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★★★★★
☆☆☆☆☆
USD 50 /hr
Hire Dr. Shiv K. S.
Finland
USD 50 /hr

An experienced biochemist, protein scientist and structural biologist with over 8 years of experience.

Profile Summary
Subject Matter Expertise
Services
Writing Technical Writing, Copywriting
Research Market Research, User Research, Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review
Consulting Digital Strategy Consulting, Scientific and Technical Consulting, Regulatory Consulting
Data & AI Predictive Modeling, Data Visualization, Big Data Analytics, Data Processing, Data Insights
Product Development Formulation, Product Evaluation, Material Sourcing, Product Validation, Manufacturing, Concept Development, Prototyping
Work Experience

University of Helsinki

- Present

Postdoctoral Research Fellow

University of Helsinki

November 2023 - Present

Research Associate

University of Cambridge

September 2022 - November 2023

Postdoctoral Researcher

University of Oulu

August 2020 - August 2022

Doctoral Researcher

University of Oulu

January 2015 - May 2020

Doctoral Candidate

University of Oulu

April 2015 - April 2020

Research Assistant

University of Oulu

February 2014 - March 2015

Education

PhD , Biochemistry (Faculty of Biochemistry and Molecular Medicine)

University of Oulu

January 2015 - August 2020

MSc. in Protein science and biotechnology (Department of Biochemistry)

University of Oulu

September 2012 - October 2014

BSc. 4year (Department of Biochemistry, Universal Science college)

