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USD 120 /hr
Hire Shweta K.
India
USD 120 /hr

Precision Oncology & Biomarker Strategy Consultant | Senior Director | Computational Biology | NGS & Multi-Omics | Trans

Profile Summary
Subject Matter Expertise
Services
Writing Clinical Trial Documentation, Technical Writing
Work Experience

Senior Director

Cellworks Research (India)

- Present

Education

M.SC Biotechnology

Thapar Institute of Engineering and Technology

July 2005 - June 2007

Certifications
Publications
JOURNAL ARTICLE
(2026). Comparison of liquid versus solid tissue genomic profiling for the prediction of chemo-immunotherapy benefit in advanced NSCLC . CANCER RESEARCH.
(2026). Computational modeling of comprehensive genomic profiling to predict chemo-immunotherapy benefit in early stage NSCLC . CANCER RESEARCH.
(2026). Entrepreneurship education, entrepreneurial competencies and entrepreneurial intentions: The moderating role of lecturer competency . INNOVATIONS IN EDUCATION AND TEACHING INTERNATIONAL.
(2026). Use of an Integrative Genomics Approach to Identify Metastatic NSCLC Patients Benefiting From the Addition of Chemotherapy to Immune Checkpoint Inhibitors . CLINICAL LUNG CANCER.
(2025). Gender Identity and Mental Health Symptom Severity Among Adolescents Admitted to an Inpatient Psychiatric Hospital . CHILD PSYCHIATRY & HUMAN DEVELOPMENT.
(2025). Pilot study of an integrative telehealth group intervention for chronic pain . MEDICINE.
(2025). Therapeutic Alliance and Ruptures in Three Psychoanalytic Dyads: An Exploratory Investigation . PSYCHOANALYTIC INQUIRY.
(2025). Use of biosimulation to predict immune checkpoint inhibitor resistance in patients with high microsatellite instability . CANCER RESEARCH.
(2024). Opioid Risk Tool, in-hospital opioid exposure, and opioid demand predict pain outcomes following traumatic injury . JOURNAL OF HEALTH PSYCHOLOGY.
(2023). HPTLC profiling and hepatoprotective effect of<i> Plumeria</i><i> obtusa</i> L. against CCl4 induced liver damage in rats . ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL.
(2022). Cellworks singula therapy response index (TRI) predicts clinical outcomes for esophageal adenocarcinoma: MyCare-004. JOURNAL OF CLINICAL ONCOLOGY.
(2022). Childhood Maltreatment, Impulsive Aggression, and Suicidality Among Patients Diagnosed With Bipolar Disorder . PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY.
(2022). Differentiation Scoring (DS) Derived from Cellworks Computational Omics Biology Model (CBM) Predicts Response to Hypomethylating Agents (HMA) and Patient Survival in Myelodysplastic Syndrome (MDS) . BLOOD.
(2022). Predictions of overall survival (OS) and progression-free survival (PFS) for specific therapeutic interventions in newly diagnosed glioblastoma multiforme (GBM) using Cellworks Singula: myCare-024-04. JOURNAL OF CLINICAL ONCOLOGY.
(2022). THE IMPACT OF MISMATCH REPAIR DEFICIENCY (MMRD) ON SURVIVAL OF TEMOZOLOMIDE (TMZ)-TREATED PATIENTS WITH MGMT METHYLATED (M-MGMT) GLIOBLASTOMA (GBM): A CELLWORKS COMPUTATIONAL BIOSIMULATION PILOT STUDY. NEURO-ONCOLOGY.
(2022). Targeting chromosome 12q amplification in relapsed glioblastoma: the use of computational biological modeling to identify effective therapy-a case report . ANNALS OF TRANSLATIONAL MEDICINE.
(2022). Utility of a Brief Assessment of Opioid Demand Among Post-Discharge Trauma Care Patients . EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY.
(2021). Attachment Style Mediates the Relationship between Trauma and Somatic Distress among Individuals with Serious Mental Illness . PSYCHIATRY-INTERPERSONAL AND BIOLOGICAL PROCESSES.
(2021). Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Genomic and Molecular Markers for Decitabine (DAC) Plus Valproic-Acid (VPA) Treatment Response in Patients with Myelodysplastic Syndromes (MDS) . BLOOD.
(2021). Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Immune Modulation As a Key Pathway for Predicting Azacitidine (AZA) Response in Myelodysplastic Syndromes (MDS) . BLOOD.
(2021). Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Predicted Novel Biomarkers for Hyper- CVAD (CVAD) Treatment Response and Combination of Rituximab and Cladribine (RC) in CVAD Resistant Cases of Mantle Cell Lymphoma (MCL) . BLOOD.
(2021). Biosimulation Using the Cellworks Computational Omics Biology Model (CBM)-Based Assessment of Cytarabine (ARA-C) and Anthracycline Response and Novel Biomarker Response Criteria for the Addition of Etoposide (VP16) in Acute Myeloid Leukemia (AML) . BLOOD.
(2021). Cellworks Omics Biology Model (CBM) to predict therapy response and identify biomarkers for all-<i>trans</i> retinoic acid (ATRA) benefit as addition to induction chemotherapy in adults with acute myeloid leukemia (AML) . JOURNAL OF CLINICAL ONCOLOGY.
(2021). Combination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit . JOURNAL OF NEURO-ONCOLOGY.
(2021). Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers . CELL DEATH DISCOVERY.
(2021). Superior overall survival (OS) and disease-free survival (DFS) predictions for patients with glioblastoma multiforme (GBM) using Cellworks Singula: myCare-022-03 . JOURNAL OF CLINICAL ONCOLOGY.
(2021). Superior overall survival (OS), progression-free survival (PFS), and clinical response (CR) predictions for patients with non-small cell lung cancer (NSCLC) using Cellworks Singula: myCare-022-05 . JOURNAL OF CLINICAL ONCOLOGY.
(2021). Therapy Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Is Predictive of Individual Acute Myeloid Leukemia (AML) Patient Probability of Clinical Response (CR) and Overall Survival (OS): Mycare-023 . BLOOD.
(2020). Assessment of Cellworks Omics Biosimulation Therapy Response Predictions for Patients with Acute Myeloid Leukemia (AML) Using Cellworks Singula™: Mycare-020-01 . BLOOD.
(2020). Changes in Experimental Pain Sensitivity from Using Home-Based Remotely Supervised Transcranial Direct Current Stimulation in Older Adults with Knee Osteoarthritis . PAIN MEDICINE.
(2020). Combination chemotherapy versus temozolomide (TMZ) for patients with MGMT methylated (m-MGMT) glioblastoma (GBM): Results of cellworks omics biosimulation-MyCare-015. JOURNAL OF CLINICAL ONCOLOGY.
(2020). Comparative Analysis for Differential Drug Response between Early T-Cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) and T-Cell Acute Lymphoblastic Leukemia (T-ALL) Patients Using the Cellworks Omics Biology Model (CBM): Mycare-021-03 . BLOOD.
(2020). Monosomy 7 and Co-Occurrent Genomic Aberrations Determine Chemotherapy Response in Acute Myeloid Leukemia (AML) Patients Using the Cellworks Omics Biology Model (CBM): Mycare-021-04 . BLOOD.
(2020). Predicting Resistance to the Combination of ATO and ATRA in APL Patients with PML-Rara Fusions, Using a Computational Biology Modeling Approach: Mycare-021-01 . BLOOD.
(2020). Prediction of Clinical Response for Frontline Treatment of Acute Myeloid Leukemia (AML) Patients Using the Cellworks Omics Biology Model (CBM): Mycare-021-02 . BLOOD.
(2020). Superior Therapy Response Predictions for Patients with Myelodysplastic Syndrome (MDS) Using Cellworks Singula™: Mycare-020-02 . BLOOD.
(2020). Superior therapy response predictions for patients with acute myeloid leukemia (AML) using Cellworks Singula: MyCare-009-01. JOURNAL OF CLINICAL ONCOLOGY.
(2020). Superior therapy response predictions for patients with glioblastoma (GBM) using Cellworks Singula: MyCare-009-03. JOURNAL OF CLINICAL ONCOLOGY.
(2020). Superior therapy response predictions for patients with low-grade glioma (LGG) using Cellworks Singula: MyCare-009-04. JOURNAL OF CLINICAL ONCOLOGY.
(2020). Superior therapy response predictions for patients with myelodysplastic syndrome (MDS) using Cellworks Singula: MyCare-009-02. JOURNAL OF CLINICAL ONCOLOGY.
(2020). Superior therapy response predictions for patients with pancreatic cancer (PDAC) using Cellworks Singula: MyCare-009-05. JOURNAL OF CLINICAL ONCOLOGY.
(2020). The interactive effect of the serotonin transporter genotype and drug use on suicidal behaviors in patients diagnosed with bipolar disorder . JOURNAL OF AFFECTIVE DISORDERS.
(2019). Childhood Sexual Abuse and Suicidal Ideation Among Bipolar Patients: Existential But Not Religious Well-Being as a Protective Factor . SUICIDE AND LIFE-THREATENING BEHAVIOR.
(2018). Childhood Abuse, Intrapersonal Strength, and Suicide Resilience in African American Females who Attempted Suicide . JOURNAL OF FAMILY VIOLENCE.
(2018). Health Care Utilization for Chronic Pain in Low-Income Settings . PAIN MEDICINE.
(2018). Predicting Response to Dasatinib Using a Computational Model and Its Validation: A Beat AML Project Study . BLOOD.
(2018). Spiritual Openness, Revisiting a Potentially Important Aspect of Spirituality: Scale Review and Revision . JOURNAL OF RELIGION & HEALTH.
(2017). An Examination of Cultural Values and Pain Management in Foreign-Born Spanish-Speaking Hispanics Seeking Care at a Federally Qualified Health Center . PAIN MEDICINE.
(2017). Pain Catastrophizing, rather than Vital Signs, Associated with Pain Intensity in Patients Presenting to the Emergency Department for Pain . PAIN MANAGEMENT NURSING.
