest in the complexity and sophistication that underpins the cellular functions vital for life. In particular, I have a great love of protein interaction networks with my DPhil thesis, “The Investigation of the OS-9/Grp94 interaction and its role in Endoplasmic Reticulum Associated Degradation (ERAD)”, focusing on quality control within the ER, namely the recognition and subsequent degradation of misfolded proteins. In particular, I focused on the mapping of protein interactions through the generation of tagged truncated and/or mutated constructs, their transfection into mammalian cell culture and the subsequent isolation of interaction complexes through co-precipitation with analysis via SDS-PAGE/immunoblotting. These results were complimented by experiments employing immunofluorescence, shRNA and through the generation/purification of recombinant proteins, with the resultant data published in Molecular Biology of the Cell in a paper titled: “OS-9 Facilitates Turnover of Non-native GRP94 Marked by Hyper-glycosylation”. In addition to standard problem solving, my DPhil also provided the trials and experience of establishing a lab from the ground up. As the sole member of a new lab, I was confronted with a steep learning curve with the initiative and interpersonal skills required to seek out help and advice a necessity. In addition to my scientific experience, I reveal in organisational and team based challenges. I have been deeply involved in the Merton College Middle Common Room (MCR) Oxford, acting in four committee positions including President (2011-2012), a role which entailed leadership, representation, negotiations and ensuring productive relationships both internally (between fellows and staff) and externally (between the university, colleges and alumni). An additional ability which I acquired at Oxford, that I am particularly passionate about, is rowing. It requires extreme commitment, a high level of motivation and it is, in my opinion the ultimate team sport. From a complete novice, I dedicated myself to the hard work required to successfully race as a member of the Oxford University Women’s Boat Club, successfully defeating Cambridge (Osiris, 2012) and subsequently acting as Vice-President (2013). Juggling of academia, rowing and the MCR committee ensured I gained a very wide ranging skill set, including extreme time management, establishing links with sponsors, logistics of large and small event management, people management and conflict resolution within a team.

Subject Matter Expertise

• ☆ Separation & Purification
• ☆ Molecular Imaging
• ☆ Biology/Life Sciences
• ☆ Microbiology
• ☆ Virology
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Mutagenesis
• ☆ Recombinant Protein Expression
• ☆ Nanobiotechnology
• ☆ Chaos Theory
• ☆ Cell Culture
• ☆ Protein/Enzyme Engineering
• ☆ Leadership
• ☆ Event Planning
• ☆ Science Education
• ☆ Choral & Vocal Music
• ☆ Medical Sciences
• ☆ Technical & Scientific Writing

Services

• Writing
• Consulting
• Product Development

Work Experience

Research Assistant

University of Oxford

November 2014 - Present

Research Assistant

Cork University Hospital Group

January 2009 - May 2009

Research Student

Cornell University

June 2008 - September 2008

University College Dublin

June 2007 - September 2007

Quality Control Analyts

Archer Daniels Midland Company

January 2003 - June 2003

Education

DPhil (PhD) in Clinical Medicine (Ludwig Cancer Research)

University of Oxford

October 2009 - November 2014

BSc in Biomedical Science

University College Cork

September 2005 - September 2009

Bsc in Biomedical Sciences

University College Cork National University of Ireland

September 2005 - September 2009

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

D. Dersh, S. M. Jones, D. Eletto, J. C. Christianson, Y. Argon(2014). {OS}-9 facilitates turnover of nonnative {GRP}94 marked by hyperglycosylation . Molecular Biology of the Cell. 25. (15). p. 2220--2234. American Society for Cell Biology ({ASCB})

Jones S, Douarre PE, O'Leary J, Corcoran D, O'Mahony J, Lucey B, British journal of biomedical science, 2011, vol. 68, no. 3, pp. 116-119 .

STEPHANIE JONES, KEITH O'DONOGHUE, MICHAEL PETER KENNEDY, PEADAR FORBES, MIN QU(2005). A {FAST} {AND} {SIMPLE} {IMPLEMENTATION} {OF} {CHUA}{\textquotesingle}S {OSCILLATOR} {WITH} {CUBIC}-{LIKE} {NONLINEARITY} . Int. J. Bifurcation Chaos. 15. (09). p. 2959--2971. World Scientific Pub Co Pte Lt