Want to hire this expert for a project? Request a quote for free.
USD 40 /hr
Hire Dr. Sarah M.
USD 40 /hr
Subject Matter Expertise
University of Sussex
July 2004 - July 2012
GlaxoSmithKline Research and Development
September 2000 - July 2004
Education details not provided.
- Certification details not provided.
(2016). A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct . Oncotarget.
(2016). Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2 . The Biochemical journal.
(2014). Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors . Analytical biochemistry.
(2012). Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome . PLoS genetics.
(2011). Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome . Nature genetics.
(2009). XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation . Nucleic acids research.
(2008). Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling . Nature genetics.
(2007). Chromosome breakage after G2 checkpoint release . The Journal of cell biology.
(2006). ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling . The EMBO journal.
(2006). DNA-PK autophosphorylation facilitates Artemis endonuclease activity . The EMBO journal.
(2006). Identification of a novel motif in DNA ligases exemplified by DNA ligase IV . DNA repair.
(2005). Biophotonic imaging in HO-1.luc transgenic mice: real-time demonstration of gender-specific chloroform induced renal toxicity . Mutation research.