(2017). Perceived stress, depressive symptoms, and suicidal ideation in undergraduate women with varying levels of mindfulness . ARCHIVES OF WOMENS MENTAL HEALTH.
(2017). Predicting Response to CDK4/6 Inhibitors and Combinations Using a Computational Biology Model and Its Validation: A Beat AML Project Study. BLOOD.
(2017). The relationship of sociodemographic and psychological variables with chronic pain variables in a low-income population . PAIN.
(2016). Patients Presenting to the Emergency Department with Acute Pain: The Significant Role of Pain Catastrophizing and State Anxiety . PAIN MEDICINE.
(2015). Overexpression of Bcl-2 induces STAT-3 activation <i>via</i> an increase in mitochondrial superoxide . ONCOTARGET.
(2015). Psychologists' Contributions to Patient-Centered Medical Homes . JOURNAL OF CLINICAL PSYCHOLOGY IN MEDICAL SETTINGS.
(2014). <i>In silico</i> modeling predicts drug sensitivity of patient-derived cancer cells . JOURNAL OF TRANSLATIONAL MEDICINE.
(2014). A Novel and Personalized Method Using Simulation for Predicting Effective Therapeutics for Waldenstroms Macroglobulinemia . BLOOD.
(2014). Clinical translation pathway for identifying patient-specific dregs based on predictive simulation outcomes with ex vivo validation . JOURNAL OF CLINICAL ONCOLOGY.
(2014). Individualized therapy identified using simulation for bortezomib resistant patient with <i>ex</i>-<i>vivo</i> validation . CANCER RESEARCH.
(2014). Predicting GBM response to targeted therapeutics using simulation with ex vivo validations . JOURNAL OF CLINICAL ONCOLOGY.
(2014). Predictive Simulation Approach for Designing Cancer Therapeutic Regimens with Novel Biological Mechanisms . JOURNAL OF CANCER.
(2014). β-Caryophyllene Oxide Inhibits Constitutive and Inducible STAT3 Signaling Pathway Through Induction of the SHP-1 Protein Tyrosine Phosphatase . MOLECULAR CARCINOGENESIS.
(2013). Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3 . BRITISH JOURNAL OF PHARMACOLOGY.
(2013). Ex Vivo Patient-Specific Validation Of Personalized Therapeutic Designed For Multiple Myeloma . BLOOD.
(2013). Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer (vol 287, pg 38028, 2012) . JOURNAL OF BIOLOGICAL CHEMISTRY.
(2013). STAT3 phosphorylation and Bcl-2 expression as a predictive signature for stratifying clinical lymphomas . CANCER RESEARCH.
(2012). Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1 . JOURNAL OF CELLULAR PHYSIOLOGY.
(2012). Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer . JOURNAL OF BIOLOGICAL CHEMISTRY.
(2012). PAIN REFERENCES USED IN A TRAIT CATASTROPHIZING MEASURE. ANNALS OF BEHAVIORAL MEDICINE.
(2012). PSYCHOSOCIAL PREDICTORS OF HEALTH CARE UTILIZATION IN CHRONIC PAIN PATIENTS IN RURAL ALABAMA. ANNALS OF BEHAVIORAL MEDICINE.
(2012). Rational Design of a Therapeutic Program for Multiple Myeloma Using a Strategy of Drug Repurposing and Combination Therapy . BLOOD.
(2012). STAT3 is a critical mediator of the pro-survival effect of Bcl-2-Rac1 interaction in human cancer cells . CANCER RESEARCH.
(2012). THE ROLE OF SPIRITUALITY IN SATISFACTION WITH COMPLEMENTARY AND ALTERNATIVE MEDICINE. ANNALS OF BEHAVIORAL MEDICINE.
(2011). A Qualitative Analysis of a Randomized Controlled Trial Comparing a Cognitive-Behavioral Treatment With Education . JOURNAL OF PAIN.
(2011). Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells . BRITISH JOURNAL OF PHARMACOLOGY.
(2011). Dual epidermal growth factor receptor (EGFR)/insulin-like growth factor-1 receptor (IGF-1R) inhibitor: A novel approach for overcoming resistance in anticancer treatment . EUROPEAN JOURNAL OF PHARMACOLOGY.
(2011). Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4 . MOLECULAR CANCER.
(2011). Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma <i>In Vivo</i> . CLINICAL CANCER RESEARCH.
(2011). Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice . JOURNAL OF MOLECULAR MEDICINE-JMM.
(2010). Assessment of viscoelasticity and hydration effect of herbal moisturizers using bioengineering techniques . PHARMACOGNOSY MAGAZINE.
(2010). Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by <i>Nanoparticle</i> <i>Albumin</i>-<i>Bound</i>-Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma . MOLECULAR CANCER THERAPEUTICS.
(2009). Age Dependent Studies as Various Skin Parameters Using Cutometer. INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH.
(2008). Novel preparation and evaluation of lotion containing aloe gel beads. INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH.
(2007). 3D QSAR analysis of PPAR-γ agonist and PTPIB antagonist as anti-hyperglycemic agents. ASIAN JOURNAL OF CHEMISTRY.