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Nepal
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PhD Biotechnology Scientist | Animal & Microbial Genomics | Expert Scientific Writer & Data Analyst (R)
Profile Summary
Subject Matter Expertise
Services
Writing
Clinical Trial Documentation
Research
Meta-Research,
Scientific and Technical Research,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis,
Data Visualization,
Data Mining,
Data Processing,
Data Insights
Work Experience
Research Fellow
Lee Kong Chian School of Medicine
June 2021 - Present ![]()
Assistant Professor
Dayananda Sagar University
August 2017 - March 2021 ![]()
Post Doctoral Fellow
Centre for Cellular and Molecular Biology
June 2013 - July 2017 ![]()
Education
Ph.D. (School of Biological Sciences )
Nanyang Technological University
February 2005 - September 2012 ![]()
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Smeeta Shrestha, Ying Qi Goh, Guoxiang Cheam, Mingyue Yeong, Nidhi Bhayana, Abigail Thomson, Jingtao Zhang, Jia Xu, Patricia Conway, Yulan Wang (2025). Ex vivo study on prebiotic & choline combination to modulate gut bacteria, enhance choline bioavailability, and reduce TMA production . Microbiome Research Reports.
Smeeta Shrestha, Chew Leng Lim, Yu Zuan Or, Zoe Ong, Hwa Hwa Chung, Hirohito Hayashi, Shunsuke Chiba, Feng Lin, Valerie Chun Ling Lin (2020). Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism . eLife.
Guan, L., Yu, W.S., Shrestha, S., Or, Y.Z., Lufkin, T., Chan, Y.-S., Lin, V.C.L., Lim, L.W.(2020). TTC9A deficiency induces estradiol-mediated changes in hippocampus and amygdala neuroplasticity-related gene expressions in female mice . Brain Research Bulletin. 157. p. 162-168.
Lim, C.L., Or, Y.Z., Ong, Z., Chung, H.H., Hayashi, H., Shrestha, S., Chiba, S., Feng, L., Lin, V.C.L.(2020). Estrogen exacerbates mammary involution through neutrophil dependent and independent mechanism . eLife. 9. p. 1-65.
Clark, D.W., Okada, Y., Moore, K.H.S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C.L.K., Lin, K., Zhao, J.H., et al.(2019). Associations of autozygosity with a broad range of human phenotypes . Nature Communications. 10. (1).
Yadav, D.K., Shrestha, S., Lillycrop, K.A., Joglekar, C.V., Pan, H., Holbrook, J.D., Fall, C.H.D., Yajnik, C.S., Chandak, G.R.(2018). Vitamin B<inf>12</inf> supplementation influences methylation of genes associated with Type 2 diabetes and its intermediate traits . Epigenomics. 10. (1). p. 71-90.
James, P., Sajjadi, S., Tomar, A.S., Saffari, A., Fall, C.H.D., Prentice, A.M., Shrestha, S., Issarapu, P., Yadav, D.K., Kaur, L., et al.(2018). Candidate genes linking maternal nutrient exposure to offspring health via DNA methylation: A review of existing evidence in humans with specific focus on one-carbon metabolism . International Journal of Epidemiology. 47. (6). p. 1910-1937.
Yadav, D.K., Shrestha, S., Dadhwal, G., Chandak, G.R.(2018). Identification and characterization of cis-regulatory elements 'insulator and repressor' in PPARD gene . Epigenomics. 10. (5). p. 613-627.
Chandak, G.R., Silver, M.J., Saffari, A., Lillycrop, K.A., Shrestha, S., Sahariah, S.A., Di Gravio, C., Goldberg, G., Tomar, A.S., Betts, M., et al.(2017). Protocol for the EMPHASIS study; Epigenetic mechanisms linking maternal pre-conceptional nutrition and children's health in India and Sub-Saharan Africa . BMC Nutrition. 3. (1).
Khot, V.V., Yadav, D.K., Shrestha, S., Kaur, L., Sundrani, D.P., Chavan-Gautam, P.M., Mehendale, S.S., Chandak, G.R., Joshi, S.R.(2017). Hypermethylated CpG sites in the MTR gene promoter in preterm placenta . Epigenomics. 9. (7). p. 985-996.
Joshi, P.K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A.U., Schurmann, C., Smith, A.V., Zhang, W., et al.(2015). Directional dominance on stature and cognition in diverse human populations . Nature. 523. (7561). p. 459-462.
Tomar, A.S., Tallapragada, D.S., Nongmaithem, S.S., Shrestha, S., Yajnik, C.S., Chandak, G.R., Tomar, A.S., Tallapragada, D.S., Nongmaithem, S.S., Shrestha, S., et al.(2015). Intrauterine Programming of Diabetes and Adiposity . Current obesity reports. 4. (4). p. 418-428.
PREPRINT
Smeeta Shrestha, Maria Glymenaki, Sophie Curio, Mona El-Bahrawy, Yulan Wang, Nigel J. Gooderham, Nadia Guerra, Jia V. Li (2023). Tyramine promotes colon cancer risk and development by inducing DNA damage and inflammation .