Pokhara University

September 2007 - June 2011

Certifications
  • Biochemistry

    Brainbench

    March 2017 - Present

Publications
JOURNAL ARTICLE
Brooke A. Brown, Paul J. Myers, Sara J. Adair, Jason R. Pitarresi, Shiv K. Sah-Teli, Logan A. Campbell, William S. Hart, Michelle C. Barbeau, Kelsey Leong, Nicholas Seyler, et al. (2024). A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreatic cancer . Cancer Research.
Brennan Wadsworth, Marina Leiwe, Eleanor A Minogue, Pedro P. Cunha, Viktor Engman, Carolin Brombach, Christos Asvestis, Shiv K Sah-Teli, Emilia Marklund, Peppi Karppinen, et al. (2023). A 2-Hydroxybutyrate- mediated feedback loop regulates muscular fatigue . eLife.
Jason S. Shapiro, Hsiang-Chun Chang, Yuki Tatekoshi, Zibo Zhao, Zohra Sattar Waxali, Bong Jin Hong, Haimei Chen, Justin A Geier, Elizabeth Bartom, Adam De Jesus, et al.(2023). Iron drives anabolic metabolism through active histone demethylation and mTORC1 . Nature Cell Biology. Springer Science and Business Media {LLC}
Eleanor Minogue, Pedro P. Cunha, Brennan J. Wadsworth, Guinevere L. Grice, Shiv K. Sah-Teli, Rob Hughes, David Bargiela, Alessandro Quaranta, Javier Zurita, Robin Antrobus, et al. (2023). Glutarate regulates T cell metabolism and anti-tumour immunity . Nature Metabolism.
Shiv K. Sah-Teli, Matyas Pinkas, Mikko J. Hynönen, Sarah J. Butcher, Rik K. Wierenga, Jiri Novacek, Rajaram Venkatesan (2023). Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial β-oxidation trifunctional enzymes . Structure.
Tuulia Ala‐Nisula, Shiv K. Sah‐Teli, Veli‐Pekka Ronkainen, Elitsa Y. Dimova, Peppi Koivunen (2023). Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism . FEBS Letters.
Ala-Nisula, Tuulia, Sah-Teli, Shiv K., Ronkainen, Veli-Pekka, Dimova, Elitsa Y., Koivunen, Peppi (2023). Human phytanoyl-CoA dioxygenase domain-containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism . FEBS Letters.
Minogue, Eleanor, Cunha, Pedro P., Wadsworth, Brennan J., Grice, Guinevere L., Sah-Teli, Shiv K., Hughes, Rob, Bargiela, David, Quaranta, Alessandro, Zurita, Javier, Antrobus, Robin, et al. (2023). Glutarate regulates T cell metabolism and anti-tumour immunity . Nature Metabolism.
Shapiro, Jason S., Chang, Hsiang-Chun, Tatekoshi, Yuki, Zhao, Zibo, Waxali, Zohra Sattar, Hong, Bong Jin, Chen, Haimei, Geier, Justin A., Bartom, Elizabeth T., De Jesus, Adam, et al. (2023). Iron drives anabolic metabolism through active histone demethylation and mTORC1 . Nature Cell Biology.
Sah-Teli, Shiv K., Pinkas, Matyas, Hynonen, Mikko J., Butcher, Sarah J., Wierenga, Rik K., Novacek, Jiri, Venkatesan, Rajaram (2023). Structural basis for different membrane-binding properties of<i> E.</i><i> coli</i> anaerobic and human mitochondrial 8-oxidation trifunctional enzymes . Structure.
Brown, Brooke A, Myers, Paul J., Adair, Sara J., Pitarresi, Jason R., Sah-Teli, Shiv K., Hart, William S., Barbeau, Michelle, Leong, Kelsey, Seyler, Nicholas, Kane, William, et al. (2022). A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer . BioRxiv.
Jahangir Alam, Farah Tazkera Rahman, Shiv K. Sah-Teli, Rajaram Venkatesan, M. Kristian Koski, Kaija J. Autio, J. Kalervo Hiltunen, Alexander J. Kastaniotis(2021). Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae . Acta Crystallographica Section D Structural Biology. 77. (6). p. 840--853. International Union of Crystallography ({IUCr})
Alam, Jahangir, Rahman, Farah Tazkera, Sah-Teli, Shiv K., Venkatesan, Rajaram, Koski, M. Kristian, Autio, Kaija J., Hiltunen, J. Kalervo, Kastaniotis, Alexander J. (2021). Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from <i>Saccharomyces cerevisiae</i> . Acta Crystallographica Section D Structural Biology.
Shiv K. Sah-Teli, Mikko J. Hyn&#246;nen, Ramita Sulu, Subhadra Dalwani, Werner Schmitz, Rik K. Wierenga, Rajaram Venkatesan(2020). Insights into the stability and substrate specificity of the E. coli aerobic β-oxidation trifunctional enzyme complex . Journal of Structural Biology. 210. (3). p. 107494. Elsevier {BV}
Sah-Teli, Shiv Kumar, Hynonen, Mikko, Sulu, Ramita, Dalwani, Subhadra, Schmitz, Werner, Wierenga, Rik, Venkatesan, Rajaram (2020). Insights into the stability and substrate specificity of the <i>E. coli</i> aerobic β-oxidation trifunctional enzyme complex . Journal of Structural Biology.
Shiv K. Sah-Teli, Mikko J. Hyn&#246;nen, Werner Schmitz, James A. Geraets, Jani Seitsonen, Jan Skov Pedersen, Sarah J. Butcher, Rik K. Wierenga, Rajaram Venkatesan(2019). Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic β-oxidation trifunctional enzyme complexes . Biochemical Journal. 476. (13). p. 1975--1994. Portland Press Ltd.
Murthy AV, Sulu R, Koski MK, Tu H, Anantharajan J, Sah-Teli SK, Myllyharju J, Wierenga RK(2018). Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): high affinity peptides have a PxGP sequence motif . Protein science : a publication of the Protein Society.
Venkatesan, R., Sah-Teli, S.K., Awoniyi, L.O., Jiang, G., Prus, P., Kastaniotis, A.J., Hiltunen, J.K., Wierenga, R.K., Chen, Z.(2014). Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase . Nature Communications. 5.
PREPRINT
Brooke A. Brown, Paul J. Myers, Sara J. Adair, Jason R. Pitarresi, Shiv K. Sah-Teli, Logan A. Campbell, William S. Hart, Michelle Barbeau, Kelsey Leong, Nicholas Seyler, et al. (2022). A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer .